|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock显示文摘Inflammasomes 是触发 caspase-1 的激活和 interleukin-1β 的成熟的多蛋白质建筑群;(IL-1β) ,然而,这些建筑群的规定仍然保持糟糕描绘了。这里,我们显示出那氮的氧化物(没有) 禁止了调停 NLRP3 的 ASC pyroptosome 形成, caspase-1 激活和 IL-1β在从老鼠和人的 myeloid 房间的分泌物。同时,内长不否定地也源于 iNOS (没有 synthase 的可诱导的形式) 调整 NLRP3 inflammasome 激活。iNOS 的弄空响应 LPS 和 ATP 导致了不正常的线粒体的增加的累积,它为增加的 IL-1β 负责;生产和 caspase-1 激活。没有生产的 iNOS 缺乏或药理学抑制在 vivo 提高了 NLRP3 依赖的 cytokine 生产,因此在老鼠从导致 LPS 的败血增加死亡,它被 NLRP3 阻止缺乏。我们的结果因此经由线粒体的稳定作为 NLRP3 inflammasome 的一个批评否定管理者不识别。这研究有重要含意让新策略的设计控制 NLRP3 相关的疾病。 | Kairui Mao Shuzhen Chen Mingkuan Chen Yonglei Ma Yan Wang Bo Huang Zhengyu He Yan Zeng Yu Htl Shuhui Sun Jing Li Xiaodong Wu Xiangrui Wang Warren Strober Chang Chen Guangxun Meng Bing Sun | 2013 | Cell Research2013，23，2： | 59 |
| 2 | From concept to reality-A review to the primary test stand and its preliminary application in high energy density physics显示文摘Pulsed power technology,whereas the electrical energy stored in a relative long period is released in much shorter timescale,is an efficient method to create high energy density physics(HEDP)conditions in laboratory.Around the beginning of this century,China Academy of Engineering Physics(CAEP)began to build some experimental facilities for HEDP investigations,among which the Primary Test Stand(PTS),a multi-module pulsed power facility with a nominal current of 10 MA and a current rising time~90 ns,is an important achievement on the roadmap of the electro-magnetically driven inertial confinement fusion(ICF)researches.PTS is the first pulsed power facility beyond 10 TW in China.Therefore,all the technologies have to be demonstrated,and all the engineering issues have to be overcome.In this article,the research outline,key technologies and the preliminary HEDP experiments are reviewed.Prospects on HEDP research on PTS and pulsed power development for the next step are also discussed. | Jianjun Deng Weiping Xie Shuping Feng Meng Wang Hongtao Li Shengyi Song Minghe Xia Ji Ce An He Qing Tian Yuanchao Gu Yongchao Guan Bin Wei Xianbin Huang Xiaodong Ren Jiakun Dan Jing Li Shaotong Zhou Hongchun Cai Siqun Zhang Kunlun Wang Qiang Xu Yujuan Wang Zhaohui Zhang Guilin Wang Shuai Guo Yi He Yiwei Zhou Zhanji Zhang Libing Yang Wenkang Zou | 2016 | Matter and Radiation at Extremes2016，1，1： | 19 |
| 3 | Prostate cancer identification: quantitative analysis of T2-weighted MR images based on a back propagation artificial neural network model显示文摘Computer-aided diagnosis(CAD) systems have been proposed to assist radiologists in making diagnostic decisions by providing helpful information. As one of the most important sequences in prostate magnetic resonance imaging(MRI), image features from T2-weighted images(T2WI) were extracted and evaluated for the diagnostic performances by using CAD. We extracted 12 quantitative image features from prostate T2-weighted MR images. The importance of each feature in cancer identification was compared in the peripheral zone(PZ) and central gland(CG), respectively. The performance of the computer-aided diagnosis system supported by an artificial neural network was tested. With computer-aided analysis of T2-weighted images, many characteristic features with different diagnostic capabilities can be extracted. We discovered most of the features(10/12) had significant difference(P<0.01) between PCa and non-PCa in the PZ, while only five features(sum average, minimum value, standard deviation, 10 th percentile, and entropy) had significant difference in CG. CAD prediction by features from T2 w images can reach high accuracy and specificity while maintaining acceptable sensitivity. The outcome is convictive and helpful in medical diagnosis. | ZHAO Kai WANG ChengYan HU Juan YANG XueDong WANG He LI FeiYu ZHANG XiaoDong ZHANG Jue WANG XiaoYing | 2015 | Science China(Life Sciences)2015，58，7： | 16 |
| 4 | Quantitative analysis of diffusion-weighted magnetic resonance images:differentiation between prostate cancer and normal tissue based on a computer-aided diagnosis system显示文摘Diffusion-weighted imaging(DWI) is considered to be one of the dominant modalities used in prostate cancer(PCa) detection and the assessment of lesion aggressiveness,especially for peripheral zone(PZ) PCa.Computer-aided diagnosis(CAD),which is capable of automatically extracting and evaluating image features,can integrate multiple parameters and improve the detection of PCa.In this study,13 quantitative image features were extracted from DWI by CAD,and diagnostic efficacy was analyzed in both the PZ and transition zone(TZ).The results demonstrated that there was a significant difference(P<0.05) between PCa and non-PCa for nine of the 13 features in the PZ and five of the 13 features in the TZ.Besides,the prediction outcome of CAD had a strong correlation with the DWI scores that were graded by experienced radiologists according to the Prostate Imaging-Reporting and Data System Version 2(PI-RADS v2). | Ge Gao Chengyan Wang Xiaodong Zhang Juan Hu Xuedong Yang He Wang Jue Zhang Xiaoying Wang | 2017 | Science China(Life Sciences)2017，60，1： | 13 |
