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| 1 | China land soil moisture EnKF data assimilation based on satellite remote sensing data显示文摘Soil moisture plays an important role in land-atmosphere interactions. It is an important geophysical parameter in research on climate, hydrology, agriculture, and forestry. Soil moisture has important climatic effects by influencing ground evapotranspi ration, runoff, surface reflectivity, surface emissivity, surface sensible heat and latent heat flux. At the global scale, the extent of its influence on the atmosphere is second only to that of sea surface temperature. At the terrestrial scale, its influence is even greater than that of sea surface temperatures. This paper presents a China Land Soil Moisture Data Assimilation System (CLSMDAS) based on EnKF and land process models, and results of the application of this system in the China Land Soil Moisture Data Assimilation tests. CLSMDAS is comprised of the following components: 1) A land process mo del—Community Land Model Version 3.0 (CLM3.0)—developed by the US National Center for Atmospheric Research (NCAR); 2) Precipitation of atmospheric forcing data and surface-incident solar radiation data come from hourly outputs of the FY2 geostationary meteorological satellite; 3) EnKF (Ensemble Kalman Filter) land data assimilation method; and 4) Observa tion data including satellite-inverted soil moisture outputs of the AMSR-E satellite and soil moisture observation data. Results of soil moisture assimilation tests from June to September 2006 were analyzed with CLSMDAS. Both simulation and assimila tion results of the land model reflected reasonably the temporal-spatial distribution of soil moisture. The assimilated soil mois ture distribution matches very well with severe summer droughts in Chongqing and Sichuan Province in August 2006, the worst since the foundation of the People’s Republic of China in 1949. It also matches drought regions that occurred in eastern Hubei and southern Guangxi in September. | SHI ChunXiang XIE ZhengHui QIAN Hui LIANG MiaoLing YANG XiaoChun | 2011 | Science China Earth Sciences2011，54，9： | 62 |
| 2 | The Reference Genome of Tea Plant and Resequencing of 81 Diverse Accessions Provide Insights into Its Genome Evolution and Adaptation显示文摘Tea plant is an important economic crop,which is used to produce the world's oldest and most widely consumed tea beverages.Here,we present a high-quality reference genome assembly of the tea plant(Camellia sinensis var.sinensis)consisting of 15 pseudo-chromosomes.LTR retrotransposons(LTR-RTs)account for 70.38%of the genome,and we present evidence that LTR-RTS play critical roles in genome size expansion and the transcriptional diversification of tea plant genes through preferential insertion in promoter regions and introns.Genes,particularly those coding for terpene biosynthesis pro-teins,associated with tea aroma and stress resistance were significantly amplified through recent tandem duplications and exist as gene clusters in tea plant genome.Phylogenetic analysis of the sequences of 81 tea plant accessions with diverse origins revealed three well-differentiated tea plant populations,support-ing the proposition for the southwest origin of the Chinese cultivated tea plant and its later spread to western Asia through introduction.Domestication and modern breeding left significant signatures on hundreds of genes in the tea plant genome,particularly those associated with tea quality and stress resis-tance.The genomic sequences of the reported reference and resequenced tea plant accessions provide valuable resources for future functional genomics study and molecular breeding of improved cul-tivars of tea plants. | Enhua Xia Wei Tong Yan Hou Yanlin An Linbo Chen Qiong Wu Yunlong Liu Jie Yu Fangdong Li Ruopei Li Penghui Li Huijuan Zhao Ruoheng Ge Jin Huang Ali Inayat Mallano Yanrui Zhang Shengrui Liu Weiwei Deng Chuankui Song Zhaoliang Zhang Jian Zhao Shu Wei Zhengzhu Zhang Tao Xia Chaoling Wei Xiaochun Wan | 2020 | Molecular Plant2020，13，7： | 51 |
