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| 1 | Diagnosis of focal liver lesions with deep learning-based multichannel analysis of hepatocyte-specific contrast-enhanced magnetic resonance imaging显示文摘BACKGROUND The nature of input data is an essential factor when training neural networks.Research concerning magnetic resonance imaging(MRI)-based diagnosis of liver tumors using deep learning has been rapidly advancing.Still,evidence to support the utilization of multi-dimensional and multi-parametric image data is lacking.Due to higher information content,three-dimensional input should presumably result in higher classification precision.Also,the differentiation between focal liver lesions(FLLs)can only be plausible with simultaneous analysis of multisequence MRI images.AIM To compare diagnostic efficiency of two-dimensional(2D)and three-dimensional(3D)-densely connected convolutional neural networks(DenseNet)for FLLs on multi-sequence MRI.METHODS We retrospectively collected T2-weighted,gadoxetate disodium-enhanced arterial phase,portal venous phase,and hepatobiliary phase MRI scans from patients with focal nodular hyperplasia(FNH),hepatocellular carcinomas(HCC)or liver metastases(MET).Our search identified 71 FNH,69 HCC and 76 MET.After volume registration,the same three most representative axial slices from all sequences were combined into four-channel images to train the 2D-DenseNet264 network.Identical bounding boxes were selected on all scans and stacked into 4D volumes to train the 3D-DenseNet264 model.The test set consisted of 10-10-10 tumors.The performance of the models was compared using area under the receiver operating characteristic curve(AUROC),specificity,sensitivity,positive predictive values(PPV),negative predictive values(NPV),and f1 scores.RESULTS The average AUC value of the 2D model(0.98)was slightly higher than that of the 3D model(0.94).Mean PPV,sensitivity,NPV,specificity and f1 scores(0.94,0.93,0.97,0.97,and 0.93)of the 2D model were also superior to metrics of the 3D model(0.84,0.83,0.92,0.92,and 0.83).The classification metrics of FNH were 0.91,1.00,1.00,0.95,and 0.95 using the 2D and 0.90,0.90,0.95,0.95,and 0.90 using the 3D models.The 2D and 3D networks'performance in the diagnosis of HCC were 1.00,0.80,0.91,1.00,and 0.89 and 0.88,0.70,0.86,0.95,and 0.78,respectively;while the evaluation of MET lesions resulted in 0.91,1.00,1.00,0.95,and 0.95 and 0.75,0.90,0.94,0.85,and 0.82 using the 2D and 3D networks,respectively.CONCLUSION Both 2D and 3D-DenseNets can differentiate FNH,HCC and MET with good accuracy when trained on hepatocyte-specific contrast-enhanced multi-sequence MRI volumes. | Róbert Stollmayer Bettina K Budai Ambrus Tóth IldikóKalina Erika Hartmann Péter Szoldán Viktor Bérczi Pál Maurovich-Horvat Pál N Kaposi | 2021 | World Journal of Gastroenterology2021，27，35： | 6 |
| 2 | Instability of magnetic fluid in a narrow gap between plates显示文摘 | VIKTOR P LUTZ T | 2005 | Journal of Magnetism and Magnetic Materials2005，，289： | 1 |
| 3 | Effects of the available nitrogen on the photosynthetic activity and xan-thophyll cycle pool of maize in field显示文摘 | Viktor R T Mszros I Veres S | 2002 | J Plant Physiol2002，159，： | 1 |
| 4 | Genetic variability in tolerance to cadmium and accumulation of heavy metals in pea(Pisum sativum L)显示文摘 | Aanrei A B Vera I S Viktor E T et a1 | 2003 | Euphytica2003，131，： | 1 |
| 5 | Male-biased sex ratios and vitellogenin induction in Zebrafish exposed to effluent Water from a Swedish pulp mill显示文摘 | Om S Svenson A Viktor T | 2006 | Archives of Environmental Contamination and Toxicology2006，51，： | 1 |
| 6 | A Scalable and Modular Architecture for High-performance Packet Classification显示文摘 | Ganegedara T Jiang Weirong Viktor K | 2014 | IEEE Transactions on Parallel and Dis- tributed Systems2014，25，5： | 1 |
| 7 | Modelling constructed wetland treatment system performance显示文摘 | Volodymyr T Sirajuddin A Viktor P | 2007 | Ecological Modelling2007，205，34： | 1 |
| 8 | Effects of the available nitrogen on the photosynthetic activity and xanthophyll cycle pool of maize in field 显示文摘 | Viktor R T Ilona M Szilvia V | 2002 | Journal of Plant Physiology2002，159，6： | 1 |
| 9 | A handware architecture for real-time video segmentation utilizing memory reduction techniques显示文摘 | Jiang H T Hakan Ardo Viktor Owall | 2009 | IEEE Transactions on Circuits and Systems for Video Technology2009，19，2： | 1 |
| 10 | Male-biased sex ratios and vitellogenin induction in zebra fish exposed to effluent water from a Swedish pulp mill显示文摘 | Orn S Svenson A Viktor T | 2006 | Archives of Environmental Contamination and Toxicology2006，51，3： | 1 |
| 11 | Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study显示文摘 | Linda Wittkop Huldrych F Günthard Frank de Wolf David Dunn Alessandro Cozzi-Lepri Andrea de Luca Claudia Kücherer Niels Obel Viktor von Wyl Bernard Masquelier Christoph Stephan Carlo Torti Andrea Antinori Federico García Ali Judd Kholoud Porter Rodolphe T | 2011 | The Lancet Infectious Diseases2011，，5： | 1 |