| 5 | Chimeric antigen receptor T cell targeting EGFRvIII for metastatic lung cancer therapy显示文摘Lung cancer is the most common incident cancer and the leading cause of cancer death. In recent years, the development of tumor immunotherapy especially chimeric antigen receptor T (CAR-T) cell has shown a promising future. Epidermal growth factor receptor variant III (EGFRvlll) is a tumor-specific mutation expressed in various types of tumors and has been detected in non-small cell lung cancer with a mutation rate of 10%. Thus, EGFRvIII is a potential antigen for targeted lung cancer therapy. In this study, CAR vectors were constructed and transfected into virus-packaging cells. Then, activated T cells were infected with retrovirus harvested from stable virus-producing single clone cell lines. CAR expression on the surfaces of the T cells was detected by flow cytometry and Western blot. The function of CAR-T targeting EGFRvIII was then evaluated. The EGFRvIII-CAR vector was successfully constructed and confirmed by DNA sequencing. A stable virus-producing cell line was produced from a single clone by limited dilution. The culture conditions for the cell line, including cell density, temperature, and culture medium were optimized. After infection with retrovirus, CAR was expressed on more than 90% of the T cells. The proliferation of CAR-T cells were induced by cytokine and specific antigen in vitro. More importantly, EGFRvIII-CART specifically and efficiently recognized and killed A549-EGFRvIII cells with an effector/target ratio of 10:1 by expressing and releasing cytokines, including perforin, granzyme B, IFN-γ, and TNF-α. The in vivo study indicated that the metastasis of A549-EGFRvIII cells in mice were inhibited by EGFRvIII-CART cells, and the survival of the mice was significantly prolonged with no serious side effects. EGFRvIII-CART showed significantly efficient antitumor activity against lung cancer cells expressing EGFRvlll in vivo and in vitro. Therefore, CAR-T targeting EGFRvIII is a potential therapeutic strategy in preventing recurrence and metastasis of lung cancer after surgery. | Zhao Zhang Jun Jiang Xiaodong Wu Mengyao Zhang Dan Luo Renyu Zhang Shiyou Li Youwen He Huijie Bian Zhinan Chen | 2019 | Frontiers of Medicine2019，13，1： | 11 |
| 6 | Marginal optimization method to improve the inconsistent comparison matrix in the analytic hierarchy process显示文摘To improve the inconsistency in the analytic hierarchy process(AHP), a new method based on marginal optimization theory is proposed. During the improving process, this paper regards the reduction of consistency ratio(CR) as benefit, and the maximum modification compared to the original pairwise comparison matrix(PCM) as cost, then the improvement of consistency is transformed to a benefit/cost analysis problem. According to the maximal marginal effect principle, the elements of PCM are modified by a fixed increment(or decrement) step by step till the consistency ratio becomes acceptable, which can ensure minimum adjustment to the original PCM so that the decision makers' judgment is preserved as much as possible. The correctness of the proposed method is proved mathematically by theorem. Firstly, the marginal benefit/cost ratio is calculated for each single element of the PCM when it has been modified by a fixed increment(or decrement).Then, modification to the element with the maximum marginal benefit/cost ratio is accepted. Next, the marginal benefit/cost ratio is calculated again upon the revised matrix, and followed by choosing the modification to the element with the maximum marginal benefit/cost ratio. The process of calculating marginal effect and choosing the best modified element is repeated for each revised matrix till acceptable consistency is reached, i.e., CR<0.1. Finally,illustrative examples show the proposed method is more effective and better in preserving the original comparison information than existing methods. | Shihui Wu Jiang Xie Xiaodong Liu Bo He Minxiang Yang Zhengxin Li | 2017 | Journal of Systems Engineering and Electronics2017，28，6： | 11 |
