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| 1 | Mitochondrial DNA A1555G mutation screening using a testing kit method and its significance in preventing aminoglycoside-related hearing loss显示文摘To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory hearing loss patients were tested for 1555A→G mutation using a new compact testing kit, which allows clear distinction between wild type and 1555 A→G mutated mtDNAs. Results Nineteen subjects among the 546 patients (3.48%) were found to carry mtDNA A1555G mutation. The results were confirmed by sequencing in an ABI 3100 Avant sequencer. Conclusions Maternal inherited deafness families are a frequently seen in outpatient group. The detection of mtDNA 1555 A→G mutation with a low cost, ready to use detection kit is needed and suitable in China for large scale screening and preventive testing before usage of aminoglycoside antibiotics. | LIU Xin,1 DAI Pu,1* HUANG Deliang,1 YUAN Huijun,1 LI Weiming,1 YU Fei,1 ZHANG Xin,1 KANG Dongyang,1 CAO Juyang,1 YANG Weiyan,1 HAN Dongyi,1 JIN Zhengce2, GUAN Minxin3 1. Department of Otolaryngology, Chinese PLA General Hospital, Beijing, China2. Weihai Aomaier Gene Technological CO.,LTD.,Weihai,Shandong 264200, China.3. Division and Program in Human Genetics and Center for Hearing and Deafness Research, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA | 2006 | Journal of Otology2006,1,1: | 7 |
| 2 | Extremely low penetrance of deafness associated with the mitochondrial 12S rRNA mutation in 16 Chinese families: Implication for early detection and prevention of deafness显示文摘 | Pu Dai Xin Liu Dongyi Han Yaping Qian Deliang Huang Huijun Yuan Weiming Li Fei Yu Ruining Zhang Hongyan Lin Yong He Youjun Yu Quanzhu Sun Huaiyi Qin Ronghua Li Xin Zhang Dongyang Kang Juyang Cao Wie-Yen Young Min-Xin Guan | 2005 | Biochemical and Biophysical Research Communications2005,,1: | 2 |
| 3 | Hydrogen embrittlement of Pt3Zr compound from first-principles 显示文摘 | Yong Pan Weiming Guan Ming Wen | 2014 | Journal of Alloys and Compounds2014,,585: | 1 |
| 4 | Pt-Ru Catalysts Prepared by a Modified Polyol Process for Direct Methanol Fuel Cells显示文摘Supported PtRu/C catalysts used in direct methanol fuel cells (DMFCs) were prepared by a new modified polyol method. Transmission electron microscopy (TEM), X-ray diffraction (XRD) and cyclic voltammograms (CVs) were carried out to characterize the morphology, composition and the electrochemical properties of the PtRu/C catalyst. The results revealed that the PtRu nanoparticles with small average particle size (≈2.5 nm), and highly dispersed on the carbon support. The PtRu/C catalyst exhibited high catalytic activity and anti poisoned performance than that of the JM PtRu/C. It is imply that the modified polyol method is efficient for PtRu/C catalyst preparation. | ZHANG Junmin ZHU Fangfang ZHANG Kunhua LIU Weiping GUAN Weiming | 2012 | 贵金属2012,33,A01: | 1 |
| 5 | HIV Incidence and Associated Factors in a Cohort of Men Who Have Sex With Men in Nanjing, China显示文摘 | Haitao Yang Chun Hao Xiping Huan Hongjing Yan Wenhui Guan Xiaoqin Xu Min Zhang Weiming Tang Na Wang Joseph T. F. Lau | 2010 | Sexually Transmitted Diseases2010,,4: | 1 |
| 6 | Application of the Finite Element Method in the Glass Fiber Bushing Research显示文摘Design and optimization of bushing at present mainly use the traditional experience method.The relevant research that adopts computer simulation to carry on the operation behavior of the bushing has appeared in recent years.How to use the finite element method to research bushing was introduced in the article.Physics fields and many relevant parameters of one real bushing were calculated.Through the results of calculation,it indicate that the finite element method is very useful in bushing research of designing and optimizing. | CHEN Song LU Jiansheng GUAN Weiming ZHANG Kunhua PAN Yong TAN Zhilong XIA Lu | 2012 | 贵金属2012,33,A01: | 1 |
| 7 | Brain-Controlled Multi-Robot at Servo-Control Level Based on Nonlinear Model Predictive Control显示文摘Using a brain-computer interface(BCI)rather than limbs to control multiple robots(i.e.,brain-controlled multi-robots)can better assist people with disabilities in daily life than a brain-controlled single robot.For example,one person with disabilities can move by a brain-controlled wheelchair(leader robot)and simultaneously transport objects by follower robots.In this paper,we explore how to control the direction,speed,and formation of a brain-controlled multi-robot system(consisting of leader and follower robots)for the first time and propose a novel multi-robot predictive control framework(MRPCF)that can track users'control intents and ensure the safety of multiple robots.The MRPCF consists of the leader controller,follower controller,and formation planner.We build a whole brain-controlled multi-robot physical system for the first time and test the proposed system through human-in-the-loop actual experiments.The experimental results indicate that the proposed system can track users'direction,speed,and formation control intents when guaranteeing multiple robots’safety.This paper can promote the study of brain-controlled robots and multi-robot systems and provide some novel views into human-machine collaboration and integration. | Zhenge Yang Luzheng Bi Weiming Chi Haonan Shi Cuntai Guan | 2022 | Complex System Modeling and Simulation2022,2,4: | 0 |
| 8 | Aqueous Solution Preparation of Ruthenium Nanoparticles Using Ammonium Formate as the Reducing Agent显示文摘Ruthenium, one of the platinum group metals, has drawn much attention due to its catalytic behavior, hardness, electrical conductivity and density. Ruthenium particles are usually prepared on a small scale by the polyol process, however, the size of the obtained ruthenium nanoparticles is most below 10 nm. In this work, ruthenium particles about 200 nm in diameter were obtained in aqueous solution by using ammonium formate as the reducing agent. To have a better control of particle's size and shape, the effects of PVP, mixing mode, reaction temperature, solution pH and calcination temperature were investigated. | LIU Shaohong CHEN Jialin GUAN Weiming BI Jun CHEN Nanguang CHEN Dengquan LIU Manmen SUN Xudong | 2012 | 贵金属2012,33,A01: | 0 |