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| 1 | Effects of drought stress on photosynthesis and chlorophyll fluorescence images of soybean(Glycine max)seedlings显示文摘The main purpose of this research is to provide a theoretical foundation for the screening of drought-resistant soybean varieties and to establish an efficient method to detect the PSII actual photochemical quantum yields efficiently.Three soybean varieties were compared in this experiment after 15 d when they were planted in a greenhouse.These varieties were then exposed to light drought stress(LD)and serious drought stress(SD)conditions.With five times’measurement,chlorophyll fluorescence and soil-plant analysis development considered as the main basis for this study.Several parameters in SD conditions significantly reduced,such as net photosynthetic rates(Pn),stomatal conductance(Gs),PSII primary light energy conversion efficiency(Fv/FM),PSII actual photochemical quantum yields[Y(II)],photochemical quenching coefficient(qP)and non-photochemical quenching coefficient(qN).The soybeans in the seedling stage adapted to the inhibitory effect of drought stress on photosynthesis through stomatal limitation.Under serious drought stress,non-stomatal limitation damaged the plant photosynthetic system.The amplitudes of Pn and Y(II)of drought-resistant Qihuang 35 were lower than those of the two other varieties.Based on the data of this study,a new method had been developed to detect Y(II)which reflected the photosynthetic capacity of plant,R=0.85989,u=0.048803 when using multiple linear regression,and R=0.84285,u=0.054739 when using partial least square regression. | Wensen Wang Cheng Wang Dayu Pan Yakun Zhang Bin Luo Jianwei Ji | 2018 | International Journal of Agricultural and Biological Engineering2018，11，2： | 7 |
| 2 | Curcumin’s prevention of inflammation-driven early gastric cancer and its molecular mechanism显示文摘Worldwide,gastric cancer is the second leading cause of cancer deaths and the fifth most common malignant tumor.Gastric cancer is believed to be caused by a variety of factors,such as genetics,epigenetics,and environmental influences.Among the pathogenic factors,inflammation has been considered as one of the main risk factors for gastric cancer.There are currently limited ways to prevent gastric cancer.Although the combined application of aspirin and non-steroidal anti-inflammatory drugs can reduce the risk,it has great side effects and can easily cause gastric perforation or gastric bleeding.Therefore,an alternative plan is urgently needed.Curcumin is the yellow pigment in the rhizome of the plant turmeric.Current studies have found that curcumin has a protective effect on gastric mucosal damage caused by non-steroidal anti-inflammatory drugs,gastric mucosal damage in rats,and gastric mucosal damage caused by stress bleeding and Helicobacter pylori infection.Curcumin shows significant antiinflammatory and anti-cancer activities by regulating DNA methylation,histone modification,nuclear factor erythrocyte 2 related factor 2 and other related signal pathways.In this article,the latest evidence of curcumin for epigenetic changes in gastric cancer and its potential contribution to gastric cancer were discussed. | Wensen Zhang Na Cui Jin Ye Bingyou Yang Yanping Sun Haixue Kuang | 2022 | Chinese Herbal Medicines2022，14，2： | 3 |
| 3 | 3D-printed models improve surgical planning for correction of severe postburn ankle contracture with an external fixator显示文摘Gradual distraction with an external fixator is a widely used treatment for severe postburn ankle contracture(SPAC).However,application of external fixators is complex,and conventional two-dimensional(2D)imaging-based surgical planning is not particularly helpful due to a lack of spatial geometry.The purpose of this study was to evaluate the surgical planning process for this procedure with patient-specific three-dimension-printed models(3DPMs).In this study,patients coming from two centers were divided into two cohorts(3DPM group vs.control group)depending on whether a 3DPM was used for preoperative surgical planning.Operation duration,improvement in metatarsal-tibial angle(MTA),range of motion(ROM),the American Orthopedic Foot and Ankle Society(AOFAS)scores,complications,and patient-reported satisfaction were compared between two groups.The 3DPM group had significantly shorter operation duration than the control group((2.0±0.3)h vs.(3.2±0.3)h,P<0.01).MTA,ROM,and AOFAS scores between the two groups showed no significant differences pre-operation,after the removal of the external fixator,or at follow-up.Plantigrade feet were achieved and gait was substantially improved in all patients at the final follow-up.Pin-tract infections occurred in two patients(one in each group)during distraction and were treated with wound care and oral antibiotics.Patients in the 3DPM group reported higher satisfaction than those in the control group,owing to better patient-surgeon communication.Surgical planning using patient-specific 3DPMs significantly reduced operation duration and increased patient satisfaction,while providing similar improvements in ankle movement and function compared to traditional surgical planning for the correction of SPAC with external fixators. | Youbai CHEN Zehao NIU Weiqian JIANG Ran TAO Yonghong LEI Lingli GUO Kexue ZHANG Wensen XIA Baoqiang SONG Luyu HUANG Qixu ZHANG Yan HAN | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，10： | 3 |
