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| 1 | Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors显示文摘 | Zhu, Jie Ming, Chang Fu, Xin Duan, Yaou Duc Anh Hoang Rutgard, Jeffrey Zhang, Runze Wang, Wenqiu Hou, Rui Zhang, Daniel Zhang, Edward Zhang, Charlotte Hao, Xiaoke Xiong, Wenjun Zhang, Kang | 2017 | Cell Research2017，27，6： | 11 |
| 2 | Ti/SnO2-Sb2O5-RuO2/α-PbO2/β-PbO2 electrodes for pollutants degradation显示文摘 | Yinghan Zheng Wenqiu Su Shengying Chen | 2011 | Chemcal Engineering Journal2011，174，1： | 1 |
| 3 | Solu- ble Polyimides Based on a Novel Pyridine-eontaining Dia- mine m,p-PAPP and Various Aromatic Dianhydrides显示文摘 | Yan Shanyin Chen Wenqiu Yang Xiaojin | 2011 | Polym Bull2011，66，： | 1 |
| 4 | Testing toxicity of multiple intravitreal injections of bevacizumab in rabbit eyes显示文摘 | Weiqi Xu Hong Wang Fenghua Wang Yuan Jiang Xian Zhang Wenqiu Wang Jin Qian Xun Xu Xiaodong Sun | 2010 | Canadian Journal of Ophthalmology/Journal canadien d’ophtalmologie2010，，4： | 1 |
| 5 | Necrostatin-1 Protects Photoreceptors from Cell Death and Improves Functional Outcome after Experimental Retinal Detachment显示文摘 | Kai Dong Hong Zhu Zhengyu Song Yuanyuan Gong Fenghua Wang Wenqiu Wang Zhi Zheng Zhang Yu Qing Gu Xun Xu Xiaodong Sun | 2012 | The American Journal of Pathology2012，，5： | 1 |
| 6 | Ti/SnO 2 –Sb 2 O 5 –RuO 2 /α-PbO 2 /β-PbO 2 electrodes for pollutants degradation显示文摘 | Yinghan Zheng Wenqiu Su Shengying Chen Xingzheng Wu Xueming Chen | 2011 | Chemical Engineering Journal2011，，1： | 1 |
| 7 | Reflection and transmission of acoustic waves on multilayered porous media显示文摘Based on the Boit theory of acoustic wave propagation in fluid-satu-rated porous medium we have studied in this paper the acoustic reflection andtransmission on multilayered porous media,in which the adequate boundaryconditions across the interfaces are taken into account.Numerical calculationsof the reflection and transmission coefficients at different incident angles andfrequencies of the fast compressional wave incident on porous media with threeor four layers are presented.The results indicate that the maximum or mini-mum reflection and transmission coefficients appear at certain ratios of thewavelength to the thickness.The acoustic incident angle and porous mediumproperties are shown to affect significantly these coefficients.As an example,the measured transmission coefficients in a water-saturated fused glass beadsample are in good agreement with theoretical prediction. | QIAO Wenxiao(Department of Petroleum Exploration, University of Petroleum, Dongying 257062)WANGYaojun WU Wenqiu(Institute of Acoustics, Nanjing University. Nanjing 210008) | 1993 | Chinese Journal of Acoustics1993，12，1： | 1 |
| 8 | Testing toxicity of multiple intravitreal injections of bevacizumab in rabbit eyes显示文摘 | Weiqi Xu Hong Wang Fenghua Wang Yuan Jiang Xian Zhang Wenqiu Wang Jin Qian Xun Xu Xiaodong Sun | 2010 | Canadian Journal of Ophthalmology/Journal canadien d’ophtalmologie2010，，4： | 1 |
| 9 | Research and Exploration of Cultivation Model of Innovation Ability of College Students Majoring in Computer显示文摘 | Zhu Wenqiu Li Changyun Man Junfeng | 2012 | Fujian Computer2012，，1： | 1 |
| 10 | Effect of Dietary Phosphorus on the Growth and Body Components of Juvenile Synechogobius hasta显示文摘The effect of dietary phosphorus on the growth and body components of juvenile Synechogobius hasta was determined. Different percentages of dietary phosphorus (0.63, 0.77, 0.93, 1.06, 1.22 and 1.36) were tested by feeding the fish (body weight, 15.81 g ± 0.32 g; 20 individuals each group; 3 groups each percentage) at a surplus of 5%–10% above satiation for 35 d. Dietary phosphorus did not significantly affect the specific growth rate, feed intake, feed conversion ratio and protein efficiency rate. Nitrogen retention was found to be the highest in fish fed the diet containing 1.06% of phosphorus; however, this was not significantly different from other diets. Fish fed the diet containing 0.93% of phosphorus showed the highest phosphorus retention; similar phosphorus retention rates were found in fish fed the diets containing 0.77% and 1.06% of phosphorus. Fish fed the diet containing the highest percentage of dietary phosphorus were found to contain the least whole body lipid, lower than fish fed other diets (P<0.05). The protein content increased from 18.59% to 19.55% (although not significant) with the decrease of body lipid content (P>0.05). The contents of the whole body ash, whole body phosphorus and vertebrae phosphorus increased with dietary phosphorus percentage up