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| 1 | Effect of Wuziyanzong Pill on sperm quality and calcium ion content in oligoasthenospermia rats显示文摘OBJECTIVE:To study the effect of Wuziyanzong treatment on the sperm quality and content of calcium ions(Ca 2+) in oligoasthenospermia rats.METHODS:A model of oligoasthenospermia was induced in 50 Sprague Dawley rats by treatment with tripterygium glycosides at 30 mg/kg per day for 8 weeks.They were divided randomly into a model group,a positive group(Huangjingzanyu capsule,3.01 g/kg),and low,medium and high dose Wuziyanzong treatment groups(2.30,4.60,9.20 g/kg crude drug respectively) with 10 in each group.Another 10 rats were used as a control group.The rats in the control and model groups were administered distilled water,while the rats in the remaining groups were administered Wuziyanzong for 30 d.The epididymides were removed,spermatozoa recovered and the sperm density and viability were measured.The spermatozoa were purified and the contents of Ca 2+ in the cytoplasm and mitochondria were detected by flow cytometry and atomic absorption spectrometry,respectively.RESULTS:After 8 weeks of treatment with tripterygium glycosides,the sperm density,sperm activity and the Ca 2 + content of spermatozoa in the model rats were all significantly decreased compared with the control group(all P<0.05).After 30 d treatment,the sperm density and activity improved and the Ca 2 + content of sperm were increased significantly in the medium and high dose Wuziyanzong treatment groups in comparison with the model group(all P<0.05).CONCLUSION:The Wuziyanzong treatment increased sperm density,improved sperm viability and enhanced the content of Ca 2+ in the sperm cytoplasm and mitochondria in this rat model of oligoasthenospermia. | Tongsheng Wang Jinling Huang Deling Wu Qing Li Xiangguo Liu Han Chen Lei Qiao Dongdong Li Jun Li | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 11 |
| 2 | An efficient and fast polarity optimization approach for mixed polarity Reed-Muller logic circuits显示文摘尽管基因算法广泛地在混合极性芦苇思考(MPRM ) 逻辑电路的极性优化被使用了,很少研究考虑了极性变换顺序。以便改进 MPRM 逻辑电路的极性优化的效率,我们就极性变换顺序而言建议一条有效、快的极性优化途径(FPOA ) 。第一,在 FPOA 后面的主要想法是那等评估的极性集合的最好的极性变换顺序被使用建议混合基因算法(HGA ) 获得;第二,每在极性集合的极性根据 HGA 获得的最好的极性变换顺序被变换。我们的建议 FPOA 在 C 被实现,比较分析为 MCNC 基准电路被介绍了。试验性的结果证明为有更多的变量的电路, FPOA 在与极性变换顺序和改进极性优化与启发式的技术接近疏忽的传统的极性优化途径相比改进 MPRM 逻辑电路的极性优化的效率是高度有效的。 | Zhenxue HE Limin XIAO Fei GU Tongsheng XIA Shubin SU Zhisheng HUO Rong ZHANG Longbing ZHANG Li RUAN Xiang WANG | 2017 | Frontiers of Computer Science2017，11，4： | 6 |
| 3 | HSPOG:An Optimized Target Recognition Method Based on Histogram of Spatial Pyramid Oriented Gradients显示文摘The Histograms of Oriented Gradients(HOG)can produce good results in an image target recognition mission,but it requires the same size of the target images for classification of inputs.In response to this shortcoming,this paper performs spatial pyramid segmentation on target images of any size,gets the pixel size of each image block dynamically,and further calculates and normalizes the gradient of the oriented feature of each block region in each image layer.The new feature is called the Histogram of Spatial Pyramid Oriented Gradients(HSPOG).This approach can obtain stable vectors for images of any size,and increase the target detection rate in the image recognition process significantly.Finally,the article verifies the algorithm using VOC2012 image data and compares the effect of HOG. | Shaojun Guo Feng Liu Xiaohu Yuan Chunrong Zou Li Chen Tongsheng Shen | 2021 | Tsinghua Science and Technology2021，26，4： | 3 |
