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| 1 | Optimization design and test of rice plug seedling transplanting mechanism of planetary gear train with incomplete eccentric circular gear and non-circular gears显示文摘In order to solve the problem of the high-speed mechanized transplanting of rice plug seedlings,the design requirements of transplanting mechanism for rice plug seedlings were analyzed and a kind of rice plug seedling transplanting mechanism of planetary gear train based on the drive with incomplete eccentric circular gear and non-circular gears was designed innovatively.The laboratory kinematics was examined.The working principle of the transplanting mechanism for rice plug seedlings was studied,kinematics analysis of the transplanting mechanism was carried out and its kinematic model was set up.A human-computer interaction optimization method was used to optimize the parameters of the transplanting mechanism.The computer aided analysis and optimization software of the transplanting mechanism based on Visual Basic 6.0 was developed.Through analyzing the influence of design variables on the optimization objectives of the transplanting mechanism,a set of parameters of the transplanting mechanism which meet the requirements of transplanting trajectory and posture for transplanting rice seedlings were obtained by means of human-computer interaction.The structure of the transplanting mechanism was designed according to this set of parameters,and its virtual prototype and physical prototype were set up and manufactured,respectively.The kinematic simulation test and high-speed photography kinematic test of the transplanting mechanism were conducted to obtain its kinematic performances,such as transplanting trajectory and posture.The results of bench test,simulation analysis and theoretical analysis were almost in agreement,which verified the correctness of the theoretical model and design results of the transplanting mechanism,indicating that the optimized transplanting mechanism can satisfy the requirements of transplanting rice seedlings and be applied in the rice plug seedling transplanter. | Ye Bingliang Yi Weiming Yu Gaohong Gao Yang Zhao Xiong | 2017 | International Journal of Agricultural and Biological Engineering2017，10，6： | 31 |
| 2 | Ar-Ar geochronology of Late Mesozoic volcanic rocks from the Yanji area, NE China and tectonic implications显示文摘Ar-Ar dating results of late Mesozoic-Cenozoic volcanic rocks from the Yanji area, NE China provide a new volcano-sedimentary stratigraphic framework. The previously defined “Triassic-Jurassic” volcanic rocks (including those from Sanxianling, Tuntianying, Tianqiaoling and Jingouling Fms.) were erupted during 118―106 Ma, corresponding to Early Cretaceous. The new eruption age span is slightly younger than the main stage (130―120 Ma) of the extensive magmatism in the eastern Central Asian Orogenic Belt and its adjacent regions. Subduction-related adakites occurring in the previously defined Quanshuicun Fm. were extruded at ca. 55 Ma. Based on these new Ar-Ar ages, the late Mesozoic to Palaeocene volcano-sedimentary sequences is rebuilt as: Tuopangou Fm., Sanxianling/Tuntianying Fm. (118―115 Ma), Malugou/Tianqiaoling Fm. (K1), Huoshanyan/Jingouling Fm. (108―106 Ma), Changcai Fm. (K2), Quanshuicun Fm. (~55 Ma) and Dalazi Fm. Our results suggest that subduction of the Pa- laeo-Pacific Ocean beneath the East Asian continental margin occurred during 106 to 55 Ma, consistent with the paleomagnetic observations and magmatic records which indicated that the Izanagi-Farallon ridge subduction beneath the southwestern Japan took place during 95―65 Ma. | LI ChaoWen GUO Feng FAN WeiMing GAO XiaoFeng | 2007 | Science China Earth Sciences2007，50，4： | 15 |
