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| 1 | Erianin,a novel dibenzyl compound in Dendrobium extract,inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis显示文摘Ferroptosis,a novel form of programmed cell death,is characterized by iron-dependent lipid peroxidation and has been shown to be involved in multiple diseases,including cancer.Stimulating ferroptosis in cancer cells may be a potential strategy for cancer therapy.Therefore,ferroptosis-inducing drugs are attracting more attention for cancer treatment.Here,we showed that erianin,a natural product isolated from Dendrobium chrysotoxum Lindl,exerted its anticancer activity by inducing cell death and inhibiting cell migration in lung cancer cells.Subsequently,we demonstrated for the first time that erianin induced ferroptotic cell death in lung cancer cells,which was accompanied by ROS accumulation,lipid peroxidation,and GSH depletion.The ferroptosis inhibitors Fer-1 and Lip-1 but not Z-VAD-FMK,CQ,or necrostatin-1 rescued erianin-induced cell death,indicating that ferroptosis contributed to erianin-induced cell death.Furthermore,we demonstrated that Ca^(2+)/CaM signaling was a critical mediator of erianin-induced ferroptosis and that blockade of this signaling significantly rescued cell death induced by erianin treatment by suppressing ferroptosis.Taken together,our data suggest that the natural product erianin exerts its anticancer effects by inducing Ca^(2+)/CaMdependent ferroptosis and inhibiting cell migration,and erianin will hopefully serve as a prospective compound for lung cancer treatment. | Peng Chen Qibiao Wu Jiao Feng Lili Yan Yitian Sun Shuiping Liu Yu Xiang Mingming Zhang Ting Pan Xiaying Chen Ting Duan Lijuan Zhai Bingtao Zhai Wengang Wang Ruonan Zhang Bi Chen Xuemeng Han Yicong Li Liuxi Chen Ying Liu Xingxing Huang Ting Jin Wenzheng Zhang Hong Luo Xiaohui Chen Yongqiang Li Qiujie Li Guohua Li Qin Zhang Lvjia Zhuo Zuyi Yang Huifen Tang Tian Xie Xiaoping Ouyang Xinbing Sui | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 42 |
| 2 | State-of-the-art review of soft computing applications in underground excavations显示文摘Soft computing techniques are becoming even more popular and particularly amenable to model the complex behaviors of most geotechnical engineering systems since they have demonstrated superior predictive capacity,compared to the traditional methods.This paper presents an overview of some soft computing techniques as well as their applications in underground excavations.A case study is adopted to compare the predictive performances of soft computing techniques including eXtreme Gradient Boosting(XGBoost),Multivariate Adaptive Regression Splines(MARS),Artificial Neural Networks(ANN),and Support Vector Machine(SVM) in estimating the maximum lateral wall deflection induced by braced excavation.This study also discusses the merits and the limitations of some soft computing techniques,compared with the conventional approaches available. | Wengang Zhang Runhong Zhang Chongzhi Wu Anthony Teck Chee Goh Suzanne Lacasse Zhongqiang Liu Hanlong Liu | 2020 | Geoscience Frontiers2020，11，4： | 33 |
| 3 | Prediction of undrained shear strength using extreme gradient boosting and random forest based on Bayesian optimization显示文摘Accurate assessment of undrained shear strength(USS)for soft sensitive clays is a great concern in geotechnical engineering practice.This study applies novel data-driven extreme gradient boosting(XGBoost)and random forest(RF)ensemble learning methods for capturing the relationships between the USS and various basic soil parameters.Based on the soil data sets from TC304 database,a general approach is developed to predict the USS of soft clays using the two machine learning methods above,where five feature variables including the preconsolidation stress(PS),vertical effective stress(VES),liquid limit(LL),plastic limit(PL)and natural water content(W)are