| 3 | Discovery of eclogite inclusions and its geological significance in early Jurassic intrusive complex in Xuzhou-northern Anhui, eastern China显示文摘The early Jurassic intrusive complex is chiefly made of monzodioritic porphyry in northern Anhui and northern Jiangsu, which emplaced in 191 Ma. The intrusive complexes contain a lot of eclogite inclusions which belong to eclogite and garnet-pyroxenite. The inclusions had undergone eclogite facies high-pressure metamorphism and am-phibolite facies retrogressive metamorphism. The garnets in eclogite inclusions are mainly almandine varieties and clino-pyroxenes are omphacite and augite. The mineral assemblage and P-T estimation results show that P-T conditions of eclogite facies metamorphism and amphibolite facies retrogressive metamorphism are over 1.2-1.5 GPa, 709-861°C and 0.7-1.03 GPa, 666-738°C, respectively. The discovery of the high-pressure xenoliths not only is of important significance to understand the composition and structure of deep crust in southern edge of North China Platform, but also can be of important influence on realizing the subduc-tion-collision-exhumation evolutional process | Wenliang Xu Dongyan Wang Xiaochun Liu Qinghai Wang Jingqian Lin | 2002 | Chinese Science Bulletin2002，47，14： | 37 |
| 4 | SHRIMP zircon U-Pb dating in Jingshan 'migmatitic granite', Bengbu and its geological significance显示文摘The petrographic characteristics of Jingshan 'migmatitic granite' and the occurrence of the magmatic zircons indicate that the granite was formed by normal crystallization of felsic melts. All zircons in the granite have inherited cores and fine-scale oscillatory zoning rims of magmatic origin. It is realized that the granite was formed at 160.2±1.3 Ma through dating magmatic zircons. The generation of the granitic magma could be related to the lithospheric mantle and/or lower crust delamination after the ultrahigh pressure metamorphism (UHPM) in Triassic. Most inherited zircons yield the ages of 217.1±6.6 Ma, which is consistent with the peak UHPM in the Dabie-Sulu orogenic belt. Some of the inherited zircons (433-722 Ma) constitute a discordia line with the upper intercept age of 850+85/-68 Ma and a lower intercept age of 261+100/-140 Ma. These ages imply that the granite could be derived from the partial melting of the crustal materials of the South China Block that was intensively superimposed by the UHPM. The UHPM could be the reason for the major Pb loss at ±220 Ma. | XU Wenliang, WANG Qinghai, YANG Debin, LIU Xiaochun & GUO Jinghui College of Earth Sciences, Jilin University, Changchun 130061, China Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081, China Institute of Geology & Geophysics, Chinese Academy of Sciences, Beijing 100029, China | 2005 | Science China Earth Sciences2005，48，2： | 32 |
| 5 | Tectonic evolution of the Tongbai-Hong'an orogen in central China: From oceanic subduction/accretion to continent-continent collision显示文摘The Tongbai-Hong'an orogen is located in a key tectonic position linking the Qinling orogen to the west and the Dabie-Sulu orogen to the east. Because the orogen preserves a Paleozoic accretionary orogenic system in the north and a latest PaleozoicMesozoic collisional orogenic system in the south, it may serve as an ideal place to study the tectonic evolution between the North and South China Blocks. The available literature data in the past 20 years indicate that the tectonic processes of the Tongbai-Hong'an orogen involved four stages during the Phanerozoic:(1) Early Paleozoic(490–420 Ma) oceanic subduction, arc magmatism and arc-continent collision created a new Andean-type active continental margin on the North China Block;(2) Late Paleozoic(340–310 Ma) oceanic subduction and accretion generated separated paired metamorphic belts: a medium P/T Wuguan-Guishan complex belt in the south of the Shandan-Songpa fault and a high P/T Xiongdian eclogite belt in the northern edge of the Mesozoic HP metamorphic terrane;(3) Latest Paleozoic-Early Mesozoic(255–200 Ma) continental subduction and collision formed the Tongbai HP terrane in the west and the Hong'an HP/UHP terrane in the east as a consequence of deep subduction towards