| 12 | Male-biased sex ratios and vitellogenin induction in Zebrafish exposed to effluent water from a Swedish pulpmill 显示文摘 | Orn S Svenson A Viktor T | 2006 | Archives of Environmental Contamination and Toxicology2006，51，： | 1 |
| 13 | Structure and properties ofB4C-SiCcomposites显示文摘 | Yurii G T Viktor F B Emmanuil V P | 2005 | Powder Metallurgyand Metal Ceramics2005，44，34： | 1 |
| 14 | Thermogravimetric investigations of modified iron oe pellets for hydrogen storage and purification:The first charge and discharge cycle显示文摘 | Viktor H Rudolf V Markus T | 2007 | Industrial and Engineering Chemistry Research2007，46，26： | 1 |
| 15 | Harmonized test procedure for steel fibre - reinforced concrete 显示文摘 | Marti P Pfyl T S Viktor U T | 1999 | ACI Materials Journal1999，96，6： | 1 |
| 16 | Modelling constructed wetland treatment system performance显示文摘 | Volodymyr T Sirajuddin A Viktor P | | 0，，3： | 1 |
| 17 | Tri-and Tetra-chloroveratrole,Metabolires Produced by Bacterial O-methylation of Tri-and Tetra-chloroguaiacol:an Assessment of Their Bioconcentration Potential and Their Effects on Fish Reproduction显示文摘 | Allard A-S Reiland S Remberger M T(a)rnholm A Viktor T Landner L | 1984 | Can J Fish Aquat Sci1984，41，： | 1 |
| 18 | Improving ecosystem services in farmlands:beginning of a long-term ecological study with restored flower-rich grasslands显示文摘Biodiversity declines in an unprecedented way,mostly due to land use change.Restoration interventions proved to be one of the most effective tools to halt the decline,especially in ecosystems such as agricultural fields.Evidence-based,locally adapted recommendations on grassland restoration,however,are often missing,so we present a novel approach for such interventions that can be implemented anywhere and that are based on scientific rigor.In a recently started long-term field ecological study,we established 0.5 ha wildflower parcels,using a diverse local seed mixture of 32 insect-visited plant species in Central European agricultural landscapes in 2020.Our focus is on the landscape-scale effects of this ecological intensification on ecosystem services such as crop yield,pollination and pest control,and the long-term monitoring of the successional processes.The aim is to showcase an effective restoration protocol that could serve as a model for future farm management,and provide much-needed evidence for policy on landscape ecological restoration of international relevance. | András Báldi Raoul Pellaton Áron Domonkos Bihaly Viktor Szigeti Eszter Lellei-Kovács András Máté Miklós Sárospataki Zoltán Soltész LászlóSomay AnikóKovács-Hostyánszki | 2022 | Ecosystem Health and Sustainability2022，8，1： | 0 |
| 19 | Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic显示文摘Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were reported.The study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines.Methods We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke centres.Patients with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,codes.The 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May 2020.The prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal variation.Findings There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative drop.Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this tertile.Interpretation There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic.These findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction. | Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sugimura Masaaki Uno Yohei Takenobu Yuji Matsumaru Satoshi Yamada Ryuhei Kono Takuya Kanamaru Masafumi Morimoto Junichi Iida Vasu Saini Dileep Yavagal Saif Bushnaq Wenguo Huang Italo Linfante Jawad Kirmani David S Liebeskind Viktor Szeder Ruchir Shah Thomas G Devlin Lee Birnbaum Jun Luo Anchalee Churojana Hesham E Masoud Carlos Ynigo Lopez Brendan Steinfort Alice Ma Ameer E Hassan Amal Al Hashmi Mollie McDermott Maxim Mokin Alex Chebl Odysseas Kargiotis Georgios Tsivgoulis Jane G Morris Clifford J Eskey Jesse Thon Leticia Rebello Dorothea Altschul Oriana Cornett Varsha Singh Jeyaraj Pandian Anirudh Kulkarni Pablo M Lavados Veronica V Olavarria Kenichi Todo Yuki Yamamoto Gisele Sampaio Silva Serdar Geyik Jasmine Johann Sumeet Multani Artem Kaliaev Kazutaka Sonoda Hiroyuki Hashimoto Adel Alhazzani David Y Chung Stephan A Mayer Johanna T Fifi Michael D Hill Hao Zhang Zhengzhou Yuan Xianjin Shang Alicia C Castonguay Rishi Gupta Tudor G Jovin Jean Raymond Osama O Zaidat Raul G Nogueira SVIN COVID-19 Registry,the Middle East North Africa Stroke and Interventional Neurotherapies Organization(MENA-SINO),Japanese Society of Vascular and Interventional Neurology Society(JVIN) | 2021 | Stroke & Vascular Neurology2021，6，4： | 0 |
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