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    题名 作者 年代 出处 被引量
1Antigen-presenting effects of effector memory Vγ9Vδ2 T cells in rheumatoid arthritis显示文摘Chaoying Hu Liu Qian Yi Miao Qiuyu Huang Ping Miao Ping Wang Qiwen Yu Hong Nie Jiying Zhang Dongyi He Rong Xu Xuehua Chen Bingya Liu Dongqing Zhang 2012Cellular & Molecular Immunology2012,9,3:18
2De novo mutation in ATP6V1B2 impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome显示文摘Yongyi Yuan Jianguo Zhang Qing Chang Jin Zeng Feng Xin Jianjun Wang Qingyan Zhu Jing Wu Jingqiao Lu Weiwei Guo Xukun Yan Hui Jiang Binfei Zhou Qi Li Xue Gao Huijun Yuan Shiming Yang Dongyi Han Zixu Mao Ping Chen Xi Lin Pu Dai 2014Cell Research2014,24,11:13
3Sediment dynamic responses of coastal salt marsh to typhoon “KAEMI” in Quanzhou Bay,Fujian Province,China显示文摘In order to understand the mechanisms of coastal protection by salt marshes during typhoon events,in situ measurements of water level,tidal current speed and direction,and suspended sediment concen-tration (SSC) were carried out using Electromagnetic Current Meter (EMCM,AEM HR),miniature pres-sure sensor (MkV/D) and Seapoint Turbidity Meter (STM) sensor on a tidal flat in Quanzhou Bay,during the period when the typhoon 'KAEMI' was passing through the region. The analysis of the data ob-tained shows that the near-bed current speed within the Spartina alterniflora marsh was generally be-low 5 cm s-1,which was apparently smaller than on the adjacent bare flat (i.e. 5―30 cm s-1). The change in the near-bed current speed in response to the typhoon event was not significant within the S. al-terniflora marsh,but the current direction was influenced by the typhoon. The effect of the typhoon on the SSC was highly significant,with the SSC reaching 13 to 19 times the values on the bare flat or within the marsh under fair weather conditions; the near-bed SSC within the marsh was higher than on the bare flat,after the typhoon landed. The near-bed suspended sediment fluxes within the marsh and on the bare flat during the typhoon event were both enhanced,i.e.,4 times larger than under fair weather conditions. During the ebb,the bottom shear stress on the bare flat exceeded the critical shear stress for sediment motion for most of the ebb duration of the tide and,therefore,the bed sediment was eroding,with the erosion flux after the typhoon landed being around 2 to 3 times the value associated with fair weather conditions. In contrast,within the S. alterniflora marsh,the bottom shear stress was mostly lower than the critical shear stress for sediment motion,or lower than the critical shear stress for the maintenance of suspension; hence,the marsh surface was dominated by settling processes,with a settling flux during the typhoon being 3 to 6 times compared with the fair weather situations. The settling flux during the ebb was up to twice the magnitude for the flood. The comparison of sediment dynamic processes between the S. alterniflora marsh and the bare flat demonstrates that during the typhoon event the bare flat was dominated by erosion,whilst the presence of S. alterniflora favored the accretion of suspended sediment.WANG AiJun GAO Shu CHEN Jian LI DongYi 2009Chinese Science Bulletin2009,54,1:12
4Identification of a novel mutation in POU3F4 for prenatal diagnosis in a Chinese family with X-linked nonsyndromic hearing loss显示文摘We present the clinical and genetic findings for a Chinese family with X-linked non-syndromic hearing loss in which the affected males showed congenital profound sensorineural hearing impairment. In two affected brothers, the computer tomography of temporal bone showed bilateral dilation of the internal auditory canal with fistulous communication between the lateral canal and the basal cochlear turn, which is consistent with the typical DFNX2 phenotype. A missense mutation (c.647G→A) in the POU3F4 gene caused a substitu- tion from glycine to glutamic acid at position 216 (p.G216E), and this mutation was found to consistently cosegregate with the deafness phenotype in the family. The mutation resulted in the loss of function of the POU3F4 by decreasing the affinity between the protein and DNA, as shown in silico by the structural analysis. Prenatal diagnosis of pregnant proband of this family revealed the c.647G→A muta- tion in DNA extracted from the amniotic fluid surrounding the fetus. The appropriate use of genetic testing and prenatal diagnosis plays a key role in reducing the recurrence of genetic defects in high-risk families.Jianzhong Li Jing Cheng Yanping Lu Yu Lu Airing Chen YiSun Dongyang Kang Xin Zhang Pu Dai Dongyi Han Huijun Yuan 2010Journal of Genetics and Genomics2010,37,12:9