adopted.To reduce the dependence on the rule of thumb and inefficient brute-force search,the Bayesian optimization method is applied to determine the appropriate model hyper-parameters of both XGBoost and RF.The developed models are comprehensively compared with three comparison machine learning methods and two transformation models with respect to predictive accuracy and robustness under 5-fold cross-validation(CV).It is shown that XGBoost-based and RF-based methods outperform these approaches.Besides,the XGBoostbased model provides feature importance ranks,which makes it a promising tool in the prediction of geotechnical parameters and enhances the interpretability of model. | Wengang Zhang Chongzhi Wu Haiyi Zhong Yongqin Li Lin Wang | 2021 | Geoscience Frontiers2021，12，1： | 33 |
| 4 | Estimation of diaphragm wall deflections for deep braced excavation in anisotropic clays using ensemble learning显示文摘This paper adopts the NGI-ADP soil model to carry out finite element analysis,based on which the effects of soft clay anisotropy on the diaphragm wall deflections in the braced excavation were evaluated.More than one thousand finite element cases were numerically analyzed,followed by extensive parametric studies.Surrogate models were developed via ensemble learning methods(ELMs),including the e Xtreme Gradient Boosting(XGBoost),and Random Forest Regression(RFR)to predict the maximum lateral wall deformation(δhmax).Then the results of ELMs were compared with conventional soft computing methods such as Decision Tree Regression(DTR),Multilayer Perceptron Regression(MLPR),and Multivariate Adaptive Regression Splines(MARS).This study presents a cutting-edge application of ensemble learning in geotechnical engineering and a reasonable methodology that allows engineers to determine the wall deflection in a fast,alternative way. | Runhong Zhang Chongzhi Wu Anthony T.C.Goh Thomas Bohlke Wengang Zhang | 2021 | Geoscience Frontiers2021，12，1： | 9 |
| 5 | Preparation, characterization, pharmacokinetics and anticancer effects of PEGylated β-elemene liposomes显示文摘Objective:This study aimed to develop a new polyethylene glycol(PEG)ylatedβ-elemene liposome(PEG-Lipo-β-E)and evaluate its characterization,pharmacokinetics,antitumor effects and safety in vitro and in vivo.Methods:The liposomes were prepared by ethanol injection and high-pressure micro-jet homogenization.Characterization of the liposomes was conducted,and drug content,entrapment efficiency(EE),in vitro release and stability were studied by ultra-fast liquid chromatography(UFLC)and a liquid surface method.Blood was drawn from rats to establish the pharmacokinetic parameters.The anticancer effect was evaluated in a KU-19-19 bladder cancer xenograft model.Histological analyses were performed to evaluate safety.Results:The PEG-Lipo-β-E showed good stability and was characterized as 83.31±0.181 nm in size,0.279±0.004 in polydispersity index(PDI),-21.4±1.06 mV in zeta potential,6.65±0.02 in pH,5.024±0.107 mg/mL inβ-elemene(β-E)content,and 95.53±1.712%in average EE.The Fourier transform infrared spectroscopy(FTIR)and differential scanning calorimetry(DSC)indicated the formation of PEG-Lipo-β-E.Compared to elemene injection,PEG-Lipo-β-E demonstrated a 1.75-fold decrease in clearance,a 1.62-fold increase in half-life,and a 1.76-fold increase in area under the concentration-time curves(AUCs)from 0 hour to 1.5 hours(P<0.05).PEG-Lipo-β-E also showed an enhanced anticancer effect in vivo.Histological analyses showed that there was no evidence of toxicity to the heart,kidney,liver,lung or spleen.Conclusions:The present study demonstrates PEG-Lipo-β-E as a new formulation with ease of preparation,high EE,good stability,improved bioavailability and antitumor effects. | Bingtao Zhai Qibiao Wu Wengang Wang Mingming Zhang Xuemeng Han Qiujie Li Peng Chen Xiaying Chen Xingxing Huang Guohua Li Qin Zhang Ruonan Zhang Yu Xiang Shuiping Liu Ting Duan Jianshu Lou Tian Xie Xinbing Sui | 2020 | Cancer Biology & Medicine2020，17，1： | 6 |
