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| 1 | Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis:a prospective multicenter randomized controlled trial显示文摘Objective:Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding.The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation(RCA)combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis(IHD)treatment.Methods:Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments,and were randomly divided into RCA group and saline flushing group.In the RCA group,0.04 g/mL sodium citrate was infused from the start of the dialysis line during blood draining and at the venous expansion chamber.The sodium citrate was stopped after 3 h of dialysis,which was changed to sequential dialysis without anticoagulant.The hazard ratios for coagulation were according to baseline.Results:A total of 159 patients and 208 sessions were enrolled,including RCA group(80 patients,110 sessions)and saline flushing group(79 patients,98 sessions).The incidence of severe coagulation events of extracorporeal circulation in the RCA group was significantly lower than that in the saline flushing group(3.64%vs.20.41%,P<0.001).The survival time of the filter pipeline in the RCA group was significantly longer than that in the saline flushing group((238.34±9.33)min vs.(221.73±34.10)min,P<0.001).The urea clearance index(Kt/V)in the RCA group was similar to that in the saline flushing group with no statistically significant difference(1.12±0.34 vs.1.08±0.34,P=0.41).Conclusions:Compared with saline flushing,the two-stage RCA combined with a sequential anticoagulation strategy significantly reduced extracorporeal circulation clotting events and prolonged the dialysis time without serious adverse events. | Xiaoyan TANG Dezheng CHEN Ling ZHANG Ping FU Yanxia CHEN Zhou XIAO Xiangcheng XIAO Weisheng PENG Li CHENG Yanmin ZHANG Hongbo LI Kehui LI Bizhen GOU Xin WU Qian YU Lijun JIAN Zaizhi ZHU Yu WEN Cheng LIU Hen XUE Hongyu ZHANG Xin HE Bin YAN Liping ZHONG Bin HUANG Mingying MAO | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，11： | 4 |
| 2 | U-Pb Zircon and Re-Os Molybdenite Geochronology of the W-Mo Mineralized Region of South Qinling, China, and their Tectonic Implications显示文摘A W-Mo mineralized region is located along the northern margin of the South Qinling tectonic belt of China. WMo mineralization occurs mainly in Cambrian–Ordovician clastic and carbonate rocks, and the ore bodies are structurally controlled by NW–SE-and NNE–SSW-striking faults. Evidence for magmatism in the area is widespread and is dominated by intermediate–felsic intrusives or apophyses, such as the Dongjiangkou, Yanzhiba, Lanbandeng, and Sihaiping granitic bodies. Quartz-vein-type mineralization and fault-controlled skarn-type mineralization dominate the ore systems, with additional enrichment in residual deposits. At present, there are few or insufficient studies on(1) the age of mineralization,(2) the relationship between intermediate–felsic granite and W-Mo mineralization,(3) the source of ore-forming materials, and(4) the metallogenic and tectonic setting of the mineralized area. In this paper, we present geochronology results for numerous intrusive granitic bodies in the South Qinling tectonic belt. U-Pb zircon geochronology of the Lanbandeng monzogranite and Wangjiaping biotite monzogranite yields ages of 222.7 ± 2.3 and 201.9 ± 1.8 Ma, respectively. In contrast to the Late Triassic age of the Lanbandeng monzogranite, the age of the newly discovered Wangjiaping biotite monzogranite places it at the Triassic–Jurassic boundary. Re-Os molybdenite geochronology on the Qipangou W-Mo deposit yielded a model age of 199.7 ± 3.9 Ma, indicating the deposit formed in the early Yanshanian period of the Early Jurassic. Granitoid intrusions in the mineralized area are characterized by composite granite bodies that crystallized at ca. 240–190 Ma. While there were multiple stages of intrusion, most occurred at 210–220 Ma, with waning magmatic activity at 200–190 Ma. The Re-Os age of molybdenite in the region is ca. 200–190 Ma, which may represent a newly discovered period of W-Mo metallogenesis that occurred during the final