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| 1 | Friction of low-dimensional nanomaterial systems显示文摘When material dimensions are reduced to the nanoscale,exceptional physical mechanics properties can be obtained that differ significantly from the corresponding bulk materials.Here we review the physical mechanics of the friction of low‐dimensional nanomaterials,including zero‐dimensional nanoparticles,one‐dimensional multiwalled nanotubes and nanowires,and two‐dimensional nanomaterials-such as graphene,hexagonal boron nitride(h‐BN),and transition‐metal dichalcogenides-as well as topological insulators.Nanoparticles between solid surfaces can serve as rolling and sliding lubrication,while the interlayer friction of multiwalled nanotubes can be ultralow or significantly high and sensitive to interwall spacing and chirality matching,as well as the tube materials.The interwall friction can be several orders of magnitude higher in binary polarized h‐BN tubes than in carbon nanotubes mainly because of wall buckling.Furthermore,current extensive studies on two‐dimensional nanomaterials are comprehensively reviewed herein.In contrast to their bulk materials that serve as traditional dry lubricants(e.g.,graphite,bulk h‐BN,and MoS_(2)),large‐area high‐quality monolayered two‐dimensional nanomaterials can serve as single‐atom‐thick coatings that minimize friction and wear.In addition,by appropriately tuning the surface properties,these materials have shown great promise for creating energy‐efficient self‐powered electro‐opto‐magneto‐mechanical nanosystems.State‐of‐the‐art experimental and theoretical methods to characterize friction in nanomaterials are also introduced. | Wanlin GUO Jun YIN Hu QIU Yufeng GUO Hongrong WU Minmin XUE | 2014 | Friction2014，2，3： | 15 |
| 2 | Epigenetics in the pathogenesis of diabetic nephropathy显示文摘Diabetic nephropathy(DN),which is a common microvascular complication with a high incidence in diabetic patients,greatly increases the mortality of patients.With further study on DN,it is found that epigenetics plays a crucial role in the pathophysiological process of DN.Epigenetics has an important impact on the development of DN through a variety of mechanisms,and promotes the generation and maintenance of metabolic memory,thus ultimately leading to a poor prognosis.In this review we discuss the methylation of DNA,modification of histone,and regulation of non-coding RNA involved in the progress of cell dysfunction,inflammation and fibrosis in the kidney,which ultimately lead to the deterioration of DN. | Xue Li Lihong Lu Wenting Hou Ting Huang Xiangyuan Chen Jie Qi Yanjun Zhao Minmin Zhu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，2： | 6 |
| 3 | Aberrant activation of Sonic hedgehog signaling in chronic cholecystitis and gallbladder carcinoma显示文摘 | Fang Xie Xiaoping Xu Angao Xu Cuiping Liu Fenfen Liang Minmin Xue Lan Bai | 2013 | Human Pathology2013，，： | 1 |
| 4 | Preparation and application of nanoscale microemulsion as binder for fabric inkjet printing显示文摘 | XUE Chaohua SHI Minmin CHEN Hongzheng | 2006 | Colloids and Surfaces A:Physicochem Eng Aspects2006，287，： | 1 |
| 5 | Water models for interfacial water simulations显示文摘Interfacial water is of fundamental importance in many technological fields, such as biological processes, chemical reactions and lubrications. A prevalent way to study the structure and dynamics of interfacial water is carrying out molecular dynamics simulations with empirical potential water models. However, discrepant results have been reported due to their different charge geometries and target properties. Here we investigated the interfacial water structures on smooth surfaces of varying hydrophobicity at low temperatures by comprehensive molecular dynamics simulations with the prevailing water models. It is shown that the choice of the water model can significantly change the water structure on the hydrophilic surface, while has a minor effect on the contact angle on a hydrophobic surface. Furthermore, zero-dimensional ice pyramids and one-dimensional icicles were formed under the regulation of external charges injected to the substrate or imposed electric field, respectively. These results offer new insights into the water structures on different surfaces and reasonable choice of parameters in molecular simulations, and the development of water models. | XUE MinMin GUO WanLin | 2019 | Science China(Technological Sciences)2019，62，5： | 1 |
