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| 1 | The value of postoperative hepatic regional chemotherapy in prevention of recurrence after radical resection of primary liver cancer显示文摘INTRODUCTIONIn China,primary liver cancer (PLC) ranks secondin cancer mortality since the 1990s.In the field ofPLC treatment,surgical resection remains the best,which includes large PLC resection,small PLCresection,re-resection of subclinical recurrence,aswell as cytoreduction and sequential resection forunresectable PLC.However,recurrence | Wu ZQ Fan J Qiu SJ Zhou J Tang ZY | 2000 | World Journal of Gastroenterology2000，6，1： | 19 |
| 2 | Effects of combined splenorenal shunt devascularization and devascularization only on hemodynamics of the portal venous system in patients with portal hypertension显示文摘Shunt and devascularization have totally different effects on hemodynamics of the portal venous system , and the actual results of combined shunt and devascularization should be determined by more clinical observations. This study aimed to evaluate effects on hemodynamics of the portal venous system after conventional spleno-renal shunt combined with pericardial devascularization and pericardial devascularization only. METHODS: In 20 patients who had received conventional splenorenal shunt combined with pericardial devascularization(CP) and 18 who had received pericardial devascularization and splenectomy (PCDV), hemodynamic parameters of the portal venous system were studied by magnetic resonance angiography 1 week before and 2 weeks after operation. Free portal pressure was detected continuously by a transducer during the operation. RESULTS: Compared to the preoperative data, a decreased flow of the portal vein (PVF) (563.12±206.42 ml/min vs 1080.63±352.85 ml/min, P<0.05), a decreased diameter of the portal vein (PVD) (1.20±0.11 cm vs 1.30±0.16 cm, P<0.01 ), a decreased free portal preasure ( FPP ) (21.50±2.67 mmHg vs 29.88±2.30 mmHg, P<0.01) and an increased flow of the superior mesenteric vein (SMVF) (1105.45±309.03 ml/min vs 569.13±178.46 ml/min, P < 0.05) were found in the CP group after operation; a decreased PVD (1.27±0.16 cm vs 1.40±0.23 cm, P<0.05), a decreased PVF (684.60±165.73 ml/min vs 1175.64±415.09 ml/min, P<0.05), a decreased FPP (24.40±3.78 mmHg vs 28.80±3.56 mmHg, P<0.05) and an increased SMVF (697.91+121.83 ml/min vs 521.30±115.82 ml/min, P<0.05) were found in the PCDV group. After operation, the PVF of CP group (563.12±206.42 ml/min vs 684.60±165.73 ml/min, P>0.05) was not decreased significantly while FPP (21.50±2.67 mmHg vs 24.40±3.78 mmHg, P< 0.01) was decreased significantly as compared with that of the PCDV group. PVF and FPP could be decreased by both surgical procedures, but the effect of decreasing FPP is much better in the combined procedures than in PCDV. Since there is no significant difference in PVF between the two groups, the combined procedures could integrate advantages of shunt with those of the devascularization, maintaining the normal anatomy structure of the hepatic portal vein, and should be one of the best choices for patients with PHT when surgical interventions are considered. | Department of General Surgery, Renji Hospital, Shanghai 200127, China (Cao H, Hua R and Wu ZY) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 18 |
| 3 | Effect of metabolic structures and energy requirements on curdlan production by Alcaligenes faecalis显示文摘 | Zheng, ZY Lee, AW Zhan, XB Shi, Z Wang, L Zhu, L Wu, JR Lin, CC | 2007 | 中国生物学文摘2007，21，10： | 13 |
| 4 | Intrahepatic transplantation of hepatic oval cells for fulminant hepatic failure in rats显示文摘AIM:To evaluate the effect of intrahepatic transplantation of hepatic oval cells(HOC)on fulminant hepatic failure(FHF)in rats.METHODS:HOC obtained from rats were labeled with green fluocescent protein(GFP)or 5,6carboxyfluorescein diacetate succinmidyl ester(CFDASE).Cell fluorescence was observed under fluorescent microscope at 6,24,48 and 72 h after labeling.CFDASE labeled HOC(5×10 6 cells each rat)were injected into livers of rats with FHF induced by D-galactosamine.Serum albumin(ALB),alanine aminotransferase(ALT),aspartate aminotransferase(AST)and total bilirubin(TBil)levels were measured at different time points.Liver function of rats was examined on days 3,7,14 and 21 after HOC transplantation.RESULTS:The positive rate of GFP and CFDA-SE labeled HOC was 10%and 90%,respectively,with no significant change in cell viabilities.The survival rate was