| 3 | New Trends in Intelligent Manufacturing显示文摘Intelligent manufacturing technology has become a major trend in the development of the manufacturing industry around the world,and is being studied and applied by numerous industrially developed countries.For example,the United States has proposed an intelligent manufacturing layout based on the Industrial Internet and the‘‘New Generation of Robots”;Germany has proposed the Industry 4.0 initiative to boost the competitiveness of the manufacturing industry through intelligent manufacturing;and the European Union(EU),Japan,Korea,China,and other large manufacturing countries have put forward corresponding strategies for the development of intelligent manufacturing.Clearly,intelligent manufacturing has become an important direction in the development of the manufacturing industry. | Liang Gao Weiming Shen Xinyu Li | 2019 | Engineering2019，5，4： | 14 |
| 4 | BLT1 in dendritic cells promotes Th1/Th17 differentiation and its deficiency ameliorates TNBS-induced colitis显示文摘Leukotriene B4(LTB4)synthesis is enhanced in the colonic mucosa in patients with inflammatory bowel disease(IBD).BLT1,a highaffinity receptor for LTB4,exhibits no effect on the progression of dextran sodium sulfate(DSS)-induced colitis,which mostly relies on innate immunity.Here,we reported that BLT1 regulates trinitrobenzene sulfonic acid(TNBS)-induced colitis,which reflects CD4+T-cell-dependent adaptive immune mechanisms of IBD.We found that BLT1 signaling enhanced the progression of colitis through controlling the production of proinflammatory cytokines by dendritic cells(DCs)and modulating the differentiation of Th1 and Th17.BLT1−/−mice displayed an alleviated severity of TNBS-induced colitis with reduced body weight loss and infiltrating cells in the lamina propria.BLT1 deficiency in DCs led to reduced production of proinflammatory cytokines,including IL-6,TNF-α,and IL-12,and these results were further confirmed via treatment with a BLT1 antagonist.The impaired cytokine production by BLT1−/−DCs subsequently led to reduced Th1 and Th17 differentiation both in vitro and in vivo.We further performed a conditional DC reconstitution experiment to assess whether BLT1 in DCs plays a major role in regulating the pathogenesis of TNBS-induced colitis,and the results indicate that BLT1 deficiency in DCs also significantly reduces disease severity.The mechanistic study demonstrated that BLT1-regulated proinflammatory cytokine production through the Gαiβγsubunit-phospholipase Cβ(PLCβ)-PKC pathway.Notably,we found that treatment with the BLT1 antagonist also reduced the production of proinflammatory cytokines by human peripheral blood DCs.Our findings reveal the critical role of BLT1 in regulating adaptive immunity and TNBS-induced colitis,which further supports BLT1 as a potential drug target for adaptive immunity-mediated IBD. | Jinfeng Zhou Weiming Lai Wanjie Yang Juping Pan Hu Shen Yingying Cai Cuixia Yang Ningjia Ma Yue Zhang Ru Zhang Xin Xie Zhongjun Dong Yuan Gao Changsheng Du | 2018 | Cellular & Molecular Immunology2018，15，12： | 9 |
| 5 | WO_3/ZrO_2 Strong Acid as a Catalyst for the Decomposition of Chlorofluorocarbon (CFC-12)显示文摘 | HUA Weiming ZHANG Feng MA Zhen TANG Yi GAO Zi | 2000 | Chemical Research in Chinese Universities2000，16，2： | 7 |