| 7 | Corrosion mechanism investigation of TiN/Ti coating and TC4 alloy for aircraft compressor application显示文摘It is imperative to develop multifunctional erosion and corrosion resistant coatings for compressor blades of aircraft engines in harsh environment.PVD(Physical Vapor Deposition)technology has the advances in processing erosion-resistant coatings;however,the performance of PVD coatings to combat corrosion depends on various coating defects.Determining and comparing the corrosion performances of PVD TiN/Ti coating and uncoated TC4 alloy was the main objective of present work.The 960 h salt spray corrosion and 116 h hot corrosion tests were conducted to simulate the grounding and working environments of the aircraft compressors.The corrosion mechanisms due to the coating defects such as pinhole,columnar boundary and large grain were analyzed based on the OM,Confocal microscope,electrochemical measurements,SEM,XRD and EDS results.Owing to the disordered state associated with the columnar boundary and the coating defect,nitrogen could be easily replaced by oxygen in the hot corrosion process,these structures were channels for fast diffusion of oxygen.Moreover,the Gibbs energy changes of Ti oxidation and TiN oxidation were thermodynamically calculated according to the working condition of aircraft compressors,and considerable research effort was focused on mapping out the phase diagram of Ti,TiN and high pressure gases.The findings of this research can provide insights into developing multifunctional coatings for future aircraft engines. | Zhiping SUN Guangyu HE Qingjie MENG Yuqin LI Xiaodong TIAN | 2020 | Chinese Journal of Aeronautics2020，33，6： | 11 |
| 8 | Facilitating Lithium-Ion Diffusion in Layered Cathode Materials by Introducing Li^(+)/Ni^(2+) Antisite Defects for High-Rate Li-Ion Batteries显示文摘Li^(+)/Ni^(2+) antisite defects mainly resulting from their similar ionic radii in the layered nickel-rich cathode materials belong to one of cation disordering scenarios.They are commonly considered harmful to the electrochemical properties,so a minimum degree of cation disordering is usually desired.However,this study indicates that LiNi_(0.8)Co_(0.15)Al_(0.05)O_(2)as the key material for Tesla batteries possesses the highest rate capability when there is a minor degree(2.3%)of Li^(+)/Ni^(2+) antisite defects existing in its layered structure.By combining a theoretical calculation,the improvement mechanism is attributed to two effects to decrease the activation barrier for lithium migration:(1)the anchoring of a low fraction of high-valence Ni^(2+) ions in the Li slab pushes uphill the nearest Li^(+)ions and(2)the same fraction of low-valence Li^(+) ions in the Ni slab weakens the repulsive interaction to the Li^(+) ions at the saddle point. | Zhongfeng Tang Sen Wang Jiaying Liao Shuo Wang Xiaodong He Bicai Pan Haiyan He Chunhua Chen | 2019 | Research2019，，1： | 8 |
| 9 | Single atoms in the ring lattice for quantum information processing and quantum simulation显示文摘We have demonstrated preparing and rotating single neutral rubidium atoms in an optical ring lattice generated by a spatial light modulator, inserting two atoms into a single microscopic optical potential efficiently by dynamically reshaping the optical dipole trap, trapping single atoms in a blue detuned optical bottle beam trap, and confining single atoms into the Lamb-Dicke regime by combining red and blue detuned optical potentials. In combination with the manipulation of internal states of single atoms, the study is opening a way for research in the field of quantum information processing and quantum simulation. In this paper we review the past works and discuss the prospects. | YU Shi HE XiaoDong XU Peng LIU Min WANG Jin ZHAN MingSheng | 2012 | Chinese Science Bulletin2012，57，16： | 8 |
| 10 | Dynamically controlling terahertz wavefronts with cascaded metasurfaces显示文摘Dynamically controlling terahertz(THz)wavefronts in a designable fashion is highly desired in practice.However,available methods working at microwave frequencies do not work well in the THz regime due to lacking suitable tunable elements with submicrometer sizes.Here,instead of locally controlling individual meta-atoms in a THz metasurface,we show that rotating different layers(each exhibiting a particular phase profile)in a cascaded metadevice at different speeds can dynamically change the effective Jonesmatrix property of the whole device,thus enabling extraordinary manipulations on the wavefront and polarization characteristics of a THz beam impinging on the device.After illustrating our strategy based on model calculations,we experimentally demonstrate two proof-of-concept metadevices,each consisting of two carefully designed all-silicon transmissive metasurfaces exhibiting different phase profiles.Rotating two metasurfaces inside the fabricated devices at different speeds,we experimentally demonstrate that the first metadevice can efficiently redirect a normally incident THz beam to scan over a wide solid-angle range,while the second one can dynamically manipulate both the wavefront and polarization of a THz beam.Our results pave the way to achieving dynamic control of THz beams,which is useful in many applications,such as THz radar,and bio-and chemical sensing and imaging. | Xiaodong Cai Rong Tang Haoyang Zhou Qiushi Li Shaojie Ma Dongyi Wang Tong Liu Xiaohui Ling Wei Tan Qiong He Shiyi Xiao Lei Zhou | 2021 | Advanced Photonics2021，3，3： | 8 |