the east and syn-subduction detachment/exhumation of the down-going slab;(4) Late Mesozoic(140–120 Ma) extension, voluminous magma intrusion and tectonic extrusion led to the final exhumation of the Tongbai-Hong'an-Dabie HP/UHP terrane and the wedge-shaped architecture of the terrane narrowing towards the west. However, many open questions still remain about the details of each evolutionary stage and earlier history of the orogen. Besides an extensive study directly on the Tongbai-Hong'an orogen in the future, integrated investigation on the 'soft-collisional' Qinling orogen in the west and the 'hard-collisional' Dabie-Sulu orogen in the east is required to establish a general tectonic model for the whole Qinling-TongbaiHong'an-Dabie-Sulu orogenic belt. | LIU XiaoChun LI SanZhong JAHN Bor-Ming | 2015 | Science China Earth Sciences2015，58，9： | 34 |
| 6 | The characteristics of atmospheric CO_2 concentration variation of four national background stations in China显示文摘Atmospheric carbon dioxide is an important kind of greenhouse gas which influences global temperature. Its concentration variation could indicate the distribution of human and natural activities in various regions. Through the non-dispersive infrared method, flask sampling of atmospheric CO2 concen- tration was measured weekly at four national background stations including Waliguan, Shangdianzi, Lin’an, and Longfengshan. Based on the data collected from September 2006 to August 2007, along with the Waliguan station’s experience on in situ observational data processing, the selection methods for sampling data through the atmospheric background CO2 concentration analysis were preliminarily discussed. On the basis of this result, the variation features of the four typical regions’ atmospheric background CO2 concentration was analyzed for the first time. The results show that the atmospheric CO2 concentration at Waliguan, Shangdianzi, Lin’an, and Longfengshan is 383.5, 385.9, 387.8, and 384.3 ppm, respectively. During the research period, CO2 concentration at the Waliguan station changed slightly. However, the CO2 concentration changed sharply at the Shangdianzi and the Lin’an stations due to the great influence of human activities in the Jingjinji and the Changjiang Delta economic zones, and changed regularly with seasons at Longfengshan station under dual influences of human activities and plant photosynthesis. The results from this study can lay the foundation for more profound studies on atmospheric CO2 concentration level of different areas in China, and could be used to improve the understanding of carbon source and sink distribution. | LIU LiXin, ZHOU LingXi, ZHANG XiaoChun, WEN Min, ZHANG Fang, YAO Bo & FANG ShuangXi Key Laboratory for Atmospheric Chemistry, Centre for Atmosphere Watch and Services (CAWAS), Chinese Academy of Meteoro- logical Sciences (CAMS), China Meteorological Administration (CMA), Beijing 100081, China | 2009 | Science China Earth Sciences2009，52，11： | 26 |
| 7 | Heavy metal concentrations of agricultural soils and vegetables from Dongguan, Guangdong显示文摘118 农业土壤和 43 件蔬菜样品的一个总数从 Dongguan 城市被收集,广东,中国。空间分发,来源,累积特征和在农业土壤和蔬菜的重金属的潜在的风险被三条不同途径在细节描绘,包括在土壤和蔬菜的八个金属元素的全部的内容,在在学习的土壤的重金属的 GIS 地图和 multivariate 分析。结果证明在农业土壤有象 Cu , Zn , Ni , Pb , Cd 和 Hg 那样的重金属的更高的累积,并且 Pb 的内容( 65.38 mg kg ? 2 )并且 Hg ( 0.24 mg kg ? 2 )分别地是在广东省的土壤的相应重金属的背景内容的 1.82 和 2.82 次。有在附近的 3.4% Cu, 5.9% Ni, 1.7% Cd 和 28% Hg 在所有从有的所有调查地点收集了土壤样品溢出为为土壤标准的中国环境质量的重金属的内容(GB15618-1995,等级 II ) 。在土壤的多金属的污染特征被 Hg 主要反映。到在土壤的八个金属元素有不同来源, Cu, Zn, Ni, Cr 并且这是主要源于父母材料,并且 Pb, Hg 和 Cd 被人为的活动影响。空间分发表演 Cu, Zn, Ni, Cr, Pb 并且农业土壤的 Hg 内容在西方高并且在东方,和 Cd 内容低在西北高,东南并且在在 Dongguan 的西南低。Ni 的蔬菜样品的比率, Pb 并且作为比最大值高的集中,在食物(GB2762-2005 ) 的沾染物的层次分别地是 4.7% , 16.3% 和 48.8% 。在蔬菜的重金属的简历集中因素(BCF ) 的顺序是 Cd > Zn > Cu > 作为 > Ni > Hg > Cr > Pb。在 Dongguan 城市里从农业土壤和蔬菜为食物安全和人健康集中于重金属的潜在的风险是必要的,广东省。 | CAI Limei HUANG Lanchun ZHOU Yongzhang XU Zhencheng PENG Xiaochun YAO Ling'ai ZHOU Yang PENG Ping'an | 2010 | Journal of Geographical Sciences2010，20，1： | 23 |
