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| 1 | Late Eocene pollen records and palaeoenvironmental changes in northern Tibetan Plateau显示文摘The Eocene palaeovegetation landscape and palaeoclimate reconstructed from the pollen records in the Jiuquan Basin, northwest China provide some important information on the early uplift of the Tibetan Plateau and the origin and evolution of the aridification in northwest China. The records show the arid-semiarid scrubs with open forest palynofloras controlled by the subtropical high existed in northwest China during the 40.2-33.4 Ma. Four pollen assemblages are found: Nitrariadites-Cheno-podipollis-Pinaceae assemblage (40.2-37.9 Ma) is followed by Chenopodipollis-Nitrariadites assemblage (37.9-34.6 Ma), Pinuspollenites & Abietineaepollenites-Chenopodipollis assemblage (34.6-33.9 Ma), and Chenopodipollis-Nitrariadites assemblage (33.9-33.4 Ma). The percentage of thermophilic types is in anti-correlation with that of the dry types, which means the palaeoclimate is relatively warmwet or cold-dry during most of that time. Such aridity may be related to the water vapor reduction and the planetary wind system movement northward in response to the cooling caused by small-ephemeral icesheets. | MIAO YunFa FANG XiaoMin SONG ZhiChen WU FuLi HAN WenXia DAI Shuang SONG ChunHui | 2008 | Science China Earth Sciences2008,51,8: | 10 |
| 2 | The FGOALS climate system model as a modeling tool for supporting climate sciences:An overview显示文摘Climate system models are useful tools for understanding the interactions among the components of the climate system and predicting/projecting future climate change. The development of climate models has been a central focus of the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics, Institute of Atmospheric Physics, Chinese Academy of Sciences(LASG/IAP) since the establishment of the laboratory in 1985. In China, many pioneering component models and fully coupled models of the climate system have been developed by LASG/IAP. The fully coupled climate system developed in the recent decade is named FGOALS(Flexible Global Ocean-Atmosphere-Land System Model). In this paper, an application-oriented review of the LASG/IAP FGOALS model is presented. The improved model performances are demonstrated in the context of cloud-radiation processes, Asian monsoon, ENSO phenomena, Atlantic Meridional Overturning Circulation(AMOC) and sea ice. The FGOALS model has contributed to both CMIP5(Coupled Model Intercomparison Project-phase 5) and IPCC(Intergovernmental Panel on Climate Change) AR5(the Fifth Assessment Report). The release of FGOALS data has supported the publication of nearly 500 papers around the world. The results of FGOALS are cited ~106 times in the IPCC WG1(Working Group 1) AR5. In addition to the traditional long-term simulations and projections, near-term decadal climate prediction is a new set of CMIP experiment, progress of LAGS/IAP in the development of nearterm decadal prediction system is reviewed. The FGOALS model has supported many Chinese national-level research projects and contributed to the national climate change assessment report. The crucial role of FGOALS as a modeling tool for supporting climate sciences is highlighted by demonstrating the model's performances in the simulation of the evolution of Earth's climate from the past to the future. | TianJun Zhou Bin Wang YongQiang Yu YiMin Liu WeiPeng Zheng LiJuan Li Bo Wu PengFei Lin Zhun Guo WenMin Man Qing Bao AnMin Duan HaiLong Liu XiaoLong Chen Bian He JianDong Li LiWei Zou XiaoCong Wang LiXia Zhang Yong Sun WenXia Zhang | 2018 | Earth and Planetary Physics2018,2,4: | 6 |