to 1.06 (P<0.05), reaching a plateau after that. Dietary phosphorus did not significantly influence the muscle components (protein, lipid and moisture). Condition factor and hepatosomatic index were the highest in fish fed the diet containing 0.63% of dietary phosphorus; however, this was not significantly different from those of other diets. The secondorder polynomial regression of phospho- rus retention against dietary phosphorus identified a breakpoint at 0.88% of dietary phosphorus. However, the dietary requirement of phosphorus for maintaining maximum phosphorus storage determined by broken-line analysis of the contents of whole body phosphorus, and ash and vertebrae phosphorus was 1.06% of the diet. | LUO Zhi LI Xiaodong GONG Shiyuan XI Wenqiu LI Yali | 2009 | Journal of Ocean University of China2009，8，1： | 1 |
| 11 | Bayesian classification of halftone image based on region covariance显示文摘 | Wen Zhiqiang Hu Yongxiang Zhu Wenqiu | 2013 | Intelligent System Design and Engineering Applications2013，，3： | 1 |
| 12 | Single-cluster electronics using metallic clusters:Fabrications,regulations,and applications显示文摘Metallic clusters,ranging from 1 to 2 nm in size,have emerged as promising candidates for creating nanoelectronic devices at the single-cluster level.With the intermediate quantum properties between metals and semiconductors,these metallic clusters offer an alternative pathway to silicon-based electronics and organic molecules for miniaturized electronics with dimensions below 5 nm.Significant progress has been made in studies of single-cluster electronic devices.However,a clear guide for selecting,synthesizing,and fabricating functional single-cluster electronic devices is still required.This review article provides a comprehensive overview of single-cluster electronic devices,including the mechanisms of electron transport,the fabrication of devices,and the regulations of electron transport properties.Furthermore,we discuss the challenges and future directions for single-cluster electronic devices and their potential applications. | Caiyun Wei Wei Xu Shurui Ji Ruiyun Huang Junyang Liu Wenqiu Su Jie Bai Jiale Huang Wenjing Hong | 2024 | Nano Research2024，17，1： | 0 |
| 13 | Whether human-induced activities could change the gradient pattern of coastal land use along the sea-land direction:a case study in Manila Bay,Philippines显示文摘Increasing intense human activities have largely changed the coastal landscape and caused many environmental issues.However,whether human-induced activities could change the coastal land use gradient pattern,an important coastal zonal characteristic along the sea-land direction,remains unclear.Manila Bay was selected as the study area in this work.According to the distance of the land use and land cover(LULC)to the coastline,we clustered the typical coastal land use sequence patterns(CLUSPs)along the sea-land direction between 1988 and 2016 in Manila Bay and found the following.(1)Four typical CLUSPs,including the natural CLUSP dominated by forest land and grassland,the agricultural CLUSP dominated by dry farm and paddy field,the urbanised CLUSP dominated by construction land and the fishery CLUSP dominated by fishing farm,were mined in 1988.Three typical CLUSPs(a natural CLUSP,an intermediate CLUSP between the agricultural and urbanised CLUSPs,and a fishery CLUSP)were mined in 2016.(2)Affected by the dominant LULC,these typical CLUSPs showed a regular spatial pattern along the sea-land direction.For example,the typical natural CLUSP showed a landward pattern due to the long distance between the forest land and grassland and the coastline.(3)However,influenced by urban and aquaculture expansion,the land intensification of the CLUSP exhibited an obvious increase and caused the decrease of the CLUSP diversity from 1988 to 2016.The increase in the area of LULC coverage showed no obvious correlation with its distance from the coastline(DFC),but the net increase rate of LULC coverage had a significant negative correlation with the DFC.Therefore,human-induced activities have a large impact on the gradient pattern of coastal land use along the sea-land direction. | Zhi Ding Fenzhen Su Yanan Chen Ying Liu Xue Feng Wenqiu Hu Fengqin Yan He Li Pujia Yu Xuguang Tang | 2023 | Acta Oceanologica Sinica2023，42，2： | 0 |