| 4 | Hymecromone:a clinical prescription hyaluronan inhibitor for efficiently blocking COVID-19 progression显示文摘Currently,there is no effective drugs for treating clinically COVID-19 except dexamethasone.We previously revealed that human identical sequences of SARS-CoV-2 promote the COVID-19 progression by upregulating hyaluronic acid(HA).As the inhibitor of HA synthesis,hymecromone is an approved prescription drug used for treating biliary spasm.Here,we aimed to investigate the relation between HA and COVID-19,and evaluate the therapeutic effects of hymecromone on COVID-19.Firstly,HA was closely relevant to clinical parameters,including lymphocytes(n=158;r=−0.50;P<0.0001),C-reactive protein(n=156;r=0.55;P<0.0001),D-dimer(n=154;r=0.38;P<0.0001),and fibrinogen(n=152;r=0.37;P<0.0001),as well as the mass(n=78;r=0.43;P<0.0001)and volume(n=78;r=0.41;P=0.0002)of ground-glass opacity,the mass(n=78;r=0.48;P<0.0001)and volume(n=78;r=0.47;P<0.0001)of consolidation in patient with low level of hyaluronan(HA<48.43 ng/mL).Furthermore,hyaluronan could directly cause mouse pulmonary lesions.Besides,hymecromone remarkably reduced HA via downregulating HAS2/HAS3 expression.Moreover,89%patients with hymecromone treatment had pulmonary lesion absorption while only 42%patients in control group had pulmonary lesion absorption(P<0.0001).In addition,lymphocytes recovered more quickly in hymecromone-treated patients(n=8)than control group(n=5)(P<0.05).These findings suggest that hymecromone is a promising drug for COVID-19 and deserves our further efforts to determine its effect in a larger cohort. | Shuai Yang Yun Ling Fang Zhao Wei Li Zhigang Song Lu Wang Qiuting Li Mengxing Liu Ying Tong Lu Chen Daoping Ru Tongsheng Zhang Kaicheng Zhou Baolong Zhang Peng Xu Zhicong Yang Wenxuan Li Yuanlin Song Jianqing Xu Tongyu Zhu Fei Shan Wenqiang Yu Hongzhou Lu | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 2 |
| 5 | Structural characteristics and hydration kinetics of modified steel slag显示文摘 | Jianxin Li Qijun Yu Jiangxiong Wei Tongsheng Zhang | 2010 | Cement and Concrete Research2010，，3： | 2 |
| 6 | Mechanical and tribological properties of PA/PPS blends 显示文摘 | CHEN Zhaobin LI Tongsheng YANG Yuliang | 2004 | Wear2004，257，： | 1 |
| 7 | Mechanical and Tribological Properties of PA/PPS Blends显示文摘 | Zhaobin Chen Tongsheng Li Yuliang Yang | 2004 | Wear2004，257，： | 1 |
| 8 | A Study on the Friction and Wear Behavior of PTFE Filled with Acid Treated Nano-Attapugite显示文摘 | Lai Shiquan Li Tongsheng | 2005 | Macromolecular Materials and Engineering2005，289，10： | 1 |
| 9 | Mechanical and tribologieal properties of PA/PPS blends 显示文摘 | Chen Zhaobin Li Tongsheng Yang Yuliang | 2004 | Wear2004，257，7： | 1 |
| 10 | Spatial Heterogeneity of Agricultural Science and Technology Parks Technology Diffusion: A Case Study of Yangling ASTP显示文摘Agricultural science and technology parks(ASTPs) represent an important growth pole in China’s agricultural modernization.Clarifying their diffusion laws can optimize the technological diffusion process and improve its efficiency. Our study uses disaggregated spatial information in its model to analyze ASTP technology diffusion in a heterogeneous space. We constructed a comprehensive index system to evaluate the diffusion environmental quality and introduced the heterogeneous diffusion equation to calculate the technological diffusion probability. We applied this framework to a real-world scenario: the apple planting technology diffusion of the Yangling ASTP in the Loess Plateau, China. The results indicated: (1)the technological diffusion environment of the Loess Plateau advantageous apple producing area showed strong spatial heterogeneity caused by climate, topography, and external transportation links.(2) Under the combined effects of distance and spatial heterogeneity, the spatial diffusion pattern of the Yangling ASTP apple technology was expansion diffusion supplemented by hierarchical diffusion and banded diffusion, and (3) ASTP technology diffusion showed a strong distance attenuation effect, and the frictional effect of distance can be decreased by improving the diffusion environmental quality. These laws can promote regional balanced ASTP-driven development. | WANG Zhao LIU Jianhong LI Tongsheng REN Wanying RUI Yang | 2021 | Chinese Geographical Science2021，31，4： | 1 |
