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| 1 | Endovascular treatment of blood blister-like aneurysms in the internal carotid artery using a Willis covered stent显示文摘Background Despite the current availability of flow diverter devices(FDD), problems remains regarding optimal endovascular treatment(EVT) for blood blister-like aneurysms(BBAs) of the internal carotid artery(ICA). Objective To evaluate the safety and efficacy of EVT of BBAs in the ICA with a Willis covered stent. Methods 20 consecutive patients(5 men and 15 women) with ruptured BBAs underwent EVT using a Willis covered stent in two institutions from March 2013 to March 2018. Clinical observations, angiographic characteristics, and procedural and follow-up outcomes were retrospectively evaluated. Results 20 consecutive patients(5 men and 15 women) with ruptured BBAs underwent EVT using a Willis covered stent in two institutions from March 2013 to March 2018. Clinical observations, angiographic characteristics, and procedural and follow-up outcomes were retrospectively evaluated. Conclusion Our initial results demonstrate that reconstructive EVT using a Willis covered stent provides a viable approach to treat ICA BBAs. However, an expanded clinical evaluation and larger cohort are needed to confirm the results. | Yi Gu Binxian Gu Yongdong Li Yueqi Zhu Haitao Lu Liming Wei Mo Chen Minhua Li Jieqing Wan Wu Wang | 2018 | Journal of Interventional Medicine2018，1，3： | 8 |
| 2 | Allele-defined genome reveals biallelic differentiation during cassava evolution显示文摘Dear Editor,Generation of heterozygous genomes by hybridization between or within species can help maintain plant diversity and serve as a potential source of new species(Baek et al.,2018).Moreover,genomic heterozygosity is associated with genomic coadaptation,developmental stability,and heterosis.Accurate definition of alleles in haplotypes is necessary to precisely characterize allelic variation controlling agriculturally important traits(Shi et al.,2019).Currently,most released genomes have mosaic assembly of haplotypes due to random selection or collapse of alleles during genome assembly(Shi et al.,2019),which masked allelic variation and functional differentiation of divergent alleles in heterozygous species. | Wei Hu Changmian Ji Haitao shi Zhe Liang Zehong Ding Jianqiu Ye Wenjun Ou Gang Zhou Weiwei Tie Yan Yan Jinghao Yang Xiaoying Yang Yunxie Wei Zhiqiang Jin Jianghui Xie Ming Peng Wenquan Wang Anping Guo Biyu Xu Jianchun Guo Songbi Chen Liming Ma Mingcheng Wang Yang Zhou Xiaolong Li Ruoxi Li Siyi Guo Xinhui Xiao Zhongqing Wan Feifei An Jie Zhang Qingyun Leng Yin Li Ray Ming Kaimian Li | 2021 | Molecular Plant2021，14，6： | 8 |
| 3 | A flow cytometer based protocol for quantitative analysis of bloom-forming cyanobacteria(Microcystis) in lake sediments显示文摘A quantitative protocol for the rapid analysis of Microcystis cells and colonies in lake sediment was developed using a modified flow cytometer,the CytoSense.For cell enumeration,diluted sediment samples containing Microcystis were processed with sonication to disintegrate colonies into single cells.An optimized procedure suggested that 5 mg dw(dry weight)/mL dilution combined with 200 W × 2 min sonication yielded the highest counting efficiency.Under the optimized determination conditions,the quantification limit of this protocol was 3.3×10 4 cells/g dw.For colony analysis,Microcystis were isolated from the sediment by filtration.Colony lengths measured by flow cytometry were similar to those measured by microscopy for the size range of one single cell to almost 400 μm in length.Moreover,the relationship between colony size and cell number was determined for three Microcystis species,including Microcystis flos-aquae,M.aeruginosa and M.wessenbergii.Regression formulas were used to calculate the cell numbers in differentsized colonies.The developed protocol was applied to field sediment samples from Lake Taihu.The results indicated the potential and applicability of flow cytometry as a tool for the rapid analysis of benthic Microcystis.This study provided a new capability for the high frequency monitoring of benthic overwintering and population dynamics of this bloom-forming cyanobacterium. | Quan Zhou Wei Chen Huiyong Zhang Liang Peng Liming Liu Zhiguo Han Neng Wan Lin Li Lirong Song | 2012 | Journal of Environmental Sciences2012，24，9： | 5 |
