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| 1 | RNA N^6-methyladenosine modification in cancers: current status and perspectives显示文摘 | Xiaolan Deng Rui Su Hengyou Weng Huilin Huang Zejuan Li Jianjun Chen | 2018 | Cell Research2018，28，5： | 55 |
| 2 | N-methyl-D-aspartic acid receptor 1 (NMDAR1) aggravates secondary inflammatory damage induced by hemin-NLRP3 pathway after intracerebral hemorrhage显示文摘 | Xun Weng Yan Tan Xiang Chu Xiao-Feng Wu Rui Liu Yue Tian Lin Li Feng Guo Qing Ouyang Lei Li | 2015 | Chinese Journal of Traumatology2015，18，5： | 12 |
| 3 | Promoting effect of microwave irradiation on CeO2-TiO2 catalyst for selective catalytic reduction of NO by NH3显示文摘In this work we prepared several CeO2-TiO2 catalysts for the NH3-SCR reactionusing co-precipitation with assistance of microwave irradiation.The catalytic NH3-SCR activities over CeO2-TiO2 catalysts at low temperatures are largely enhanced by the treatment of microwave irradiation,the operation temperature window is also broadened.For better understanding the promotion mechanism,the catalyst prepared by conventional co-precipitation with and without microwave irradiation treatment was characterized with H2-TPR,NH3-TPD,XPS,XRD and BET.Microwave irradiation treatment accelerates the crystallite rate of CeO2-TiO2 catalysts,and greatly enlarges their surface area by adjusting their microstructures.The resistance to SO2 and H2O is also improved via regulating the hierarchical pore structure by the microwave irradiation.Microwave irradiation treatment can also improve the redox property and increase the acid sites over the catalyst surfaces.The result of in situ DRIFTS suggests that the microwave irradiation treatment generates more Br?nsted acid sites on CeO2-TiO2-2 h catalyst,helpful in SCR reactions.XPS results show that after microwave irradiation on the CeO2-TiO2 catalysts,the surface demonstrates an elevated concentration of chemisorbed oxygen,consequently leading to better oxidation of NO to NO2.Additionally,the molar ratio of Ce3+/Ce4+has been elevated after being treated by microwave irradiation,a vital factor in enhancing the NH3-SCR activities. | Jie Cheng Liyun Song Rui Wu Shining Li Yanming Sun Hongtai Zhu Wenge Qiu Hong He | 2020 | Journal of Rare Earths2020，38，1： | 11 |
| 4 | Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice显示文摘Hedyotis hedyotidea 为自体免疫的疾病的治疗在繁体中文药被使用了。然而,为效果位于下面的机制仍然保持未知。我们以前证明在从 H hedyotidea 提取的 11 混合物之中, betulin 在 T 房间激活上生产了最强壮的镇压效果。这里,我们在位于效果下面的老鼠和机制对尖锐自体免疫的肝炎检验了 betulin 的 hepatoprotective 效果。刚孤立的老鼠 splenocytes 与 concanavalin A 被刺激(反对 A, 5 g/mL ) 面对 betulin,房间增长与 CSFE 冲淡被估计试金。老鼠与 betulin 被注射(10, 20 mg ? | Yong-qin ZHOU Xiu-fang WENG Rui DOU Xiao-sheng TAN Tian-tian ZHANG Jin-bo FANG Xiong-wen WU | 2017 | Acta Pharmacologica Sinica2017，38，2： | 10 |
| 5 | Controlled pore size of Pt/KIT-6 used for propane total oxidation显示文摘Mesoporous silica KIT-6 with different pore sizes was controllably synthesized by hydrothermal methods. The same contents of Pt were loaded on KIT-6 supports to apply for propane total oxidation. Low-angle X-ray diffraction(XRD), nitrogen adsorption-desorption, CO chemisorption and transmission electron microscopy(TEM) were carried out to investigate the physicochemical properties of the catalysts. The results reveal that different pore sizes of KIT-6 supports could affect the Pt particle sizes on KIT-6. The mesopores on KIT-6-80 and KIT-6-130 effectively confine the size of the inside Pt nanoparticles during calcining. Pt/KIT-6-80 with the appropriate pore size as well as the Pt particle size exhibits the best catalytic performance with T_(50)(the temperature at which hydrocarbon(HC) conversion reaches 50%) of only 237 ℃. However, Pt particles prefer dispersing on the external surface of KIT-6-40 due to those too small pores. | Yu-Sheng Chen Yi-Dan Cao Rui Ran Xiao-Dong Wu Duan Weng | 2018 | Rare Metals2018，37，2： | 5 |