| 6 | Changes and spatial patterns of the differences between ground and air temperature over the Qinghai-Xizang Plateau显示文摘地面土壤和空气温度( Ts-Ta )之间的差别被从 1960~2000 在 Qinghai-Xizang (西藏)高原上使用地面的数据和 99 个车站的空气温度学习,并且它的空间分发和时间变化趋势被主要部件分析和力量诊断了光谱分析方法。结果证明价值(Ts-Ta ) 在 12 月是在 6 月和最小的最大值。开始的三装载特徵向量,它反映主要空间地异常的结构( Ts-Ta )在 Qinghai-Xizang 高原上,包含矛盾的变化模式在之间西北并且东南的区域,海水平举起的模式反应和地理,并且永久冻土的分发的模式反应。有包括有最小的价值的单调的增加或减少的趋势,基本稳定性模式和抛物线模式的模式的时间进化的四个模式。(Ts-Ta ) 有一个周期的变化大约 2 年。根据第三的空间分发装载特徵向量(Ts-Ta ) 在在冷季节,永久冻土反应区域和季节的冻结的地面的 Qinghai-Xizang 高原上,反应区域被识别。 | ZHANG Wengang LI Shuxun WU Tonghua PANG Qiangqiang | 2007 | Journal of Geographical Sciences2007，17，1： | 5 |
| 7 | Bushen Qiangjin capsule(补肾强筋胶囊) inhibits the Wnt/β-catenin pathway to ameliorate papain-induced knee osteoarthritis in rats显示文摘OBJECTIVE:To evaluate the molecular mechanism underlying the beneficial effect of Bushen Qiangjin capsule(补肾强筋胶囊,BSQJ),a Traditional Chinese Medicine,on knee osteoarthritis(KOA).METHODS:In the present study,32 female Sprague-Dawley rats were randomly divided into four groups:control,KOA,high-dose BSQJ(H-BSQJ),and low-dose BSQJ(L-BSQJ).After successfully establishing the KOA model by intra-articular injection of papain,H-BSQJ and L-BSQJ groups were intragastrically administered 0.243 and 0.122 g/kg BSQJ,respectively,daily for 6 weeks.At the end of the experiment,knee articular cartilage tissues of rats were collected for evaluation by hematoxylin and eosin staining,Safranin O-Fast Green staining,and terminal deoxynucleotidyl transferase-mediated d UTP nick-end labeling assay.Serum interleukin-1βand tumor necrosis factor-αlevels of rats were detected with an enzyme-linked immunosorbent assay method.Gene expression of Wnt-4,β-catenin,Frizzled-2,glycogen synthase kinase-3β(GSK-3β),cysteinyl aspartate-specific proteinases 3 and 9(caspases 3 and 9),collagen typeⅡalpha 1(Col2 a1),and matrix metalloproteinases 1 and 13(MMP-1 and MMP-3)of rat knee articular cartilage was quantified by reverse transcription-quantitative polymerase chain reaction analysis.Wnt-4,β-catenin,Frizzled-2,GSK-3β,cleaved caspase-3,and cleaved caspase-9 protein expression in rat knee articular cartilage was determined by western blot analysis.RESULTS:BSQJ obviously reduced pathological damage and matrix degradation of articular cartilage in KOA rats.Compared with the KOA group,H-BSQJ rats exhibited downregulated m RNA and protein expression of Wnt-4,β-catenin,Frizzled-2,and caspase-3,as well as upregulated m RNA and protein expression of GSK-3β.In addition,H-BSQJ significantly increased m RNA expression of Col2 a1 and decreased m RNA expression of MMP-1 and MMP-13.CONCLUSION:BSQJ exerted a beneficial effect on KOA by a mechanism involving downregulation of the Wnt/β-catenin pathway,which inhibited both cartilage extracellular matrix degradation and chondrocyte apoptosis to ameliorate KOA in rats. | YAO Nan CHEN Guocai LU Yanyan XU Xuemeng ZHAO Chuanxi HUANG Xuejun LIU Wengang PENG Sha WU Huai | 2021 | Journal of Traditional Chinese Medicine2021，41，6： | 5 |
| 8 | MEF2C promotes M1 macrophage polarization and Th1 responses显示文摘The polarization of macrophages to the M1 or M2 phenotype has a pivotal role in inflammation and host defense;however,the underlying molecular mechanism remains unclear.Here,we show that myocyte enhancer factor 2 C(MEF2C)is essential for regulating M1 macrophage polarization in response to infection and inflammation.Global gene expression analysis demonstrated that MEF2C deficiency in macrophages downregulated the expression of M1 phenotypic markers and upregulated the expression of M2 phenotypic markers.MEF2C significantly promoted the expression of interleukin-12 p35 subunit(Il12a)and interleukin-12 p40 subunit(Il12b).Myeloid-specific Mef2c-knockout mice showed reduced IL-12 production and impaired Th1 responses,which led to susceptibility to Listeria monocytogenes infection and protected against DSS-induced IBD in vivo.Mechanistically,we showed that MEF2C directly activated the transcription of Il12a and Il12b.These findings reveal a new function of MEF2C in macrophage polarization and Th1 responses and identify MEF2C as a potential target for therapeutic intervention in inflammatory and autoimmune diseases. | Xibao Zhao Qianqian Di Han Liu Jiazheng Quan Jing Ling Zizhao Zhao Yue Xiao Han Wu Zherui Wu Wengang Song Huazhang An Weilin Chen | 2022 | Cellular & Molecular Immunology2022，19，4： | 4 |
