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| 1 | Advances and challenges in the treatment of esophageal cancer显示文摘Esophageal cancer(EC)is one of the most common cancers with high morbidity and mortality rates.EC includes two histological subtypes,namely esophageal squamous cell carcinoma(ESCC)and esophageal adenocarcinoma(EAC).ESCC primarily occurs in East Asia,whereas EAC occurs in Western countries.The currently available treatment strategies for EC include surgery,chemotherapy,radiation therapy,molecular targeted therapy,and combinations thereof.However,the prognosis remains poor,and the overall five-year survival rate is very low.Therefore,achieving the goal of effective treatment remains challenging.In this review,we discuss the latest developments in chemotherapy and molecular targeted therapy for EC,and comprehensively analyze the application prospects and existing problems of immunotherapy.Collectively,this review aims to provide a better understanding of the currently available drugs through in-depth analysis,promote the development of new therapeutic agents,and eventually improve the treatment outcomes of patients with EC. | Shiming He Jian Xu Xiujun Liu Yongsu Zhen | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 26 |
| 2 | Geochemistry of rare earth elements in the mid-late Quaternary sediments of the western Philippine Sea and their paleoenvironmental significance显示文摘Based on a δ18O chronology,rare earth elements(REE) and other typical elements in sediments from core MD06-3047 in the western Philippine Sea were analyzed to constrain the provenances of the sediments and investigate quantitative changes in the Asian eolian input to the study area over the last 700 ka.Among the competing processes that might affect REE compositions,sediment provenance is the most important one.Provenance analysis suggests that the study sediments have two provenance end-members;local volcanic sources are dominant,and eolian dust from the Asian continent has a smaller contribution.During glacial periods,eolian input to the western Philippine Sea was enhanced.In contrast,material supply from local volcanics increased during interglacial periods.Changes in eolian input to the study area were probably related to the strength of the East Asian winter monsoon(EAWM) as well as aridity in the Asian continent on an orbital time scale,and were partly influenced by local control factors on shorter time scales.Therefore,we propose that the present study expands the application of the REE-based method for quantitatively estimating the eolian component from the mid-latitude northern Pacific to the low-latitude western Pacific.Additionally,the study preliminarily confirms the influence of EAWM-transported eolian material on sedimentation in the western Philippine Sea since 700 ka. | XU ZhaoKai LI TieGang WAN ShiMing YIN XueBo JIANG FuQing SUN HanJie JinYong CHOI DhongIl LIM | 2014 | Science China Earth Sciences2014，57，4： | 10 |
| 3 | High-performance silicon−graphene hybrid plasmonic waveguide photodetectors beyond 1.55μm显示文摘Graphene has attracted much attention for the realization of high-speed photodetection for silicon photonics over a wide wavelength range.However,the reported fast graphene photodetectors mainly operate in the 1.55μm wavelength band.In this work,we propose and realize high-performance waveguide photodetectors based on bolometric/photoconductive effects by introducing an ultrathin wide silicon−graphene hybrid plasmonic waveguide,which enables efficient light absorption in graphene at 1.55μm and beyond.When operating at 2μm,the present photodetector has a responsivity of ~70 mA/W and a setup-limited 3 dB bandwidth of >20 GHz.When operating at 1.55μm,the present photodetector also works very well with a broad 3 dB bandwidth of >40 GHz(setup-limited)and a high responsivity of ~0.4 A/W even with a low bias voltage of−0.3 V.This work paves the way for achieving highresponsivity and high-speed silicon-graphene waveguide photodetection in the near/mid-infrared ranges,which has applications in optical communications,nonlinear photonics,and on-chip sensing. | Jingshu Guo Jiang Li Chaoyue Liu Yanlong Yin Wenhui Wang Zhenhua Ni Zhilei Fu Hui Yu Yang Xu Yaocheng Shi Yungui Ma Shiming Gao Limin Tong Daoxin Dai | 2020 | Light(Science & Applications)2020，9，1： | 10 |