5Dynamically controlling terahertz wavefronts with cascaded metasurfaces显示文摘Dynamically controlling terahertz(THz)wavefronts in a designable fashion is highly desired in practice.However,available methods working at microwave frequencies do not work well in the THz regime due to lacking suitable tunable elements with submicrometer sizes.Here,instead of locally controlling individual meta-atoms in a THz metasurface,we show that rotating different layers(each exhibiting a particular phase profile)in a cascaded metadevice at different speeds can dynamically change the effective Jonesmatrix property of the whole device,thus enabling extraordinary manipulations on the wavefront and polarization characteristics of a THz beam impinging on the device.After illustrating our strategy based on model calculations,we experimentally demonstrate two proof-of-concept metadevices,each consisting of two carefully designed all-silicon transmissive metasurfaces exhibiting different phase profiles.Rotating two metasurfaces inside the fabricated devices at different speeds,we experimentally demonstrate that the first metadevice can efficiently redirect a normally incident THz beam to scan over a wide solid-angle range,while the second one can dynamically manipulate both the wavefront and polarization of a THz beam.Our results pave the way to achieving dynamic control of THz beams,which is useful in many applications,such as THz radar,and bio-and chemical sensing and imaging.Xiaodong Cai Rong Tang Haoyang Zhou Qiushi Li Shaojie Ma Dongyi Wang Tong Liu Xiaohui Ling Wei Tan Qiong He Shiyi Xiao Lei Zhou 2021Advanced Photonics2021,3,3:8
6Mitochondrial DNA A1555G mutation screening using a testing kit method and its significance in preventing aminoglycoside-related hearing loss显示文摘To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory hearing loss patients were tested for 1555A→G mutation using a new compact testing kit, which allows clear distinction between wild type and 1555 A→G mutated mtDNAs. Results Nineteen subjects among the 546 patients (3.48%) were found to carry mtDNA A1555G mutation. The results were confirmed by sequencing in an ABI 3100 Avant sequencer. Conclusions Maternal inherited deafness families are a frequently seen in outpatient group. The detection of mtDNA 1555 A→G mutation with a low cost, ready to use detection kit is needed and suitable in China for large scale screening and preventive testing before usage of aminoglycoside antibiotics.LIU Xin,1 DAI Pu,1* HUANG Deliang,1 YUAN Huijun,1 LI Weiming,1 YU Fei,1 ZHANG Xin,1 KANG Dongyang,1 CAO Juyang,1 YANG Weiyan,1 HAN Dongyi,1 JIN Zhengce2, GUAN Minxin3 1. Department of Otolaryngology, Chinese PLA General Hospital, Beijing, China2. Weihai Aomaier Gene Technological CO.,LTD.,Weihai,Shandong 264200, China.3. Division and Program in Human Genetics and Center for Hearing and Deafness Research, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA 2006Journal of Otology2006,1,1:7
7Far-field super-resolution imaging by nonlinearly excited evanescent waves显示文摘Abbe’s resolution limit,one of the best-known physical limitations,poses a great challenge for any wave system in imaging,wave transport,and dynamics.Originally formulated in linear optics,the Abbe limit can be broken using nonlinear optical interactions.We extend the Abbe theory into a nonlinear regime and experimentally demonstrate a far-field,label-free,and scan-free super-resolution imaging technique based on nonlinear four-wave mixing to retrieve near-field scattered evanescent waves,achieving a sub-wavelength resolution ofλ∕5.6.This method paves the way for numerous new applications in biomedical imaging,semiconductor metrology,and photolithography.Zhihao Zhou Wei Liu Jiajing He Lei Chen Xin Luo Dongyi Shen Jianjun Cao Yaping Dan Xianfeng Chen Wenjie Wan 2021Advanced Photonics2021,3,2:6
8Retinal nerve fiber layer (RNFL) integrity and its relations to retinal microvasculature and microcirculation in myopic eyes显示文摘Background:The aim was to determine retinal nerve fiber layer function and its relations to retinal microvasculature and microcirculation in patients with myopia.Method:Polarization-sensitive optical coherence tomography(PS-OCT)was used to measure phase retardation per unit depth(PR/UD,proportional to the birefringence)of the retinal nerve fiber layer(RNFL).Optical coherence tomography angiography(OCTA)was used to measure macular vessel density analyzed using fractal analysis.In addition,a retinal function imager(RFI)was used to measure macular blood flow velocities in arterioles and venules.Twenty-two patients with moderate myopia(MM,refraction>3 