| 9 | Impact of Non-ideal Waveforms on GaN Power FET in Magnetic Resonant Wireless Power Transfer System显示文摘GaN field-effect transistors(FET)have low conduction and switching losses in high-frequency(>MHz)resonant wireless power transfer systems.Nevertheless,such systems impose a unique stress on GaN FETs owing to their non-ideal voltage waveforms.In this work,we report the observed non-ideal behavior in a 6.78 MHz magnetic resonant wireless transfer system that employs class-D GaN power amplifiers.The non-ideal waveform phenomenon existing at the output of the power amplifier is explained.The study analyzes the causes of this phenomenon,including the coupling coefficient k of the coil,the DC input voltage of the amplifier,and the load on the receiver.Each parameter is simulated and analyzed using LTspice.The influence of the phenomenon on the on-state resistance of the GaN device is proved in an experimental measurement,and the cause of the phenomenon is explained.The study combines a theoretical simulation and an experimental test to discuss the effect of this phenomenon on GaN power devices and proposes the corresponding solutions,which include the limitation of voltage,current,and power of the system,thermal management,and other protection measures. | Shizhen Huang Jianshan Zhang Wengang Wu Ling Xia | 2019 | Chinese Journal of Electrical Engineering2019，5，3： | 1 |
| 10 | Contact Mechanism of Rail Grinding with Open-Structured Abrasive Belt Based on Pressure Grinding Plate显示文摘The current research of abrasive belt grinding rail mainly focuses on the contact mechanism and structural design.Compared with the closed structure abrasive belt grinding,open-structured abrasive belt grinding has excellent performance in dynamic stability,consistency of grinding quality,extension of grinding mileage and improvement of working efficiency.However,in the contact structure design,the open-structured abrasive belt grinding rail using a profiling pressure grinding plate and the closed structure abrasive belt using the contact wheel are different,and the contact mechanisms of the two are different.In this paper,based on the conformal contact and Hertz theory,the contact mechanism of the pressure grinding plate,abrasive belt and rail is analyzed.Through finite element simulation and static pressure experiment,the contact behavior of pressure grinding plate,abrasive belt and rail under single concentrated force,uniform force and multiple concentrated force was studied,and the distribution characteristics of contact stress on rail surface were observed.The results show that under the same external load,there are three contact areas under the three loading modes.The outer contour of the middle contact area is rectangular,and the inner contour is elliptical.In the contact area at both ends,the stress is extremely small under a single concentrated force,the internal stress is drop-shaped under a uniform force,and the internal stress under multiple concentration forces is elliptical.Compared with the three,the maximum stress is the smallest and the stress distribution is more uniform under multiple concentrated forces.Therefore,the multiple concentrated forces is the best grinding pressure loading mode.The research provides support for the application of rail grinding with open-structured abrasive belt based on pressure grinding plate,such as contact mechanism and grinding pressure mode selection. | Zhiwei Wu Wengang Fan Chang Qian Guangyou Hou | 2023 | Chinese Journal of Mechanical Engineering2023，36，2： | 1 |
