|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle–mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response显示文摘 | Ivan Grskovic Anna Kutsch Christian Frie Gergely Groma Jacek Stermann Ursula Schl?tzer‐Schrehardt Anja Niehoff Stephen E Moss Sabrina Rosenbaum Ernst P?schl Markus Chmielewski Gunter Rappl Hinrich Abken John F Bateman Kathryn SE Cheah Mats Paulsson Bent B | 2012 | J Bone Miner Res2012,,11: | 1 |
| 2 | Myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis is chronic/relapsing in perforin knockout mice显示文摘 | Ursula M Karl F Spanaus KS | 1997 | Immunology1997,27,: | 1 |
| 3 | Biodeinking of flexographic inks by fungal laccases using synthetic and natural mediators显示文摘 | Ursula F Alicia P Susana C | 2012 | Biochemical Engineering Journal2012,67,: | 1 |
| 4 | Activation of the inflammasome by amorphous silica and TiO<sub>2</sub> nanoparticles in murine dendritic cells显示文摘 | Meike Winter Hans-Dietmar Beer Veit Hornung Ursula Kr?mer Roel P. F. Schins Irmgard F?rster | 2011 | Nanotoxicology2011,,3: | 1 |
| 5 | Invasive candidia- sis:comparison of management choices by infectious disease and critical care specialists 显示文摘 | PhilippeE Thierry C Ursula F | 2005 | Intensive Care Med2005,31,11: | 1 |
| 6 | Structural and biological characteristics of reoviruses isolated from muscovy ducks (Cairina moschata)显示文摘 | URSULA Heffels-redmann MULLER H KALETA E F | 1992 | Avian Pathology1992,21,: | 1 |
| 7 | Genome of a novel circovirus of starlings, amplified by multiply primed rolling-circle amplification 显示文摘 | Reimar J Daniel F L Ursula H | 2006 | Journal of General Virology2006,87,: | 1 |
| 8 | Oxygen free radical mediated injury tocultured rat hepatocytes during cold incubation in preservation solution显示文摘 | Ursula R Irith R Anke F | 1997 | Hepatology1997,26,: | 1 |
| 9 | Oxygen free radical mediated injury to cultured rat hepatocytes during cold incubation in preservation solution显示文摘 | Irith R Anke F | 1997 | Hepatology1997,26,: | 1 |
| 10 | Structural and biological characteristics of reoviruses isolated from muscovy ducks (Cairina moschata)显示文摘 | Ursula Heffels-redmann H Muller E F Kaleta | 1992 | Avian Pathology1992,21,: | 1 |
| 11 | A system dynamics model for the screening-level long-term assessment of human health risks at contaminated sites显示文摘 | URSULA S MCKNIGHT M F | 2012 | Environmental Modelling and Software2012,116,: | 1 |
| 12 | Compounds Isolated from Crataegus显示文摘 | Ursula K F | 1955 | Arzneimittel-Forsch1955,5,: | 1 |
| 13 | Flow cytometric DNA-quatification of three-color immunophenotyped cells for subpopulation specific determination of aneuploidy and proliferation显示文摘 | Uta O Daniel F Ursula R | 2001 | Journal of Immunological Methods2001,253,: | 1 |
| 14 | High rate of complete histopathological response in hepatocellular carcinoma patients after combined transarterial chemoembolization and stereotactic body radiation therapy显示文摘BACKGROUND Liver transplantation(LT)presents a curative treatment option in patients with early stage hepatocellular carcinoma(HCC)who are not eligible for resection or ablation therapy.Due to a risk of up 30%for waitlist drop-out upon tumor progression,bridging therapies are used to halt tumor growth.Transarterial chemoembolization(TACE)and less commonly stereotactic body radiation therapy(SBRT)or a combination of TACE and SBRT,are used as bridging therapies in LT.However,it remains unclear if one of those treatment options is superior.The analysis of explant livers after transplantation provides the unique opportunity to investigate treatment response by histopathology.AIM To analyze histopathological response to a combination of TACE and SBRT in HCC in comparison to TACE or SBRT alone.METHODS In this multicenter retrospective study,27 patients who received liver transplantation for HCC were analyzed.Patients received either TACE or SBRT alone,or a combination of TACE and SBRT as bridging therapy to liver transplantation.Liver explants of all patients who received at least one TACE and/or SBRT were analyzed for the presence of residual vital tumor tissue by histopathology to assess differences in treatment response to bridging therapies.Statistical analysis was performed using Fisher-Freeman-Halton exact test,Kruskal-Wallis and Mann-Whitney-U tests.RESULTS Fourteen patients received TACE only,four patients SBRT only,and nine patients a combination therapy of TACE and SBRT.There were no significant differences between groups regarding age,sex,etiology of underlying liver disease or number and size of tumor lesions.Strikingly,analysis of liver explants revealed that almost all patients in the TACE and SBRT combination group(8/9,89%)showed no residual vital tumor tissue by histopathology,whereas TACE or SBRT alone resulted in significantly lower rates of complete histopathological response(0/14,0%and 1/4,25%,respectively,P value<0.001).CONCLUSION Our data suggests that a combination of TACE and SBRT increases the rate of complete histopathological response compared to TACE or SBRT alone in bridging to liver transplantation. | Ulrike Bauer Sabine Gerum Falk Roeder Stefan Münch Stephanie E Combs Alexander B Philipp Enrico N De Toni Martha M Kirstein Arndt Vogel Carolin Mogler Bernhard Haller Jens Neumann Rickmer F Braren Marcus R Makowski Philipp Paprottka Markus Guba Fabian Geisler Roland M Schmid Andreas Umgelter Ursula Ehmer | 2021 | World Journal of Gastroenterology2021,27,24: | 1 |
| 15 | Pattern and dynamics of the ground vegetation in south Swedish Carpinus betulus forests:importance of soil chemistry and management显示文摘 | JBRG B URSULA F G GERMUND T | 1997 | Ecography1997,20,: | 1 |
| 16 | Invasive candidiasis:comparison of management choices by infectious disease and critical care specialists显示文摘 | Philippe E Thierry C Ursula F | 2005 | Intensive Care Med2005,31,11: | 1 |
| 17 | Growth of ectomycorrhizal mycelia and composition of soil microbial communities in oak forest soils along a nitrogen deposition gradient显示文摘 | Lars O N Erland B Ursula F G | 2007 | Ecosystem Ecology2007,153,: | 1 |
| 18 | Effect of H2 admixture on the adsorption of NO,NO2 and propane at Ag/Al2O3 catalyst as examined by in situ FTIR显示文摘 | Ursula B Manfred R Rolf F | 2005 | Applied Catalysis B:Environmental2005,55,3: | 1 |
| 19 | Root colonisation by arbuscular mycorrhizal, fine endophytic and dark septate fungi across a pH gradient in acid beech forests显示文摘 | Postma W M Olsson P A Ursula F G | 2007 | Soil Biology & Biochemistry2007,39,: | 1 |
| 20 | Pathways leading to apoptotic neurodegeneration following trauma to the developing rat brain显示文摘 | Ursula F M Marco S Stefanie P | 2002 | Neurobiology of Disease2002,11,: | 1 |