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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Bladder pheochromocytoma:a 3-year follow-up after transurethral resection(TURB)显示文摘 | Baima C Casetta G Vella R | | 0，，： | 1 |
| 3 | Bladder pheochromocytoma: a 3-year follow-up after transurethral resection (TURB)显示文摘 | Baima C Casetta G Vella R | 2000 | Urol Int2000，65，3： | 1 |
| 4 | Implementation of beta-blockade in elderly heart failure patients: role of the nurse specialist 显示文摘 | Mariani M Vella G Bianchi C | 2008 | Eur J Cardiovasc Nur2008，7，3： | 1 |
| 5 | Pathophysiology and clinical aspects of urinary lithiasis 显示文摘 | Vella M Karydi M Coraci G | 2007 | Urol Int2007，79，1： | 1 |
| 6 | Modeling of a TiO2 - coated quartz wool packed bed photocatalytic reactor 显示文摘 | VELLA G IMOBERDORF G E SCLAFANI A | 2010 | Applied Catalysis B: Environmental2010，，96： | 1 |
| 7 | Economic factors affecting the number of engineering graduates in Australia显示文摘 | LEWIS P E T Vella F G M | 1985 | Australian Economic Papers1985，24，44： | 1 |
| 8 | Economic Vul- nerability and Resilience: Concepts and Measurements显示文摘 | Briguglio L Cordina G Farrugia N Vella S | 2009 | Oxford Development Studies2009，37，3： | 1 |
| 9 | Enhanced replication of M-tropic HIV-1 strains in Herpesvirus saimiri immortalised T-cells which express CCR5显示文摘 | Zheng NN Vella G | 1999 | J Virol Meth1999，79，： | 1 |
| 10 | Overview of the MNA:its his-tory and challenges显示文摘 | Vellas B Villars H Abellan G | 2006 | J Nutr Health Aging2006，10，46： | 1 |
| 11 | DeltaNp73alpha inhibits PTEN expression in thyroid cancer cells显示文摘 | Vella V Puppin C Damante G | 2009 | Int J Cancer2009，124，11： | 1 |
| 12 | Biadder pheochromocytoma: a 3-year follow-up after transurethral resection ( TURB ) 显示文摘 | Baima C Casetta G Vella R | 2000 | Urol Int2000，65，： | 1 |
| 13 | A novel autecreine loop invoMng IGF2 and the insulin receptor isoformA stimulates growth of thyroid cancer显示文摘 | Vella V Pandini G Sciacca L | 2002 | J Clin Endocrinol Metab2002，87，1： | 1 |
| 14 | Chronic allograft nephropathy and peritubular capillary C4d deposition in protocol renal allograft biopsies显示文摘 | Ghirardo G Della Vella M Benetti E Vidal E Centi S Murer L | 2011 | Pediatric Nephrology2011，26，： | 1 |
| 15 | Case of multiple myeloma mimicking an infectious disease with fever,intrahepatic cholestasis,renal failure,and pulmonary insufficiency显示文摘 | Vella FS Simone B Giannelli G | | 0，，： | 1 |
| 16 | The Flaveria bidentis β-Carbonic anhydrase gene family encodes cytosolic and chloroplastic isoforms demonstrating distinct organ-specific expression patterns显示文摘 | Sasha G T Sandra K T Nicole Vella | 2007 | Plant Physiology2007，144，6： | 1 |
| 17 | D - lactate acidosis :pathologic consequence of saprophytism显示文摘 | Vella A Farragia G | 1998 | Mayo Clin Proc1998，73，： | 1 |
| 18 | Determination of postmortem interval from old skeletal remains by image analysis of luminol test resuhs显示文摘 | Imtrona F Jr Di Vella G Campobasso CP | 1999 | J Forensic Sci1999，44，3： | 1 |
| 19 | Sex determination by discriminant analysis of calcanei measurements显示文摘 | Introna F Jr Di Vella G Campobasso CP | 1997 | J Forensic Sci1997，42，4： | 1 |
| 20 | D-lactate acidosis:pathologic consequence of saprophytism 显示文摘 | Vella A Farragia G | 1998 | Mayo Clin Proc1998，73，45： | 1 |
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