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| 1 | Managements of recurrent hepatocellular carcinoma after liver transplantation: A systematic review显示文摘AIM: To investigate the efficacy(survival) and safety of treatments for recurrent hepatocellular carcinoma(HCC) in liver transplantation(LT) patients.METHODS: Literature search was performed on available online databases without a time limit until January 2015. Clinical studies describing survival after HCC recurrence in LT patients were retrieved for a fulltext evaluation. A total of 61 studies were selected: 13 case reports, 41 retrospective case series, and 7 retrospective comparative studies.RESULTS: Based on all included studies, the mean HCC recurrence rate was 16% of all LTs for HCC. A total of 1021 LT patients experienced HCC recurrence. The median time from LT to HCC recurrence was 13 mo(range 2-132 mo). The majority of patients(67%) presented with HCC extra-hepatic recurrences, involving lung, bone, adrenal gland, peritoneal lymph nodes, and rarely the brain. Overall survival after HCC recurrence was 12.97 mo. Surgical resection of localized HCC recurrence and Sorafenib for controlling systemic spread of HCC recurrence were associated with the higher survival rates(42 and 18 mo, res-pectively). However, Sorafenib, especially when combined with m TOR, was frequently associated with severe side effects that required dose reduction or discontinuation CONCLUSION: Management of recurrent HCC in LT patients is challenging and associated with poor prognosis independently of the type of treatment. | Nicola de'Angelis Filippo Landi Maria Clotilde Carra Daniel Azoulay | 2015 | World Journal of Gastroenterology2015，21，39： | 42 |
| 2 | International consensus statement on robotic hepatectomy surgery in 2018显示文摘The robotic surgical system has been applied in liver surgery. However,controversies concerns exist regarding a variety of factors including the safety,feasibility, efficacy, and cost-effectiveness of robotic surgery. To promote the development of robotic hepatectomy, this study aimed to evaluate the current status of robotic hepatectomy and provide sixty experts' consensus and recommendations to promote its development. Based on the World Health Organization Handbook for Guideline Development, a Consensus Steering Group and a Consensus Development Group were established to determine the topics, prepare evidence-based documents, and generate recommendations. The GRADE Grid method and Delphi vote were used to formulate the recommendations. A total of 22 topics were prepared analyzed and widely discussed during the 4 meetings. Based on the published articles and expert panel opinion, 7 recommendations were generated by the GRADE method using an evidence-based method, which focused on the safety, feasibility, indication,techniques and cost-effectiveness of hepatectomy. Given that the current evidences were low to very low as evaluated by the GRADE method, further randomized-controlled trials are needed in the future to validate these recommendations. | Rong Liu Go Wakabayashi Hong-Jin Kim Gi-Hong Choi Anusak Yiengpruksawan Yuman Fong Jin He Ugo Boggi Roberto I Troisi Mikhail Efanov Daniel Azoulay Fabrizio Panaro Patrick Pessaux Xiao-Ying Wang Ji-Ye Zhu Shao-Geng Zhang Chuan-Dong Sun Zheng Wu Kai-Shan Tao Ke-Hu Yang Jia Fan Xiao-Ping Chen | 2019 | World Journal of Gastroenterology2019，25，12： | 23 |
| 3 | Liver Transplantation for Neuroendocrine Tumors in Europe—Results and Trends in Patient Selection: A 213-Case European Liver Transplant Registry Study显示文摘 | Yves Patrice Le Treut Emilie Grégoire Jürgen Klempnauer Jacques Belghiti Elisabeth Jouve Jan Lerut Denis Castaing Olivier Soubrane Olivier Boillot Georges Mantion Kia Homayounfar Manuel Bustamante Daniel Azoulay Philippe Wolf Marek Krawczyk Andreas Pasche | 2013 | Annals of Surgery2013，，5： | 3 |
