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| 1 | Nature:研究鉴定出侵袭性胰腺癌细胞及其弱点显示文摘在一项新的研究中,来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植(patient—derived tumorxenograft,PDx)和模式小鼠开展一系列临床前实验,鉴定出一种门卫蛋白(gatekee Perprotein)阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型,并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。 | Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, Andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda | 2017 | 现代生物医学进展2017，17，14： | 2 |
| 2 | MicroRNA expression profiles of esophageal cancer显示文摘 | Andrew Feber Liqiang Xi James D. Luketich Arjun Pennathur Rodney J. Landreneau Maoxin Wu Scott J. Swanson Tony E. Godfrey Virginia R. Litle | 2008 | The Journal of Thoracic and Cardiovascular Surgery2008，，2： | 2 |
| 3 | Cholesterol as a versatile platform for chiral recognition显示文摘 | Tony D. James Hirosuke Kawabata Rainer Ludwig Kazutaka Murata Seiji Shinkai | 1994 | Tetrahedron1994，，2： | 1 |
| 4 | Ultrahigh-resolution and 3-dimensional optical coherence tomography ex vivo imaging of the large and small intestines <ce:link locator='fx1'/>显示文摘 | Pei-Lin Hsiung Liron Pantanowitz Aaron D. Aguirre Yu Chen Darshan Phatak Tony H. Ko Stephane Bourquin Stuart J. Schnitt Sugrah Raza James L. Connolly Hiroshi Mashimo James G. Fujimoto | 2005 | Gastrointestinal Endoscopy2005，，4： | 1 |
| 5 | Comparative Genomics of Esophageal Adenocarcinoma and Squamous Cell Carcinoma显示文摘 | Santhoshi Bandla Arjun Pennathur James D. Luketich David G. Beer Lin Lin Adam J. Bass Tony E. Godfrey Virginia R. Litle | 2012 | The Annals of Thoracic Surgery2012，，4： | 1 |
| 6 | A simple umbelliferone based fluorescent probe for the detection of nitroreductase显示文摘简单 nitrobenzyl-umbelliferone (NCOU1 ) 是包含 nitroreductase (NTR ) 的 synthesised 扳机一半。NTR 的存在,经由 nitro 组的催化 NTR 的减小导致了父母分子的破碎和高度放射性的 fluorophore umbelliferone 的版本。面对 NTR 酶, NCOU1 在 455 nm 在荧光紧张产生了 5 褶层增加并且为在另外的减少的酶上的 NTR 是选择的。这些结果显示 NCOU1 能为 NTR 的察觉被用作简单试金。 | Adam C. Sedgwick Alex Hayden Barry Hill Steven D. Bull Robert B. P. Elmes Tony D. James | 2018 | Frontiers of Chemical Science and Engineering2018，12，2： | 1 |
| 7 | Membrane anchored serine proteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer显示文摘 | Sarah Netzel-Arnett John D. Hooper Roman Szabo Edwin L. Madison James P. Quigley Thomas H. Bugge Toni M. Antalis | 2003 | Cancer and Metastasis Reviews (-)2003，，2： | 1 |
| 8 | A Novel Hepacivirus with an Unusually Long and Intrinsically Disordered NS5A Protein in a Wild Old World Primate显示文摘 | Michael Lauck Samuel D. Sibley James Lara Michael A. Purdy Yury Khudyakov David Hyeroba Alex Tumukunde Geoffrey Weny William M. Switzer Colin A. Chapman Austin L. Hughes Thomas C. Friedrich David H. O’Connor Tony L. Goldberg | 2013 | Journal of Virology2013，，16： | 1 |
| 9 | Light controlled imaging probes for intracellular target recognition: photochromism as a tool to enhance sensing precision显示文摘Chemosensors and imaging probes have been the focus of significant research interest over the past few decades.In part due to ease of preparation and simplicity in manipulation,fluorescent probes have been extensively used for biomedical applications.When used for in vitro cell imaging[1,2]。 | Tony D. James | 2017 | Science China Chemistry2017，60，12： | 0 |
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