| 6 | Functionalizations of boron nitride nanostructures显示文摘Boron nitride(BN) nanomaterials share the same atomic structures as their carbon counterparts, with mechanical and thermal properties second only to carbon counterparts. Especially, the iconicity of B-N bonds results in exceptionally high thermal stability and corrosion resistance, making BN nanomaterials a compelling contender for fabricating devices that can operate under harsh environments. However, all pristine BN nanomaterials are electric insulators and lack semiconductive functionality.How to efficiently regulate the electronic properties of BN nanomaterials has impeded the way of delivering their potential into applications. Here, we report an overview of key progress in functionalizing BN nanostructures by means of multi-physical-field coupling at nanoscale. In particular, we present how the chemical doping, electric fields, elastic strains and interfaces can modify the band structures and hence lead to narrowed bandgap and even magnetism in various BN nanostructures. We also discuss the effect of these modulation methods on charge carrier motility as well as potential challenges of their experimental implementation. Without applied doping, strain and electric field, employing inherent BN polarity to form electrically polarized interfaces is proposed to functionalize BN nanostructures towards controlled electronic properties combined with high carrier motility. We finally discuss recent progress of experimental synthesis of quality h-BN samples in large area. | BAI YaLei XUE MinMin ZHAO ZhiQiang ZHANG ZhuHua | 2021 | Science China(Technological Sciences)2021，64，1： | 1 |
| 7 | China·Zhangzhou Cross-Strait Viewing Stone Appreciation Cultural Exchange Exhibition Held A Grand Opening Ceremony显示文摘The flourishing age of China,the great beauty of Zhangzhou.Across the Taiwan Strait and Chinese mainland,we share the joy,Jiu Longbi stone add its splendor.On May 16,2019,China.Zhangzhou Cross-Strait Viewing Stone Appreciation Cultural Exchange Exhibition held a grand opening ceremony at Zhangzhou Museum of Art,Fujian Province. | Sun Yongfeng Xue Minmin | 2019 | 宝藏2019，，6： | 0 |
| 8 | Graphene binding on black phosphorus enables high on/off ratios and mobility显示文摘Graphene is one of the most promising candidates for integrated circuits due to its robustness against short-channel effects,inherent high carrier mobility and desired gapless nature for Ohmic contact,but it is difficult to achieve satisfactory on/off ratios even at the expense of its carrier mobility,limiting its device applications.Here,we present a strategy to realize high back-gate switching ratios in a graphene monolayer with well-maintained high mobility by forming a vertical heterostructure with a black phosphorus multi-layer.By local current annealing,strain is introduced within an established area of the graphene,which forms a reflective interface with the rest of the strain-free area and thus generates a robust off-state via local current depletion.Applying a positive back-gate voltage to the heterostructure can keep the black phosphorus insulating,while a negative back-gate voltage changes the black phosphorus to be conductive because of hole accumulation.Then,a parallel channel is activated within the strain-free graphene area by edge-contacted electrodes,thereby largely inheriting the intrinsic carrier mobility of graphene in the on-state.As a result,the device can provide an on/off voltage ratio of>10^(3)as well as a mobility of∼8000 cm^(2)V^(−1)s^(−1)at room temperature,meeting the low-power criterion suggested by the International Roadmap for Devices and Systems. | Fanrong Lin Zhonghan Cao Feiping Xiao Jiawei Liu Jiabin Qiao Minmin Xue Zhili Hu Ying Liu Huan Lu Zhuhua Zhang Jens Martin Qingjun Tong Wanlin Guo Yanpeng Liu | 2024 | National Science Review2024，11，2： | 0 |
| 9 | 缰核相关神经通路可介导光疗的抗抑郁作用显示文摘文章简介视网膜所感知的光信息可调节抑郁情绪在内的多种非成像功能。虽然临床研究表明光疗可显著改善抑郁症状,但光疗抗抑郁作用产生的神经通路机制尚不明确。在本研究中,研究人员通过采用神经环路示踪技术发现在小鼠中存有一条连接视网膜(Retina)与外侧缰核(LHb)的跨双突触神经通路。 | 黄鲁 席月 黄晓丹 Yan Yang Xiaodan Huang Yunwei Fu Qian Tao Jia Xiao Tifei Yuan Kai An Huan Zhao Mingliang Pu Fuqiang Xu Tian Xue Minmin Luo Kwok-Fai So 任超然 苏国辉 | 2020 | 科学新闻2020，，2： | 0 |
| 10 | Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer显示文摘Chemoresistance remains a major obstacle to successful treatment of triple negative breast cancer(TNBC).Identification of druggable vulnerabilities is an important aim for TNBC therapy.Here,we report that SERCA2 expression correlates with TNBC progression in human patients,which promotes TNBC cell proliferation,migration and chemoresistance.Mechanistically,SERCA2 interacts with LC3B via LIR motif,facilitating WIPI2-independent autophagosome formation to induce autophagy.Autophagy-mediated SERCA2 degradation induces SERCA2 transactivation through a Ca^(2+)/CaMKK/CREB-1 feedback.Moreover,we found that SERCA2-targeting small molecule RL71 enhances SERCA2-LC3B interaction and induces excessive autophagic cell death.The increase in SERCA2 expression predisposes TNBC cells to RL71-induced autophagic cell death in vitro and in vivo.This study elucidates a mechanism by which TNBC cells maintain their high autophagy activity to induce chemoresistance,and suggests increased SERCA2 expression as a druggable vulnerability for TNBC. | Minmin Fan Jian Gao Lin Zhou Wenwen Xue Yixuan Wang Jingwei Chen Wuhao Li Ying Yu Bo Liu Yan Shen Qiang Xu | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 0 |