| 4 | A Hepatocellular Carcinoma 5-Gene Score Associated With Survival of Patients After Liver Resection显示文摘 | Jean–Charles Nault Aurélien De Reyniès Augusto Villanueva Julien Calderaro Sandra Rebouissou Gabrielle Couchy Thomas Decaens Dominique Franco Sandrine Imbeaud Francis Rousseau Daniel Azoulay Jean Saric Jean–Frédéric Blanc Charles Balabaud Paulette Bioulac | 2013 | Gastroenterology2013，，1： | 3 |
| 5 | Tumor Progression While on Chemotherapy: A Contraindication to Liver Resection for Multiple Colorectal Metastases?显示文摘 | René Adam Gerard Pascal Denis Castaing Daniel Azoulay Valerie Delvart Bernard Paule Francis Levi Henri Bismuth | 2004 | Annals of Surgery2004，，6： | 2 |
| 6 | Hepatic resection for hepatocellular carcinoma in patients with C hild– P ugh’s A cirrhosis: is clinical evidence of portal hypertension a contraindication?显示文摘 | Roberto Santambrogio Michael D. Kluger Mara Costa Andrea Belli Matteo Barabino Alexis Laurent Enrico Opocher Daniel Azoulay Daniel Cherqui | 2012 | HPB2012，，1： | 2 |
| 7 | Therapeutic Strategies in Symptomatic Portal Biliopathy显示文摘 | Eric Vibert Daniel Azoulay Thomas Aloia Gérard Pascal Luc-Antoine Veilhan René Adam Didier Samuel Denis Castaing | 2007 | Annals of Surgery2007，，1： | 2 |
| 8 | Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy: A Model to Predict Long-term Survival显示文摘 | René Adam Valérie Delvart Gérard Pascal Adrian Valeanu Denis Castaing Daniel Azoulay Sylvie Giacchetti Bernard Paule Francis Kunstlinger Odile Ghémard Francis Levi Henri Bismuth | 2004 | Annals of Surgery2004，，4： | 2 |
| 9 | Tumor Marker Evolution: Comparison with Imaging for Assessment of Response to Chemotherapy in Patients with Colorectal Liver Metastases显示文摘 | Robbert J. Haas Dennis A. Wicherts Eduardo Flores Michel Ducreux Francis Lévi Bernard Paule Daniel Azoulay Denis Castaing Antoinette Lemoine René Adam | 2010 | Annals of Surgical Oncology2010，，4： | 2 |
| 10 | Simultaneous portal and hepatic vein embolization is better than portal embolization or ALPPS for hypertrophy of future liver remnant before major hepatectomy: A systematic review and network meta-analysis显示文摘Background:Post-hepatectomy liver failure(PHLF)is the Achilles’heel of hepatic resection for colorectal liver metastases.The most commonly used procedure to generate hypertrophy of the functional liver remnant(FLR)is portal vein embolization(PVE),which does not always lead to successful hypertrophy.Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)has been proposed to overcome the limitations of PVE.Liver venous deprivation(LVD),a technique that includes simultaneous portal and hepatic vein embolization,has also been proposed as an alternative to ALPPS.The present study aimed to conduct a systematic review as the first network meta-analysis to compare the efficacy,effectiveness,and safety of the three regenerative techniques.Data sources:A systematic search for literature was conducted using the electronic databases Embase,PubMed(MEDLINE),Google Scholar and Cochrane.Results:The time to operation was significantly shorter in the ALPPS cohort than in the PVE and LVD cohorts by 27 and 22 days,respectively.Intraoperative parameters of blood loss and the Pringle maneuver demonstrated non-significant differences between the PVE and LVD cohorts.There was evidence of a significantly higher FLR hypertrophy rate in the ALPPS cohort when compared to the PVE cohort,but non-significant differences were observed when compared to the LVD cohort.Notably,the LVD