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| 1 | Osteogenic and antibacterial dual functions of a novel levofloxacin loaded mesoporous silica microspheres/nano-hydroxyapatite/ polyurethane composite scaffold显示文摘Lev/MSNs/n-HA/PU has been proved to be a novel scaffold material to treat bone defect caused by chronic osteomyelitis.We have previously identified that this material can effectively treat chronic osteomyelitis caused by Staphylococcus aureus in vivo.However,the potential mechanisms of antibacterial and osteogenic induction properties remain unclear.Thus,for osteogenesis property,immunohistochemistry,PCR,and Western blot were performed to detect the expression of osteogenic markers.Furthermore,flow cytometry and TUNEL were applied to analyze MC3T3-E1 proliferation and apoptosis.For antibacterial property,the material was co-cultivated with bacteria,bacterial colony forming units was counted and the release time of the effective levofloxacin was assayed by agar disc-diffusion test.Moreover,scanning electron microscope was applied to observe adhesion of bacteria.In terms of osteogenic induction,we found BMSCs adherently grew more prominently on Lev/MSNs/n-HA/PU.Lev/MSNs/n-HA/PU also enhanced the expression of osteogenic markers including OCN and COL1a1,as well as effectively promoted the transition from G1 phase to G2 phase.Furthermore,Lev/MSNs/n-HA/PU could reduce apoptosis of MC3T3-E1.Besides,both Lev/MSNs/n-HA/PU and n-HA/PU materials could inhibit bacterial colonies,while Lev/MSNs/n-HA/PU possessed a stronger antibacterial activities,and lower bacterial adhesion than n-HA/PU.These results illustrated that Lev/MSNs/n-HA/PU composite scaffold possess favorable compatibility in vitro,which induce osteogenic differentiation of MSCs,promote proliferation and differentiation of MC3T3-E1,and inhibit apoptosis.Moreover,clear in vitro antibacterial effect of Lev/MSNs/n-HA/PU was also observed.In summary,this study replenishes the potential of Lev/MSNs/n-HA/PU composite scaffold possess dual functions of anti-infection and enhanced osteogenesis for future clinical application. | Zhiping Kuang Guangming Dai Ruijie Wan Dongli Zhang Chen Zhao Cheng Chen Jidong Li Hongchen Gu Wei Huang | 2021 | Genes & Diseases2021，8，2： | 4 |
| 2 | Diversity of microbial plankton across the Three Gorges Dam of the Yangtze River,China显示文摘长江的三个峡水坝(TGD ) ,中国,在世界上是最大的灌溉和水力发电的工程工程之一。效果巨大人造象动物志和 macrophyte 上的 TGD 一样的工程是明显的,主要通过水动力学和流动模式的变化;然而,微生物怎么对如此的变化作出回应,是不太清楚的。这研究被瞄准在不同季节和地点在微生物引起的差异检验差别(在前面并且在 TGD 后面) 。另外,依附粒子、免费生活的社区之间的差别也被检验。在水列在后面并且在 TGD 前面的全部、潜在地活跃的微生物的社区结构与基于 DNA 、基于 RNA 的 16S rRNA 基因被分析在三个不同季节的种系发生的途径。16S rRNA 基因的克隆图书馆从提取 DNA 在扩大以后被准备并且为一些样品,在从提取 rRNA 准备 cDNA 以后。差别在不同季节并且在免费生活、依附粒子的社区之间在地点之间被观察。细菌并且 archaeal 社区比在冬季在夏天是更多样的,由于在夏天的更高滋养的层次和更温暖的温度比在冬季。依附粒子的微生物比免费生活的社区更多样,可能因为在粒子的更高滋养的层次和异构的 geochemical 微型环境。在细菌的社区结构的空间变化被观察,即,在 TGD 后面的水水库(在上游) 比在水坝前面招待了更多样的细菌的人口(下游) ,因为沉积和水从的多样的来源对水库在上游。这些结果在水坝建设影响的河生态系统为我们对环境变化的微生物引起的社区的回答的理解有重要含意。 | Shang Wang Raymond M. Dong Christina Z. Dong Liuqin Huang Hongchen Jiang Yuli Wei Liang Feng Deng Liu Guifang Yang Chuanlun Zhang Hailiang Dong | 2012 | Geoscience Frontiers2012，3，3： | 4 |
| 3 | Extraction, detection, and profiling of serum biomarkers using designed Fe3O4@SiO2@HA core-shell particles显示文摘 | Chandrababu Rejeeth Xuechao Pang Ru Zhang Wei Xu Xuming Sun Bin Liu Jiatao Lou Jingjing Wan Hongchen Gu Wei Yan Kun Qian | 2018 | Nano Research2018，11，1： | 2 |
| 4 | Connexin 43 Reverses Malignant Phenotypes of Glioma Stem Cells by Modulating E‐Cadherin显示文摘 | Shi‐CangYu Hua‐LiangXiao Xue‐FengJiang Qing‐LiangWang YanLi Xiao‐JunYang Yi‐FangPing Jiang JieDuan Jian‐YongJiang Xian‐ZongYe Sen‐LinXu Yang‐HongXin Xiao‐HongYao Jian‐HongChen Wei‐HuaChu WeiSun BingWang Ji MingWang XiaZhang Xiu‐WuBian | 2012 | STEM CELLS2012，，2： | 1 |
| 5 | Development of lateral flow immunoassay system based on superparamagnetic nanobeads as labels for rapid quantitative detection of cardiac troponin I显示文摘 | QuanFu Xu Hong Xu Hongchen Gu JingBo Li Yanyan Wang Meng Wei | 2009 | Materials Science & Engineering C2009，，3： | 1 |
| 6 | Effects of Pulsed Electromagnetic Fields on Bone Mass and Wnt/β-Catenin Signaling Pathway in Ovariectomized Rats显示文摘 | Jun Zhou Hongchen He Lin Yang Shiju Chen Hua Guo Lu Xia Huifang Liu Yuxi Qin Chuan Liu Xiaofei Wei Yujing Zhou Chengqi He | 2012 | Archives of Medical Research2012，，4： | 1 |