and<6 diopters),seventeen patients with high myopia(HM,≥6 D)and 29 healthy control subjects(HC,≤3.00 D)were recruited.One eye of each patient was imaged.Results:Although the average PR/UD of the RNFL in the HM group did not reach a significant level,the birefringence of the inferior quadrant was significantly lower(P<0.05)in the HM group compared to the HC group.Significant thinning of the average RNFL and focal thinning of RFNL in temporal,superior and inferior quadrants in the HM group were found,compared to the HC group(P<0.05).There were no significant differences of retinal blood flow velocities in arterioles and venules among groups(P>0.05).The macular vessel density in both superficial and deep vascular plexuses was significantly lower in the HM group than in the other two groups(P<0.05)as well as in the MM group than in the HC group(P<0.05).The average PR/UD and PR/UD in the inferior quadrant were not related to refraction,axial length,blood flow velocities and macular vessel densities(r ranged from−0.09 to 0.19,P>0.05).Conclusions:The impairment of the retinal nerve fiber birefringence in the HM group may be one of the independent features in high myopic eyes,which appeared not to relate to macular microvascular density and blood flow velocity.Dongyi Qu Ying Lin Hong Jiang Yi Shao Yingying Shi Shriya Airen Giovanni Gregori Jianhua Wang 2018Eye and Vision2018,5,1:5
9Development of a script of phonemically balanced monosyllable lists of Mandarin-Chinese显示文摘Objectives To develop a set of monosyllable audiometry test material that can be used in speech recognition testing in Mandarin Chinese. Materials and Methods In an effort to improve reliability and efficiency in clinical practice, a set of 30 test lists of 25 monosyllable test items each was designed with consideration of the following: length of the list, phonemical balance (PB), word utility frequency, coverage of common words, and equivalency among lists. The 30 lists contained 750 monosyllabic words and were constructed on the basis of Chinese phoneme distribution probability summarized in the Manual of Acoustic. The occurrence incidence of the 22 consonants, 36 vowels, and 4 tones of the Chinese Mandarin characters in the 30 test lists were calculated. To achieve PB, 489 monosyllables were selected from the 2500 most commonly used Chinese characters and the 4000 most commonly used Chinese phrases to compile the 30 monosyllable test lists using a computer algorithm with manual adjustment. Results Thirty phonemical balanced word lists of common Mandarin Chinese monosyllabic words were compiled. Each list consisted of 25 monosyllables. A total of 489 phonemes (consonants, vowels and tones) were included in the set. Conclusions This set of lists can potentially be used as the basic lists for future development of Mandarin PB monosyllable speech test materials.JI Fei, CHEN Aiting, ZHAO Yang, XI Xin, HAN Dongyi Departments of Otorhinolaryngology-Head and Neck Surgery, Institute of Otorhinolaryngology, General Hospital of People’s Liberation Army, Beijing 100853, China 2010Journal of Otology2010,5,1:4
10Hearing Preservation in Acoustic Neuroma Surgery显示文摘Objective To report the authors’ experiences in hearing preservation during acoustic neuroma (AN) resection procedures. Methods Two cases of AN removal via retrosigmoid approach were reviewed. Hearing preservation was attempted in the aid of endoscopic technique along with continuous monitoring of the compound action potential (CAP) and auditory brainstem response(ABR) during the surgery. Results The tumor in Case 1 was 1.5 cm in diameter. The average pure-tone hearing threshold was 30 dB HL and ABR was normal. Waves I, III and V of ABR were present following tumor removal. At 7th month follow-up, audiometric thresholds and ABR inter-peak intervals had recovered to pre-operative levels, with normal facial nerve function. The patient in Case 2 had bilateral AN. The tumors measured 4.0 cm(left) and 5.0 cm (right) on MRI scans. The AN on the right side was removed first, followed by removal of the left AN four months later. Intraoperative CAP monitoring was employed during removal of the left AN. While efforts to preserve the cochlear nerve were not successful, CAPs were still present after tumor removal. Conclusions Intraoperatively recorded CAPs are not reliable in predicting postoperative hearing outcomes. In contrast, ABRs are an indicator of function of the peripheral auditory pathway. Presence of waves I, III and V following tumor removal may represent preservation of useful hearing.HAN Dongyi, YU Limei, YANG Shiming, YU LimingDepartment of Otolaryngology-Head and Neck Surgery, PLA General Hospital, Beijing 100853 2006Journal of Otology2006,1,1:4
