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| 1 | Effect of modified Taohongsiwu decoction on patients with chemotherapy-induced hand-foot syndrome显示文摘OBJECTIVE:To observe the effect of the Traditional Chinese Medicine,modified Taohongsiwu decoction,versus pyridoxine on patients with hand-foot syndrome(HFS)from capecitabine,sorafenib,and gefitinib chemotherapy for gastric,lung,breast,colon,or rectal cancer.Also,to compare quality of life of patients in each group.METHODS:Patients were assigned randomly to group A or B.Group A was given modifiedTaohongsiwu decoction to soak hands and feet for 30 min,once daily.Group B was given 100 mg pyridoxine orally,twice daily.After a 2-week treatment,thetherapeutic effect was assessed by observing three major symptoms,including pain,ulceration,and muscular atrophy.This was assessed with the HFS-14 questionnaire.RESULTS:Significant differences were observed between the two groups in pain relief,and improvement of daily life,walking,and interpersonal communication(P<0.01).No significant differences in driving ability or interpersonal relationships were found.After 2 weeks,the effective rate was 88.3%in group A,which was significantly higher than the50%in group B(P=0.00).CONCLUSION:Modified Taohongsiwu decoction is effective in the treatment of patients with HFS.It improves patients'quality of life according to the HFS-14. | Changlin Zhao Jia Chen Bin Yu Xianlin Wu Congqi Dai Chang Zhou Xiaoyin Chen | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 18 |
| 2 | First stirling-type cryocooler reaching lambda point of ~4He(2.17K) and its prospect in Chinese HUBS satellite project显示文摘The issue of 'missing baryons” is always an unsolved mystery in galaxy cosmology, and an important reason for the great uncertainty of the galaxies' formation and evolution. To find the 'missing' baryons, extra high-resolution spectral observation and imaging of the soft X-ray band (<1 kev) is required. However, the existing observation methods cannot meet this requirement. Therefore, Tsinghua University leads and proposes the Chinese 'Hot Universe Baryon Surveyor (HUBS)' satellite program. | Jue Wang Changzhao Pan Tong Zhang Kaiqi Luo Xiaotong Xi Xianlin Wu Jianpeng Zheng Liubiao Chen Junjie Wang Yuan Zhou Hai Jin Wei Cui | 2019 | Science Bulletin2019，64，4： | 3 |
| 3 | Acute Pancreatitis Complicated by Sheehan's Syndrome: A Case Report and Literature Review显示文摘A 44-year-old woman was transferred to the ICU of the First Affiliated Hospital of Jinan University for 2 days of persistent epigastric pain and 7 hours of unconsciousness.Her admission diagnosis was severe acute necrotizing pancreatitis(hypertriglyceridemia type)with multiple organ dysfunctions.The results of CT revealed a small area of necrotizing pancreatitis,which was not consistent with the severe clinical manifestations.Considering lack of hair and history of postpartum hemorrhage,hormone examination was carried out.According to the results of the examination,she was further diagnosed as Sheehan's syndrome and pituitary crisis.After hormone replacement therapy,her condition improved rapidly. | Dasheng Liu Li Liu Feng Gan Xianlin Wu Gang Ye | 2020 | Chinese Medical Sciences Journal2020，35，1： | 3 |
| 4 | Attaining the liquid helium temperature with a compact pulse tube cryocooler for space applications显示文摘Recent breakthroughs in space science have motivated space exploration programs in many countries including China. Cryocoolers, which provide the mandatory low-temperature environment for many sensitive yet delicate space detectors, are crucial for the proper functioning of various systems. One benchmark for the cryocooler performance is attaining the liquid helium temperature. However, even with complex configurations and multiple driving sources, only a few cryocoolers to date can achieve this goal. Here we report a high-frequency pulse tube cryocooler(HPTC) driven by a single non-oil-lubrication compressor which is capable of reaching the liquid helium temperature while offering other advantages such as high compactness, excellent reliability and high efficiency. The HPTC obtains a no-load temperature of 4.4 K, which is the first realization of cooling below the4 He critical point with a gas-coupled two-stage arrangement. The prototype can provide a cooling power of 87 mW at 8 K, and 5.2 mW at 5 K with a 425 W input electric power, showing leading-level efficiency. Moreover, we demonstrate the ability of the cryocooler to simultaneously provide cooling power at different temperature levels to meet different requirements. Therefore, the prototype developed here could be a promising cryocooler for space applications and beyond. | LIU XuMing CHEN LiuBiao WU XianLin YANG Biao WANG Jue ZHU WenXiu WANG JunJie ZHOU Yuan | 2020 | Science China(Technological Sciences)2020，63，3： | 3 |