| 4 | Speciation of organic phosphorus in a sediment profile of Lake Taihu I:Chemical forms and their transformation显示文摘Organic phosphorus(nonreactive P,NRP)is a major component of P in sediments,but information about its chemical forms and dynamic transformation is limited.The chemical forms and dynamic behaviors of NRP in a sediment profile from Lake Taihu,a freshwater and eutrophic lake in China,were investigated.Five forms of NRP in the sediments were extracted based on a chemical fractionation technique,including easily labile NRP(NaHCO3-NRP),reactive metal oxide-bound NRP(HCl-NRP),humic acid-associated NRP(NaOH-NRPHA),fulvic acid-associated NRP(NaOH-NRPFA)and residual NRP(Res-TP).There were notable transformations with increasing sediment depth from the labile NaHCO3-NRP and NaOH-NRP pools to the recalcitrant HCl-NRP and Res-TP pools,which caused the NRP to become increasingly recalcitrant as the early diagenetic processes proceeded.Further analyses showed that the relative changes in contents of organic matter and reactive Fe oxides in the sediment profile triggered a competition for binding NRP fractions and led to the transformation of NRP.The results highlighted the importance of abiotic processes in regulating the diagenesis of organic P and its stability in sediments. | Di Xu Shiming Ding Bin Li Xiuling Bai Chengxin Fan Chaosheng Zhang | 2013 | Journal of Environmental Sciences2013，25，4： | 7 |
| 5 | Microstructures and Properties of NiCrBSi/WC Biomimetic Coatings Prepared by Plasma Spray Welding显示文摘 | Shiming Huang Daqian Sun Desheng Xu Wenquan Wang Hongyong Xu | 2015 | Journal of Bionic Engineering2015，12，4： | 7 |
| 6 | Electric conductivity and electric convertibility of potassium acetate in water, ethanol, 2,2,2–trifluoroethanol, 2–propanol and their binary blends显示文摘Salinity gradient energy between the concentrated and diluted electrolyte solutions can be converted to electric energy by using reverse electrodialysis(RED) technology. Electrolyte solution is a vital factor that impacts the energy conversion efficiency. Potassium acetate(KAc) was chosen as solute, and water, ethanol, 2,2,2-trifluoroethanol(TFE), 2-propanol(IPA) and several of their binary mixtures were selected as solvents. Electric conductivity of these solutions were measured under varying conditions. KAc was easily ionized in water and possessed the maximum electric conductivity, following by KAc–H_2O–TFE and KAc–H_2O–ethanol, and then KAc in pure TFE, ethanol, and IPA respectively. For electric convertibility of these solutions working in a RED power generation system, it was found that the KAc–H_2O possessed the maximum power density, and the KAc–ethanol–H_2O possessed the larger open circuit voltage than aqueous KAc solution under the same working condition. Besides, it was observed that both the electric conductivity and electric convertibility were significantly influenced by the concentration and temperature of solution. With the increasing of concentration,electric conductivity of these solutions increased firstly and then reached to the peak, but later it decreased.Solution temperature took a positive impact role to the electric conductivity. Electric conductivity of these solutions can be estimated by using a modified amplitude version of Gaussian peak function. | Xi Wu Shiming Xu Debing Wu Huan Liu | 2018 | Chinese Journal of Chemical Engineering2018，26，12： | 5 |
| 7 | De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation显示文摘Structural variants(SVs) may play important roles in human adaptation to extreme environments such as high altitude but have been under-investigated. Here, combining long-read sequencing with multiple scaffolding techniques, we assembled a high-quality Tibetan genome(ZF1), with a contig N50 length of 24.57 mega-base pairs(Mb) and a scaffold N50 length of 58.80 Mb. The ZF1 assembly filled 80 remaining N-gaps(0.25 Mb in total length) in the reference human genome(GRCh38). Markedly, we detected17 900 SVs, among which the ZF1-specific SVs are enriched in GTPase activity that is required for activation of the hypoxic pathway. Further population analysis uncovered a 163-bp intronic deletion in the MKL1 gene showing large divergence between highland Tibetans and lowland Han Chinese. This deletion is significantly associated with lower systolic pulmonary arterial pressure, one of the key adaptive physiological traits in Tibetans. Moreover, with the use of the high-quality de novo assembly, we observed a much higher rate of genome-wide archaic hominid(Altai Neanderthal and Denisovan) shared non-reference sequences in ZF1(1.32%–1.53%) compared to other East Asian genomes(0.70%–0.98%),reflecting a unique genomic composition of Tibetans. One such archaic hominid shared sequence-a662-bp intronic insertion in the SCUBE2 gene-is enriched and associated with better lung function(the FEV1/FVC ratio) in Tibetans. Collectively, we generated the first high-resolution Tibetan reference genome, and the identified SVs may serve as valuable resources for future evolutionary and medical studies. | Ouzhuluobu Yaoxi He Haiyi Lou Chaoying Cui Lian Deng Yang Gao Wangshan Zheng Yongbo Guo Xiaoji Wang Zhilin Ning Jun Li Bin Li Caijuan Bai Baimakangzhuo Gonggalanzi Dejiquzong Bianba Duojizhuoma Shiming Liu Tianyi Wu Shuhua Xu Xuebin Qi Bing Su | 2020 | National Science Review2020，7，2： | 4 |