| 11 | An analog of Friedel oscillations in nanoconfined water显示文摘Water confined in nanometer-scale crevices and cavities underpins a wide range of fundamental processes,such as capillary flow,ion transport and protein folding.However,how water responds within these confined spaces,with prevalent inhomogeneity built in or caused by impurities,is not well understood.Here,we show theoretically that water confined in one-dimensional nano channels with localized perturbation exhibits pronounced density oscillations.The oscillations occur vividly like the Friedel oscillations in electron density resulting from defects in metals.A model analysis reveals that the density oscillations result from the perturbation-induced molecular scattering that is augmented by the confinement-enhanced correlation of water dipoles.This renders the oscillations a general behavior independent of the channel geometries and specific forms of the perturbation.Under confinements comparable to biological ion channels,such oscillations can strikingly extend over 10 nm,resulting in non-trivial effects at large distances that,for example,repel all ions from the channels with their long-range force.These results deepen the understanding of biological functions and inspire new applications in a variety of domains,such as ionic sensing and seawater desalination. | Minmin Xue Zhili Hu Hu Qiu Chun Shen Wanlin Guo Zhuhua Zhang | 2022 | National Science Review2022，9，9： | 0 |
| 12 | Genetic analysis and QTL mapping of growth period traits and plant height traits in soybean recombinant inbred lines from Dongnong 47 × PI 317334-B显示文摘High and stable yield is the main goal of soybean genetic improvement.In this study,association analysis was used to detect the quantitative trait loci(QTL)for the plant height,and soybean growth period using 182 SSR markers in the RIL population of 136 F_(4:8) lines,which developed from a cross between photoperiod-insensitive cultivar‘Dongnong 47’and photoperiod-sensitive variety PI317334–B.The results showed that 33 QTLs related to soybean growth period and plant height traits were detected by compound interval mapping,and were located on 12 linkage groups including N,C1,C2,J,D1a,B2,E,G,A2,O,L,I,with the contribution rate of 7.85–33.84%.These QTL loci and linkage markers related to soybean photoperiod sensitivity,would be helpful to identify key genes that control soybean photoperiod sensitivity,and provide an important basis for the breeding of new photoperiod-insensitive soybean varieties based on molecular design breeding. | Jing Li Jiafan Sun Minmin Li Xue Zhao Lin Zhao | 2021 | Oil Crop Science2021，6，2： | 0 |
| 13 | Remarkable difference of phospholipid molecular chirality in regulating PrP aggregation and cell responses显示文摘Prion diseases are fatal neurodegenerative diseases that can cause severe dementia.The misfolding and accumulation of the prion peptide (PrP)_(106–126) is crucial,and this process is closely relevant to biological membranes.However,how PrP_(106–126)aggregation is affected by the molecular chirality of phospholipid membrane is unknown.Thus,in this study,a pair of L-and D-aspartic acid (Asp)-modified 1,2-dipalmitoyl-sn–glycero-3-phosphoethanolamine (DPPE) were synthesized to construct chiral liposomes.We discover that L-Asp-DPPE liposomes strongly inhibit the oligomerization and amyloidogenesis of PrP_(106–126),whether acting on monomers or oligomers,which rescues cytotoxicity induced by PrP_(106–126).By comparison,D-Asp-DPPE liposomes inhibit peptide oligomerization only at a high concentration and cannot prevent amyloidogenesis when acting on oligomers,which lead to pronounced cytotoxicity.Apoptosis experiment,dynamic change of intracellular Ca^(2+)(_(i)Ca^(2+)) and Ca^(2+)release from endoplasmic reticulum(ER),reactive oxygen species (ROS) production,adsorption dynamics and affinity tests,and fluorescent imaging clearly disclose that molecular chirality of the liposomes dominates conformational transition of PrP_(106–126)from random coil to β-sheet,binding and adsorption of the monomers and oligomers,and subsequent fibrillation process,resulting in distinct inhibition effect in Ca^(2+)overload and release,ROS production and cell apoptosis.This work is the first to report that interfacial molecular chirality is a potentially crucial influence on the fibrillation process of PrP_(106–126) and its cell responses,whereas the convergence of chiral amino acids and liposomes can be considered potential inhibitors in prion diseases. | Cunli Wang Xue Wang Dongdong Wang Shengxu Qian Fusheng Zhang Mingyang Li Minmin Li Wenqi Lu Bo Liu Guangyan Qing | 2023 | Chinese Chemical Letters2023，34，2： | 0 |
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