| 11 | Nickel-catalyzed Construction of Heat Conductive Network in Electrically Calcined Anthracite (ECA) Based Carbon Blocks显示文摘Nickel nitrate was introduced into carbon blocks by using ECA aggregates as catalyst-carrier.The Ni-containing anthracite aggregates were firstly prepared by mixing anthracite aggregates in nickel nitrate ethanol solution and then incorporated into carbon blocks after pre-treating.The phase composition,microstructure and properties of all carbon blocks fired at 1 000℃or 1 400℃in a coke bed were studied with the aid of an X-ray diffractomer,a field emission scanning electron microscope,a mercury porosimetry and a laser thermal conductivity meter.The results showed that the addition of Ni-containing anthracite aggregates promoted the formation of one-dimensional nanocarbon andβ-SiC whiskers at 1 000℃and the growth ofβ-Sialon at 1 400℃,respectively.Moreover,the cold compressive strength and microporosity characteristics of the carbon blocks with the addition of Ni-containing anthracite aggregates were enhanced and the thermal conductivity was remarkably improved attributing to the high heat conductive network formed by the ceramic phases. | WANG Tongsheng LI Yawei SANG Shaobai | 2017 | China's Refractories2017，26，1： | 1 |
| 12 | Tribophysical and tribochemical effects of a thermoplastic polyimide 显示文摘 | LI Tongsheng CONG Peihong LIU Xujun | 2000 | Journal of Materials Science2000，35，： | 1 |
| 13 | Design and Preparation of High Elastic Modulus Self-compacting Concrete for Pre-stressed Mass Concrete Structures显示文摘Requirements of self-compacting concrete(SCC) applied in pre-stressed mass concrete structures include high fluidity, high elastic modulus, low adiabatic temperature rise and low drying shrinkage, which cannot be satisfied by ordinary SCC. In this study, in order to solve the problem, a few principles of SCC design were proposed and the effects of binder amount, fly ash(FA) substitution, aggregate content and gradation on the workability, temperature rise, drying shrinkage and elastic modulus of SCC were investigated.The results and analysis indicate that the primary factor influencing the fluidity was paste content, and the main methods improving the elastic modulusof SCC were a lower sand ratio and an optimized coarse aggregate gradation. Lower adiabatic temperature rise and drying shrinkage were beneficial for decreasing the cement content. Further, based on the optimization of mixture, a C50 grade SCC(with binder amount of only 480 kg/m3, fly ash substitution of 40%, sand ratio of 51% and proper coarse aggregate gradation(V5-10 mm: V10-16 mm: V16-20 mm= 30%: 30%:40%)) with superior workability was successfully prepared. The temperature rise and drying shrinkage of the prepared SCC were significantly reduced, and the elastic modulus reached 37.6 GPa at 28 d. | 祝雯 CHEN Yang LI Fangxian ZHANG Tongsheng HU Jie 韦江雄 YU Qijun | 2016 | Journal of Wuhan University of Technology(Materials Science)2016，31，3： | 1 |
| 14 | The tribological properties of PTFE filled with thermally treated nano-attapulgite 显示文摘 | Lai Shiquan Li Tongsheng Liu Xujun | 2006 | Tribology International2006，39，6： | 1 |
| 15 | The effect of silica size on the friction and wear behaviors of polyimide/silica hybrids by sol-gel processing显示文摘 | Lai Shiquan Li Tongsheng | 2007 | Wear2007，，262： | 1 |
| 16 | Mapping paddy rice in Jiangsu Province,China,based on phenological parameters and a decision tree model显示文摘Timely and accurate mapping of rice planting areas is crucial under China's current cropping structure. This study proposes a new paddy rice mapping method by combining phenological parameters and a decision tree model.Six phenological parameters were developed to identify paddy rice areas based on the analysis of the Moderate Resolution Imaging Spectroradiometer (MODIS)Enhanced Vegetation Index (EVI)time series and the Land Surface Water Index (LSWI)time series.The six phenological parameters considered the performance of