11Efficient generation of complex vectorial optical fields with metasurfaces显示文摘Vectorial optical fields(VOFs)exhibiting arbitrarily designed wavefronts and polarization distributions are highly desired in photonics.However,current methods to generate them either require complicated setups or exhibit limited functionalities,which is unfavorable for integration-optics applications.Here,we propose a generic approach to efficiently generate arbitrary VOFs based on metasurfaces exhibiting full-motrix yet inhomogeneous Jones-matrix distributions.We illustrate our strategy with analytical calculations on a model system and an experimental demonstration of a meta-device that can simultaneously deflect light and manipulate its polarization.Based on these benchmark results,we next experimentally demonstrate the generation of a far-field VOF exhibiting both a vortex wavefront and an inhomogeneous polarization distribution.Finally,we design/fabricate a meta-device and experimentally demonstrate that it can generate a complex near-field VOF-a cylindrically polarized surface plasmon wave possessing orbital angular momentum-with an efficiency of-34%.Our results establish an efficient and ultracompact platform for generating arbitrary predesigned VOFs in both the near-and far-fields,which may find many applications in optical manipulation and communications.Dongyi Wang Feifei Liu Tong Liu Shulin Sun Qiong He Lei Zhou 2021Light(Science & Applications)2021,10,4:3
12Nanofiber/nanowires-based flexible and stretchable sensors显示文摘Nanofibers/nanowires with one-dimension(1D)nanostructure or well-patterned microstructure have shown distinctly advantages in flexible and stretchable sensor fields,owing to their remarkable tolerance against mechanical bending or stretching,outstanding electronic/optoelectronic properties,good transparency,and excellent geometry.Herein,latest summaries in the unique structure and properties of nanofiber/nanowire function materials and their applications for flexible and stretchable sensor are highlighted.Several types of high-performance nanofiber/nanowire-based flexible pressure and stretchable sensors are also reviewed.Finally,a conclusion and prospect for 1D nanofiber/nanowires-based flexible and stretchable sensors are also intensively discussed.This summary offers new insights for the development of flexible and stretchable sensor based 1D nanostructure in next-generation flexible electronics.Dongyi Wang Lili Wang Guozhen Shen 2020Journal of Semiconductors2020,41,4:2
13非相应的结束加入: 进展和边疆显示文摘DNA 双海滨裂缝(DSB ) 是 DNA 损坏的最严肃的形式。在人的房间,加入的非相应的结束(NHEJ ) 是为 DSB 的修理的主要小径。在在 NHEJ 的 NHEJ 修理 strategies.These 变化的不同子集的 DSB 结果的不同类型修理策略取决于众多的元素,例如 NHEJ 相关的蛋白质, DSB 结束的复杂性,和多蛋白质建筑群的空间顺序、时间顺序的形成的灵活招募。在一方面, DNA DSB 修理的当前的研究集中于在相应再结合之间的修理小径选择 ? 并且经典著作或 alternativeNHEJ。在另一方面,增加研究也加深了意义并且挖了进在 theNHEJ 小径和染色体组织和老化的区域之间的交叉结合。尽管显著进步在过去的十年期间在阐明被成为了 theunderlying 原则,响应 remainslargely 未知的 DSB 和需要的不同类型的行动的详细机制在未来学习的进一步的评估。Kai Yang Rong Guo Dongyi Xu 2016Acta Biochimica et Biophysica Sinica2016,48,7:2
14Extremely low penetrance of deafness associated with the mitochondrial 12S rRNA mutation in 16 Chinese families: Implication for early detection and prevention of deafness显示文摘Pu Dai Xin Liu Dongyi Han Yaping Qian Deliang Huang Huijun Yuan Weiming Li Fei Yu Ruining Zhang Hongyan Lin Yong He Youjun Yu Quanzhu Sun Huaiyi Qin Ronghua Li Xin Zhang Dongyang Kang Juyang Cao Wie-Yen Young Min-Xin Guan 2005Biochemical and Biophysical Research Communications2005,,1:2
15Super broadband absorbing hierarchical CoFe alloy/porous carbon@carbon nanotubes nanocomposites derived from metal-organic frameworks显示文摘The exploitation of electromagnetic wave absorption(EMA) materials has attracted ever-increasing attention,not only because electromagnetic wave(EMW) originated from overuse of electronic products has threatened human' health seriously,but also because EMA materials can effectively protect radar stealth from being detected.However,it is still a challenge to obtain broadband and efficient EMA materials to satisfy practical applications.In this work,we developed a series of hierarchical CoFe alloy/porous carbon@carbon nanotubes(CoFe/PC@CNTs) nanocomposites through revising the proportion of Fe^(2+) in the metal-organic frameworks(MOFs)(CoFe-ZIF) precursor and one-step simple pyrolysis process.The cross deposition between CoFe alloy,carbon nanotubes(CNTs),and porous carbon(PC) formed a double conductive network,favoring for achieving excellent EMA property.Surprisingly,when the filler mass ratio is only 10 wt%,the optimized CoFe/PC@CNTs