| 11 | Prediction of lining response for twin tunnels constructed in anisotropic clay using machine learning techniques显示文摘Excessive structural forces generated inside tunnel linings could affect the safety and serviceability of tunnels,emphasizing the need to accurately predict the forces acting on tunnel linings during the preliminary design phase.In this study,an anisotropic soil model devel-oped by Norwegian Geotechnical Institute(NGI)based on the Active-Direct shear-Passive concept(NGI-ADP model)was adopted to conduct finite element(FE)analyses.A total of 682 cases were modeled to analyze the effects of five key parameters on twin-tunnel struc-tural forces;these parameters included twin-tunnel arrangements and subsurface soil properties:burial depth H,tunnel center-to-center distance D,soil strength s_(u)^(A),stiffness ratio G_(u)=s_(u)^(A),and degree of anisotropy ss_(u)^(P)=s_(u)^(A).The significant factors contributing to the bending moment and thrust force of the linings were the tunnel distance and overlying soil depth,respectively.The degree of anisotropy of the surrounding soil was found to be extremely important in simulating the twin-tunnel construction,and severe design errors could be made if the soil anisotropy is ignored.A cutting-edge application of machine learning in the construction of twin tunnels is presented;multivariate adaptive regression splines and decision tree regressor methods are developed to predict the maximum bending moment within the first tunnel’s linings based on the constructed FE cases.The developed prediction model can enable engineers to estimate the structural response of twin tunnels more accurately in order to meet the specific target reliability indices of projects. | Wengang Zhang Yongqin Li Chongzhi Wu Hongrui Li ATC Goh Hanlong Liu | 2022 | Underground Space2022，7，1： | 1 |
| 12 | Mechanism of Wireless Power Transfer System Waveform Distortion Caused by Nonideal Gallium Nitride Transistor Characteristics显示文摘Gallium nitride(GaN)field-effect transistors have low ON resistance and switching losses in high-frequency(>MHz)resonant wireless power transfer systems.Nevertheless,their performance in the system is determined by their characteristics and operation mode.A particular operating mode in a 6.78-MHz magnetic resonant wireless transfer system that employs class-D GaN power amplifiers in the zero-voltage switching mode is studied.Two operation modes,the forward mode and the reverse mode,are investigated.The nonideal effect under the device-level dynamic resistance and thermal effect are also analyzed.The dynamic resistance under different operation modes is demonstrated to have different generation mechanisms.Finally,the device characteristics with system operating conditions are combined,and the effects of temperature and dynamic resistance under different operating conditions are evaluated. | Shaoyu Sun Jianshan Zhang Wengang Wu Ling Xia Yufeng Jin | 2021 | Chinese Journal of Electrical Engineering2021，7，2： | 1 |
| 13 | Visualization and digitization of model tunnel deformation via transparent soil testing technique显示文摘With the increasing demand for transportation infrastructure,the construction of urban tunnel systems linking different areas is indispensable.The deformation and the failure process during a tunnel excavation are essential concerns for geotechnical engineers.However,few studies have systematically investigated the effect of the ground loss ratio on tunnel deformation and the inequality between the ground loss ratio and the volume of the settlement trough.An experimental study using the transparent soil testing technique is performed herein for better visualization and digitization purposes.The three dimensional vertical and horizontal deformation patterns of a single tunnel are investigated for both the surface and the stratum right below considering different ground loss ratios.The relationship among the empirical constant of the settlement trough width,buried depth,depth-diameter ratio,and ground loss ratio is presented. | Wengang Zhang Haiyi Zhong Yuzhou Xiang Daifeng Wu Zhikai Zeng Yanmei Zhang | 2022 | Underground Space2022，7，4： | 1 |