| 11 | Multifractal mass exponent spectrum of complex physiological time series显示文摘Physiological signal belongs to the kind of nonstationary and time-variant ones.Thus,the nonlinear analysis methods may be better to disclose its characteristics and mechanisms.There have been plenty of evidences that physiological signal generated by complex self-regulated system may have a fractal structure.In this work,we introduce a new measure to characterize multifractality,the mass exponent spectrum curvature,which can disclose the complexity of fractal structure from total bending degree of the spectrum.This parameter represents the nonlinear superpositions of the discrepancies of fractal dimension from all adjacent points in the curve and therefore solves the problem of original parameters for not fully reflecting the information of entire subsets in the fractal structure.The evaluations of deterministic fractal system Cantor measure validate that it is completely effective in exploring the complexity of chaotic series,and is also not affected by nonstability of the signal as well as disturbances of the noises.We then apply it to the analysis of human heart rate variability(HRV) signals and sleep electroencephalogram(EEG) signals.The experimental results show that this method can be better to discriminate cohorts under different physiological and pathological conditions.Compared with the indicator of singularity spectrum width,there are some improvements both on the computing efficiency and accuracy.Such conclusion may provide some valuable information for clinical diagnoses. | YANG XiaoDong HE AiJun ZHOU Yong NING XinBao | 2010 | Chinese Science Bulletin2010，55，19： | 7 |
| 12 | Construction of adaptive redundant multiwavelet packet and its application to compound faults detection of rotating machinery显示文摘It is significant to detect the fault type and assess the fault level as early as possible for avoiding catastrophic accidents.Due to diversity and complexity,the compound faults detection of rotating machinery under non-stationary operation turns to be a challenging task.Multiwavelet with two or more base functions may match two or more features of compound faults,which may supply a possible solution to compound faults detection.However,the fixed basis functions of multiwavelet transform,which are not related with the vibration signal,may reduce the accuracy of compound faults detection.Moreover,the decomposition results of multiwavelet transform not being own time-invariant is harmful to extract the features of periodical impulses.Furthermore,multiwavelet transform only focuses on the multi-resolution analysis in the low frequency band,and may leave out the useful features of compound faults.To overcome these shortcomings,a novel method called adaptive redundant multiwavelet packet(ARMP) is proposed based on the two-scale similarity transforms.Besides,the relative energy ratio at the characteristic frequency of the concerned component is computed to select the sensitive frequency bands of multiwavelet packet coefficients.The proposed method was used to analyze the compound faults of rolling element bearing.The results showed that the proposed method could enhance the ability of compound faults detection of rotating machinery. | CHEN JingLong ZI YanYang HE ZhengJia WANG XiaoDong | 2012 | Science China(Technological Sciences)2012，55，8： | 7 |
| 13 | Influence of EDTA on Demineralization Rate of Dentine:Calcification Treatment in Root Canal Therapy显示文摘The aim of this study was to investigate the influence of ethylenediaminetetraacetic acid(EDTA) irrigation on demineralization rate of dentine located in the apical third of root canal walls.Teeth were divided into A and B two groups.In group A,all of the teeth was irrigated with EDTA and NaOCI(sodium hypochlorite),followed by cutting the apical third into slices longitudinally to examine the influence of EDTA on different portions of apical third of root canal.In group B,the apical third of a tooth was firstly cut into slices longitudinally,followed by coating the root canal walls with EDTA to in-situ observe the demineralization of dentine with different time.It was found that the influence of EDTA on root-canal was gradually increased from the apical to the upper end of the apical third for group A.In addition,the demineralization rate of dentine was remarkable in the first 25 min for group B.The diffusion of EDTA into root dentine would lead to potential damage to the dentine.Furthermore,demineralization rate curve was calculated. | Yang Ji Min He Shijie Chang Xiaodong Zhang Huazhe Yang | 2014 | Journal of Materials Science & Technology2014，30，7： | 7 |