| 6 | Microstructure and oxygen storage capacity of Sr-modified Pt/CeO_2-ZrO_2 catalysts | Rui Ran a,Jun Fan b,Duan Weng a,a State Key Lab of New Ceramic and Fine Processing,Department of Materials Science and Engineering,Tsinghua University,Beijing 100084,China b The Administrative Centre for China’s Agenda 21,Beijing 100038,China | 2012 | Progress in Natural Science:Materials International2012，22，1： | 5 |
| 7 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
| 8 | A novel insight into enhanced propane combustion performance on PtUSY catalyst显示文摘Platinum was supported on c-Al_2O_3 and ultrastable Y zeolite(USY) by an incipient wetness impregnation method. The catalysts were characterized by nitrogen physisorption, transmission electron microscopy(TEM),CO/C_3H_8 isothermal oxidations, NH_3 temperature-programmed desorption(NH_3–TPD) and infrared(IR) spectroscopy of adsorbed probe molecules(CO, C_3H_8 and C_3H_8+ O_2). Compared with Pt/Al_2O_3, Pt USY catalyst shows obviously higher activity for the combustion of propane. After estimating the size effect of Pt particles and propane adsorption capacity of USY, the excellent activity of Pt USY is also attributed to the strong interactions between the precious metal and the acidic zeolite. It inhibits the oxidation of Pt in an oxygen-rich atmosphere at high temperatures, which facilitate the initial oxidation step involving the C–H bond activation on metallic Pt as reflected by in situ diffuse reflectance infrared Fouriertransformed(DRIFT) spectra. | Hui Luo Xiao-Dong Wu Duan Weng Shuang Liu Rui Ran | 2017 | Rare Metals2017，36，1： | 5 |
| 9 | Propane dehydrogenation catalyzed by in-situ partially reduced zinc cations confined in zeolites显示文摘Propane dehydrogenation(PDH), employing Pt-or Cr-based catalysts, represents an emerging industrial route for propylene production. Due to the scarcity of platinum and the toxicity of chromium, alternative PDH catalysts are being pursued. Herein, we report the construction of Zn-containing zeolite catalysts,namely Zn@S-1, for PDH reaction. Well-isolated zinc cations are successfully trapped and stabilized by the Si-OH groups in S-1 zeolites via in-situ hydrothermal synthesis. The as-prepared Zn@S-1 catalysts exhibit good dehydrogenation activity, high propylene selectivity, and regeneration capability in PDH reaction under employed conditions. The in-situ partial reduction of zinc species is observed and the partially reduced zinc cations are definitely identified as the active sites for PDH reaction. | Linjun Xie Rui Wang Yuchao Chai Xuefei Weng Naijia Guan Landong Li | 2021 | Journal of Energy Chemistry2021，30，12： | 4 |
| 10 | Topological Nodal States in Circuit Lattice显示文摘Te search for artifcial structure with tunable topological properties is an interesting research direction of today’s topological physics.Here,we introduce a scheme to realize topological nodal states with a three-dimensional periodic inductor-capacitor(LC)circuit lattice,where the topological nodal line state and Weyl state can be achieved by tuning the parameters of inductors and capacitors.A tight-binding-like model is derived to analyze the topological properties of the LC circuit lattice.Te key characters of the topological states,such as the drumhead-like surface bands for nodal line state and the Fermi arc-like surface bands for Weyl state,are found in these systems.We also show that the Weyl points are stable with the fabrication errors of electric devices. | Kaifa Luo Rui Yu Hongming Weng | 2018 | Research2018，，1： | 4 |