| 5 | Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity显示文摘 | Jia Li Caroline Romestaing Xianlin Han Yuan Li Xinbao Hao Yinyuan Wu Chao Sun Xiaolei Liu Leonard S. Jefferson Jingwei Xiong Kathryn F. LaNoue Zhijie Chang Christopher J. Lynch Huayan Wang Yuguang Shi | 2010 | Cell Metabolism2010，，2： | 1 |
| 6 | A controversial premalig- nant lesion显示文摘 | XianLin YI HaoYuan LU Wu YY | 2014 | Oncelogy Letters2014，8，4： | 1 |
| 7 | Sevoflurane effects on cyclic adenosine monophosphate response element binding protein,phosphorylated cyclic adenosine monophosphate response element binding protein,and Livin expression in the cortex and hippocampus of a vascular cognitive impairment rat显示文摘BACKGROUND:Neuronal necrosis and apoptosis play important roles in the pathophysiology of cerebral ischemia and resulting cognitive impairment.However,inhibition of neuronal necrosis and apoptosis has been shown to attenuate cognitive impairment following cerebral ischemia. OBJECTIVE:To investigate the effects of sevoflurane on cyclic adenosine monophosphate response element binding protein(CREB),phosphorylated CREB(pCREB),and Livin expression in the cortex and hippocampus of a rat model of vascular cognitive impairment. DESIGN,TIME AND SETTING:A randomized,controlled experiment was performed in the Chongqing Key Laboratory of Neurology between June 2007 and July 2008. MATERIALS:Sevoflurane was provided by Abbott Laboratory,UK;Morris water maze was provided by Chinese Academy of Medical Sciences,China;goat anti-rat CREB,goat anti-rat pCREB and goat anti-rat Livin antibodies were provided by Biosource International,USA. METHODS:A total of 42 female,Wistar rats were randomly assigned to the following groups:sham operation,vascular cognitive impairment,and sevoflurane treatment.The vascular cognitive impairment rat model was established by permanent bilateral occlusion of both common carotid arteries,and 1.0 MAC sevoflurane was immediately administered by inhalation for 2 hours. MAIN OUTCOME MEASURES:CREB,pCREB,and Livin expression was measured in the cortex and hippocampus by Western blot and reverse transcription-polymerase chain reaction.Behavior was evaluated with Morris water maze. RESULTS:CREB,pCREB,and Livin expression in the sevoflurane treatment group was significantly greater than the vascular cognitive impairment group(P<0.01).However,expression of CREB and pCREB was significantly less in the sevoflurane treatment and vascular cognitive impairment groups,compared with the sham operation group(P<0.01).Livin expression in the sevoflurane treatment and vascular cognitive impairment groups was significantly greater than the sham operation group(P<0.01).Learning,memory,and behavior disorders were observed in the vascular cognitive impairment group.Sevoflurane treatment significantly improved these observed disorders. CONCLUSION:Sevoflurane improved cognitive impairment due to permanent bilateral occlusion of both common carotid arteries.Improved function was associated with increased CREB,pCREB,and Livin expression in the cortex and hippocampus. | Bin Wu Ling Dan Xianlin Zhu | 2009 | Neural Regeneration Research2009，4，7： | 0 |
| 8 | Laparoscopic radical distal pancreatectomy with portal venous tumor thrombectomy for the treatment of pancreatic acinar cell carcinoma after neoadjuvant chemotherapy显示文摘We have read the article“Current status and future prospect of surgical treatment for pancreatic cancer”,published in HepatoBiliary Surgery and Nutrition in 2020(1).This article mentions that in the past two decades,there has been significant development and progress in the surgical treatment of pancreatic cancer,significantly improving the tumor resection rate and reducing perioperative mortality and the incidence of severe complications. | Mengqing Sun Xuesong Bai Xiaoyan Chang Huanwen Wu Yuejuan Cheng Xiaodong He Xianlin Han | 2023 | Hepatobiliary Surgery and Nutrition2023，12，6： | 0 |