| 14 | The Improved Characteristics of Bionic Gabor Representations by Combining with SIFT Key-points for Iris Recognition显示文摘 | Yuanning Liu Fei He Xiaodong Zhu Zhen Liu Ying Chen Ye Han Lijiao Yu | 2015 | Journal of Bionic Engineering2015，12，3： | 6 |
| 15 | Comprehensive contour prediction model of work rolls in hot wide strip mill显示文摘The predictive calculation of comprehensive contour of work rolls in the on-line strip shape control model during hot rolling consists of two important parts of wear contour calculation and thermal contour calculation, which have a direct influence on the ac- curacy of shape control. A statistical wear model and a finite difference thermal contour model of work rolls were described. The comprehensive contour is the equivalence treatment of the sum of grinding, wear, and thermal contours. This comprehensive contour calculation model has been applied successfully in the real on-line strip shape control model. Its high precision has been proved through the large amounts of actual roll profile measurements and theoretical analyses. The hit rates (percent of shape index satisfying re- quirement) of crown and head flatness of the strips rolled, by using the shape control model, which includes the comprehensive contour calculation model, have about 16% and 10% increase respectively, compared to those of strips rolled by using manual operation. | Xiaodong Wang Quan Yang Anrui He Renzhong Wang | 2007 | Journal of University of Science and Technology Beijing2007，14，3： | 6 |
| 16 | Abundance and biomass of heterotrophic microbes in the Kongsfjorden, Svalbard显示文摘Abundance and biomass of heterotrophic microbes were investigated using epifluorescense microscopy in August 2004 along a transect in the Kongsfjorden, a glacial fjord in the high arctic, located in the north-western part of Svalbard. A bacterial abundance was low at outer fjord stations (on average 2.29×108 ind./dm3) and was higher at inner fjord stations (on average 3.52×108 ind./dm3).The biomass of bacteria ranged from 3.69 to 8.01 mg/m3.The abundance of bacteria was low at the surface of water(0 m), whereas the higher abundances often occurred at depths of 30~50 m.The abundance of heterotrophic flagellates varied from 2.785 to 8.891×104 ind./dm3.The assemblage was numerically dominated by less than 5 μm heterotrophic flagellates (78.67%~94.80%).The biomass of heterotrophic flagellates varied from 0.37 to 2.30 mg/m3.The mean biomass distribution for all stations was 4.91% for less than 5 μm heterotrophic flagellates, 86.74% for 6~20 μm flagellates and 8.35% for greater than 20 μm sized flagellates.The low biomass of heterotrophic flagellates often occurred at the surface of water(0 m),while the maximum value of biomass occurred at different depths. The biomass of total heterotrophic microbial community ranged from 4.20 to 10.03 mg/m3.The mean biomass distribution for all stations was 82.58% for bacteria, 15.77% for flagellates and 1.66% for ciliates. | JIANG Xiaodong HE Jianfeng CAI Minghong | 2005 | Acta Oceanologica Sinica2005，24，6： | 6 |
| 17 | Role of Microphysical Parameterizations with Droplet Relative Dispersion in IAP AGCM 4.1显示文摘Previous studies have shown that accurate descriptions of the cloud droplet effective radius(Re) and the autoconversion process of cloud droplets to raindrops(Ar) can effectively improve simulated clouds and surface precipitation, and reduce the uncertainty of aerosol indirect effects in GCMs. In this paper, we implement cloud microphysical schemes including two-moment Ar and Re considering relative dispersion of the cloud droplet size distribution into version 4.1 of the Institute of Atmospheric Physics' s atmospheric GCM(IAP AGCM 4.1), which is the atmospheric component of the Chinese Academy of Sciences' Earth System Model. Analysis of the effects of different schemes shows that the newly implemented schemes can improve both the simulated shortwave and longwave cloud radiative forcings, as compared to the standard scheme, in IAP AGCM 4.1. The new schemes also effectively enhance the large-scale precipitation, especially over low latitudes, although the influences of total precipitation are insignificant for different schemes. Further studies show that similar results can be found with the Community Atmosphere Model, version 5.1. | Xiaoning XIE He ZHANG Xiaodong LIU Yiran PENG Yangang LIU | 2018 | Advances in Atmospheric Sciences2018，35，2： | 6 |