stages of magmatism. The heat associated with this magmatism drove ore formation and might have provided additional ore-forming components for metallogenesis(represented by the Wangjiaping biotite monzogranite). Ore materials in the mineralized area were derived from mixed crustal and mantle sources. Enrichment of the region occurred during intracontinental orogenesis in the late Indosinian–Yanshanian, subsequent to the main Indosinian collision. At this time, the tectonic environment was dominated by extension and strike-slip motion. | HAN Ke YANG Xingke CHAO Huixia HE Hujun RUAN Shiqi GAO Yunfeng ZHANG Weisheng ZHU Wei JIN Gang | 2021 | Acta Geologica Sinica(English Edition)2021，95，2： | 3 |
| 3 | Expression of Both Matrix Metalloproteinase-2 and Its Tissue Inhibitor-2 in Tunica Media of Radial Artery in Uremic Patients显示文摘 | Aiqin Shan Canxin Zhou Yongping He Weisheng Feng Gun Chen Guoping Zhong | 2013 | Renal Failure2013，，1： | 1 |
| 4 | p120 Catenin Translocation is Involved in Enhancement of Hepatoma Cellular Malignant Features显示文摘 | Huayi Huang Chaozan Nong Weisheng He Lingxiao Guo Shaoyun Nong Lili Pan Xiliang Zha | 2005 | Chinese Journal of Clinical Oncology2005，2，4： | 1 |
| 5 | Hybrid Kansei Engineering System Applied to Product Design显示文摘 | Chen Kuoxiang He Mingquan Guan Weisheng | 2004 | Industrial Design2004，32，2： | 1 |
| 6 | Theorelical and experimental analysis of interchannel erosstalk between TWDM and fronthaul wavelengths due to stimulated Raman scattering显示文摘 | Li Jun He Hao Hu Weisheng | 2015 | Optics Express2015，23，7： | 1 |
| 7 | Synthesis of Tribolure,the Common Aggregation Pheromone of Four Tribolium Flour Beetles显示文摘Herein we report a synthesis of the natural tribolure,an aggregation pheromone which consists of(4R,8S)-,(4R,8R)-,(4S,8S)-,and(4S,8R)-4,8-dimethyldecanals in a ratio of 4/4/1/1,from(R)-4-methyl-δ-valerolactone,a by-product of the degradation of steroidal sapogenins.Merging the stereoisomers of the same ratios into one synthetic target and using the same chiron for the construction of the C4 stereocenters are notable features of this synthesis. | Chao Wang Chengyu He Yong Shi Hua Xiang Weisheng Tian | 2015 | Chinese Journal of Chemistry2015，33，6： | 0 |
| 8 | Coordination Control Method for Preventing Sub/Super Synchronous Oscillations of Multi-wind Farm Systems显示文摘In recent years,sub/super-synchronous oscillations occur frequently in large-scale wind power bases throughout China.Since the oscillation frequencies are close to the fundamental frequency,the current components can spread over a large area,and may destroy the shafting of rotating devices in the power grid.Improving the control strategy and parameters of wind turbines can prevent this problem to some extent,however,due to complex operational conditions and continuous development of wind power,the off-line improvement measures on wind turbines cannot eliminate the potential oscillation risks.This paper proposes an oscillation risk screening and stability assessment method,and develops a coordination control method for large-scale wind farm systems to prevent sub/supersynchronous oscillations.The Nyquist criterion and the modal analysis method are combined to generate quantitative factors for the stability assessment and the control strategy design.The coordination control method consists of minute-level power coordinated allocation and second-level fast power control to prevent and eliminate the oscillations.A detailed simulation model of a multiple wind farms system originated from an actual wind power base in China is presented to verify the effectiveness of the proposed method. | Guoqing He Weisheng Wang Haijiao Wang | 2023 | CSEE Journal of Power and Energy Systems2023，9，5： | 0 |
| 9 | A Royal Jelly Mixture with Berberine for Dressing Change on a Refractory Skin Ulcer:A Case Report显示文摘It has been reported that a 92-year-old female had got a bruise superficial wound on her right leg one and a half years ago,developing into refractory skin ulcer due to improper management before.A prepared cream,mixed royal jelly with berberine for dressing change,was made on the scene through the crush of berberine tablets,working with fresh royal jelly.Topical dressing change with the cream was done every 3 days,and two months later,such the ulcer became clean and was covered fully with fresh granulation tissue.This kind of cream consists of the ingredients of TCM purely,free of antibiotic,and being quite effective clinically,also helpful for proper use of antibiotic. | Weisheng He Mimi Zhou Yue Chen | 2021 | Journal of Geriatric Medicine2021，3，2： | 0 |