| 8 | Investigation of potential interferences on the measurement of dissolved reactive phosphate using zirconium oxide-based DGT technique显示文摘A diffusive gradients in thin films (DGT) technique based on hydrous zirconium oxide (Zr-oxide) has been recently developed for the measurement of dissolved reactive phosphate (DRP). In this study, the detailed performance of the DGT technique is reported. Spiking experiments revealed that several orthophosphate monoester compounds contributed to the Zr-oxide DGT measurements of DRP. However, such a phenomenon is unlikely to occur during field conditions due to the low concentration of organic P in typical natural waters. The presence of Cl- (up to 106 g/L), SO42- (up to 16 g/L), HCO3- (up to 817 g/L), and AsO2- and AsO 3 4 (both up to 1 mg As/L) in solutions had negligible effects on the measurement of DRP. The threshold concentrations of Cl-, SO42- and HCO3- have been increased from previous reports for the measurements of DRP using other adsorbent-based DGT techniques. The capacity for DGT measurements of DRP decreased with increasing solution pH (4.2-9.2). The lowest capacity (95 μg P/m2 at pH 9.2) was still greater than that of other DGT techniques that are usually used for the measurement of DRP (2-12 μg P/cm2 ). The Zr-oxide binding gel could be stored for up to 2 years without any aging effect. This period of validity was considerably longer than the ferrihydrite binding gel that is commonly used in present DGT devices (6 months). The field application revealed that the concentrations of DRP measured in three fresh water samples using the Zr-oxide DGT technique were in agreement with those of the traditional colorimetric method. | Qin Sun Yifei Chen Di Xu Yan Wang Shiming Ding | 2013 | Journal of Environmental Sciences2013，25，8： | 3 |
| 9 | Speciation of organic phosphorus in a sediment profile of Lake Taihu Ⅱ.Molecular species and their depth attenuation显示文摘The understanding of organic phosphorus(P) dynamics in sediments requires information on their species at the molecular level,but such information in sediment profiles is scarce.A sediment profile was selected from a large eutrophic lake,Lake Taihu(China),and organic P species in the sediments were detected using solution phosphorus-31 nuclear magnetic resonance spectroscopy(31 P NMR) following extraction of the sediments with a mixture of 0.25 mol/L NaOH and 50 mmol/L EDTA(NaOH-EDTA) solution.The results showed that P in the NaOH-EDTA extracts was mainly composed of orthophosphate,orthophosphate monoesters,phospholipids,DNA,and pyrophosphate.Concentrations of the major organic P compound groups and pyrophosphate showed a decreasing trend with the increase of depth.Their half-life times varied from 3 to 27 years,following the order of orthophosphate monoesters > phospholipids DNA > pyrophosphate.Principal component analysis revealed that the detected organic P species had binding phases similar to those of humic acid-associated organic P(NaOH-NRP HA),a labile organic P pool that tends to transform to recalcitrant organic P pools as the early diagenetic processes proceed.This demonstrated that the depth attenuation of the organic P species could be partly attributed to their increasing immobilization by the sediment solids,while their degradation rates should be significantly lower than what were suggested in previous studies. | Shiming Ding Di Xu Xiuling Bai Shuchun Yao Chengxin Fan Chaosheng Zhang | 2013 | Journal of Environmental Sciences2013，25，5： | 3 |
| 10 | Evaluation of Snow Depth and Snow Cover Fraction Simulated by Two Versions of the Flexible Global Ocean–Atmosphere–Land System Model显示文摘Based on historical runs, one of the core experiments of the fifth phase of the Coupled Model Intercomparison Project(CMIP5), the snow depth(SD) and snow cover fraction(SCF) simulated by two versions of the Flexible Global Ocean– Atmosphere–Land System(FGOALS) model, Grid-point Version 2(g2) and Spectral Version 2(s2), were validated against observational data. The results revealed that the spatial pattern of SD and SCF over the Northern Hemisphere(NH) are simulated well by both models, except over the Tibetan Plateau, with the average spatial correlation coefficient over all months being around 0.7 and 0.8 for SD and SCF, respectively. Although the onset of snow accumulation is captured