| 8 | The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease显示文摘Background:Parkinson’s disease(PD)is a chronic,progressive and debilitating disease,which affects over 2.5 million people in China.PD is characterized clinically by resting tremor,muscular rigidity,bradykinesia and postural instability.As the disease progresses,additional complications can arise such as non-motor and neurobehavioral symptoms.Pharmacological treatment and surgical intervention for PD have been implemented in China.Until 10 years ago,there was lack of standardization for the management of PD in different regions and among different physicians,leading to different treatment levels in different regions and different physicians.Since then,the Chinese Parkinson’s Disease and Movement Disorder Society have published three versions of guidelines for the management of PD in China,in 2006,2009 and 2014,respectively.Correspondingly,the overall level of treatment for PD in China improved.Objectives:To update the treatment guidelines based on current foreign and domestic practice guidelines and clinical evidence,and to improve the treatment options available to physicians in the management of PD.Summary:A variety of treatment recommendations in the treatment guidelines have been proposed,including physical activity and disease-modifying medication,which should be initiated at the early-stage of the disease.The principles of dosage titration should be followed to avoid acute adverse reactions to the drugs,to achieve a satisfactory clinical effect with a low dose and to reduce the incidence of long-term motor complications.Moreover,different treatment strategies should be considered at different stages of the disease.Importantly,treatment guidelines and personalized treatments should be valued equally.A set of treatment recommendations has been developed to assist physicians to improve and optimize clinical outcomes for patients with PD in China. | Shengdi Chen Piu Chan Shenggang Sun Haibo Chen Baorong Zhang Weidong Le Chunfeng Liu Guoguang Peng Beisha Tang Lijuan Wang Yan Cheng Ming Shao Zhenguo Liu Zhenfu Wang Xiaochun Chen Mingwei Wang Xinhua Wan Huifang Shang Yiming Liu Pingyi Xu Jian Wang Tao Feng Xianwen Chen Xingyue Hu Anmu Xie Qin Xiao | 2016 | Translational Neurodegeneration2016，5，1： | 23 |
| 9 | Current status and technical challenges of C_(2)storage in coal seams and enhanced coalbed methane recovery:an overview显示文摘In the past two decades,research on C_(2)storage in coal seams and simultaneously enhanced coalbed methane recovery(ECBM)has attracted a lot of attention due to its win–win effect between greenhouse gas(C_(2))emission reduction and coalbed methane recovery enhancement.This paper presents an overview on the current status of research on C_(2)-ECBM in the past two decades,which involves C_(2)storage capacity evaluations,laboratory investigations,modelings and pilot tests.The current status shows that we have made great progress in the ECBM technology study,especially in the understanding of the ECBM mechanisms.However,there still have many technical challenges,such as the definition of unmineable coal seams for C_(2)storage capacity evaluation and storage site characterization,methods for C_(2)injectivity enhancement,etc.The low injectivity of coal seams and injectivity loss with C_(2)injection are the major technique challenges of ECBM.We also search several ways to promote the advancement of ECBM technology in the present stage,such as integrating ECBM with hydraulic fracturing,using a gas mixture instead of pure C_(2)for injection into coal seams and the application of ECBM to underground coal mines. | Xiaochun Li Zhi-ming Fang | 2014 | International Journal of Coal Science & Technology2014，1，1： | 22 |