higher in HOC transplantation group than in control group,especially 48(9/15 vs 6/15)and 72 h(9/15 vs 4/15)after HOC transplantation.The serum ALT,AST and TBil levels were decreased while the serum Alb level was increased after HOC transplantation.Fluorescence became faded and diffused in liver tissues,suggesting that proliferation and differentiation occur in transplanted HOC.CONCLUSION:CFDA-SE is superior to GFP in labeling HOC,although fluorescence intensity is decreased progressively with cell division.HOC transplantation can improve the liver function and increase the survival rate of recipients. | Chen-Xuan Wu,Qi Zou,Zheng-Yan Zhu,Ying-Tang Gao,Yi-Jun Wang,Department of Hepatobiliary,The Third Center of Affiliated Hospital of Tianjin Medical University Key Laboratory of Artificial Cells of Tianjin,Tianjin 300170,China Author contributions:Wang YJ,Wu CH and Zou Q designed the research Zou Q,Zhu ZY,Gao YT performed the research Zou Q analyzed the data Wang YJ and Wu CX wrote the paper.Supported by Tianjin Science Committee,Grant No.05SYSYJC02600 and Tianjin Health Bureau,Grant No.05KYR01 | 2009 | World Journal of Gastroenterology2009，15，12： | 7 |
| 5 | Improved cryopreservation of human embryonic stem cells with trehalose显示文摘 | Wu CF Tsung HC Zhang W J Wang Y Lu JH Tang ZY Kuang YP Jin W Cui L Liu W Cao YL | 2006 | 中国生物学文摘2006，20，7： | 2 |
| 6 | Cloning and identification of an angiostatic molecule IP-10/crg-2显示文摘AIM To obtain human and murine cDNAsencoding IFN--y inducible protein 10 (lP--10) andcytokine responsive gene--2 (Crg-2).METHODS The encoding genes of lP-10 and Crg2 were amplified by RT--PCR from Cultured humanfibroblast cells and Balb/ c mouse liver treatedby IFN-y and TNF-a, respectively, and clonedinto plasmids of PUC19 and PGEM3Zf(+ ).RESULTS The nucleotide sequences ot theamplified DNA were confirmed by endonucleasesdigestion and sequencing.CONCLUSION Recombinant lP-10/ crg--2 geneclones with 306 hp and 314 hp inserts wereestablished for further research on biologicalactivities and ligands of hiP-10/mCrg--2. | Liu ZG Yang JH An HZ Wang HY He FT Han ZY Han Y Wu HP Xiao B Fan DM | 1999 | World Journal of Gastroenterology1999，5，3： | 2 |
| 7 | Role of ubiquitin-proteasome pathway in skeletal muscle wasting in rats with endotoxemia显示文摘 | Jiake Chai Yanqiu Wu Zhiyong Sheng (Zy Sheng) | 2003 | Critical Care Medicine2003，，6： | 2 |
| 8 | Vector-based RNAi approach to isoform-specific downregulation of vascular endothelial growth factor(VEGF)165 expression in human leukemia cells显示文摘 | Shen HL Xu W Wu ZY | 2007 | Leuk Res2007，31，： | 1 |
| 9 | T-cadherin-mediated cell growth regulation involves G2 phase arrest and requires p21 (CIP1/ WAF 1 ) expression 显示文摘 | Huang ZY Wu Y Hedrick N | 2003 | Mol Cell Biol2003，23，2： | 1 |
| 10 | The mechanism of epristeride against benign prostatic hyperplasia显示文摘 | Sun ZY Wu HY Wang MY Tu ZH | 1999 | Eur J Pharmacol1999，371，23： | 1 |
| 11 | The mechanism of epristeride against benign prostate hyperplasia显示文摘 | Sun ZY Wu HY Wang MY Tu ZH | 1999 | Eur J Pharmacol1999，371，： | 1 |
| 12 | Identification and analysis of mutations of the Wilson disease gene in Chinese population显示文摘 | Wu ZY Wang N Murong SX | | 中华医学杂志(英文版)0，，： | 1 |
| 13 | Analysis of the fungi community in multiple- and single-grains Zaopeifrom a Luzhou-flavor liquor distillery in western China 显示文摘 | Shi S Zhang L Wu ZY Zhang WX Deng Y Zhong FD Li JM | 2011 | World JMicrobiol Biotechnol2011，27，： | 1 |
| 14 | Prognostic implication of ezrin expres- sion in esophageal squamous cell carcinoma 显示文摘 | Xie JJ Xu LY Wu ZY | 2011 | J Surg Oncol2011，104，5： | 1 |
| 15 | Prognostic implication of ezrin expres- sion in esophageal squamous cell carcinoma 显示文摘 | Xie J J Xu LY Wu ZY | 2011 | J Surg Oncol2011，104，5： | 1 |
| 16 | Renewable amperometric immunosensor for Schistosoma japonicium antibody assay显示文摘 | Liu GD Wu ZY Wang SP | 2001 | Analytical Chemistry2001，73，： | 1 |
| 17 | AChinesedynamicconcept of psychiatricrehabilitation 显示文摘 | Wu ZY | 1995 | Dynamic Psychiatry1995，，： | 1 |
| 18 | Interaction of Qinghaosu (Artemisi- nin) with Cysteine Sulfhydryl Mediated by Traces of Non- Heme Iron显示文摘 | Wu Y Yue ZY Wu YL | 1999 | Angew Chem Int Ed Engl1999，38，17： | 1 |
| 19 | Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system显示文摘 | Yan SS Wu ZY Zhang HP | | 0，，3： | 1 |
| 20 | HIV-1 infection in commercial plasma donors in China 显示文摘 | Wu ZY | 1995 | Lancet1995，1，： | 1 |
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