| 3 | ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer显示文摘The Serine-Glycien-One-Carbon(SGOC)pathway is pivotal in multiple anabolic processes.Expression levels of SGOC genes are deregulated under tumoeigenic condltions,suggesting panicipation of oncogenes in deregulating the SGOC biosynthetic pathway.However,the underlying mechanism remains elusive.Here,we identifed that Interleukin enfiarccer-binding factor 3(ILF3)is overexpressed in primary CRC patient specimens and correlates with poor progroosis.ILF3 is critical in regulating the SGOC pathway by directly regulating the mRNA stability of SGOC genes,thereby increasing SGOC genes expression and facilitating tumor growth.Mehhanktic studies showed that the EGF-MIEK-ERK pathway nnediates ILF3 phosphorylation,which hin ders E3 ligase speckle-type POZ protein(SPOP)-mediated poly-ubiquitination and degradation of ILF3.Sign iftca ntly,combination of SGOC inhibitor and the anti-EGFR monoclonal antibody cetuximab can hinder the growth of patient-derived xenografts that sustain high ERK-ILF3 levels.Taken together,deregutation of ILF3 via the EGF-ERK signaling plays an important role in systemic serine metabolic reprogramming and confers a predilection toward CRC development.Our findings indicate that clinical evaluation of SCOC inhibitor is warranted for CRC patients with ILF3 overexpression. | Kai Li Jian-lin Wu Baifu Qin Zongmin Fan Qin Tang Weisi Lu Haipeng Zhang Fan Xing Manqi Meng Shaomin Zou Wenxia Wei Honglei Chen Jian Cai Huaiming Wang Hui Zhang Jiayue Cai Ling Fang Xiqing Bian Chuangqi Chen Ping Lan Bart Ghesquiere Lekun Fang Mong-Hong Lee | 2020 | Cell Research2020,30,2: | 6 |
| 4 | Dual pH and glucose sensitive gel gated mesoporous silica nanoparticles for drug delivery显示文摘A low molecular weight gelator with dual pH and glucose sensitive moieties was synthesized. The gelator penetrated in the mesopores of silica nanoparticles(MSNs) and formed low molecular weight gel(LMWG) as gate to fabricate dual pH and glucose responsive nano drug delivery system. Antidiabetic drug was loaded in the gel caped MSNs, the drug release was responsive to the pH and glucose levels and the drug release could be controlled via the stimuli sensitivity of gel. | Wenxia Gao Yalong Hu Long Xu Miaochang Liu Huayue Wu Bin He | 2018 | Chinese Chemical Letters2018,29,12: | 4 |
| 5 | A photocleavable low molecular weight hydrogel for light-triggered drug delivery显示文摘A photocleavable low-molecular-weight hydrogelator (LMWG) was synthesized based on coumarin derivative.~1H NMR and UV spectroscopy study suggested that the gelator had good gelling ability, and the driving force for the gelation were hydrogen bonding and π-π stacking. This molecular hydrogel exhibited satisfied photocleavage at C-N bond in 7-amino coumarin with the light irradiation (365 nm,77.5 mW/cm^2). The promising photo-triggered drug release of antineoplastics cytarabine hydrochloride has been obtained, due to the photocleavage motived gel-sol transition. | Qihong Liu Hao Wang Guotao Li Miaochang Liu Jinchang Ding Xiaobo Huang Wenxia Gao Huayue Wu | 2019 | Chinese Chemical Letters2019,30,2: | 4 |
| 6 | From unusual suspect to serial killer: Cyanotoxins boosted by climate change may jeopardize megafauna显示文摘The recent mass mortality event of more than 330 African elephants in Botswana has been attributed to biotoxins produced by cyanobacteria;however,scientific evidence for this is lacking.Here,by synthesizing multiple sources of data,we show that,during the past decades,the widespread hypertrophic waters in Southern Africa have entailed an extremely high risk and frequent exposure of cyanotoxins to the wildlife within this area,which functions as a hotspot of mammal species richness.The hot and dry climatic extremes have most likely acted as the primary trigger of the recent and perhaps also of prehistoric mass mortality events.As such climate extremes are projected to become more frequent in Southern Africa in the near future,there is a risk that similar tragedies may take place,rendering African megafauna species,especially those that are already endangered,in risk of extinction.Moreover,cyanotoxin poisoning amplified by climate change may have unexpected cascading effects on human societies.Seen within this perspective,the tragic mass death of the world's largest terrestrial mammal species serves as an alarming early warning signal of future environmental catastrophes in Southern Africa.We suggest that systematic,quantitative cyanotoxin risk assessments are made and precautionary actions to mitigate the risks are taken without hesitation to ensure the health and sustainability of the megafauna and human societies within the region. | Haijun Wang Chi Xu Ying Liu Erik Jeppesen Jens-Christian Svenning Jianguo Wu Wenxia Zhang Tianjun Zhou Puze Wang Shingirai Nangombe Jinge Ma Hongtao Duan Jingyun Fang Ping Xie | 2021 | The Innovation2021,2,2: | 3 |