| 6 | Diallyl trisulfide induces apoptosis and inhibits proliferation of A549 cells in vitro and in vivo显示文摘肺癌症是在整个世界的癌症相关的死亡的领先的原因。在最近的年里,肺的腺癌在频率超过了有鳞的房间癌并且是在许多国家的肺癌症的占优势的形式。流行病学的调查显示出在消费和死亡从许多癌症评估的大蒜(瞀或蒜之类 sativum ) 之间的一种反的关系。Diallyl trisulfide (DATS ) 是导出大蒜的混合物之一(是也知道:organosulfer 混合物,振荡) 。DATS 能导致 apoptosis 并且禁止许多癌症细胞线的生长。我们的学习证明 DATS 导致的 apoptotic 事件是通过导致了 Bax/Bcl-2 和 caspase-3, -8, 和 -9 的活动的比率的起来规定的 anti-apoptotic Bcl-2 的重要减少的线粒体依赖者 caspase 串联。最后, DATS 导致了 apoptosis 并且在一个集中依赖者和时间依赖者举止禁止了增长。由与 A549 异种皮移植建立女 BALB/c 裸体老鼠的一个动物模特儿,没有与控制组相比引起重量损失或任何另外的副作用,而且,我们在裸体老鼠发现 DATS 的那口头的 gavage A549 异种皮移植的显著地延迟的生长。在 vitro 并且在 vivo 的所有证据建议 DATS 能是理想的反癌症药。 | Wenjun Li Hui Tian Lin Li Shuhai Li Weiming Yue Zhitao Chen Lei Qi Wensi Hu Yingchao Zhu Bin Hao Cun Gao Libo Si Fei Gao | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 6 |
| 7 | Effects of fractal surface on rheological behavior and combustion kinetics of modified brown coal water slurries显示文摘 | Zhifang Gao Shuquan Zhu Mingdong Zheng ZhaojinWu Huihong Lu Weiming Liu | 2015 | International Journal of Coal Science & Technology2015，2，3： | 6 |
| 8 | Qiguiyishen decoction reduced the accumulation of extracellular matrix in the kidneys of rats with adriamycin-induced nephropathy显示文摘OBJECTIVE: To investigate the effect of Qiguiyishen decoction(QGYS) on the severity of nephropathy.METHODS: Twenty-four rats were randomly divided into four groups(Ⅰ, Ⅱ, Ⅲ, Ⅳ) according to the random number table. Group Ⅰ as control group did not establish nephropathy model. Groups Ⅱ,Ⅲ, and Ⅳ were intravenously administered Adriamycin(7.5 mg/kg) through the tail vein to establish nephropathy model. QGYS was prepared with the extracts of Huangqi(Radix Astragali Mongolici),Danggui(Radix Angelicae Sinensis),Niuxi(RadixAchyran-this Bidentatae), and Chuanxiong(Rhizoma Chuanxiong).Group Ⅳ was administered QGYS (2mL·kg-1·d-1), group Ⅲ was administered benazepril(10 mL·kg-1·d-1), and group Ⅰ, Ⅱ was administered water(2mL·kg-1·d-1)once daily for eight weeks.RESULTS: QGYS reduced the excretion of urinary protein and N-acetyl-β-D-glucosaminidase and alleviated the accumulation of extracellular matrix(ECM) in renal tissue. Additionally, QGYS effectively regulated the levels of transforming growth factor,tissue inhibitor of matrix metalloproteinase, and matrixmetalloprote in asesin the kidney of the rats.CONCLUSION:QGYS may reduce the accumulation of ECM in the kidneys of rats with Adriamycin-induced nephropathy. | Minggang Wei Wei Sun Weiming He Li Ni Xiaofeng Cai Zongqi Cheng Kun Gao Fengling Li Lin Chen Xinping Zhang | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 4 |
| 9 | Research and perspectives on geomorphology in China: Four decades in retrospect显示文摘Geomorphology is one of the main subdisciplines of geography.The research achievements and prospects in geomorphology have received considerable attention for a long time.In this paper,a general retrospect of geomorphologic research in China over the past 60 years was firstly addressed,especially the research progress during the last 40 years.Based on a summary of experience and a tendency of development,perspectives of geomorphologic research direction in the future were provided.It is concluded that the discipline of geomorphology has made great progress in the aspects of geomorphologic types,regionalization,as well as their subdisciplines such as dynamic geomorphology,tectonic geomorphology,climatic geomorphology,lithological geomorphology,palaeogeomorphology.We believe that persisting in the unity principle between morphological and genetic types would be