| 14 | Assessment of basal heave stability for braced excavations in anisotropic clay using extreme gradient boosting and random forest regression显示文摘A finite-element analysis considering the anisotropy for the undrained shear strength was performed to examine the effects of the total stress-based anisotropic model NGI-ADP(developed by Norwegian Geotechnical Institute based on the Active-Direct simple shear-Passive concept)parameters on the base stability of deep braced excavations in clays.These parameters included the ratio of the plane strain passive shear strength to the plane strain active shear strength s_(u)^(P)=s_(u)^(A),the ratio of the unloading/reloading shear modulus to the plane strain active shear strength G_(ur)=s_(u)^(A),the plane strain active shear strength s_(u)^(A),the unit weight c,the excavation width B,the wall thickness b,and the wall penetration depth D.According to the numerical results for 1778 hypothetical cases,extreme gradient boosting(XGBoost)and random forest regression(RFR)were adopted to predict the factor of safety(FS)against basal heave for deep braced excavations.The results indicated that the anisotropic characteristics of soil parameters need to be considered when determining the FS against basal heave for braced excavation.XGBoost and RFR can yield a reasonable prediction of the FS.This paper presents a cuttingedge application of ensemble learning methods in geotechnical engineering. | Wengang Zhang Runhong Zhang Chongzhi Wu Anthony T.C.Goh Lin Wang | 2022 | Underground Space2022，7，2： | 1 |
| 15 | Effect of KCI on Growth of Carbon Fibers During Carbonization of Phenolic Resin显示文摘Effects of the KCl additions( 1%,3%,5% and7% of the phenolic resin mass) on phase composition and microstructure of the resin carbon and the growth mechanism of carbon fibers were investigated by using commercial liquid phenolic resin as carbon source and micron-scaled KCl as catalyzer,mixing,hexamethylenetetramine solidification treating,carbon-embedded firing at 1 000 ℃ for 3h in order to accelerate the graphitization of phenolic resin during carbonization. The results show that the graphitization degree of resin carbon is improved by catalysis of KCl,numerous carbon fibers with30-200 nm in diameter and 10-20 μm in length and sheet-like carbon in situ grow in resin carbon. The optimal addition of KCl is 5% when lots of carbon fibers can be found in resin carbon,and d002 diffraction peak of graphite appears obviously in the XRD pattern. The growth mechanism of carbon fiber is that the molten KCl at high temperatures absorbs carbonaceous gas from the decomposition of phenolic resin,accelerating the diffusion of solid C atoms in liquid KCl; after the dissolution of C saturates,carbon atoms separate continuously in local parts to form carbon fibers or flakes; meanwhile,the concentration gradient formed by local carbon atoms in the melt offers growth drive for the separation of carbon fibers or flakes on KCl surface. | WU Xiaoxian LI Hongxia LIU Guoqi YANG Wengang MA Tianfei | 2016 | China's Refractories2016，25，2： | 1 |
| 16 | Functional properties of gelation-like protein hydrolysates from scallop(Patinopecten yessoensis) male gonad显示文摘 | JIN Wengang WU Haitao ZHU Beiwei | 2012 | European Food Research and Technology2012，234，5： | 1 |
| 17 | Cavernous vessels around a patent portal trunk in the liver hilum显示文摘 | Xingshun Qi Guohong Han Zhanxin Yin Chuangye He Wengang Guo Jing Niu Kaichu Wu Daiming Fan | 2012 | Abdominal Imaging2012，，3： | 1 |