| 4 | Regulation of the radiosensitivity of tumor cells through HIF-1α dependent intracellular redox status after fractionated radiation显示文摘Tumor cells often develop resistance to radiotherapy by fractionated radiation possibly due to the heterogeneity and hypoxia in tumor tissue.However,the mechanism of refractory effect remains unclear.In the present study,a radioresistant variant HepG2/R60 cell line was isolated from human HepG2 cells by repeated exposure to radiation.The results showed that,after irradiation,the higher survival rate was in HepG2/R60 cells compared to parental cells.Hypoxia treatment could further increase the radioresistance of HepG2/R60 cells concomitant with high level of intracellular GSH and overexpression of HIF-1α.When hypoxic HepG2/R60 cells were pretreated with BSO,a GSH depleter,the refractory response was significantly reduced showing a decrease in intracellular GSH level,followed by the suppression of HIF-1α in hypoxic cells.Subsequent study found that the level of BCL-2 was down-regulated,targeted by HIF-1 prompting transcription in hypoxic cells.The effect of HIF-1α on the radiosensitivity of hypoxic cells was confirmed using YC-1,a specific inhibitor of HIF-1α.Consequently,our results suggest that the radiosensitivity of tumor cells might be regulated by fractionated radiation,and the radioresistance of cells induced by repeated exposure,under hypoxic condition,could be correlated with overexpression of HIF-1α dependent on the alteration of intracellular GSH contents. | JIN Wensen KONG Zhaolu SHEN Zhifen JIN Yizun ZHANG Wukui | 2010 | Nuclear Science and Techniques2010，21，5： | 2 |
| 5 | Tree-ring δ^(15)N of Qinghai spruce in the central Qilian Mountains of China:Is pre-treatment of wood samples necessary?显示文摘A knowledge of the tree-ring stable nitrogen isotope ratio(δ^(15)N)can deepen our understanding of forest ecosystem dynamics by indicating the long-term availability,cycling and sources of nitrogen(N).However,the radial mobility of N blurs the interannual variations in the long-term N records.Previous studies of the chemical extraction of tree rings before analysis had produced inconsistent results and it is still unclear whether it is necessary to pre-treat wood samples from specific tree species to remove soluble N compounds before determining theδ^(15)N values.We compared the effects of pre-treatment with organic solvents and hot ultrapure water on the N concentration andδ^(15)N of tree rings from endemic Qinghai spruce(Picea crassifolia)growing in the interior of the central Qilian Mountains,China,during the last 60 a.We assessed the effects of different preparation protocols on the removal of the labile N compounds and investigated the need to pre-treat wood samples before determining theδ^(15)N values of tree rings.Increasing trends of the tree-ring N concentration were consistently observed in both the extracted and unextracted wood samples.The total N removed by extraction with organic solvents was about 17.60%,with a significantly higher amount in the sapwood section(P<0.01).Theδ^(15)N values of tree rings decreased consistently from 1960 to 2019 in both the extracted and unextracted wood samples.Extraction with organic solvents increased theδ^(15)N values markedly by about 5.2‰and reduced the variations in theδ^(15)N series.However,extraction with hot ultrapure water had little effect,with only a slight decrease in theδ^(15)N values of about 0.5‰.Our results showed that the radial pattern in the inter-ring movement of N in Qinghai spruce was not minimized by extraction with either organic solvents or hot ultrapure water.It is unnecessary to conduct hot ultrapure water extraction for the wood samples from Qinghai spruce because of its negligible effect on the removal of the labile N.Theδ^(15)N variation trend of tree rings in the unextracted wood samples was not influenced by the heartwood-sapwood transition zone.We suggest that theδ^(15)N values of the unextracted wood samples of the climate-sensitive Qinghai spruce could be used to explore the ecophysiological dynamics while focusing on the long-term variations. | WANG Ziyi LIU Xiaohong WANG Keyi ZENG Xiaomin ZHANG Yu GE Wensen KANG Huhu LU Qiangqiang | 2022 | Journal of Arid Land2022，14，6： | 1 |