conductive for the development of traditional landforms and integrated landforms.In addition,five perspectives aim to enhance China’s geomorphologicl research capacity were proposed.They are:(1)strengthening the research of basic geomorphologic theory and the research of integrated geomorphology to expand the research space;(2)focusing more on the research of geomorphologic structure and geomorphologic function to improve the application ability of geomorphology;(3)constructing a comprehensive resource,environmental,and geomorphologic information system and building a sharing platform to upgrade the intelligent information industry of geomorphology;(4)putting more efforts on the research of coastal geomorphology and marine geomorphology to assist the transformation of China from a maritime country to an ocean power;and(5)cultivating talents and constructing research teams to maintain a sustainable development of China’s geomorphologic research. | CHENG Weiming LIU Qiangyi ZHAO Shangmin GAO Xiaoyu WANG Nan | 2017 | Journal of Geographical Sciences2017，27，11： | 3 |
| 10 | Oxidative Dehydrogenation of 1-Butene to 1,3-Butadiene Using CO2 over Cr-SiO2 Catalysts Prepared by Sol-gel Method显示文摘 | GAO Biao LUO Yajun MIAO Changxi YUE Yinghong YANG Weimin HUA Weiming GAO Zi | 2018 | Chemical Research in Chinese Universities2018，34，4： | 2 |
| 11 | HPLC and GC methods development for the analysis of key intermediate for synthesis of dicamba显示文摘The microreactor based hydroxylation process of 1,2,4-trichlorobezene for producing 2,5-dichlorphenol,the key intermediate of dicamba,is energy efficient and cost effective.But the 2,5-dicholorphneol is present in a mixed state after production.The reaction mixture contained the main by-product 2,4-dichlorophneol,low-content by-product 3,4-dichlorophneol,and other impurities.The difficulty in separation and analysis limits the application of this process widely.The current work aimed at establishing effective analysis methods by gas chromatography(GC)and high performance liquid chromatography(HPLC).The GC method was not able to separate 2,5-dichlorophenol and 2,4-dichlorophenol completely,but the developed HPLC method worked efficiently.The linear correlation coefficients of 2,5-dichlorophenol and 2,4-dichlorophenol were both higher than 0.999,and the average recovery was 100.33% for 2,5-dichlorophenol and 100.13% for 2,4-dichlorophenol,respectively.The relative standard deviations from precision tests were both less than 1%.The contents of 2,5-dichlorophenol and 2,4-dichlorophenol were determined with external standard method.The HPLC method has the advantages of simple operation,good separation efficiency,high accuracy and precision,and was successfully applied for both qualitative and quantitative analysis of 2,5-dichlorophenol and 2,4-dichlorophenol of the sample solution. | Zhenming Zhang He Zhao Xiaohui Wang Weiming Ni Fengsheng Gao Jianrong Wang Minjin Liu Yongli Li | 2021 | Chinese Journal of Chemical Engineering2021，34，5： | 2 |
| 12 | Down-regulation of MTA1 protein leads to the inhibition of migration, invasion, and angiogenesis of non-small-cell lung cancer cell line显示文摘联系转移的蛋白质 1 (MTA1 ) 高表示在许多人的好攻击的肿瘤被检测了并且在象侵略,转移,和 angiogenesis 那样的恶意的生物行为起重要作用。然而,在调整 non-small-cell 肺癌症(NSCLC ) 的恶意的行为的 MTA1 蛋白质的特定的角色和机制房间仍然保持不清楚。阐明 MTA1 蛋白质的详细函数,我们下面调整在由在 vitro 的 RNA 干扰(RNAi ) 的 NSCLC 房间线的 MTA1 蛋白质表达式,并且发现 MTA1 蛋白质的下面规定显著地禁止了 95D 房间的移植和侵略潜力。进一步的研究表明 MTA1 蛋白质的下面规定显著地减少了矩阵 metalloproteinase-9 的活动,它能是为 95D 房间移植和侵略的抑制负责的机制。另外,试管形成试金证明 MTA1-siRNA 95D 房间的调节媒介导致的完全的试管的数字比 95D 房间的显著地小。这些调查结果证明那 MTA1 蛋白质在调整 95D 房间的迁居,侵略,和 angiogenesis 潜力起重要作用,由 RNAi 建议那条 MTA1 蛋白质下面规定可能是一条新奇治疗学的途径禁止 NSCLC 的前进。 | Shuhai Li Hui Tian Weiming Yue Lin Li Cun Gao Libo Si Wenjun Li Wensi Hu Lei Qi Ming Lu | 2013 | Acta Biochimica et Biophysica Sinica2013，45，2： | 2 |