| 7 | Micro and nanolattice fabrication using projection micro litho stereo exposure additive manufacturing techniques and synchrotron X-ray 3D imaging-based defect characterization显示文摘Synchrotron radiation X-ray micro-computed tomography(SR-μCT)is a 3D imaging technique that is widely employed for the characterization of defects in advanced materials and structures.In this study,we characterize several typical defects in octettruss and re-entrant 3D lattice structures by using SR-μCT.The 3D micro-lattice structures are manufactured using projection micro litho stereo exposure(PμLSE)additive manufacturing technology.The as-fabricated 3D lattice samples are characterized using optical microscopy,and subsequently,by SR-μCT.Further more,a statistical analysis is performed to characterize the surface roughness and internal defects qualitatively,whereby the statistical geometrical parameters of struts along different directions and strut joints are analyzed and classified.Consequently,several typical defects are identified:(1)holes at the joints of the strut and irregular diameter deviations of the strut in the octet-truss lattice structure;(2)irregular diameter variations,bulges,dislocations,grooves,accumulations,and torsion in the re-entrant lattice structure.All of these defects are related to the building direction,the weight of the structure,bubbles,dust,and impurities during the PμLSE additive manufacturing process. | HU WenXia LIU LiWu WU WenWang XI Li LENG JinSong FANG DaiNing | 2020 | Science China(Technological Sciences)2020,63,4: | 2 |
| 8 | Generative adversarial network-based atmospheric scattering model for image dehazing显示文摘This paper presents a trainable Generative Adversarial Network(GAN)-based end-to-end system for image dehazing,which is named the DehazeGAN.DehazeGAN can be used for edge computing-based applications,such as roadside monitoring.It adopts two networks:one is generator(G),and the other is discriminator(D).The G adopts the U-Net architecture,whose layers are particularly designed to incorporate the atmospheric scattering model of image dehazing.By using a reformulated atmospheric scattering model,the weights of the generator network are initialized by the coarse transmission map,and the biases are adaptively adjusted by using the previous round's trained weights.Since the details may be blurry after the fog is removed,the contrast loss is added to enhance the visibility actively.Aside from the typical GAN adversarial loss,the pixel-wise Mean Square Error(MSE)loss,the contrast loss and the dark channel loss are introduced into the generator loss function.Extensive experiments on benchmark images,the results of which are compared with those of several state-of-the-art methods,demonstrate that the proposed DehazeGAN performs better and is more effective. | Jinxiu Zhu Leilei Meng Wenxia Wu Dongmin Choi Jianjun Ni | 2021 | Digital Communications and Networks2021,7,2: | 1 |
| 9 | Improvement of in situ LA-ICP-MS U-Pb dating method for carbonate minerals and its application in petroleum geology显示文摘In situ carbonate U-Pb dating is gaining popularity,and it has great potential for application in petroleum geology.However,the low U content(<10μg/g)and high common Pb content of carbonate minerals,along with the uneven distribution of U and Pb and the lack of matrix-matched reference material make carbonate U-Pb dating inaccurate and less successful,which limits the widespread application in geosciences.This study evaluated the limitations of in situ carbonate U-Pb dating and proposed a method to rationally determine the laser ablation parameters of samples by improving the experimental approach based on the laser ablation sector field inductively coupled plasma mass spectrometry(LA-SF-ICP-MS).By setting a different spot size and laser frequency for the reference material and unknown samples in the same session based on the U content of the sample,the ablation craters of the reference material and unknown samples were given the same depth/width ratio,avoiding systematic offset caused by differences in down-hole