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| 1 | Expression of perforin and granzyme B mRNA in judgement of immunosuppressive effect in rat liver transplantation显示文摘AIM To explore the expression of perform andgranzyme B genes mRNA to judge the effect ofimmunosuppression in acute rejection of livertransplantation.METHODS The expression of perform andgranzyme B genes mRNA was examined byreverse transcriptase-polymerase chain reaction(RT--PCR) in hamster to rat liver grafts under theimmunosuppression of cyclosporine or/andsplenectomy. Histological findings were studiedcomparatively.RESULTS Cyclosporine could obviouslydecrease the cellular infiltration, and completelyrepress the expression of mRNA for perform andgranzyme B, but could not change severehepatocyte necrosis and hemorrhage.SPlenectomy could significantly lightenhepatocyte necrosis, and completely eliminatehemorrhage, but not atfect the cellularinfiltration and the expression of perform andgranzyme B genes mRNA. Cyclosporine orsplenectomy alone could not prolong theSurvival time, however, their combination couldcompletely repress the rejection of liver grafts.The survival time of animals were significantlyprolonged (37.1 days ). The architecture ofhepatic lobules was preserved. There was slightcellular infiltration in the portal tracts and noexpression of perform and granzyme B genesmRNA could be seen in three weeks aftertransplantation.CONCLUSION Perform and granzyme B genesare valuable in judging the effect ofimmunosuppression in liver transplantation. | Zhang SG Wu MC Tan JW Chen H Yang JM Qian QJ | 1999 | World Journal of Gastroenterology1999，5，3： | 15 |
| 2 | 男性迟发性性腺功能减退症的检查、治疗和监测:国际男科学会(ISA)、国际老年男性研究会(ISSAM)、欧洲泌尿外科学会(EAU)、欧洲泌尿外科学院(EAA)和美国男科学会(ASA)联合推荐显示文摘简介
人口学资料明确显示:老年人口占总人口的百分率正逐年增加。当前,有关老年男性雄激素缺乏的问题逐渐成为令人感兴趣、但又充满争议的世界性话题。已经有横向和纵向的研究资料表明,随着年龄增大,成年男子的雄激素水平逐渐降低, | Wang C Nieschlage E Swerdloff R Behre HM Hellstrom WJ Gooren LJ Kaufman JM Legros JJ Lunenfeld B Morales A Morley JE Schulman C Thompson IM Weidner W Wu FCW 伍学焱(翻译) | 2011 | 国际生殖健康/计划生育杂志2011，30，1： | 8 |
| 3 | Over expression of extracellular ma- trix metalloproteinase inducer in muhidrug resistant cancer cells 显示文摘 | Yang JM Xu Z Wu H | 2003 | Mol Cancer Res2003，1，： | 1 |
| 4 | Neuronal spec- ificity of acupuncture response : a fMRI study with electro- acupuncture显示文摘 | WU MT SHEEN JM CHUANG KH | 2002 | Neuroimage2002，16，4： | 1 |
| 5 | Analysis of the fungi community in multiple- and single-grains Zaopeifrom a Luzhou-flavor liquor distillery in western China 显示文摘 | Shi S Zhang L Wu ZY Zhang WX Deng Y Zhong FD Li JM | 2011 | World JMicrobiol Biotechnol2011，27，： | 1 |
| 6 | Association of in- creased interferon- inducible gene expression with disease activi- ty and lupus nephritis in patients with systemic lupus erythe-matosus显示文摘 | FENG X WU H GROSSMAN JM | 2006 | Arthritis & Rheumatism2006，54，9： | 1 |
| 7 | Chorioamnionitis as a risk factor for cerebral palsy:a meta-analysis显示文摘 | Wu YW Colford JM Jr | 2000 | JAMA2000，284，： | 1 |
| 8 | Treatment with high-dose methylprednisolone for hepatic veno-occlusive disease in a child with rhabdomyosarcoma显示文摘 | Chen IL Yang SN Hsiao CC Wu KS Sheen JM | 2008 | Pediatr Neonatol2008，49，4： | 1 |
| 9 | A cable-driven locomo- tor training system for restoration of gait in human SCI 显示文摘 | Wu M Hornby TG Landry JM | 2011 | Gait Posture2011，33，： | 1 |
| 10 | Chitosanmicrospheres as immobilized dye affinity support for catalase adsorption显示文摘 | SHENTU JL WU JM SONGWH etal | 2005 | lntJBiolMacromol2005，37，12： | 1 |
| 11 | Synthesis of'clean' and well-dispersive Pd nanopartlcles with excellent elcctrocatalytic property on graphene oxide 显示文摘 | ChenX M Wu G H Chen JM | 2011 | Journal of the American Chemical Society2011，133，11： | 1 |
| 12 | Amyloid beta-protein fragment 31- 35 suppresses long-term potentiation in hippocampal CA1 region of rats in vivo 显示文摘 | Zhang JM Wu MN Qi JS | 2006 | Synapse2006，60，4： | 1 |
| 13 | Classification and pathology 显示文摘 | Wu JM Montgomery E | 2008 | Surg Clin North Am2008，88，3： | 1 |
| 14 | Aclarubiein and low-dose cytosine arabinoside in combination with granulocyte colony-stimulating factor in treating acute myeloid leukemia patients with relapsed or refractory disease and myelody syndrome: a multicenter study of 112 chinese patients显示文摘 | Li JM Shen Y Wu DP | 2005 | Int J Hematol2005，82，1： | 1 |
| 15 | Sequential expression of recombinant proteins and their separate recovery from a Pichia pastoris cultivation 显示文摘 | Wu JM Chieng LL Hsu TA | 2003 | Bioehem Engi2003，16，1： | 1 |
| 16 | Laparoscopic versus open appendectomy for perforated appendicitis显示文摘 | Lin HF Wu JM Tseng LM | 2006 | J Gastrointest Surg2006，10，6： | 1 |
| 17 | Change of serum growth factors in infants with isolated ventricular defect undergoing surgical repair显示文摘 | Tsai TP Yu JM Wu YL Huang CY Chen FL | 2002 | Ann Whorac Surg2002，73，6： | 1 |
| 18 | Mechanism of cardioprotection by resveratrol, a phcnolic antioxidant present in red wine (review) 显示文摘 | Wu JM Wang ZR Hsieh TC | 2001 | Internat J Mol Med2001，8，1： | 1 |
| 19 | Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice显示文摘 | Wu JM Chen Y Chen JC | 2010 | Cancer Letters2010，287，2： | 1 |
| 20 | Laparoscopic appendectomy in pregnancy显示文摘 | Wu JM Chen KH Lin HF | 2005 | J Laparoendosc Adv Surg Tech A2005，15，5： | 1 |
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