well by the two models in terms of the annual cycle of SD and SCF, g2 overestimates SD/SCF over most mid- and high-latitude areas of the NH. Analysis showed that g2 produces lower temperatures than s2 because it considers the indirect effects of aerosols in its atmospheric component, which is the primary driver for the SD/SCF difference between the two models. In addition, both models simulate the significant decreasing trend of SCF well over(30°–70°N) in winter during the period 1971–94. However, as g2 has a weak response to an increase in the concentration of CO2and lower climate sensitivity, it presents weaker interannual variation compared to s2. | XIA Kun WANG Bin LI Lijuan SHEN Si HUANG Wenyu XU Shiming DONG Li LIU Li | 2014 | Advances in Atmospheric Sciences2014，31，2： | 3 |
| 11 | Viscosity and degradation controlled injectable hydrogel for esophageal endoscopic submucosal dissection显示文摘Endoscopic submucosal dissection(ESD)is a common procedure to treat early and precancerous gastrointestinal lesions.Via submucosal injection,a liquid cushion is created to lift and separate the lesion and malignant part from the muscular layer where the formed indispensable space is convenient for endoscopic incision.Saline is a most common submucosal injection liquid,but the formed liquid pad lasts only a short time,and thus repeated injections increase the potential risk of adverse events.Hydrogels with high osmotic pressure and high viscosity are used as an alternate;however,with some drawbacks such as tissue damage,excessive injection resistance,and high cost.Here,we reported a nature derived hydrogel of gelatin-oxidized alginate(G-OALG).Based on the rheological analysis and compare to commercial endoscopic mucosal resection(EMR)solution(0.25%hyaluronic acid,HA),a designed G-OALG hydrogel of desired concentration and composition showed higher performances in controllable gelation and injectability,higher viscosity and more stable structures.The G-OALG gel also showed lower propulsion resistance than 0.25%HA in the injection force assessment under standard endoscopic instruments,which eased the surgical operation.In addition,the G-OALG hydrogel showed good in vivo degradability biocompatibility.By comparing the results acquired via ESD to normal saline,the G-OALG shows great histocompatibility and excellent endoscopic injectability,and enables create a longer-lasting submucosal cushion.All the features have been confirmed in the living both pig and rat models.The G-OALG could be a promising submucosal injection agent for esophageal ESD. | Chaoqiang Fan Kaige Xu Yu Huang Shuang Liu Tongchuan Wang Wei Wang Weichao Hu Lu Liu Malcolm Xing Shiming Yang | 2021 | Bioactive Materials2021，6，4： | 3 |
| 12 | Updating preconditioner for iterative method in time domain simulation of power systems显示文摘The numerical solution of the differential-algebraic equations(DAEs) involved in time domain simulation(TDS) of power systems requires the solution of a sequence of large scale and sparse linear systems.The use of iterative methods such as the Krylov subspace method is imperative for the solution of these large and sparse linear systems.The motivation of the present work is to develop a new algorithm to efficiently precondition the whole sequence of linear systems involved in TDS.As an improvement of dishonest preconditioner(DP) strategy,updating preconditioner strategy(UP) is introduced to the field of TDS for the first time.The idea of updating preconditioner strategy is based on the fact that the matrices in sequence of the linearized systems are continuous and there is only a slight difference between two consecutive matrices.In order to make the linear system sequence in TDS suitable for UP strategy,a matrix transformation is applied to form a new linear sequence with a good shape for preconditioner updating.The algorithm proposed in this paper has been tested with 4 cases from real-life power systems in China.Results show that the proposed UP algorithm efficiently preconditions the sequence of linear systems and reduces 9%-61% the iteration count of the GMRES when compared with the DP method in all test cases.Numerical experiments also show the effectiveness of UP when combined with simple preconditioner reconstruction strategies. | WANG Ke XUE Wei LIN HaiXiang XU ShiMing ZHENG WeiMin | 2011 | Science China(Technological Sciences)2011，54，4： | 3 |