| 13 | Restricted peri-operative fluid administration adjusted by serum lactate level improved outcome after major elective surgery for gastrointestinal malignancy显示文摘 | Yu WenKui Li Ning Gong JianFeng Li WeiQin Tang ShaoQiu Tong Zhihui Gao Tao Zhang JuanJuan Xi FengChan Shi Hui Zhu WeiMing Li Jie-Shou | 2010 | Surgery2010，，4： | 2 |
| 14 | Online Adaboost- Based Parameterized Meth- ods for Dynamic Distributed Network Intrusion Detection 显示文摘 | Weiming Hu Jun Gao Yanguo Wang Ou Wu May- bank S | 2014 | Cybernetics IEEE Transactions on2014，，1： | 1 |
| 15 | Acidity enhancement of SBA mesoporous molecular sieve by modification with SO4^2-/ZrO2 显示文摘 | Hua Weiming Yue Yinghong Gao Zi | 2001 | J Mol Catal A: Chemical2001，170，： | 1 |
| 16 | Hydrogenation of Methyl Benzoate over Mn/Al Catalysts: Comparison among Catalyst Preparation Routes显示文摘 | Aimin Chen Hualong Xu Weiming Hua Wei Shen Yinghong Yue Zi Gao | 2005 | Topics in Catalysis (-)2005，，1： | 1 |
| 17 | Higher rates of nitrogen fertilization decrease soil enzyme activities, microbial functional diversity and nitrification capacity in a Chinese polytunnel greenhouse vegetable land显示文摘 | Weishou Shen Xiangui Lin Weiming Shi Ju Min Nan Gao Huayong Zhang Rui Yin Xinhua He | 2010 | Plant and Soil (-)2010，，1： | 1 |
| 18 | Acidity enhancement of SBA mesoporous molecular sieve by modification with SO42-/ZrO2 显示文摘 | Hua Weiming Yue Yinghong Gao Zi | 2001 | J Mol Catal A: Chemical2001，170，： | 1 |
| 19 | Active label-denoising algorithm based on broad learning for annotation of machine health status显示文摘Deep learning has led to tremendous success in machine maintenance and fault diagnosis.However,this success is predicated on the correctly annotated datasets.Labels in large industrial datasets can be noisy and thus degrade the performance of fault diagnosis models.The emerging concept of broad learning shows the potential to address the label noise problem.Compared with existing deep learning algorithms,broad learning has a simple architecture and high training efficiency.An active label denoising algorithm based on broad learning(ALDBL)is proposed.First,ALDBL captures the embedded representation from the time-frequency features by a recurrent memory cell.Second,it augments wide features with a sparse autoencoder and projects the sparse features into an orthogonal space.A proposed corrector then iteratively changes the weights of source examples during the training and corrects the labels by using a label adaptation matrix.Finally,ALDBL finetunes the model parameters with actively sampled target data with reliable pseudo labels.The performance of ALDBL is validated with three benchmark datasets,including 30 label denoising tasks.Computational results demonstrate the effectiveness and advantages of the proposed algorithm over the other label denoising algorithms. | LIU GuoKai SHEN WeiMing GAO Liang KUSIAK Andrew | 2022 | Science China(Technological Sciences)2022，65，9： | 1 |
| 20 | Transgenic tomato overexpressing ath-miR399d has enhanced phosphorus accumulation through increased acid phosphatase and proton secretion as well as phosphate transporters显示文摘 | Nan Gao Yanhua Su Ju Min Weishou Shen Weiming Shi | 2010 | Plant and Soil (-)2010，，1： | 1 |
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