| 6 | Lipase-catalyzed synthesis of phytostanyl esters in non-aqueous media显示文摘 | Wensen He Chengsheng Jia Yuan Ma Yebo Yang Xiaoming Zhang Biao Feng Lin Yue | 2010 | B, Enzymatic2010，，1： | 1 |
| 7 | Ultra-broadband,fast,and polarization-sensitive photoresponse of low-symmetry 2D NdSb_(2)显示文摘Broadband photodetectors with polarization-sensitive ability have received extraordinary attention for modern optoelectronic devices.Ideal photodetectors should possess high responsivity,fast response,and good stability,which are rare to meet at the same time in one low-symmetric two-dimentional(2D)material.In this work,neodymium diantimonides(RSb_(2)),a member of light rare-earth diantimonides RSb_(2)(R=La–Nd,Sm)with low-symmetry structure,is introduced as a fascinating highly anisotropic 2D material for broadband detection(532 nm to 4μm).The photodetector exhibits a responsivity of 0.49 mA·W^(−1)with 15μs response time at 532 nm and highly stable performance under ambient conditions over 8 months.Furthermore,we identify the polarization-sensitive photoresponse of the detector and demonstrate a high anisotropic factor~1.6.In addition,strong inplane anisotropy is revealed by anisotropic phonon response and the photodetection mechanism is investigated by scanning photocurrent microscopy measurements.This pioneer work on RSb_(2)paves the way for further exploration of 2D RSb_(2)for high performance polarized photodetectors with fast photothermoelectric response. | Gang Li Hanlin Zhang Yong Li Shiqi Yin Xucai Kan Wensen Wei Haifeng Du Binghui Ge Chao An Mingliang Tian Feng Yan Sanjun Yang Tianyou Zhai Liang Li | 2022 | Nano Research2022，15，6： | 1 |
| 8 | A novel implementation of SVPWM algorithm and its applicationto three-phase power converter 显示文摘 | Zhang Xiaowei Li Yongdong Wang Wensen | 2000 | Power Electronics and Motion Control Conference2000，，3： | 1 |
| 9 | Detection of Serum Gastric Cancer-Associated MG7-Ag from Gastric Cancer Patients Using a Sensitive and Convenient ELISA Method显示文摘 | Bin Jin Xin Wang Yan Jin Wensen Xia Bei Chen Lin Liu Zheng Chen Liu Hong Wenqi Du Kun Yan Honghong Wang Donghong Yuan Xiaoli Hui Li He Faming Zhang Yunping Zhao Kaichun Wu Daiming Fan | 2009 | Cancer Investigation2009，，2： | 1 |
| 10 | Evaluation of the Acute Toxicity of Prochloraz-manganese Chloride Complex to Environmental Species显示文摘[Objectives] This study was conducted to evaluate the toxicity risk of prochloraz-manganese chloride complex to environmental organisms. [Methods] The acute toxicity tests of prochloraz-manganese chloride complex on 8 common environmental organisms, such as Coturnix coturnix japonica, Apis mellifera L., Eisenia foetida, Bombyx mori, Trichogramma japonicum, Brachydanio rerio, Daphnia magna Straus and Scenedesmus obliquus were carried out. [Results] Prochloraz-manganese chloride complex to D. magna EC50(48 h): 1.11 mg a.i./L, with a 95% confidence limit of 1.00-1.26 mg a.i./L;B. rerio LC50(96 h): 2.84 mg a.i./L, with a 95 % Confidence limit of 2.43-3.48 mg a.i./L;S. obliquus ErC50(72 h): 1.88×10^-2 mg a.i./L, with a 95% confidence limit of 1.70×10^-2-2.16×10^-2 mg a.i./L;C. coturnix LD50(168 h): 1.01×10^3 mg a.i./kg body weight, with a 95% confidence limit of 7.87×10^2-1.27×10^3 mg a.i./kg body weight;T. japonicum LR50(24 h): 2.53×10^-3 mg a.i./cm^2, with a 95% confidence limit of 2.14×10^-3-2.99×10^-3 mg a.i./cm^2;B. mori LC50(96 h): 2.03×10^2 mg a.i./L, with a 95% confidence limit of 1.79×10^2-2.30×10^2 mg a.i./L;A. mellifera(peroral) LD50(48 h)>100 μg a.i./bee;A. mellifera(contact) LD50(48 h)>100 μg a.i./bee;E. foetida LC50(14 d)>1.00×10^2 mg a.i./kg dry soil. According to the Guidance for Evaluating and Calculating Degradation Kinetics in Environmental Media for Pesticide Registration, prochloraz-manganese chloride complex had low toxicity to A. mellifera, C. coturnix, B. mori and E. foetida, medium toxicity to D. magna and B. rerio, and high toxicity and low risk to S. obliquus and T. japonicum. [Conclusions] This study provides a data basis for the toxicity and environmental safety evaluation of the agent. | Xuye ZHANG Ji MA Xuanqing KONG Kuai YU Xiaojun DENG Wensen OUYANG Yu JIANG Xiaoming OU Chenzhong JIN | 2021 | Agricultural Biotechnology2021，10，1： | 0 |