| 4 | Self-Powered Intelligent Human-Machine Interaction for Handwriting Recognition显示文摘Handwritten signatures widely exist in our daily lives.The main challenge of signal recognition on handwriting is in the development of approaches to obtain information effectively.External mechanical signals can be easily detected by triboelectric nanogenerators which can provide immediate opportunities for building new types of active sensors capable of recording handwritten signals.In this work,we report an intelligent human-machine interaction interface based on a triboelectric nanogenerator.Using the horizontal-vertical symmetrical electrode array,the handwritten triboelectric signal can be recorded without external energy supply.Combined with supervised machine learning methods,it can successfully recognize handwritten English letters,Chinese characters,and Arabic numerals.The principal component analysis algorithm preprocesses the triboelectric signal data to reduce the complexity of the neural network in the machine learning process.Further,it can realize the anticounterfeiting recognition of writing habits by controlling the samples input to the neural network.The results show that the intelligent human-computer interaction interface has broad application prospects in signature security and humancomputer interaction. | Hang Guo Ji Wan Haobin Wang Hanxiang Wu Chen Xu Liming Miao Mengdi Han Haixia Zhang | 2021 | Research2021，，1： | 4 |
| 5 | A family net of giant pandas in the Tangjiahe Natural Reserve:Assessment of current individual migration显示文摘In the present study, formalin-fixed feces, oli-gonucleotide fingerprinting and SRY-gene based sexing were used to construct a family net for giant pandas in the Tang-jiahe Natural Reserve and to assess contemporary gene flow (migration) in this population. A total of 124 fecal samples were attributed to 37 individuals (22 females and 15 males) that were then analyzed for family relationships. Based on DNA fingerprints, the deduced family net revealed the fol-lowing facts: (i) First-order relatives possessed similarities from 50% to 90%, and similarities between unrelated indi-viduals or distant relatives were as high as 77%, indicating that the Tangjiahe pandas are characterized by high genetic similarity; (ii) 15 matings were identified and 5 ones oc-curred between close relatives, implying that there is poten-tial for inbreeding to impact the pandas; (iii) four mating pairs and 5 offspring presented long distance migrations, demonstrating the intra-reserve habitat is continuous; (iv) four pairs of full sibs (also female-male dyads) dispersed short distance and all of them gave birth to highly inbred offspring, reflecting long distance migration is vital for in-breeding avoidance; (v) 17 adult individuals dispersed short or moderate distance and formed three clusters on the land-scape, indicating that it is necessary to find out whether there is a negative factor impacting the pandas. | WAN Qiuhong FANG Shengguo LI Jianguo ZHANG Liming OU Weifu XIAN Fanghai CHEN Wanli | 2005 | Chinese Science Bulletin2005，50，17： | 3 |
| 6 | Screening of Anti-tumor Effective Extracts from Sedum bulbiferum Makino and HPLC Determination of Quercetin and Kaempferol in This Herbal Medicine显示文摘[Objectives] To investigate the anti-tumor activity of Sedum bulbiferum Makino in vitro,and establish a HPLC method for determination of quercetin and kaempferol in S. bulbiferum. [Methods] The inhibitory activities of different extracts and total flavonoids of S. bulbiferum on proliferation of three kinds of cancer cells( Hep G2,EC109,SW480) were tested by MTT assay. HPLC method for determination of quercetin and kaempferol in S. bulbiferum was established. [Results]The growth and proliferation of the three kinds of cancer cells were all significantly inhibited by ethyl acetate fraction and total flavonoids isolated from S. bulbiferum. With each extraction concentration increasing,stronger anti-tumor activity was found. The linear ranges of quercetin and kaempferol were 0. 03-0. 36 μg( R = 0. 999 9) and0. 08-0. 96 μg( R = 0. 999 9),and the average recoveries were 98. 90%( RSD = 1. 15%) and 98. 27%( RSD = 1. 70%),respectively.[Conclusions]S. bulbiferum has significant anti-tumor activity in vitro. The HPLC method established was accurate,reproducible,and could be used for quality control of this crude drug. | Liming MENG Xiangluan WAN Luyang LI Jing HU Pu CHEN Dingrong WAN | 2019 | Medicinal Plant2019，10，3： | 2 |
| 7 | Polyaniline nanotubes doped with sulfonated carbon nanotubes made via a self-assembly process 显示文摘 | Wei Zhixiang Wan Meixiang Lin Tong Dai Liming | 2003 | Adv Mater2003，15，： | 1 |
| 8 | Synthesis of ordered mesoporous CuO/CeOz composite via co-nanocasting replication method and its improved reactivity towards hydrogen显示文摘 | Wan Liming Cui Xiangzhi Chen Hangrong | 2010 | Materials Letters2010，64，： | 1 |
