|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Hepatocellular carcinoma HepG2 cell apoptosis and caspase-8 and Bcl-2 expression induced by injectable seed extract of Coix lacryma-jobi显示文摘BACKGROUND:Many Chinese herbs,especially herbal injections,have been shown to have anti-tumor effects in recent years.However,since most reports focus on the clinical effectiveness of these herbs,their mechanisms of action are not well understood.In this study,we assessed apoptosis in the hepatocellular carcinoma (HCC) cell line HepG2 induced by an injectable extract from the seed of Coix lacryma-jobi (Semen coicis,SC),and monitored the expression of Bcl-2 and caspase-8.METHODS:Injectable SC was applied to HepG2 cells at different concentrations and the cells were collected 12,24 and 48 hours later.5-fluorouracil was used as a positive control group,and fluorescence-activated cell-sorting cytometry was used to measure the apoptosis rate of HepG2 cells and the expression of Bcl-2 and caspase-8 proteins.RESULTS:SC induced apoptosis in HepG2 cells in a concentration and time-dependent manner,and the expression of caspase-8 was elevated and prolonged.However,it did not significantly influence the expression of Bcl-2.CONCLUSION:Injectable SC may induce apoptosis in HCC cells by regulating the expression of caspase-8. | Department of General Surgery (Lu Y and Zhang BY),Department of Bio-Information (Jia ZX),Affiliated Medical College Hospital,Qingdao University,Qingdao 266003,China Shanghai Jiaotong University School of Medicine,Shanghai 200025,China (Wu WJ) Department of Medicine,Heze Medical College,Heze 274000,China (Lu ZQ) | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 17 |
| 3 | Isolation and Structure Elucidation of Autolytimycin, A New Compound Produced by Streptomyces Autolyticus JX-47显示文摘Autolytimycin 1 was isolated from the culture filtrate of Streptomyces autolyticus JX-47, together with two known compounds, lebstatin 2 and 17-O-demethyl-geldanamycin 3. These compounds showed the activities of anti-HSV-I. The structure of 1 was determined by spectral analysis. | Li, MG Wu, SH Zhao, LX Zhang, Q Li, WJ Cui, XL Xu, LH Wu, DG Jiang, CL | 2001 | Chinese Chemical Letters2001，12，10： | 10 |
| 4 | 男性迟发性性腺功能减退症的检查、治疗和监测:国际男科学会(ISA)、国际老年男性研究会(ISSAM)、欧洲泌尿外科学会(EAU)、欧洲泌尿外科学院(EAA)和美国男科学会(ASA)联合推荐显示文摘简介
人口学资料明确显示:老年人口占总人口的百分率正逐年增加。当前,有关老年男性雄激素缺乏的问题逐渐成为令人感兴趣、但又充满争议的世界性话题。已经有横向和纵向的研究资料表明,随着年龄增大,成年男子的雄激素水平逐渐降低, | Wang C Nieschlage E Swerdloff R Behre HM Hellstrom WJ Gooren LJ Kaufman JM Legros JJ Lunenfeld B Morales A Morley JE Schulman C Thompson IM Weidner W Wu FCW 伍学焱(翻译) | 2011 | 国际生殖健康/计划生育杂志2011，30，1： | 8 |
| 5 | Vitamin K3-induced cell cycle arrest and apoptosis cell death are accompanied by altered expression of c-fos and c-myc in nasopharyngeal carcinoma cells显示文摘 | Wu FY Chang NT Chen WJ | 1993 | Oncogene1993，8，8： | 2 |
| 6 | Early renal replacement therapy in patients with postoperative acute liver failure associated with acute renal failure effect on postoperative outcomes 显示文摘 | Wu VC Ko WJ Chang HW | 2007 | J Am Coil Surg2007，205，2： | 1 |
| 7 | Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor - induced HepG2 cell invasion involving both MAPK/ERKs and PI3K -Akt pathways 显示文摘 | Lee WJ Wu LF Chen WK | 2006 | Chem Biol Interact2006，160，2： | 1 |
| 8 | Aseptic nonunion of a femoral shaft treated using exchange nailing 显示文摘 | Yu CW Wu CC Chen WJ | 2002 | Chang Gung Med J2002，25，9： | 1 |
| 9 | Quiescent infected nonunion of a tibia treated by intramedullary reaming with external fixation 显示文摘 | Wu CC Shih CH Chen WJ | 1997 | J Orthop Surg( Hong Kong)1997，5，： | 1 |
| 10 | Recent advances in understanding aminoglycoside ototoxicity and its prevention显示文摘 | Wu WJ Sha SH Schacht J | 2002 | Audiol Neurootol2002，7，： | 1 |
| 11 | Predicting tissue outcome in acute human cerebral ischemia using combined diffusion - and perfusion - weighted MR imaging 显示文摘 | Wu O Koroshetz WJ Ostergaard L | 2001 | Stroke2001，32，4： | 1 |
| 12 | Aseptic nonunion of a femoral shaft treated using exchange nailing 显示文摘 | Yu CW Wu CC Chen WJ | 2002 | Chang Gung Med J2002，25，9： | 1 |
| 13 | Therapeutic efficacy of bipolar plasmakinetic technique compared with transurethral resection on benign prostate hyperplasia 显示文摘 | Wu WJ Wang XH Wang HP | 2005 | Zhonghua Yi Xue Za Zhi2005，85，47： | 1 |
| 14 | Visfatin-induced expression of inflammatory mediators in human endothelial cells through the NF-kappa B pathway显示文摘 | Lee WJ Wu CS Lin H | | 0，，： | 1 |
| 15 | Transport of dicationic drugs pentami dine and furamidine by human organic cation transporters显示文摘 | Ming X Ju WJ Wu HL Tidwell RR Hall JE Thakker DR | 2009 | Drug Metab Dispos2009，37，2： | 1 |
| 16 | 13-phenylethyl isothiocyanate reverses platinum resistance by a GSH-dependent mechanism in cancer cells with epithelial-mesenchymal transition phenotype 显示文摘 | Wu WJ Zhang Y Zeng ZL | 2013 | Biochem Pharmacol2013，85，4： | 1 |
| 17 | Combined anterior and posterior surgeries in the treatment of spinal tuberculous spondylitis显示文摘 | Chen WJ Wu CC Jung CH | | 0，，： | 1 |
| 18 | Evidence for an essential role of cyclooxygenase- 2 as a mediator of the late phase of ischemic preconditioning in mice显示文摘 | Guo Y Bao W Wu wJ | 2000 | Basic Res Cardiol2000，95，6： | 1 |
| 19 | Molecular characteristics of methicillinresistant Staphylococcus aureus isolated from Chinese children 显示文摘 | Liu YC Geng WJ Wu DJ ei al | 2012 | FEMS Immunol Med Microbiol2012，50，1： | 1 |
| 20 | TNF-308 G/A polymorphism and risk of aene vulgaris : a meta-analysis 显示文摘 | Yang JK Wu WJ Qi J | 2014 | PLoS One2014，9，87： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员