| 11 | Unsupervised noise-robust feature extraction for aerial image classification显示文摘The rich data provided by satellites and unmanned aerial vehicles bring opportunities to directly model aerial image features by extracting their spatial and structural patterns.Although convolutional autoencoders(CAEs)have been attained a remarkable performance in ideal aerial image feature extraction,they are still challenging to extract information from noisy images which are generated from capture and transmission.In this paper,a novel CAE-based noise-robust unsupervised learning method is proposed for extracting high-level features accurately from aerial images and mitigating the effect of noise.Different from conventional CAEs,the proposed method introduces the noise-robust module between the encoder and the decoder.Besides,several pooling layers in CAEs are replaced by convolutional layers with stride=2.The performance of feature extraction is evaluated by the prediction accuracy and the accuracy loss in image classification experiments.A 5-classes aerial optical scene and a 9-classes hyperspectral image(HSI)data set are utilized for optical image and HSI feature extraction,respectively.Highlevel features extracted from aerial images are utilized for image classification by a linear support vector machine(SVM)classifier.Experimental results indicate that the proposed method improves the classification accuracy for noisy images(Gaussian noise 2Dσ=0.1,3Dσ=60)in both optical images(2D 87.5%)and HSIs(3D 85.6%)compared with the traditional CAE(2D 78.6%,3D 84.2%).The accuracy loss in classification experiments increases with the increment of noise.Compared with the traditional CAE(2D 15.7%,3D 11.8%),the proposed method shows the lower classification accuracy loss in experiments(2D 0.3%,3D 6.3%).The proposed unsupervised noise-robust feature extraction method attains desirable classification accuracy in ideal input and enhances the feature extraction capability from noisy input. | LIANG Ye LU Shuai WENG Rui HAN ChengZhe LIU Ming | 2020 | Science China(Technological Sciences)2020，63，8： | 3 |
| 12 | Topological nodal line semimetals predicted from first-principles calculations显示文摘拓扑的半金属是量物质的最新发现的状态,它从绝缘体扩大了拓扑的状态的概念到金属并且在最近的年里吸引了大研究兴趣。一般来说,有三种拓扑的半金属,也就是迪拉克半金属, Weyl 半金属,和节的线半金属。节的线半金属能为另外的拓扑的状态被看作先锋状态。例如,从如此的节的线开始说,节的线结构可能演变为 Weyl 点,把点变换成迪拉克,或由介绍联合的纺纱轨道(SOC ) 或集体术语成为拓扑的绝缘体。在这篇评论论文,我们介绍显示出节的线半金属状态的理论材料,包括所有碳 Mackay-Terrones 水晶( MTC ), anti-perovskite Cu 3 PdN ,压的黑磷,和材料的帽子3家庭,并且我们在场为获得物质的如此的新奇状态的设计原则。 | Rui Yu Zhong Fang Xi Dai Hongming Weng | 2017 | Frontiers of physics2017，12，3： | 3 |
| 13 | Effects of baria on propane oxidation activity of Pd/Al_2O_3 catalyst:Pd–BaO interaction and reaction routes显示文摘The BaO-modified Pd/Al2O3exhibits much better catalytic activity than Pd/Al2O3for C3H8 oxidation both before and after the hydrothermal aging treatment. Further studies ascribe its good activity to the influence of BaO species on the physicochemical characteristics of the catalyst and the reaction routes. Firstly, the BaO species inhibits the phase transformation of alumina, resulting in higher surface area of the catalysts and hereby a better dispersion of Pd. Secondly, the basic nature and electron-withdrawing effect of barium oxide maintain palladium at high oxidation state, which leads to a higher PdO content on surface of the BaO-modified catalyst. Finally, the formation/decomposition of carbonate/bicarbonate species can be promoted by the addition of BaO, which provide extra reaction routes and are important for the deep oxidation of C3H8. | Min Li Xiaodong Wu Shuang Liu Jie Wan Rui Ran Duan Weng | 2014 | Progress in Natural Science:Materials International2014，24，3： | 3 |