| 9 | Statistical root cause analysis of novel faults based on digraph models显示文摘 | Yiming Wan Fan Yang Ning Lv Haipeng Xu Hao Ye Weichang Li Peng Xu Liming Song Adam K. Usadi | 2013 | Chemical Engineering Research and Design2013，，1： | 1 |
| 10 | Processes of the displacement field change of the 2009 April 6 M_W6.3 L'Aquila earthquake using persistent scatterer and small baseline methods显示文摘Using a time series method that combines both the persistent scatterer and small baseline approaches,we analyzed 9 scenes Envisat ASAR data over the L’Aquila earthquake,and obtained a Shocke’s displacement field and its evolution processes.The results show that:(1)Envisat ASAR clearly detected the whole processes of displacement field of the L’Aquila earthquake,and distinct variations at different stages of the displacement field.(2)Preseismic creep displacement?displacement mutation when faulting?constantly slowed down after the earthquake.(3)The area of the strongest deformation and ground rupture was a low-lying oval depression region to the southeast.Surface faulting within a zone of about22 km 9 14 km,with an orientation of 135°,occurred along the NW-striking and SW-dipping Paganica-S.Demetrio normal fault.(4)In analyzing an area of about54 km 9 59 km,bounded by north–south axis to the epicenter,the displacement field has significant characteristics of a watershed:westward of the epicenter shows uplift with maximum of 130 mm in line-of-sight(LOS),and east of the epicenter was a region with 220 mm of maximum subsidence in the LOS,concentrating on the rupture zone,the majority of which formed in the course of faulting and subsequence. | Sanming Luo Liming Fu Shuang Zhu Qinglong He Wenni Wan Bo Yang | 2013 | Earthquake Science2013，26，5： | 0 |
| 11 | Hole‑Transport Management Enables 23%‑Efficient and Stable Inverted Perovskite Solar Cells with 84%Fill Factor显示文摘NiO_(x)-based inverted perovskite solar cells(PSCs)havepresented great potential toward low-cost,highly efficient and stablenext-generation photovoltaics.However,the presence of energy-levelmismatch and contact-interface defects between hole-selective contacts(HSCs)and perovskite-active layer(PAL)still limits device efficiencyimprovement.Here,we report a graded configuration based on bothinterface-cascaded structures and p-type molecule-doped compositeswith two-/three-dimensional formamidinium-based triple-halideperovskites.We find that the interface defects-induced non-radiativerecombination presented at HSCs/PAL interfaces is remarkably suppressedbecause of efficient hole extraction and transport.Moreover,astrong chemical interaction,halogen bonding and coordination bondingare found in the molecule-doped perovskite composites,whichsignificantly suppress the formation of halide vacancy and parasitic metallic lead.As a result,NiO_(x)-based inverted PSCs present a power-conversion-efficiency over 23%with a high fill factor of 0.84 and open-circuit voltage of 1.162 V,which are comparable to the best reported around 1.56-electron volt bandgap perovskites.Furthermore,devices with encapsulation present high operational stability over 1,200 h during T_(90) lifetime measurement(the time as a function of PCE decreases to 90%of its initial value)under 1-sun illumination in ambient-air conditions. | Liming Liu Yajie Ma Yousheng Wang Qiaoyan Ma Zixuan Wang Zigan Yang Meixiu Wan Tahmineh Mahmoudi Yoon‑Bong Hahn Yaohua Mai | 2023 | Nano-Micro Letters2023，15，8： | 0 |
| 12 | Synthesis of 2-Amino-2-deoxy-1,3-dithioidoglycosides via Organocatalytic Relay Glycosylation of 3-O-Acetyl-2-nitrogalactals显示文摘Idose-type glycosides have numerous biological activities and have been widely used as anticoagulant drugs and anti-infection drugs.Thioglycosides have enhanced stability for acid-mediated or enzymatic hydrolysis,and have a wide range of applications in glycobiology and drug development.Herein,we describe an efficient method for site-selective and stereoselective synthesis of potential bioactive 2-amino-2-deoxy-1,3-dithioidoglycosides via organocatalysis sequential C3-Ferrier rearrangement and Michael addition of 3-O-acetyl-2-nitrogalactals.Both stepwise and one-pot protocols were carried out and work well.This unique thio-glycosylation protocol highlighted the various advantages,including(i)mild reaction conditions;(ii)excellent site-selectivity and stereoselectivity,good to excellent yields;(iii)broad substrate scopes;(iv)being atom-economic and environmentally friendly;(v)the reactions can be scaled up. | Yongyong Wan Lei Deng Liming Wang Yuanhong Tu Hui Liu Jian-song Sun Qingju Zhang | 2023 | Chinese Journal of Chemistry2023，41，21： | 0 |
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