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| 1 | Pulmonary adenocarcinoma with signet ring cell features:A comprehensive study from 3 distinct patient cohorts显示文摘 | Boland JM Wampfler JA Jang JS | 2014 | Am J Surg Pathol2014，38，12： | 1 |
| 2 | Correlation of IHC and FISH for ALK Gene Rearrangement in Non-small Cell Lung Carcinoma: IHC Score Algorithm for FISH显示文摘 | Eunhee S. Yi Jennifer M. Boland Joseph J. Maleszewski Anja C. Roden Andre M. Oliveira Marie-Christine Aubry Michele R. Erickson-Johnson Bolette L. Caron Yan Li Hui Tang Shawn Stoddard Jason Wampfler Kimary Kulig Ping Yang | 2011 | Journal of Thoracic Oncology2011，，3： | 1 |
| 3 | Quality of Life and Symptom Burden among Long-Term Lung Cancer Survivors显示文摘 | Ping Yang Andrea L. Cheville Jason A. Wampfler Yolanda I. Garces Aminah Jatoi Matthew M. Clark Stephen D. Cassivi David E. Midthun Randolph S. Marks Marie-Christine Aubry Scott H. Okuno Brent A. Williams Francis C. Nichols Victor F. Trastek Hiroshi Sugimu | 2012 | Journal of Thoracic Oncology2012，，1： | 1 |
| 4 | Quality of life and symptom burden among long-term lung cancer survivors显示文摘 | Yang P Cheville AL Wampfler JA | 2012 | J Thorac 0ncol2012，，： | 1 |
| 5 | Strategies for detection of Plasmodium species gametocytes 显示文摘 | Wampfler R Mwingira F Javati S | 2013 | PLoS One2013，8，76： | 1 |
| 6 | Quality of Life and symptom burden among long-term lung cancer survivors显示文摘 | Yang P Cheville AL Wampfler JA | 2012 | J Thorac Oncol2012，7，1： | 1 |
| 7 | High prevalence of urinary schistosomiasis in a desert population: results from an exploratory study around the Ounianga lakes in Chad显示文摘Background Researching a water-borne disease in the middle of the Sahara desert might not seem the most relevant concern.However,nomadic Sahelian pastoralists health concerns regarding their livestock and anecdotal reports about trematode infections of Fasciola spp.and Schistosoma spp.in desert-raised animals justified an exploratory study focusing on the lakes of Ounianga in Northern Chad.The aim was to test whether trematode parasites such as Schistosoma spp.occur in human populations living around the Sahara desert lakes of Ounianga Kebir and Ounianga Serir in northern Chad.Methods The study was carried out in January 2019 and comprised of three components.First,a cross sectional survey based on a random sample drawn from the population to detect infections with S.haematobium and S.mansoni;second,focus group discussions exploring disease priorities,access to health and health seeking behaviour;and third,surveying water contact sites for intermediate host snails.Samples of trematode parasites and snails were confirmed on species level by molecular genetic methods.For parasitological and malacological surveys descriptive statistics were performed.Qualitative data analysis included the full review of all transcripts,followed by a descriptive and explorative thematic analysis.Results Among 258 participants,the overall S.haematobium prevalence using urine filtration was 39.2%[95%confidence interval(CI):33.5–45.1%],with 51.5%of the infected suffering from heavy infection.The intermediate host snail of S.haematobium(Bulinus truncatus)occurred at water contact sites near both study villages,revealing the potential for local transmission.Although a positive S.mansoni point-of-care circulating cathodic antigen(POC-CCA)test result was obtained from 8.6%(95%CI 5.7–12.8%)of the samples,no intermediate host snails of S.mansoni were found,and the relevance of S.mansoni remains uncertain.Qualitative findings underline the importance of morbidity caused by urinary schistosomiasis,and the lack of access to diagnostics and treatment as a major health concern.Conclusions This research revealed a high prevalence of urinary schistosomiasis in the population living around the lakes of Ounianga in the Sahara,a United Nations Educational,Scientific and Cultural Organization(UNESCO)world heritage site in Chad.Despite the high public health importance of the associated morbidity expressed by the population,there is no access to diagnostics and treatment.Further work is needed to develop and test a context-adapted intervention. | Wendelin Moser Annour Adoum Batil Rebekka Ott Moussa Abderamane Ruth Clements Rahel Wampfler Sven Poppert Peter Steinmann Fiona Allan Helena Greter | 2022 | Infectious Diseases of Poverty2022，11，1： | 0 |