| 10 | SHRIMP U-Pb zircon dating of the Ordos Basin basement and its tectonic significance显示文摘SHRIMP U-Pb zircon 207 Pb/206 Pb ages were obtained from two drill cores from the basement of the Ordos Basin.A garnet-sillimanite-biotite-plagioclase gneiss(QI1-1) from the western Ordos Basin basement yielded an average age of 2031 10 Ma.Based on the mineral assemblages,the source material of the gneiss is speculated to be pelitic-felsic system.A gneissic two-mica granite(Long1-1) from the eastern Ordos Basin basement yielded an average age of 2035 10 Ma.The zircons from both samples exhibit magmatic growth pattern.The shapes of the zircons suggest that the zircons should crystallize from a granitic of felsic volcanic terrain.The ages and the characters of zircons are consisitent with the other researches in the Ordos Basin and indicate that the basement of the Ordos Basin had experienced an intensive magmatic epsode during the late Paleoproterozoic period.The date from this study suggest the possible existences of a Paleoproterozoic mobile tectonic belt in the region.The reconstruction of such a belt is critical for understanding the tectonomagmatic evolution of the western block of the North China Craton. | HU JianMin LIU XinShe LI ZhenHong ZHAO Yue ZHANG ShuanHong LIU XiaoChun QU HongJie CHEN Hong | 2013 | Chinese Science Bulletin2013，58，1： | 21 |
| 11 | Observation and analysis of near-surface atmospheric aerosol optical properties in urban Beijing显示文摘Year-round measurements of the mass concentration and optical properties of fine aerosols(PM_(2.5)) from June 2009 to May 2010 at an urban site in Beijing were analyzed.The annual mean values of the PM_(2.5) mass concentration,absorption coefficient(Ab),scattering coefficient(Sc) and single scattering albedo(SSA)at 525 nm were 67±66μg/m^3,64 ±62 Mm^(-1),360 ±405 Mm^(-1) and 0.82 ±0.09,respectively.The bulk mass absorption efficiency and scattering efficiency of the PM_(2.5) at 525 nm were 0.78 m^2/g and 5.55 m^2/g,respectively.The Ab and Sc showed a similar diurnal variation with a maximum at night and a minimum in the afternoon,whereas SSA displayed an opposite diurnal pattern.Significant increases in the Ab and Sc were observed in pollution episodes caused by the accumulation of pollutants from both local and regional sources under unfavorable weather conditions.Aerosol loadings in dust events increased by several times in the spring,which had limited effects on the Ab and Sc due to the low absorption and scattering efficiency of dust particles.The frequency of haze days was the highest in autumn because of the high aerosol absorption and scattering under unfavorable weather conditions.The daily PM_(2.5)concentration should be controlled to a level lower than 64 μg/m^3 to prevent the occurrence of haze days according to its exponentially decreased relationship with visibility. | Junshan Jing Yunfei Wu Jun Tao Huizheng Che Xiangao Xia Xiaochun Zhang Peng Yan Deming Zhao Leiming Zhang | 2015 | Particuology2015，13，1： | 16 |
| 12 | The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize显示文摘Maize is a globally important crop that was a classic model plant for genetic studies. Here, we report a 2.2 Gb draft genome sequence of an elite maize line, HuangZaoSi (HZS). Hybrids bred from HZS-improved lines (HILs) are planted in more than 60% of maize fields in China. Proteome clustering of six completed sequeneed maize genomes show that 638 proteins fall into 264 HZS-specific gene families with the majority of contributions from tandem duplication events. Resequencing and comparative analysis of 40 HZSrelated lines reveals the breeding history of HILs. More than 60% of identified selective sweeps were clustered in identity.by.descent conserved regions, and yield-related genes/QTLs were enriched in HZS characteristic selected regions. Furthermore, we dem on strated that HZS-specific family genes were not uniformly distributed in the genome but enriched in improvement/function.related genomic regions. This study provides an important and novel resource for maize genome research and expands our knowledge on the breadth of genomic variation and improvement history of maize. | Chunhui Li Wei Song Yingfeng Luo Shenghan Gao Ruyang Zhang Zi Shi Xiaqing Wang Ronghuan Wang Fengge Wang Jidong Wang Yanxin Zhao Aiguo Su Shuai Wang Xin Li Meijie Luo Shuaishuai Wang Yunxia Zhang Jianrong Ge Xinyu Tan Ye Yuan Xiaochun Bi Hang He Jianbing Yan Yuandong Wang Songnian Hu Jiuran Zhao | 2019 | Molecular Plant2019，12，3： | 15 |