| 9 | Analysis of one dimensional and two dimensional fuzzy controllers显示文摘The analytical structures and the correspondin g mathematical properties of the one dimensional and two dimensional fuzzy control lers are first investigated in detail. The nature of these two kinds of fuzzy co ntrollers is next probed from the perspective of control engineering. For the on e dimensional fuzzy controller, it is concluded that this controller is a combin ation of a saturation element and a nonlinear proportional controller, and the s ystem that employs the one dimensional fuzzy controller is the combination of an open-loop control system and a closed-loop control system. For the latter cas e, it is concluded that it is a hybrid controller, which comprises the saturatio n part, zero-output part, nonlinear derivative part, nonlinear proportional par t, as well as nonlinear proportional-derivative part, and the two dimensional f uzzy controller-based control system is a loop-varying system with varying num ber of control loops. | Ban Xiaojun Gao Xiaozhi Huang Xianlin Wu Tianbao | 2006 | Journal of Systems Engineering and Electronics2006，17，2： | 0 |
| 10 | Digestive tract reconstruction in pancreaticoduodenectomy in University Hospitals of China: a national questionnaire survey显示文摘Background Pancreaticoduodenectomy(PD)has been widely applied in general hospitals in China;however,there is still a lack of unified standards for each surgical technique and procedure.This survey is intended to investigate the current status of digestive tract reconstruction after PD in university hospitals in China.Method A cross-sectional survey was conducted among the members of the Young Elite Pancreatic Surgery Club of China by using the Questionnaire for Digestive Tract Reconstruction after Pancreaticoduodenectomy.The questionnaire was disseminated and collected by point-to-point communication via WeChat public platforms.Results A total of 73 valid questionnaires were returned from 65 university hospitals in 28 provincial divisions of China's Mainland.The respondents who performed PD surgery with an annual volume of over 100 cases accounted for 63%.Generally,laparoscopic PD was performed less often than open PD.Child and Whipple reconstructions accounted for 70%and 26%,respectively.The sequence of pancreatoenteric,biliary-enteric,and gastrointestinal reconstruction accounted for 84%of cases.In pancreatoenteric anastomosis,double-layer anastomosis is the most commonly employed type,accounting for approximately 67%,while single-layer anastomosis accounts for 30%.Of the double-layer anastomoses,duct-to-mucosa/dunking(94%/4%)PJ was performed with duct-mucosa using the Blumgart method(39%)and Cattel-Warren(29%),with continuous/interrupted sutures in the inner layer(69%/31%)and continuous/interrupted sutures in the outer layer(53%/23%).In single-layer anastomosis,continuous/interrupted sutures accounted for 41%/45%.In hepatojejunostomy,single-layer/double-layer suture accounted for 79%/4%,and continuous/interrupted suture accounted for 75%/9%.Forty-six percent of the responding units had not applied double-layer biliary-intestinal anastomosis in the last 3 years,75%of the responding surgeons chose the anastomosis method according to bile duct diameter,with absorbable/non-absorbable suture accounting for 86%/12%.PD/pylorus-preserving PD accounted for 79%/11%of GJ cases,the distance between GJ and HJ<30 cm,30-50 cm and>50 cm were 11%,75%,and 14%,respectively.Antecolic/retrocolic GJ accounted for 71%/23%of cases.Twenty-two percent of GJ cases employed Braun anastomosis,while 55%and 19%of GJ cases used linear cutting staplers/tube-type staplers,respectively;60%/14%were reinforced/not reinforced via manual suturing after stapler anastomosis.Manual anastomosis in GJ surgery employed absorbable/non-absorbable sutures(91%/9%).Significant differences in reconstruction techniques were detected between different volumes of PD procedures(<100/year and>100/year),regions with different economic development levels,and between north and south China.Conclusion Digestive tract reconstruction following PD exists heterogeneity in Chinese university hospitals.Corresponding prospective clinical studies are needed to determine the consensus on pancreatic surgery that meets the clinical reality in China. | Jishu Wei Qiang Xu Yuhua Zhang Jiabin Jin Xiaodong Tian Qiaofei Liu Zipeng Lu Zheng Wang Shanmiao Gou Song Gao Xianlin Han Yefei Rong Niandong Ji Ye Lin Guolin Li Shi Chen Feng Cao Hua Chen Wenming Wu Yupei Zhao the Young Elite Pancreatic Surgery Club of China | 2022 | Journal of Pancreatology2022，5，3： | 0 |
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