different land cover types during specific phenological phases (EVI1 and EVI2),one-half of or the entire rice growing cycle (LSWI1 and LSWI2),and the shape of the LSWI time series (KurtosisLSWI and SkewnessLSWI).A hierarchical decision tree model was designed to classify paddy rice areas according to the potential separability of different land cover types in paired phenological parameter spaces.Results showed that the decision tree model was more sensitive to LSWI1,LSWI2,and SkewnessLswi than the other phenological parameters.A paddy rice map of Jiangsu Province for 2015 was generated with an optimal threshold set of(0.4,0.42,9,19,1.5,-1.7,0.0)with a total accuracy of 93.9%.The MODIS-derived paddy rice map generally agreed with the paddy land fraction map from the National Land Cover Dataset project,but there were regional discrepancies because of their different definitions of land use and the inability of MODIS to map paddy rice at a fragmental level.The MODIS-derived paddy rice map showed high correlation (R^2=0.85)with county-level agricultural statistics.The results of this study indicate that the phenological parameter-based paddy rice mapping algorithm could be applied at larger spatial scales. | Jianhong LIU Le LI Xin HUANG Yongmei LIU Tongsheng LI | 2019 | Frontiers of Earth Science2019，13，1： | 1 |
| 17 | Evidence for solar forcing of climate variation from δ18O of peat cellulose显示文摘 | Liu Tongsheng Jiang Hongbo Zhou Liping Hong Bing Zhu Yongxuan Li Handing Leng Xuetian Qin Xiaoquang Wang Yu Lin Qinghua Zeng Yiqiang | 2000 | Science in China (Series D)2000，43，2： | 1 |
| 18 | The tribological properties of PTFE filled with thermally treated nano-attapulgite 显示文摘 | Lai Shiquan Li Tongsheng Liu Xujun | 2006 | Tribology International2006，39，6： | 1 |
| 19 | Optimization methods of production layer combination for coalbed methane development in multi-coal seams显示文摘Based on the productivity equation of coalbed methane(CBM) wells, three indexes, main production layer optimization index, main production layer expansion index and capacity contribution index are proposed, with which the three-step optimization method of production-layer combination is established. In selecting main production layer, the coal seam thickness, CBM content, coal seam permeability, coal seam reservoir pressure and coal structure are considered comprehensively to evaluate the potential of the production layer. In selecting expansion of the main production layer combination, on the premise of ensuring full and slow desorption of the main production layer and non-exposure of the main production layer out of liquid surface, the degree of mutual interference between the main and non-main production layers is comprehensively evaluated by coupling the critical desorption pressure, layer spacing and reservoir pressure gradient difference. In optimizing production layer combination, the main concern is the economic efficiency of the combined layers. Only when the contribution coefficient of the main production layer is greater than 30% and the contribution index of the other production layers is more than 10%, the economic benefit of a CBM well after being put into production can be ensured. Based on the comparative analysis of the development effect of the development test wells in Songhe of Guizhou province, it is proved that the 'three-step method' for the optimization of production-layer combination is scientific and practical, and can be used to design the multi-layer commingling scheme of coalbed methane. | YANG Zhaobiao ZHANG Zhengguang QIN Yong WU Congcong YI Tongsheng LI Yangyang TANG Jun CHEN Jie | 2018 | Petroleum Exploration and Development2018，45，2： | 1 |
| 20 | The role of products of tribochemical reactions on the friction and wear properties of alumina/silicon carbide couple sliding in HFC-134a gas显示文摘 | Peihong Cong Kimihire Kobaynshi Tongsheng Li | 2002 | Wear2002，252，： | 1 |
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