| 13 | miR-129-5p suppresses proliferation, migration, and induces apoptosis in pancreatic cancer cells by targeting PBX3显示文摘Pancreatic cancer(PC)is the seventh m ost frequent cause of cancer-related deaths world wide with a high mortality.MicroRNAs(miRNAs)act as im portant regulators for the developm ent of PC and participate in the progression of PC.miR-129-5p was reported to regulate the progression of tum ors,such as thyroid cancer and gastric cancer.However,the function of miR-129-5p in PC is still unclear.In this study,the down-regulation of miR-129-5p was detected in PC tissues and PC cells.miR-129-5p was overexpressed or knocked down in AsPC-1 and BxPC-3 cells.The results showed that miR-129-5p overexpression suppressed proliferation,m igration and invasion,and induced apoptosis of PC cells,whereas miR-129-5p knockdown showed opposite effects:In addition,we found that pre-B-cell leukemia hom eobox 3(PBX3)overexpression prom oted proliferation,m igration and invasion,but reduced apoptosis of PC cells.PBX3 was identified as a target of miR-129-5p by inform atics analysis and dual luciferase reporter assay.Finally,our results indicated that miR-129-5p suppressed cell proliferation and m igration by targeting PBX3.This study dem onstrated that miR-129-5p could function as a tu m o r suppressor in the progression and developm ent of PC by targeting PBX3,providing a reliable prognostic factor and a new therapeutic strategy for PC. | Zhisheng Qiu Xiaochun Wang Yuping Shi Mingxu Da | 2019 | Acta Biochimica et Biophysica Sinica2019，51，10： | 15 |
| 14 | Quercetin alleviates high glucose-induced Schwann cell damage by autophagy显示文摘Quercetin can reverse high glucose-induced inhibition of neural cell proliferation, and therefore may have a neuroprotective effect in diabetic peripheral neuropathy. It is difficult to obtain primary Schwann cells and RSC96 cells could replace primary Schwann cells in studies of the role of autophagy in the mechanism underlying diabetic peripheral neuropathy. Here, we show that under high glucose conditions, there are fewer autophagosomes in immortalized rat RSC96 cells and primary rat Schwann cells than under control conditions, the proliferative activity of both cell types is significantly impaired, and the expression of Beclin-1 and LC3, the molecular markers for autophagy, is significantly lower. After intervention with quercetin, the autophagic and proliferative activity of both cell types is rescued. These results suggest that quercetin can alleviate high glucose-induced damage to Schwann cells by autophagy. | Ling Qu Xiaochun Liang Bei Gu Wei Liu | 2014 | Neural Regeneration Research2014，9，12： | 14 |
| 15 | Accurate Evaluation of Free-form Surface Profile Error Based on Quasi Particle Swarm Optimization Algorithm and Surface Subdivision显示文摘Although significant progress has been made in precision machining of free-form surfaces recently, inspection of such surfaces remains a difficult problem. In order to solve the problem that no specific standards for the verification of free-form surface profile are available, the profile parameters of free-form surface are proposed by referring to ISO standards regarding form tolerances and considering its complexity and non-rotational symmetry. Non-uniform rational basis spline(NURBS) for describing free-form surface is formulated. Crucial issues in surface inspection and profile error verification are localization between the design coordinate system(DCS) and measurement coordinate system(MCS) for searching the closest points on the design model corresponding to measured points. A quasi particle swarm optimization(QPSO) is proposed to search the transformation parameters to implement localization between DCS and MCS. Surface subdivide method which does the searching in a recursively reduced range of the parameters u and v of the NURBS design model is developed to find the closest points. In order to verify the effectiveness of the proposed methods, the design model is generated by NURBS and the measurement data of simulation example are generated by transforming the design model to arbitrary position and orientation, and the parts are machined based on the design model and are measured on CMM. The profile errors of simulation example and actual parts are calculated by the proposed method. The results verify that the evaluation precision of freeform surface profile error by the proposed method is higher 10%-22% than that by CMM software. The proposed method deals with the hard problem that it has a lower precision in profile error evaluation of free-form surface. | WEN Xiulan ZHAO Yibing WANG Dongxia ZHU Xiaochun XUE Xiaoqiang | 2013 | Chinese Journal of Mechanical Engineering2013，26，2： | 13 |