| 10 | An Introduction of the Vaporized Therapy with Tea Herb Drink for Relieving Agitation due to Pulmonary Encephalopathy显示文摘What methods would you choose apart from increasing sedatives for agitation in an advanced patient with hypercapnic encephalopathy due to AECOPD?This is a 94-year-old female who suffered from COPD for over 30 years,occurred with an accelerated episode of cough,productive sputum and a dropping down to 86%in SatO₂due to a cold weather.A diagnosis of pulmonary encephalopathy(PE)was made on the basis of the subsequent agitation and delirium,and the sedatives,such as quatiepine and haloperidol,had to be given for her mental excitation respectively,but she still pulled out indwelling needle herself and refused to any infusion therapy.As an alternative,a vaporized therapy integrated with tea herb drinking had to be applied to relieving her agitation,being designed as the vaporization of the inhaled oxygenation by means of high-flow oxygenation device(HFOD),with an ampoule of ambroxol mixed into the inhaler and simultaneous drinking of TCM tea herb for reducing sputum,helping dissolve the mucoid bolts inside her terminal bronchioles when being infected.We thought that a better efficacy would be achieved for hypercapnic encephalopathy due to AECOPD if we concentrate on a good ventilation of small airway through the vaporized therapy. | Jianbo Hong Mimi Zhou Weisheng He Yue Chen | 2021 | Journal of Geriatric Medicine2021，3，2： | 0 |
| 11 | Fast Bulky Anion Conduction Enabled by Free Shuttling Phosphonium Cations显示文摘Highly conductive anion-exchange membranes(AEMs)are desirable for applications in various energy storage and conversion technologies.However,conventional AEMs with bulky HCO3-or Br-as counterion generally exhibit low conductivity because the covalent bonding restrains the tethered cationic group’s mobility and rotation.Here,we report an alternative polyrotaxane AEM with nontethered and free-shuttling phosphonium cation.As proved by temperature-dependent NMR,solid-state NMR,and molecular dynamics simulation,the phosphonium cation possesses a thermally trigged shuttling behavior,broader extension range,and greater mobility,thus accelerating the diffusion conduction of bulky anions.Owing to this striking feature,high HCO_(3)-conductivity of 105 mS cm^(-1) at 90℃ was obtained at a relatively lower ion-exchange capacity of 1.17 mmol g^(-1).This study provides a new concept for developing highly conductive anion-exchange membranes and will catalyze the exploration of new applications for polyrotaxanes in ion conduction processes. | Xiaolin Ge Yubin He Kaiyu Zhang Xian Liang Chengpeng Wei Muhammad A.Shehzad Wanjie Song Zijuan Ge Geng Li Weisheng Yu Liang Wu Tongwen Xu | 2022 | Research2022，，1： | 0 |
| 12 | Demonstration of a manufacturable SOT-MRAM multiplexer array towards industrial applications显示文摘We have successfully demonstrated a 1 Kb spin-orbit torque(SOT)magnetic random-access memory(MRAM)multiplexer(MUX)array with remarkable performance.The 1 Kb MUX array exhibits an in-die function yield of over 99.6%.Additionally,it provides a sufficient readout window,with a TMR/RP_sigma%value of 21.4.Moreover,the SOT magnetic tunnel junctions(MTJs)in the array show write error rates as low as 10^(-6)without any ballooning effects or back-hopping behaviors,ensuring the write stability and reliability.This array achieves write operations in 20 ns and 1.2 V for an industrial-level temperature range from-40 to 125℃.Overall,the demonstrated array shows competitive specifications compared to the state-of-the-art works.Our work paves the way for the industrial-scale production of SOT-MRAM,moving this technology beyond R&D and towards widespread adoption. | Chuanpeng Jiang Jinhao Li Hongchao Zhang Shiyang Lu Pengbin Li Chao Wang Zhongkui Zhang Zhengyi Hou Xu Liu Jiagao Feng He Zhang Hui Jin Gefei Wang Hongxi Liu Kaihua Cao Zhaohao Wang Weisheng Zhao | 2023 | Journal of Semiconductors2023，44，12： | 0 |