| 13 | Characteristics of sedimentation and channel adjustment linked to the Three Gorges Reservoir显示文摘Construction of large dams is attractive because of their great benefits in flood control,hydropower generation,water resources utilization,navigation improvement,etc.However,dam construction may bring some negative impacts on sediment transport and channel dynamics adjustments.Due to the effects of recent water and soil conservation projects,sediment retention in the newly constructed large upstream reservoirs,and other factors,the sedimentation in the Three Gorges Reservoir(TGR)is quite different from the amount previously predicted in the demonstration stage.Consequently,based on the measured data,characteristics of sedimentation and the related channel deformation in the TGR were analyzed.The results imply that sediment transport tended to be reduced after the Three Gorges Project(TGP).Sedimentation slowed dramatically after 2013 and indicated obvious seasonal characteristics.Due to the rising water level in the TGR in the flood season,the yearly sediment export ratio(Eratio)was prone to decrease.The water level near the dam site should be reasonably regulated according to the flow discharge to improve the sediment delivery capacity and reduce sedimentation in the TGR,and to try to avoid situations where the flood retention time is close to 444 h.The depositional belt was discontinuous in the TGR and was mainly distributed in the broad reaches,and only slight erosion or deposition occurred in the gorge reaches.Sedimentation in the broad and gorge reaches accounted for 93.8% and 6.2% of the total sedimentation,respectively.The estuarine reach located in the fluctuating backwater area experienced alternate erosion-deposition,with a slight accumulative deposition in the curved reach.Sedimentation mainly occurred in the perennial backwater area.The insight gained in this study can be conducive to directly understanding of large reservoir sedimentation and mechanism of channel adjustment in the reservoir region in the main channel of large river. | Xiaoya Tang Sichen Tong Guoxian Huang Guangxiang Xu Xinghua Li Kun Lei Shiming Yao | 2021 | International Journal of Sediment Research2021，36，2： | 3 |
| 14 | Cloning of the key genes in maize oxylipins pathways and their roles in herbivore induced defense显示文摘To gain an understanding of the molecular ba-sis of signaling pathways in herbivore-induced maize plant defense, three key genes, ZmAOS, ZmAOC and ZmHPL, which are involved in the biosynthesis of oxylipin signals, have been cloned using RT-PCR in this study. Beet army-worm (BAW) infestation induced the systemic expression of the key genes involved in the biosynthesis of oxylipin signals similar to exogenous methyl jasmonate (MeJA). Moreover, the systemic expression patterns of maize defense-related genes were similar between maize leaves induced by jas-monic acid (JA) and damaged by BAW. Previous treatment with salicyhydroxamic acid (SHAM), an inhibitor of jas-monates (JAs) signal pathway followed by BAW infestation did not induce the systemic expression of the defense-related genes. Exposure to the vapors of green leafy volatiles (GLVs, (Z)-3-hexen-1-ol, (E)-2-hexenal, (E)-3-hexenal) and β-oci- mene induced the expression of the defense-related genes, as well as the key genes involved in biosynthesis of JAs. How-ever, previous treatment with SHAM clearly decreased the transcript levels of the defense genes induced by (Z)-3-hexen-1-ol, (E)-2-hexenal and (E)-3- hexenal. These results demonstrate the major role of oxylipin signal path-way in herbivore-induced maize chemical defense. JA was the endogenous signal in the process of herbivore-induced maize systemic defense. GLVs, another group of oxylipin, played an important role in the process of herbivore-induced systemic defense outside the plant. Furthermore, the expres-sion of defense-related genes induced by GLVs was partially dependent on JAs signal pathway, while β-ocimene induction was independent of JAs signal pathway. | XU Tao WANG Jianwu LUO Shiming | 2005 | Chinese Science Bulletin2005，50，21： | 2 |
| 15 | Co_(78)Si_(8)B_(14)metallic glass:A highly efficient and ultra-sustainable Fenton-like catalyst in degrading wastewater under universal pH conditions显示文摘Overcoming the pH limitation and increasing the catalyst reusability remain pressing demands for metal-lic glass(MG)in wastewater remediation.Herein,Co_(78)Si_(8)B_(14)MG ribbons are used to degrade dye wastew-ater by activating hydrogen peroxide(H_(2)O_(2))as Fenton-like catalysts.The Co-based MG catalysts exhibit high degradation efficiency under both acidic and alkaline conditions,and the kinetic reaction rate at pH 10(0.176 min^(−1)) and pH 4(0.089 min^(−1)) is 5.9 and 1.2 times higher than that of the extensively studied Fe-based MG catalysts,respectively.Impressively,the Co-based MG catalysts can be reused up to 20-60 times at universal pH conditions,demonstrating fairly