cohort demonstrated a significantly better FLR/body weight(BW)ratio compared to both the ALPPS and PVE cohorts.Both the PVE and LVD cohorts demonstrated significantly lower major morbidity rates compared to the ALPPS cohort.The LVD cohort also demonstrated a significantly lower 90-day mortality rate compared to both the PVE and ALPPS cohorts.Conclusions:LVD in adequately selected patients may induce adequate and profound FLR hypertrophy before major hepatectomy.Present evidence demonstrated significantly lower major morbidity and mortality rates in the LVD cohort than in the ALPPS and PVE cohorts. | Paschalis Gavriilidis Gabriele Marangoni Jawad Ahmad Daniel Azoulay | 2023 | Hepatobiliary & Pancreatic Diseases International2023，22，3： | 2 |
| 11 | Pulmonary Complications After Elective Liver Transplantation—Incidence, Risk Factors, and Outcome显示文摘 | Eric Levesque Emir Hoti Daniel Azoulay Isabelle Honore Bruno Guignard Eric Vibert Philippe Ichai Fadi Antoun Faouzi Saliba Didier Samuel | 2012 | Transplantation Journal2012，，5： | 1 |
| 12 | Split-liver Transplantation: The Paul Brousse Policy显示文摘 | Daniel Azoulay Ibrahim Astarcioglu Henri Bismuth Denis Castaing Pietro Majno Rene Adam Marc Johann | 1996 | Annals of Surgery1996，，6： | 1 |
| 13 | Medical community preferences concerning adult living related donor liver transplantation显示文摘 | Denis Castaing Daniel Azoulay Colette Danet Laurence Thoraval Catherine Tanguy Des Deserts Faouzi Saliba Didier Samuel René Adam | 2006 | Gastroenterologie Clinique et Biologique2006，，2： | 1 |
| 14 | Salvage transjugular intrahepatic portosystemic shunt for uncontrolled variceal bleeding in patients with decompensated cirrhosis显示文摘 | Daniel Azoulay Denis Castaing Pietro Majno Faouzi Saliba Philippe Icha?? Allaoua Smail Valérie Delvart Monzer Danaoui Didier Samuel Henri Bismuth | 2001 | Journal of Hepatology2001，，5： | 1 |
| 15 | Assessment of risk for non-hepatic surgery in cirrhotic patients显示文摘 | Prashant Bhangui Alexis Laurent Roland Amathieu Daniel Azoulay | 2012 | Journal of Hepatology2012，，： | 1 |
| 16 | Major Hepatectomy for Hilar Cholangiocarcinoma Type 3 and 4: Prognostic Factors and Longterm Outcomes显示文摘 | Olivier Baton Daniel Azoulay Delvart V. René Adam Denis Castaing | 2007 | Journal of the American College of Surgeons2007，，2： | 1 |
| 17 | Caval Inflow to the Graft for Liver Transplantation in Patients With Diffuse Portal Vein Thrombosis: A 12-Year Experience显示文摘 | Prashant Bhangui Chetana Lim Chady Salloum Paola Andreani Mylene Sebbagh Emir Hoti Philippe Ichai Faouzi Saliba Rene Adam Denis Castaing Daniel Azoulay | 2011 | Annals of Surgery2011，，6： | 1 |
| 18 | Liver Retransplantation: A Model for Determining Long-Term Survival显示文摘 | Marcelo M. Linhares Daniel Azoulay Délcio Matos Adauto Castelo-Filho Tarcísio Trivi?o Alberto Goldenberg Denis Castaing René Adam Valerie Délvart Phillipe Ichai Fauze Saliba Antoine Lemoine Didier Samuel Henry Bismuth | 2006 | Transplantation2006，，7： | 1 |
| 19 | Resection or Transplantation for Early Hepatocellular Carcinoma in a Cirrhotic Liver: Does Size Define the Best Oncological Strategy?显示文摘 | Rene Adam Prashant Bhangui Eric Vibert Daniel Azoulay Gilles Pelletier Jean-Charles Duclos-Vallée Didier Samuel Catherine Guettier Denis Castaing | 2012 | Annals of Surgery2012，，6： | 1 |
| 20 | Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy: A Model to Predict Long-term Survival显示文摘 | René Adam Valérie Delvart Gérard Pascal Adrian Valeanu Denis Castaing Daniel Azoulay Sylvie Giacchetti Bernard Paule Francis Kunstlinger Odile Ghémard Francis Levi Henri Bismuth | 2004 | Annals of Surgery2004，，4： | 1 |
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