element fractionation and reducing the consume of reference material.Depending on the heterogeneous distribution of U and Pb contents in carbonate minerals,the method of grid screening and setting ablation spots during screening were used to quickly select domains with high U and low common Pb,which improves the efficiency of setting laser spots and the success rate of dating,as well as reduces the experimental time and economic cost.The accuracy and success rate of carbonate U-Pb dating were effectively improved by improving the experimental method,and the technique was applied to two carbonate samples with low U and high common Pb contents that were difficult to date by traditional methods.The two samples are the saddle dolomite in the central Sichuan Basin and the calcite cement in the sandstone reservoir of the Cretaceous Qingshuihe Formation in the South Junggar Basin.The robust ages have been obtained,which constrains the timing of the diagenetic and hydrocarbon accumulation process in the studied area. | Xuesong Lu Lili GUI Weiyan CHEN Shaobo LIU Shitou WU Junjia FAN Qiang LIU Jing SUN Liangliang ZHANG Yang XIAO Wenxia YANG Rizhou CAO | 2023 | Science China Earth Sciences2023,66,12: | 1 |
| 10 | Damage evolution of PμLSE additive-manufactured micro-lattice metastructures: Synchrotron radiation 3D tomography image-based analysis显示文摘The manufacturing of additives with projection micro litho stereo exposure(PμLSE)has provided an opportunity for the fabrication of metastructures with complex microstructures at micro-nano resolutions.However,the performance evaluation of as-fabricated metastructures is challenging.The benefit of synchrotron radiation-based 3 D imaging techniques and advanced image processing methods makes it is feasible to study fabrication defects and damage processes of micro-nanoscale bodycentered cubic(BCC)lattices manufactured with PμLSE.First,synchrotron radiation technology is used to capture the structural features inside the micro-lattice samples.Subsequently,several types of statistical defects-based image finite element models are adopted to analyze the failure process of the structure under compression loading.Finally,comparisons between in situ experiments and numerical simulation results are performed for verification.The method of the combined non-destructive testing of synchrotron radiation and image finite element technology provides a robust technique for evaluating the performances of additive-manufactured micro-lattice with complex microstructures. | QingLiang Zeng WenWang Wu WenXia Hu Li Xi Ran Tao DaiNing Fang | 2020 | Science China(Physics,Mechanics & Astronomy)2020,63,10: | 1 |
| 11 | Experimental Study on the Thermal Argon Plasma Generation and Jet Length Change Characteristics at Atmospheric Pressure显示文摘 | Wenxia Pan Xian Meng Chengkang Wu Xi Chen | 2006 | Plasma Chemistry and Plasma Processing2006,,4: | 1 |
| 12 | Generation of Long, Laminar Plasma Jets at Atmospheric Pressure and Effects of Flow Turbulence显示文摘 | Wenxia Pan Wenhua Zhang Wenhong Zhang Chengkang Wu | 2001 | Plasma Chemistry and Plasma Processing2001,,1: | 1 |
| 13 | Generation of Long, Laminar Plasma Jets at Atmospheric Pressure and Effects of Flow Turbulence显示文摘 | Wenxia Pan Wenhua Zhang Wenhong Zhang Chengkang Wu | 2001 | Plasma Chemistry and Plasma Processing2001,,1: | 1 |
| 14 | Investigation of laminar plasma cladding processing显示文摘 | Ma Wei Fei Qunxing Pan Wenxia and Wu Chengkang | 2006 | Applied Surface Science2006,252,: | 1 |
| 15 | Sufficiently diffused attachment of nitrogen arc by gasdynamic action显示文摘For realizing diffused anode attachment in pure nitrogen arcs, a special arc plasma generator was designed and combined with suitable working parameters such as gas flow rate and arc current. The anode has a flow-restrictor channel of 2.8 mm diameter and downstream expansion half-angle of 8°, with the purpose of creating a dispersed nitrogen-arc column by strong gasdynamic expansion effect. Results show that,when thermal blocking condition existed in the flow restrictor and the cathode cavity pressure was higher than that in the exit chamber by at least 9 k Pa, the action due to gasdynamic expansion could be much stronger than the self-magnetic contraction effect of the arc and the nitrogen arc column could be effectively dispersed to form a sufficiently diffused attachment on the water-cooled anode surface. | Wenxia Pan Lewen Chen Xian Meng Yong Zhang Chengkang Wu | 2016 | Theoretical & Applied Mechanics Letters2016,6,6: | 1 |