| 13 | Multi-Hop Transmission Method of 5G Millimeter Wave Relay Based on Network Coding显示文摘With the rapid development of the Internet technology,millimeter wave(mmWave)will be used as a supplement to 5G low frequency bands to meet the extremely high system capacity requirements of 5G in hot spots.Although 5G mmWave communication can adapt to the needs of 5G network and carry a large amount of transmitted data,transmission stability has become one of the key technical issues of 5G network mmWave communication due to problems such as strong attenuation and poor penetration of mmWave.In order to improve the efficiency of the mmWave multi-hop transmission,we propose a 5G mmWave multi-hop transmission method based on network coding,which can adapt to the current wireless network environment,improve spectrum efficiency and increase network throughput.Based on MATLAB simulation experiments,it is verified that the proposed method can greatly improve the transmission efficiency and reduce the signal loss under the premise of ensuring the accurate signal transmission. | Yilin Wang Weisheng He Xuwei Fan Lianfen Huang Jie Yang Yuliang Tang | 2022 | China Communications2022，19，12： | 0 |
| 14 | A fewest-turn-and-shortest path algorithm based on breadth-first search显示文摘Many cognitive studies have indicated that the path simplicity may be as important as its distance travelled.However,the optimality of paths for current navigation system is often judged purely on the distance travelled or time cost,and not the path simplicity.To balance these factors,this paper presented an algorithm to compute a path that not only possesses fewest turns but also is as short as possible by utilizing the breadth-first-search strategy.The proposed algorithm started searching from a starting point,and expanded layer by layer through searching zero-level reachable points until the endpoint is found,and then deleted unnecessary points in the reverse direction.The forward searching and backward cleaning strategies were presented to build a hierarchical graph of zero-level reachable points,and form a fewestturn-path graph(G^(*)).After that,a classic Dijkstra shortest path algorithm was executed on the G^(*) to obtain a fewestturn-and-shortest path.Comparing with the shortest path in Baidu map,the algorithm in this work has less than half of the turns but the nearly same length.The proposed fewest-turn-and-shortest path algorithm is proved to be more suitable for human beings according to human cognition research. | Yan ZHOU Weisheng WANG Di HE Zhe WANG | 2014 | Geo-Spatial Information Science2014，17，4： | 0 |
| 15 | Fast Bulky Anion Conduction Enabled by Free Shuttling Phosphonium Cations显示文摘Highly conductive anion-exchange membranes(AEMs)are desirable for applications in various energy storage and conversion technologies.However,conventional AEMs with bulky HCO_(3)^(-)or Br-as counterion generally exhibit low conductivity because the covalent bonding restrains the tethered cationic group’s mobility and rotation.Here,we report an alternative polyrotaxane AEM with nontethered and free-shuttling phosphonium cation.As proved by temperature-dependent NMR,solid-state NMR,and molecular dynamics simulation,the phosphonium cation possesses a thermally trigged shuttling behavior,broader extension range,and greater mobility,thus accelerating the diffusion conduction of bulky anions.Owing to this striking feature,high HCO_(3)^(-)conductivity of 105 mS cm^(-1)at 90℃ was obtained at a relatively lower ion-exchange capacity of 1.17 mmol g^(-1).This study provides a new concept for developing highly conductive anion-exchange membranes and will catalyze the exploration of new applications for polyrotaxanes in ion conduction processes. | Xiaolin Ge Yubin He Kaiyu Zhang Xian Liang Chengpeng Wei Muhammad A.Shehzad Wanjie Song Zijuan Ge Geng Li Weisheng Yu Liang Wu Tongwen Xu | 2021 | Research2021，，1： | 0 |
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