| 16 | Tomato SlAN11 regulates flavonoid biosynthesis and seed dormancy by interaction with bHLH proteins but not with MYB proteins显示文摘The flavonoid compounds are important secondary metabolites with versatile human nutritive benefits and fulfill a multitude of functions during plant growth and development.The abundance of different flavonoid compounds are finely tuned with species-specific pattern by a ternary MBW complex,which consists of a MYB,a bHLH,and a WD40 protein,but the essential role of SlAN11,which is a WD40 protein,is not fully understood in tomato until now.In this study,a tomato WD40 protein named as SlAN11 was characterized as an effective transcription regulator to promote plant anthocyanin and seed proanthocyanidin(PA)contents,with late flavonoid biosynthetic genes activated in 35S::SlAN11 transgenic lines,while the dihydroflavonol flow to the accumulation of flavonols or their glycosylated derivatives was reduced by repressing the expression of SlFLS in this SlAN11-overexpressed lines.The above changes were reversed in 35S::SlAN11-RNAi transgenic lines except remained levels of flavonol compounds and SlFLS expression.Interestingly,our data revealed that SlAN11 gene could affect seed dormancy by regulating the expressions of abscisic acid(ABA)signaling-related genes SlABI3 and SlABI5,and the sensitivity to ABA treatment in seed germination is conversely changed by SlAN11-overexpressed or-downregulated lines.Yeast two-hybrid assays demonstrated that SlAN11 interacted with bHLH but not with MYB proteins in the ternary MBW complex,whereas bHLH interacted with MYB in tomato.Our results indicated that low level of anthocyanins in tomato fruits,with low expression of bHLH(SlTT8)and MYB(SlANT1 and SlAN2)genes,remain unchanged upon modification of SlAN11 gene alone in the transgenic lines.These results suggest that the tomato WD40 protein SlAN11,coordinating with bHLH and MYB proteins,plays a crucial role in the fine adjustment of the flavonoid biosynthesis and seed dormancy in tomato. | Yongfeng Gao Jikai Liu Yongfu Chen Hai Tang Yang Wang Yongmei He Yongbin Ou Xiaochun Sun Songhu Wang Yinan Yao | 2018 | Horticulture Research2018，5，1： | 13 |
| 17 | Helium Isotope Geochemistry of Ultrahigh-Pressure Metamorphic Eclogites From the Dabie-Sulu Terrane in East China显示文摘The 3He/4He ratios of most eclogites from the Dabie-Sulu terrane range from 0.056 to 0.67 Ra; the data points fall into the mixing part of the crust and the mantle in the 3He-4He diagram. The 3He/4He ratios of eclogites are obviously correlated with the types of their surrounding rocks. The helium isotope composition of the eclogites from the Bixiling complex possesses characters of mantle-derived rocks with the 3He/4He ratio being 5.6 Ra. The 4He concentration of the eclogites exhibits visible inverse correlation with the δ18O value of the quartz in the eclogites from the Sulu area. The δ18O values of the eclogites change synchronously with those of the country rocks. Those results suggest that protoliths of the eclogites were basic-ultrabasic rock bodies or veins intruding into the continental crust in the early stage; strong exchange and hybridization between the basic-ultrabasic rocks and continental rocks and the atmospheric water during the intrusion led to abrupt increase of the 3He/4He ratios, | LI Yanhe LI Jincheng SONG Hebin LIU Xiaochun | 2000 | Acta Geologica Sinica(English Edition)2000，74，1： | 12 |