good reusability.The newly discovered Co-based MG catalysts do not follow the classical Fenton reactions with H_(2)O^(2) the way Fe-based MGs do.In an acid environment,hydroxyl radicals play a dominant role in the degradation,while in an alkaline environ-ment,the effect of hydroxyl radicals is weakened,and Co^(3+) ions exert a relatively major function on the degradation.The excellent performance in catalytic activity and reusability at universal pH conditions of the Co-based MGs will inspire the development of MGs in wastewater treatment. | Xindong Qin Jiliang Xu Zhengwang Zhu Zhengkun Li Dawei Fang Huameng Fu Shiming Zhang Haifeng Zhang | 2022 | Journal of Materials Science & Technology2022，，18： | 2 |
| 16 | LOWER DOSE OF AMINOGLYCOSIDE OTOTOXIC EXPOSURE CAUSES PRESYNAPTIC ALTERATIONS ASSOICATED WITH HEARING LOSS显示文摘Objective To study presynaptic alternations of cochlear ribbons arising from aminoglycoside ototoxic stimuli in C57BL/6J mice. Methods Animals were injected with low dose gentamicin(100 mg/kg/day) for14 days, From the 14 th to 28 th days, the mice were maintained free of gentamicin treatment. Immunohistochemistry labeling was employed to trace RIBEYE, a major presynaptic componment of ribbon synapses.RIBEYE/CtBP2 expression levels were assessed and compared with hearing threshold shifts. Auditory function was assessed by auditory brainstem responses. The stereocilia of outer hair cells(OHCs) and IHCs was examined by scanning electron microscopy(SEM). Results Hearing thresholds were elevated with peak hearing loss observed on the 7th day after gentamicin exposure, followed by improvement after the 7th day.RIBEYE/CtBP2 expression directly correlated with observed hearing threshold shifts. Strikingly, we did not see any obvious changes in stereocilia in both OHCs and IHCs until the 28 th day. Mild changes in stereocilia were only observed in OHCs on the 28 th day. Conclusions These findings indicate that presynapse cochlear ribbons, rather than stereocilia, may be sensitive to aminoglycoside ototoxic exposure in mice cochleae. A pattern of RIBEYE/CtBP2 expression changes seems to parallel hearing threshold shifts and suggests presynaptic response properties to lower dosage of aminoglycoside ototoxic stimuli. | LIU Ke WANG Xiaoyu LI Sijun TANG Siquan XU Yice WANG Xuefeng SUN Jianhe YANG Weiyan YANG Shiming | 2014 | Journal of Otology2014，9，1： | 2 |
| 17 | Nitrogen addition and mowing alter drought resistance and recovery of grassland communities显示文摘Nitrogen enrichment and land use are known to influence various ecosystems,but how these anthropogenic changes influence community and ecosystem responses to disturbance remains poorly understood.Here we investigated the effects of increased nitrogen input and mowing on the resistance and recovery of temperate semiarid grassland experiencing a three-year drought.Nitrogen addition increased grassland biomass recovery but decreased structural recovery after drought,whereas annual mowing increased grassland biomass recovery and structural recovery but reduced structural resistance to drought.The treatment effects on community biomass/structural resistance and recovery were largely modulated by the stability of the dominant species and asynchronous dynamics among species,and the community biomass resistance and recovery were also greatly driven by the stability of grasses.Community biomass resistance/recovery in response to drought was positively associated with its corresponding structural stability.Our study provides important experimental evidence that both nitrogen addition and mowing could substantially change grassland stability in both functional and structural aspects.Our findings emphasize the need to study changes across levels of ecological organization for a more complete understanding of ecosystem responses to disturbances under widespread environmental changes. | Zhuwen Xu Heyong Liu Yani Meng Jinfei Yin Haiyan Ren Mai-He Li Shan Yang Shiming Tang Yong Jiang Lin Jiang | 2023 | Science China(Life Sciences)2023，66，7： | 2 |
| 18 | Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells显示文摘 | Hui Yang Yun Zhong Hui Xie XiaoBo Lai Miqing Xu Yuqiang Nie Shiming Liu Yu-Jui Yvonne Wan | 2013 | Biochemical Pharmacology2013，，12： | 2 |
| 19 | A simula- tion study on the operating performance of a solar-air source heat pump water heater显示文摘 | Xu Guoying Zhang Xiaosong Deng Shiming | 2006 | Applied Thermal En- gineering2006，26，： | 1 |
| 20 | Evaluation of in situ capping with clean soils to control phosphate release from sediments显示文摘 | XU Di DING Shiming SUN Qin | 2012 | Sci Total Environ2012，438，： | 1 |
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