| 14 | Micro-Expression Recognition Based on Spatio-Temporal Feature Extraction of Key Regions显示文摘Aiming at the problems of short duration,low intensity,and difficult detection of micro-expressions(MEs),the global and local features of ME video frames are extracted by combining spatial feature extraction and temporal feature extraction.Based on traditional convolution neural network(CNN)and long short-term memory(LSTM),a recognition method combining global identification attention network(GIA),block identification attention network(BIA)and bi-directional long short-term memory(Bi-LSTM)is proposed.In the BIA,the ME video frame will be cropped,and the training will be carried out by cropping into 24 identification blocks(IBs),10 IBs and uncropped IBs.To alleviate the overfitting problem in training,we first extract the basic features of the preprocessed sequence through the transfer learning layer,and then extract the global and local spatial features of the output data through the GIA layer and the BIA layer,respectively.In the BIA layer,the input data will be cropped into local feature vectors with attention weights to extract the local features of the ME frames;in the GIA layer,the global features of the ME frames will be extracted.Finally,after fusing the global and local feature vectors,the ME time-series information is extracted by Bi-LSTM.The experimental results show that using IBs can significantly improve the model’s ability to extract subtle facial features,and the model works best when 10 IBs are used. | Wenqiu Zhu Yongsheng Li Qiang Liu Zhigao Zeng | 2023 | Computers, Materials & Continua2023，77，10： | 0 |
| 15 | Severe graft-versus-host disease post allogeneic hematopoietic stem cell transplantation due to loss of HLA heterozygosity in recipient lymphocytes after full graft rejection显示文摘Germ cell tumors complicated by hematological malignancy(HM)are a rare clinical phenomenon.Allogeneic hematopoietic stem cell transplantation(allo-HSCT)is a potentially effective therapy,but graft-versus-host disease(GVHD)is a life-threatening complication.We report a case of a 13-year-old female patient diagnosed with germ cell tumors followed by acute lymphoblastic leukemia.After chemotherapy,she received allo-HSCT and her chimerism rate decreased rapidly to near zero by 6 months without evidence of HM recurrence.However,she developed severe,multiorgan GVHD-like manifestations.DNA analysis revealed the pathogenesis of GVHD to be loss of HLA heterozygosity in recipient hematopoietic cells. | Song Xue Lili Miao Zimu Gong Wenqiu Huang Yongping Zhang Fuhong Liu Jingbo Wang | 2023 | Cancer Innovation2023，2，4： | 0 |
| 16 | Author Correction:Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors显示文摘In the in itial published versi on of this article,we in advertently stated that Mall procedures were con ducted with the approval and under the supervision of the Institutional Animal Care and Use Committee(IACUC)at the University of California,San Diego'.Given that all animal work that was conducted for this project was performed at the City University of Hong Kong and Guangzhou Women and Childre n's Medical Center,we would like to in stead,acknowledge these programs for their oversight of the animal studies.This correction does not affect the description of the results or the conclusions of this work. | Jie Zhu Chang Ming Xin Fu Yaou Duan Due Anh Hoang Jeffrey Rutgard Runze Zhang Wenqiu Wang Rui Hou Daniel Zhang Edward Zhang Charlotte Zhang Eye Gene Therapy Consortium Xiaoke Hao Wenjun Xiong Kang Zhang | 2019 | Cell Research2019，29，4： | 0 |
| 17 | Genetic and environmental factors strongly influence risk,severity and progression of age-related macular degeneration显示文摘Age-related macular degeneration(AMD)is characterized by complex interactions between genetic and environmental factors.Here we genotyped the selected 25 single-nucleotide polymorphisms(SNPs)in 983 cases with advanced AMD and 271 cases with intermediate AMD and build an AMD life-risk score model for assessment of progression from intermediate to advanced AMD.We analyzed the performance of the prediction model for geographic atrophy progressors or choroidal neovascularization progressors versus non-progressors based on the 25 SNPs plus body mass index and smoking status.Our results suggest that a class prediction algorithm can be used for the risk assessment of progression from intermediate to late AMD stages.The algorithm could also be potentially applied for therapeutic response,and toward personalized care and precision medicine. | Wenqiu Wang Katarzyna Gawlik Joe Lopez Cindy Wen Jie Zhu Frances Wu William Shi Samuel Scheibler Huimin Cai Ram Vairavan Alexander Shi Weldon Haw Henry Ferreyra Ming Zhang Sherman Chang Kang Zhang | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 0 |
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