| 18 | Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12显示文摘Increasing evidences show that aberrant subchondral bone remodeling plays an important role in the development of osteoarthritis(OA).However,how subchondral bone formation is activated and the mechanism by which increased subchondral bone turnover promotes cartilage degeneration during OA remains unclear.Here,we show that the mechanistic target of rapamycin complex 1(mTORC1)pathway is activated in subchondral bone preosteoblasts(Osterix+)from OA patients and mice.Constitutive activation of mTORC1 in preosteoblasts by deletion of the mTORC1 upstream inhibitor,tuberous sclerosis 1,induced aberrant subchondral bone formation,and sclerosis with little-to-no effects on articular cartilage integrity,but accelerated posttraumatic OA development in mice.In contrast,inhibition of mTORC1 in preosteoblasts by disruption of Raptor(mTORC1-specific component)reduced subchondral bone formation and cartilage degeneration,and attenuated post-traumatic OA in mice.Mechanistically,mTORC1 activation promoted preosteoblast expansion and Cxcl12 secretion,which induced subchondral bone remodeling and cartilage degeneration during OA.A Cxcl12-neutralizing antibody reduced cartilage degeneration and alleviated OA in mice.Altogether,these findings demonstrate that mTORC1 activation in subchondral preosteoblasts is not sufficient to induce OA,but can induce aberrant subchondral bone formation and secrete of Cxcl12 to accelerate disease progression following surgical destabilization of the joint.Pharmaceutical inhibition of the pathway presents a promising therapeutic approach for OA treatment. | Chuangxin Lin Liangliang Liu Chun Zeng Zhong-Kai Cui Yuhui Chen Pinling Lai Hong Wang Yan Shao Haiyan Zhang Rongkai Zhang Chang Zhao Hang Fang Daozhang Cai Xiaochun Bai | 2019 | Bone Research2019，7，1： | 12 |
| 19 | Rice Male Development under Drought Stress: Phenotypic Changes and Stage-Dependent Transcriptomic Reprogramming显示文摘干旱影响米饭复制并且导致严重收益损失。在在干旱应力下面的繁殖纸巾的基因规定网络的发展缺点和变化大部分是未知的。在这研究,受到繁殖阶段干旱应力的米饭植物为花的开发和 transcriptomic 变化被检验。结果证明男富饶戏剧性地被影响,与在由于在水应力下面的异常花药开发的一样的圆锥花序的花的不同花粉生存能力。本地淀粉分发的检查表明那淀粉在强调水的植物的花药以位置和丰富反常地积累了。用不同尺寸的小花的 Microarray 分析识别了 > 1000 干旱应答的基因,其大多数明确地在仅仅或小花的二种特别尺寸被调整,建议发展阶段依赖者回答到干旱。知道涉及 tapetum 或小孢子开发,房间墙形成或扩大的基因,和淀粉合成在干旱比染色体一般水准影响的基因之中更经常被发现,当成熟分裂和疯盒子的基因不太经常被影响时。另外,与赤霉素酸发信号有关的小径和 abscisic 酸分解代谢是由干旱的 reprogrammed。我们的结果强烈在强调水的植物建议在繁殖开发,发信号的植物激素,和糖类新陈代谢之间的相互作用。 | Yue Jin Hongxing Yang Zheng Wei Hong Ma Xiaochun Ge | 2013 | Molecular Plant2013，6，5： | 11 |
| 20 | Determination of Forchlorfenuron Dissipation and Residue in Cucumbers and Red Soil显示文摘To assess the risks of forchlorfenuron after application, a residue analysis method for ferchlorfenuron in cucumbers and the red soil of Southern China was established, and the dissipation behavior and residue characteristics of forchlorfenuron were studied under field conditions. The field trials, including dissipation and residue experiments, were conducted in Hunan, Yunnan and Hainan Provinces. Forchlorfenuron was applied at 32 a.i.g ha-1 rate for the dissipation study and both 21 and 32 a.i.g ha-1 for the residue study. Representative cucumbers and soil samples were collected at predetermined intervals for HPLC for UV-detector analysis. The average recoveries of the method were 80.8%-92.0% with coefficients variation (CV) between 0.4% and 11.8%. The detection limit of forchlorfenuron in cucumbers and soil samples was 0.003 mg · kg-1 and the minimum detectable amount was 3.0×10-10 g. The half life of forchlorfenuron in cucumbers in the three provinces changed as: Yunnan (5.50 days), Hunan (5.88 days), and Hainan (6.53 days) and in the soil was observed: Hainan (6.54 days), Hunan (7.64 days), and Yunnan (8.39 days). The maximum terminal residue in cucumbers at 32 a.i.g ha-1 rate after 5 days was 0.009 mg · kg-1 (Yunnan) followed by 0.0085 mg · kg-1 (Hainan) and 0.0082 mg · kg-1 (Hunan) which was below MRL value of 0.01 mg · kg-1 established by the USA, EPA. So a waiting period of 5 days should be established after spaying on cucumbers to avoid hazard to human beings. | LIU Qiang GONG Daoxin PENG Xiaochun YAN Xiaojun | 2010 | Journal of Northeast Agricultural University(English Edition)2010，17，1： | 11 |
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