| 14 | ZrO_2-supported α-MnO_2:Improving low-temperature activity and stability for catalytic oxidation of methane显示文摘The single phaseα-Mn O_2and in-situ supportedα-Mn O_2/Zr O_2with different ratios of Mn/Zr were synthesized by one-pot hydrothermal method.They showed superior activity for catalytic oxidation of methane and even better than that of 1%Pt/Al_2O_3.The T_(50)of Mn O_2/Zr O_2catalysts with different ratios of Mn/Zr were located in the range of 315–335°C at a WHSV of 90 L g^(-1)h^(-1),whereas that of Pt/Al_2O_3was 380°C.After sulfur ageing,the Mn O_2/Zr O_2catalysts with Mn/Zr ratio of 2:1(2Mn O_2/1Zr O_2)and 1:1(1Mn O_2/1Zr O_2)exhibited satisfying sulfur resistance in comparison to the pure Mn O_2.The 2Mn O_2/1Zr O_2catalyst also showed acceptable catalytic stability,and the addition of 10 vol%CO_2had no obvious negative effect on its stability,whereas the addition of2.6 vol%H_2O caused slight but reversible decreasing methane oxidative activity. | Jingbo Jia Rui Ran Ruiqi Guo Xiaodong Wu Duan Weng | 2018 | Progress in Natural Science:Materials International2018，28，3： | 2 |
| 15 | Improved activity and durability of Rh-based three-way catalyst under diverse aging atmospheres by ZrO2 support显示文摘The catalytic activity and durability of Rh/ZrO_2 catalyst were investigated compared with Rh/Al_2O_3 catalyst under diverse aging atmospheres, including lean, rich and lean–rich cyclic aging atmospheres, to simulate the real working conditions of three-way catalyst.Oxidation states and microstructures of rhodium species were investigated to correlate with the catalytic performance of the catalysts. The catalytic performance and durability of the Rh catalyst under diverse aging atmospheres were drastically enhanced by ZrO_2 support. ZrO_2 support was confirmed to be able to effectively inhibit rhodium sintering even under diverse aging conditions. It can also successfully keep Rh species in an active low-valence state on the surface of the catalyst. The superiority of ZrO_2 support compared to Al_2O_3 was verified by the Rh-based monolith catalyst. | Yidan Cao Rui Ran Xiaodong Wu Baohuai Zhao Duan Weng | 2017 | Journal of Environmental Sciences2017，29，2： | 2 |
| 16 | B Cell-mediated Humoral Immunity in Chronic Hepatitis B Infection显示文摘B cell-mediated humoral immunity plays a vital role in viral infections,including chronic hepatitis B virus(HBV)infection,which remains a critical global public health issue.Despite hepatitis B surface antigen-specific antibodies are essential to eliminate viral infections,the reduced immune functional capacity of B cells was identified,which was also correlated with chronic hepatitis B(CHB)progression.In addition to B cells,T follicular helper(Tfh)cells,which assist B cells to produce antibodies,might also be involved in the process of anti-HBVspecific antibody production.Here,we provide a comprehensive review of the role of various subsets of B cells and Tfh cells during CHB progression and discuss current novel treatment strategies aimed at restoring humoral immunity.Understanding the mechanism of dysregulated B cells and Tfh cells will facilitate the ultimate functional cure of CHB patients. | Yang Li Shengxia Yin Rahma Issa Xin Tong Guiyang Wang Juan Xia Rui Huang Guangmei Chen Dan Weng Chen Chen Chao Wu Yuxin Chen | 2021 | Journal of Clinical and Translational Hepatology2021，9，4： | 2 |
| 17 | Application of silica-alumina as hydrothermally stable supports for Pt catalysts for acid-assisted soot oxidation显示文摘In this work,silica-alumina mixed oxides with different SiO_(2)contents(5%and 30%)were adopted as acidic supports for platinum catalysts for soot oxidation.The obtained catalysts were hydrothermally aged in 10%H_(2)0/air at 750℃for 20 h.The catalysts were characterized by X-ray diffraction(XRD),N_(2)adsorption,inductively coupled plasma(ICP),CO chemisorption,NH3temperature-programmed desorption(TPD),infrared(IR)spectroscopy of CO adsorption,temperature-programmed oxidation(TPO)of NO,and TPD of NO_(x).The surface acidity of