| 11 | Investigations on MBSE modelling and dynamic performance assessment of an electrical trimmable horizontal stabilizer actuator显示文摘With the development of power-by-wire technology for more electric aircraft,the electromechanical actuator(EMA)has the advantages to replace the conventional hydraulic servo actuator in some aerospace flight controls.Conventional hydraulically powered trimmable horizontal stabilizer actuation(THSA)system is nowadays developed to be electrically supplied.Given their safety-criticality,no-back mechanism and redundant load paths are utilized to meet the flight control requirements.However,rare literatures have introduced these functions and addressed the virtual prototyping activities from system-level point of view.This paper proposed such a model of a THSA system with dual electric power sources and fault-tolerant mechanical load paths.The nonlinear effects of components are considered with realism,and system-level simulation test is conducted to support the model-based system engineering(MBSE)approach.The models are developed with a power view instead of a pure signal view.Focusing on the friction effect and compliance effect with backlash or preload,some improved and novel approaches are adopted for these crucial components and validated via experimental results.Meanwhile,the implemented systemlevel model enables injection of crucial faults.Finally,the simulation of the proposed model shows that it is an efficient resource to investigate the actuator’s dynamic performance,to virtually prove that the actuator meets the fail/safe constraint,and to demonstrate the soundness of the fault monitoring functions. | Wensen ZHANG Jian FU Jean-Charles MARÉ Haolin MA Tianxiang XIA Yongling FU Jiangao ZHAO | 2023 | Chinese Journal of Aeronautics2023，36，11： | 0 |
| 12 | Changes in photosynthesis and chlorophyll fluorescence in two soybean (Glycine max) varieties under NaCl stress显示文摘Traditional detection methods of crop information are often destructive and low efficiency.In this study,a new evaluation method was developed based on photosynthesis and chlorophyll fluorescence.Via analysis of the changes under NaCl stress during the seedling stage of two varieties,the salt resistance mechanism of soybeans was explored and a non-destructive stress-recognition method was developed.In this experiment,two soybean varieties were treated with one of four levels of NaCl stress:CK(0 mmol/L),LS(50 mmol/L),MS(100 mmol/L),and HS(150 mmol/L),for 15 d.The normal functions of the photosynthetic system of soybeans were enhanced under LS NaCl stress,but were inhibited under HS NaCl stress.Biomass,net leaf photosynthetic rate(Pn),stomatal conductance(gs),intercellular carbon dioxide concentration(Ci),transpiration rate(Tr),chlorophyll fluorescence parameters Y(II)and PSII decreased.However,in contrast to the findings of other studies on the influence of severe drought stress on soybean for long periods in which non-photochemical quenching coefficient(qN)decreased,this parameter increased under salt stress in soybean.The results demonstrate that the method developed is a promising tool for rapid and non-destructive detection of soybean photosynthetic responses under salt stress in the field. | Bin Luo Cheng Wang Xiaodong Wang Han Zhang Yanan Zhou Wensen Wang Peng Song | 2021 | International Journal of Agricultural and Biological Engineering2021，14，3： | 0 |
| 13 | Long-term mercury variations in tree rings of the permafrost forest,northeastern China显示文摘Permafrost is a potential mercury(Hg)pool released by thawing,which can raise the risk of Hg pollution under global warming.Tree rings are useful archives of environment-specific Hg exposure over long periods.We determined Hg concentrations in tree rings of two dominant tree species(Larix gmelinii Rupr.and Pinus sylvestris var.mongolica)at permafrost sites in northeastern China.The biweighted mean Hg concentrations ranged from 0.36 to 3.96 ng g^(-1) from 1840 to 2014.The tree-ring width had no significant influence on the Hg concentration.Larch Hg increased slightly before the 1970 s and peaked in the 1990 s.However,the pine Hg concentration increased continuously until the 1930 s,decreased rapidly until the 1970 s,then rose to a peak in the late 1980 s.The change of Hg concentrations in larch and pine revealed a time offset of 4 to 5 years,which implied possibly high mobility of Hg in pine tree rings.Higher Hg concentrations from 1920 to 1960 and subsequent decreases in isolated permafrost forests revealed the local geographical Hg cycling history.Lower Hg concentrations and faster increases in larch suggest the role of additional winter Hg loading for the evergreen pine and species-specific differences in root absorption in response to melting permafrost.Our results highlight possible geographical impacts on tree-ring Hg records,improve understanding of Hg cycles in permafrost forest,and suggest a need to sample additional species in a range of permafrost environments. | Huhu KANG Xiaohong LIU Junming GUO Qiuliang ZHANG Yabo WANG Jie HUANG Guobao XU Guoju WU Wensen GE Shichang KANG | 2022 | Science China Earth Sciences2022，65，7： | 0 |
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