| 7 | Surgical treatment of phyllodes tumors of the breast: Retrospective review of 172 cases显示文摘 | Wei‐HongChen Shih‐PingCheng Chi‐YuanTzen Tsen‐LongYang Kuo‐ShyangJeng Chien‐LiangLiu Tsang‐PaiLiu | 2005 | J Surg Oncol2005，，3： | 1 |
| 8 | Endovascular treatment for basilar artery occlusion:a meta-analysis显示文摘Acute basilar artery occlusion(BAO)may lead to severe disability or death in about 70%of patients.12 Previous studies have estab-lished endovascular treatment(EVT)as the standard treatment for patients with acute anterior circulation occlusions.3-9 However,the ideal effective treatment for acute BAO remains controversial. | Jiawen Xu Xi Chen Shidong Chen Wenjie Cao Hongchen Zhao Wei Ni Yanrong Zhang Chao Gao Yuxiang Gu Xin Cheng Yi Dong Qiang Dong | 2023 | Stroke & Vascular Neurology2023，8，1： | 0 |
| 9 | Digitalization Dividends显示文摘Internet of Things(IoT)is an emerging information technology,while fishery is a traditional agricultural industry.The two seem to be incompatible.But for Shen Yunjian,who has been raising fish for 14 years,the IoT has brought him enorm ous benefits.Shen,in his 50s,and his wife have contracted a 70-mu(4.67-hectare)fish pond in Quxi Village,Deqing County in the eastern province of Zhejiang.Like most fishermen,they adopted the traditional open-air fishpond farming model,relying on experience to raise fish. | Wei Hongchen | 2020 | ChinAfrica2020，12，2： | 0 |
| 10 | Jobs of the Future显示文摘Tang Yi hadn’t planned to celebrate his birthday this year.The deliveryman was rushing around Beijing ensuringhis customers received their online orders during the restricted days of the novel coronavrius disease (COVID-19) epidemic.There was no time to do anything else. | Xia Yuanyuan Wei Hongchen | 2020 | Beijing Review2020，63，35： | 0 |
| 11 | Effects of carrier-attached biofilm on oxygen transfer efficiency in a moving bed biofilm reactor显示文摘有不同搬运人充满比率从 40% ~ 60%的三实验室规模移动床 biofilm 反应堆(MBBR ) 被用来在氧转移效率上学习依附搬运人的 biofilm 的效果。在这研究,我们在降级的化学的氧需求和氨评估了三 MBBR 的表演。三个反应堆在 60 L 的空气流动率移开超过 95% NH 4+-N ???? | Yanling WEI Xunfei YIN Lu QI Hongchen WANG Yiwei GONG Yaqian LUO | 2016 | Frontiers of Environmental Science & Engineering2016，10，3： | 0 |
| 12 | Smart and Strong显示文摘After participating in Bauma 2019,the largest construction machinery trade fair in the world held every three years in Munich,Germany,Case Corp.,a major U.S.manufacturer of construction and agricultural equipment wasted no time and headed straight to China for an other major exhibition.It was the first time Case had participated in the Chinese exhibition and also the first time Changsha,capital city of central China's Hunan Provinee,had hosted such a big event.The Changsha In ter national Construction Equipment Exhibition,held on May 15-18,brought together the giants in the industry,with 1,150 companies.including 24 world leaders,displaying their latest products. | Wei Hongchen Xia Yuanyuan | 2019 | Beijing Review2019，62，22： | 0 |
| 13 | On the Bund and On the Mend显示文摘She wears a white coat,speaks fluent Chinese and diagnoses patients with the assistance of traditional Chinese medicine(TCM).A German physician working at the Body and Soul Clinic in Shanghai's Huangpu District,Doris Rathgeber,born in Düsseldorf in 1966,has been familiar with TCM for more than 20 years.She has practiced mainly in Shanghai and dedicates her professional life to promoting China's centuries-old medical system around the globe. | Wei Hongchen | 2021 | Beijing Review2021，64，31： | 0 |
| 14 | Baking Generosity A German couple finds a place helping hearing-impaired children显示文摘Bach’s Bakery on Xiangchun Road in Changsha,capital of central China’s Hunan Province,opens at eight o’clock in the morning every day and provides customers with German bread straight from the oven.The modest bakery looks similar to other shops on the winding lane; | Wei Hongchen | 2018 | Beijing Review2018，61，34： | 0 |