| 16 | Bulk GaN Single Crystals: Growth Conditions by Flux Method 显示文摘 | Youting Song Wenjun Wang Wenxia Yuan Xing Wu Xiaolong Chen | 2003 | J Crystal Growth2003,247,: | 1 |
| 17 | Study on quality components and sleep-promoting effect of GABA Maoyecha tea显示文摘 | Chunlan Wu Yahui Huang Xingfei Lai Ronghui Lai Wenxia Zhao Min Zhang Wenfang Zhao | 2014 | Journal of Functional Foods2014,,: | 1 |
| 18 | The Effect of Attendance Patterns on the Lek Mating System in the Omei Treefrog(Rhacophorus omeimontis)显示文摘Attendance patterns are a key factor affecting sexual selection and mating systems in lekbreeding species.However,there are few systematic studies on attendance patterns in lek-breeding anurans.In this study,we monitored a population of Omei treefrogs(Rhacophorus omeimontis) for four consecutive years to reveal in detail the effects of attendance patterns on mating systems.We found that(1) female nightly attendance was affected by male nightly attendance,and operational sex ratios(determined by male and female nightly attendance) ultimately determined the extent of female polyandry;(2) males surviving more than one breeding season maintained high chorus attendance and mating success,suggesting that male chorus attendance is a good predictor of male genetic quality;(3) the distributions of male mating success were not significantly different from a Poisson distribution,indicating a random mating pattern;and male mating success was not related to body size(size-assortative mating was not evident) but was significantly correlated with chorus attendance.Since the chorus attendance is a predictor of male genetic quality,females performing random mating were more likely to mate with more frequently present males and could therefore gain indirect benefits from mating with higher-than-average quality males,thereby producing good offspring without incurring the significant costs involved in prolonged searching for,and assessing males.Our systematic survey on the relationship between attendance patterns and the lek mating system in R.omeimontis could help us better understand in-depth anuran lek mating systems. | Yue GUO Wenxia WANG Wei ZANG Hui WANG Chenliang LI Mian ZHAO Hua WU | 2020 | Asian Herpetological Research2020,11,4: | 0 |
| 19 | Control of MSC Differentiation by Tuning the Alkyl Chain Length of Phe- nylboroinc Acid Based Low-molecular-weight Gelators显示文摘 | Jing He Yalong Hu Fang Wu Bin He Wenxia Gao | 2018 | Journal of Bionic Engineering2018,15,4: | 0 |
| 20 | Analysis of the valence electronic structures and calculation of the physical properties of Fe,Co,and Ni显示文摘The valence electronic structures of Fe, Co and Ni have been investigated with Empirical Electron Theory of Solids and Molecules. The magnetic moments, Curie temperature, cohesive energy and melting point have been calculated according to the valence electronic structure. These calculations fit the experimental data very well. Based on the calculations, the magnetic moments are proportional to the number of 3d magnetic electrons. Curie temperatures are related to the magnetic electrons and the bond lengths between magnetic atoms. Cohesive energies increase with the increase of the number of covalent electrons, and the decrease of the number of magnetic and dumb pair electrons. The melting point is mainly related to the number of covalent electron pairs distributed in the strongest bond. The contribution from the lattice electrons is very small, the dumb pair electrons weaken the melting point; however, the contribution to melting point of the magnetic electrons can be neglected. It reveals that the magnetic and thermal properties are closely related to the valence electronic structures, and the changes or transitions between the electrons obviously affect the physical properties. | WU WenXia XUE ZhiYong HONG Xing LI XiuMei GUO YongQuan | 2009 | Science China(Physics,Mechanics & Astronomy)2009,52,6: | 0 |