catalyst was positive correlated with the content of SiO_(2),which kept platinum in metallic and partially oxidized states in an oxidizing atmosphere.Compared with sulfation treatment on the alumina support,the application of SiO_(2)-Al_(2)O_(3)mixed oxides does not result in the coverage of Pt active sites and the prepared catalysts exhibit excellent activity for NO oxidation.They promote NOxpreferential adsorption on soot and decomposition of surface oxygenated compounds(SOCs)as the sulfated Pt/Al_(2)O_(3)catalyst does. | Shu-Ran Liu Shu-Ting Luo Xiao-Dong Wu Tao-Jin Wang Rui Ran Duan Weng Zhi-Chun Si Shuang Liu | 2023 | Rare Metals2023，42，5： | 2 |
| 18 | Overexpression of Purinergic P2X4 Receptors in Hippocampus Rescues Memory Impairment in Rats with Type 2 Diabetes显示文摘Purinergic receptors have been reported to be involved in brain disorders.In this study,we explored their roles and mechanisms underlying the memory impairment in rats with type 2 diabetes mellitus(T2 DM).T2 DM rats exhibited a worse performance in the T-maze and Morris water maze(MWM) than controls.Microglia positive for P2 X purinoceptor 4(P2 X4 R) in the hippocampus were reduced and activated microglia were increased in T2 DM rats.Long Amplicon PCR(LA-PCR) showed that DNA amplification of the p2 x4 r gene in the hippocampus was lower in T2 DM rats.Minocycline significantly reduced the number of activated microglia and the mean distance traveled by T2 DM rats in the MWM.Most importantly,P2 X4 R overexpression suppressed the activated microglia and rescued the memory impairment of T2 DM rats.Overall,T2 DM led to excessive activation of microglia in the hippocampus,partly through the DNA damagemediated downregulation of P2 X4 Rs,thus contributing to memory impairment. | Ping-An Zhang Qian Sun Yong-Chang Li Rui-Xia Weng Rui Wu Hong-Hong Zhang Guang-Yin Xu | 2020 | Neuroscience Bulletin2020，36，7： | 2 |
| 19 | Advanced nitrogen removal with simultaneous Anammox and denitrification in sequencing batch reactor显示文摘 | Rui Du Yongzhen Peng Shenbin Cao Chengcheng Wu Dongchen Weng Shuying Wang Jianzhong He | 2014 | Bioresource Technology2014，，： | 2 |
| 20 | Glycosylation of dentin matrix protein 1 is critical for fracture healing via promoting chondrogenesis显示文摘Fractures are frequently occurring diseases that endanger human health. Crucial to fracture healing is cartilage formation, which provides a bone-regeneration environment. Cartilage consists of both chondrocytes and extracellular matrix (ECM). The ECM of cartilage includes collagens and various types of proteoglycans (PGs), which play important roles in maintaining primary stability in fracture healing. The PG form of dentin matrix protein 1 (DMP1-PG) is involved in maintaining the health of articular cartilage and bone. Our previous data have shown that DMP1-PG is richly expressed in the cartilaginous calluses of fracture sites. However, the possible significant role of DMP1-PG in chondrogenesis and fracture healing is unknown. To further detect the potential role of DMP1-PG in fracture repair, we established a mouse fracture model by using a glycosylation site mutant DMP1 mouse (S89G-DMP1 mouse). Upon inspection, fewer cartilaginous calluses and down-regulated expression levels of chondrogenesis genes were observed in the fracture sites of S89G-DMP1 mice. Given the deficiency of DMP1-PG, the impaired IL-6/JAK/STAT signaling pathway was observed to affect the chondrogenesis of fracture healing. Overall, these results suggest that DMP1-PG is an indispensable proteoglycan in chondrogenesis during fracture healing. | Hui Xue Dike Tao Yuteng Weng Qiqi Fan Shuang Zhou Ruilin Zhang Han Zhang Rui Yue Xiaogang Wang Zuolin Wang Yao Sun | 2019 | Frontiers of Medicine2019，13，5： | 2 |
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