nanocomposites display the best EMA capability,whose minimum reflection loss(RL_(min)) value is-68.94 dB at 13.69 GHz and the effective absorption band(EAB,<-10 dB) reaches up 9.14 GHz with a matching thickness of 2.63 mm.In addition,the largest EAB can achieve up to 11 GHz(3.35-14.35 GHz) during all matching thicknesses.The splendid EMA performance benefits the favorable dielectric loss provided by the double conductive network,the good magnetic loss benefited from the evenly distributed CoFe alloy,the excellent impedance matching,rich transmission paths,and multiple polarization.Therefore,such EMA materials with super broadband absorbing provide desirable candidates for lightweight and high-efficient microwave absorbers.Siyao Guo Yunfeng Bao Ying Li Hailong Guan Dongyi Lei Tiejun Zhao Baomin Zhong Zhihong Li 2022Journal of Materials Science & Technology2022,,23:2
16A critical review of mineral–microbe interaction and co-evolution:mechanisms and applications显示文摘Mineral–microbe interactions play important roles in environmental change,biogeochemical cycling of elements and formation of ore deposits.Minerals provide both beneficial(physical and chemical protection,nutrients,and energy)and detrimental(toxic substances and oxidative pressure)effects to microbes,resulting in mineral-specific microbial colonization.Microbes impact dissolution,transformation and precipitation of minerals through their activity,resulting in either genetically controlled or metabolism-induced biomineralization.Through these interactions,minerals and microbes co-evolve through Earth history.Mineral–microbe interactions typically occur at microscopic scale but the effect is often manifested at global scale.Despite advances achieved through decades of research,major questions remain.Four areas are identified for future research:integrating mineral and microbial ecology,establishing mineral biosignatures,linking laboratory mechanistic investigation to field observation,and manipulating mineral–microbe interactions for the benefit of humankind.Hailiang Dong Liuqin Huang Linduo Zhao Qiang Zeng Xiaolei Liu Yizhi Sheng Liang Shi Geng Wu Hongchen Jiang Fangru Li Li Zhang Dongyi Guo Gaoyuan Li Weiguo Hou Hongyu Chen 2022National Science Review2022,9,10:2
17Global well-posedness of the MHD equations via the comparison principle显示文摘In this paper,we prove the global well-posedness of the incompressible magneto-hydrodynamics(MHD)equations near a homogeneous equilibrium in the domain R^k×T^(d-k),d≥2,k≥1 by using the comparison principle and constructing the comparison function.Dongyi Wei Zhifei Zhang 2018Science China Mathematics2018,61,11:2
18Regulation of fruit ripening by the brassinosteroid biosynthetic gene SlCYP90B3 via an ethylenedependent pathway in tomato显示文摘The essential role of ethylene in fruit ripening has been thoroughly studied.However,the involvement of brassinosteroids(BRs)in the regulation of fruit ripening and their relationship with the ethylene pathway are poorly understood.In the current study,we found that BRs were actively synthesized during tomato fruit ripening.We then generated transgenic lines overexpressing or silencing SlCYP90B3,which encodes a cytochrome P450 monooxygenase that catalyzes the rate-limiting step of BR synthesis.The expression level of SlCYP90B3 was positively related to the contents of bioactive BRs as well as the ripening process in tomato fruit,including enhanced softening and increased soluble sugar and flavor volatile contents.Both carotenoid accumulation and ethylene production were strongly correlated with the expression level of SlCYP90B3,corroborated by the altered expression of carotenoid biosynthetic genes as well as ethylene pathway genes in transgenic tomato fruits.However,the application of the ethylene perception inhibitor 1-methycyclopropene(1-MCP)abolished the promotion effect of SlCYP90B3 overexpression on carotenoid accumulation.Taken together,these results increase our understanding of the involvement of SlCYP90B3 in bioactive BR biosynthesis as well as fruit ripening in tomato,thus making SlCYP90B3 a target gene for improvement of visual,nutritional and flavor qualities of tomato fruits with no yield penalty.Songshen Hu Lihong Liu Shuo Li Zhiyong Shao Fanliang Meng Haoran Liu Wenyi Duan Dongyi Liang Changqing Zhu Tao Xu Qiaomei Wang 2020Horticulture Research2020,7,1:2
19Burden of concomitant asthma and COPD in a medicaid population显示文摘Shaya FT Dongyi D Akazawa MO 2008Chest2008,134,1:1
20Burden of concomitant asthma and COPD in a Medicaid population显示文摘Syaya FT Dongyi D Akazawa MO 2008Chest2008,,134:1
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