| 15 | Expert consensus on odontogenic maxillary sinusitis multi-disciplinary treatment显示文摘Odontogenic maxillary sinusitis (OMS) is a subtype of maxillary sinusitis (MS). It is actually inflammation of the maxillary sinus that secondary to adjacent infectious maxillary dental lesion. Due to the lack of unique clinical features, OMS is difficult to distinguish from other types of rhinosinusitis. Besides, the characteristic infectious pathogeny of OMS makes it is resistant to conventional therapies of rhinosinusitis. Its current diagnosis and treatment are thus facing great difficulties. The multi-disciplinary cooperation between otolaryngologists and dentists is absolutely urgent to settle these questions and to acquire standardized diagnostic and treatment regimen for OMS. However, this disease has actually received little attention and has been underrepresented by relatively low publication volume and quality. Based on systematically reviewed literature and practical experiences of expert members, our consensus focuses on characteristics, symptoms, classification and diagnosis of OMS, and further put forward multidisciplinary treatment decisions for OMS, as well as the common treatment complications and relative managements. This consensus aims to increase attention to OMS, and optimize the clinical diagnosis and decision-making of OMS, which finally provides evidence-based options for OMS clinical management. | Jiang Lin Chengshuo Wang Xiangdong Wang Faming Chen Wei Zhang Hongchen Sun Fuhua Yan Yaping Pan Dongdong Zhu Qintai Yang Shaohua Ge Yao Sun Kuiji Wang Yuan Zhang Mu Xian Ming Zheng Anchun Mo Xin Xu Hanguo Wang Xuedong Zhou Luo Zhang | 2024 | International Journal of Oral Science2024，16，1： | 0 |
| 16 | German Überzeugt in China显示文摘In this exclusive interview,Michael Schumann,chairman of the Board of the German Federal Association for Economic Development and Foreign Trade,discusses Sino-German trade relations and the“out-of-proportion”debate on Xinjiang. | WEI HONGCHEN | 2024 | China Today2024，73，4： | 0 |
| 17 | Migration of Cr_2O_7^(2-) and Butanone in Soil and Groundwater System After the Tianjin Port 8·12 Explosion显示文摘After the Tianjin Port 8·12 explosion, an enormous amount of potassium dichromate(K_2Cr_2O_7) and butanone(CH_3COCH_2CH_3) leaked into the coastal soil–groundwater system, which potentially threatened the environment and human health. Determining the transport process of hazards is necessary to establish guidelines for remediating the contaminated area. This work aims to investigate the migration of potassium dichromate and butanone in the coastal soil-groundwater system through a coupling unsaturated–saturated numerical model, incorporating the HYDRUS model into the MODFLOW/MT3D model. In the unsaturated zone, two-dimensional HYDRUS model was applied, and its recharge flux at the bottom boundary was utilized as the input of MODFLOW/MT3D model in the saturated zone. Results showed that Cr_2O_7^(2-) migrated much faster than butanone in the unsaturated zone and reached the water table in about 1 year. In comparison, butanone was unlikely to enter the aquifer even 5 years later with a migration depth of about 2.2 m. Driven by groundwater, the Cr_2O_7^(2-) that entered the aquifer migrated about 161 m toward southeast 5 years later. In the saturated zone, the contamination plume covered mainly the southeast area due to the groundwater flow direction. | Liyan Liu Shaopan Liang Hongchen Liu Wei Tan Guorui Zhu | 2018 | Transactions of Tianjin University2018，24，6： | 0 |
| 18 | Studying China显示文摘A forum on China studies reviews the country’s development over the past 70 years and its worldwide benefits Nicholas Platt, U.S. diplomat and President Emeritus of the Asia Society, can’t remember how many times he has been to China. He thinks it’s got to be more than 60times. | Wei Hongchen | 2019 | Beijing Review2019，62，39： | 0 |
| 19 | Wind Advantage显示文摘Leo Carolus is a lucky young man in Luderitz Town of Karas in south west Namibia as he has a stable job near his home.“Thanks to the Ombepo Wind Farm, I can now work so close to my home, which was previously unimaginable for me,” he said. Up on the mountain not far from his home, three wind turbines developed and installed by China s Hunan-based XEMC Windpower Co. Ltd. have been operating for two years, which Carolus can see even from his home. | Wei Hongchen | 2019 | ChinAfrica2019，11，7： | 0 |
| 20 | Digitalization Dividends显示文摘Internet of Things(IoT)is an emerging information technology,while fishery is a traditional agricultural industry.The two seem to be incompatible.But for Shen Yunjian,who has been raising fish for 14years,the loT has brought him enormous benefits. | Wei Hongchen | 2020 | Beijing Review2020，63，2： | 0 |
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