| 8 | Strongyloides stercoralis prevalence and diagnostics in Vientiane, Lao People’s Democratic Republic显示文摘Background:Despite the high prevalence of strongyloidiasis in the Laotian population,Laotian hospitals still lack diagnostic capacity to appropriately diagnose Strongyloides stercoralis infections.This cross-sectional hospital-based study was conducted to assess the prevalence of Strongyloides stercoralis infection among hospitalized patients treated at Mahosot Hospital,the primary reference hospital of Lao People’s Democratic Republic(Lao PDR),and to validate feasible methods for diagnosing S.stercoralis infection at hospital’s laboratory.Methods:Between September and December 2018,stool samples of 104 inpatients were investigated for S.stercoralis infection by wet smear,Baermann technique,Koga Agar plate culture(KAPC),and real-time detection polymerase chain reaction(RTD-PCR)at the Infectious Diseases Ward of the Mahosot Hospital in Vientiane.The sensitivity,the specificity,the negative predictive value(NPV)of each diagnostic test,as well as their combination(s)was calculated using a composite reference standard(CRS).The correlation of the different test methods was assessed by chi-square or Fisher’s exact test.Cohen’s kappa coefficient was used to assess the diagnostic agreement of the different test methods.Results:The overall prevalence of S.stercoralis infections among the study population was 33.4%.The cumulative infection prevalence statistically significantly increased from the lowest age group of 40 years and below(22.4%),to the medium(40.0%)and to the oldest age group of 61 year and above(72.7%)(P=0.003).The cumulative infection prevalence of CRS was considerably higher in male(40.4%)compared to female patients(28.1%),but not statistically different(P=0.184).The diagnostic sensitivity of Baermann technique,KAPC,RTD-PCR,and the combination of Baermann technique and KAPC were 60.0,60.0,74.3,and 77.1%,respectively.Only 13 patients(37.1%)of the total 35 S.stercoralis patients diagnosed with any technique had a simultaneously positive diagnostic test with Baermann,KAPC and RTD-PCR.Conclusions:We identified Baermann technique and KAPC to be currently the most feasible and implementable standard methods for diagnosing S.stercoralis at a hospital setting such as Mahosot Hospital and provincial and district hospitals in Lao PDR and other low-and middle income countries in Southeast Asia.Trial registration:This study was approved by the National Ethics Committee for Health Research in Lao PDR(reference no.083/NECHR)and by the Ethics Committee Northwest and Central Switzerland(reference no.2018–00594). | Somaphone Chankongsin Rahel Wampfler Marie-Therese Ruf Peter Odermatt Hanspeter Marti Beatrice Nickel Valy Keoluangkhot Andreas Neumayr | 2020 | Infectious Diseases of Poverty2020，9，5： | 0 |
| 9 | 伴印戒细胞特征的肺腺癌:3组不同患者的综合性分析显示文摘目前有关伴印戒细胞特征(SRC)肺腺癌的综合性生物学特性仍然未知。因此作者系统性的评估伴SRC临床病理特点和组织学分子特征,特别是其与吸烟间的关系。复习3组随访时间均≥5年的经外科切除的肺腺癌患者(n=763)。2位病理学家同意≥10%的区域伴SRC判断为SRC。对伴SRC病例进行ALK和ROS1重排检测,以及包括EGFR、KRAS、BRAF、ERBB2、JAK2、AKT1、AKT2、KIT、MET和PIK3CA 10个突变基因的检测。 | Boland J M Wampfler J A Jang J S 魏建国 刘勇 | 2015 | 临床与实验病理学杂志2015，31，1： | 0 |
| 10 | 打碟的奥秘——3年级学生用不含橡胶的材料探索静电显示文摘静电和电荷这一单元是3年级学生的最爱,因为探究和动手实践会让学生们很兴奋。然而,如果不使用橡胶,教师在设计静电相关课程时会感到比较困难。因为橡胶过敏是一个严重的问题,但如果课程中不用气球,就需要教师开动脑筋用其他不导电的聚合物演示静电,并且让学生参与其中。本文描述了一项以学生为主导的和静电有关的3年级学生课程, | Rebecca Wampfler Rachelle Haroldson 张为 | 2017 | 中国科技教育2017，0，3： | 0 |
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