| 18 | Superior surface electron energy level endows WP_(2) nanowire arrays with N_(2) fixation functions显示文摘Nitrogen reduction reaction(NRR)under ambient conditions is always a long-standing challenge in science,due to the extreme difficulty in breaking the strong N≡N triple bond.The key to resolving this issue undoubtedly lies in searching superior catalysts to efficiently activate and hydrogenate the stable nitrogen molecules.We herein evaluate the feasibility of WP_(2) for N2 activation and reduction,and first demonstrate WP_(2) with an impressive ammonia yield rate of 7.13 lg h^(-1)cm^(-2),representing a promising W-based catalyst for NRR.DFT analysis further reveals that the NRR catalysis on WP_(2) proceeds in a distal reaction pathway,and the exceptional NRR activity is originated from superior surface electron energy level matching between WP_(2) and NRR potential which facilitates the interfacial proton-coupled electron transfer dynamics.The successfully unraveling the intrinsic catalytic mechanism of WP_(2) for NRR could offer a powerful platform to manipulate the NRR activity by tuning the electron energy levels. | Dongdong Han Xiaojing Liu Jinyan Cai Yufang Xie Shuwen Niu Yishang Wu Yipeng Zang Yanyan Fang Fengqi Zhao Wengang Qu Minghua Chen Gongming Wang Yitai Qian | 2021 | Journal of Energy Chemistry2021，30，8： | 0 |
| 19 | Resistive switching characteristic of electrolyte-oxide-semiconductor structures显示文摘The resistive switching characteristic of SiO_2 thin film in electrolyte-oxide-semiconductor(EOS) structures under certain bias voltage is reported.To analyze the mechanism of the resistive switching characteristic,a batch of EOS structures were fabricated under various conditions and their electrical properties were measured with a set of three-electrode systems.A theoretical model based on the formation and rupture of conductive filaments in the oxide layer is proposed to reveal the mechanism of the resistive switching characteristic,followed by an experimental investigation of Auger electron spectroscopy(AES) and secondary ion mass spectroscopy(SIMS) to verify the proposed theoretical model.It is found that different threshold voltage,reverse leakage current and slope value features of the switching I-V characteristic can be observed in different EOS structures with different electrolyte solutions as well as different SiO_2 layers made by different fabrication processes or in different thicknesses.With a simple fabrication process and significant resistive switching characteristic,the EOS structures show great potential for chemical/biochemical applications. | Xiaoyu Chen Hao Wang Gongchen Sun Xiaoyu Ma Jianguang Gao Wengang Wu | 2017 | Journal of Semiconductors2017，38，8： | 0 |
| 20 | Optimization and Simulation of Inclined Channel Area Lining for CDQ Ovens显示文摘The mechanical force borne by the lintel and“brackets”in the inclined channel area of CDQ and the thermal stress generated by the top-down temperature gradient were simulated by ANSYS software.The following conclusions are drawn.(1)The mechanical force has very mild effect on the damage of the“brackets”.(2)The temperature gradient caused by the uneven temperature distribution of CDQ oven is the key factor affecting the“bracket”damage.The different expansion of refractory materials in various parts results in the thermal stress concentration which tears the“brackets”.(3)The structure adjustment of the“brackets”has very little effect on the thermal stress distribution.(4)The multi-phase nitride bonded silicon carbide for CDQ can effectively alleviate the stress concentration at the“brackets”,realizing the long-life and stable operation. | CAO Huiyan FENG Yanbin ZHANG Haiyan MA Zhaoyang LI Jie WANG Xinhui WU Jiguang YANG Wengang | 2022 | China's Refractories2022，31，2： | 0 |
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