| 18 | Evaluation of the New Dynamic Global Vegetation Model in CAS-ESM显示文摘In the past several decades, dynamic global vegetation models(DGVMs) have been the most widely used and appropriate tool at the global scale to investigate vegetation-climate interactions. At the Institute of Atmospheric Physics, a new version of DGVM(IAP-DGVM) has been developed and coupled to the Common Land Model(CoLM) within the framework of the Chinese Academy of Sciences' Earth System Model(CAS-ESM). This work reports the performance of IAP-DGVM through comparisons with that of the default DGVM of CoLM(CoLM-DGVM) and observations. With respect to CoLMDGVM, IAP-DGVM simulated fewer tropical trees, more 'needleleaf evergreen boreal tree' and 'broadleaf deciduous boreal shrub', and a better representation of grasses. These contributed to a more realistic vegetation distribution in IAP-DGVM,including spatial patterns, total areas, and compositions. Moreover, IAP-DGVM also produced more accurate carbon fluxes than CoLM-DGVM when compared with observational estimates. Gross primary productivity and net primary production in IAP-DGVM were in better agreement with observations than those of CoLM-DGVM, and the tropical pattern of fire carbon emissions in IAP-DGVM was much more consistent with the observation than that in CoLM-DGVM. The leaf area index simulated by IAP-DGVM was closer to the observation than that of CoLM-DGVM; however, both simulated values about twice as large as in the observation. This evaluation provides valuable information for the application of CAS-ESM, as well as for other model communities in terms of a comparative benchmark. | Jiawen ZHU Xiaodong ZENG Minghua ZHANG Yongjiu DAI Duoying JI Fang LI Qian ZHANG He ZHANG Xiang SONG | 2018 | Advances in Atmospheric Sciences2018，35，6： | 6 |
| 19 | Research on robust mean square stability of networked control systems with packet dropout显示文摘This paper is concerned with the robust stabilization problem of networked control systems with stochastic packet dropouts and uncertain parameters. Considering the stochastic packet dropout occuring in two channels between the sensor and the controller, and between the controller and the actuator, networked control systems are modeled as the Markovian jump linear system with four operation modes. Based on this model, the necessary and sufficient conditions for the mean square stability of the deterministic networked control systems and uncertain networked control systems are given by using the theory of the Markovian jump linear system, and corresponding controller design procedures are proposed via the cone complementarity linearization method. Finally, the numerical example and simulations are given to illustrate the effectiveness of the proposed results. | Dexiao Xie Xiaodong Han He Huang Zhiquan Wang | 2010 | Journal of Systems Engineering and Electronics2010，21，1： | 5 |
| 20 | Heterogeneously integrated,superconducting silicon-photonic platform for measurementdevice-independent quantum key distribution显示文摘Integrated photonics provides a route to both miniaturization of quantum key distribution(QKD)devices and enhancing their performance.A key element for achieving discrete-variable QKD is a singlephoton detector.It is highly desirable to integrate detectors onto a photonic chip to enable the realization of practical and scalable quantum networks.We realize a heterogeneously integrated,superconducting silicon-photonic chip.Harnessing the unique high-speed feature of our optical waveguide-integrated superconducting detector,we perform the first optimal Bell-state measurement(BSM)of time-bin encoded qubits generated from two independent lasers.The optimal BSM enables an increased key rate of measurement-device-independent QKD(MDI-QKD),which is immune to all attacks against the detection system and hence provides the basis for a QKD network with untrusted relays.Together with the timemultiplexed technique,we have enhanced the sifted key rate by almost one order of magnitude.With a 125-MHz clock rate,we obtain a secure key rate of 6.166 kbps over 24.0 dB loss,which is comparable to the state-of-the-art MDI-QKD experimental results with a GHz clock rate.Combined with integrated QKD transmitters,a scalable,chip-based,and cost-effective QKD network should become realizable in the near future. | Xiaodong Zheng Peiyu Zhang Renyou Ge Liangliang Lu Guanglong He Qi Chen Fangchao Qu Labao Zhang Xinlun Cai Yanqing Lu Shining Zhu Peiheng Wu Xiao-Song Ma | 2021 | Advanced Photonics2021，3，5： | 5 |
您所在的机构暂未开通此部分的功能，请联系管理员