|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Identification of sex phero-mones of four economically important species in genus Dendrolimus显示文摘The female-produced sex pheromone of Den-drolimus superans was identified by gas chromatography (GC), coupled GC-mass spectrometry (GC-MS), electroan-tennographic (EAG) studies and field tests as a blend of (Z,E)-5,7-dodecadienal (Z5,E7-12:Ald) and (Z,E)-5,7-dodeca-dien-1-ol (Z5,E7-12:OH). In D. kikuchii, (Z,E)-5,7-dodeca-dien-1-yl acetate (Z5,E7-12:OAc) and Z5,E7-12:OH were found by GC and GC-MS analyses. However, in EAG studies male antennae were more sensitive to Z5,E7-12:OAc and (Z,E)-5,7-dodecadien-l-yl propionate (Z5,E7-12:OPr) than Z5,E7-12:OH. For D. spectabilis, Z5,E7-12:OH had been previously reported as the sex pheromone. However, in our studies, traps baited with Z5,E7-12:OH, Z5,E7-12:OAc and Z5,E7-12:OPr in a ratio of 1:1:1 caught three times more males than those baited with Z5,E7-12:OH alone. Relatively strong EAG responses were elicited from male antennae by Z5,E7-12:OH, Z5,E7-12:OAc and Z5,E7-12:OPr, but in addition to Z5,E7-12:OH, only very small amounts of Z5,E7-12:OAc was found in | Kong Xiangbo Zhao Chenghua Gao Wei | 2001 | Chinese Science Bulletin2001，46，24： | 12 |
| 2 | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332显示文摘Dear Editor,Since December 2019,the pandemic of coronavirus disease 2019(COVID-19)has taken a heavy toll on global health,creating an urgent need to develop effective strategies for prevention and treatment.The etiological agent,known as severe acute respiratory syndrome coronavirus 2(SARSCoV-2),has infected nearly 229.2 million people worldwide with more than 4.7 million deaths as of September 15,2021.Older age and preexisting health conditions are associated with worse clinical prognosis including higher mortality rates(Zhou et al.,2020).The global race to combat this pandemic has led to rapid deployment of numerous effective vaccines against SARS-CoV-2(Tregoning et al.,2021).However,the emergence of viral variants,including the Delta variant(B.1.617.2),compromised vaccine effectiveness with resurgence of SARS-CoV-2 infection among highly vaccinated population(Keehner et al.,2021).Therefore,development of therapeutics against the more conserved viral targets would be essential to contain the spread of COVID-19 and reduce mortality. | Yao Zhao Chao Fang Qi Zhang Ruxue Zhang Xiangbo Zhao Yinkai Duan Haofeng Wang Yan Zhu Lu Feng Jinyi Zhao Maolin Shao Xiuna Yang Leike Zhang Chao Peng Kailin Yang Dawei Ma Zihe Rao Haitao Yang | 2022 | Protein & Cell2022，13，9： | 6 |
| 3 | OS1 functions in the allocation of nutrients between the endosperm and embryo in maize seeds显示文摘Uncovering the genetic basis of seed develop-ment will provide useful tools for improving both crop yield and nutritional value, However, the genetic regulatory networks of maize (Zea mays) seed development remain largely unknown. The maize opaque endosperm and small germ 1 (osl) mutant has opaque endosperm and a small embryo,Here, we cloned OSi1 and show that it encodes a putative transcription factor containing an RWP-RK domain-Transcriptional analysis indicated that OSi1 expression is elevated in early endosperm development, especially in the basal endosperm transfer layer (BETL), conducting zone (CZ), and central starch endospcrm (CSE) cells. RNA sequencing (RNA-Seq) analysis of the osi mutant revealed sharp downregulation of certain genes in specific cell types, including ZmMRP-1 and Megl in BETL cells and a majority of zein-and starch-related genes in CSE cells. Using a haploid induction system, we show that wild-type endosperm could rescue the smaller size of osi embryo, which suggests that nutrients are allocated by tho wild type endosperm. Therefore, our dsta imply that the network regulated by 051 accomplishes a key step in nutrient allocation between endosperm and embryo within maize seeds. Identification of this network will help uncover the mechanisms regulating the nutritional balance between endosperm and embryo. | Weibin Song Jinjie Zhu Haiming Zhao Yingnan Li Jiangtao Liu Xiangbo Zhang Liangliang Huang Jinsheng Lai | 2019 | Journal of Integrative Plant Biology2019，61，6： | 3 |
| 4 | The effect of tourniquet use on hidden blood loss in total knee arthroplasty显示文摘 | Bin Li Yu Wen Haishan Wu Qirong Qian Xiangbo Lin Hui Zhao | 2009 | International Orthopaedics2009，，5： | 1 |
| 5 | MP3RNA-seq:Massively parallel 3’end RNA sequencing for high-throughput gene expression profiling and genotyping显示文摘Transcriptome deep sequencing(RNA‐seq)hasbecome a routine method for global geneexpression profiling.However,its application tolarge‐scale experiments remains limited by costand labor constraints.Here we describe amassively parallel 3′end RNA‐seq(MP3RNA‐seq)method that introduces unique samplebarcodes during reverse transcription to permitsample pooling immediately following this initialstep.MP3RNA‐seq allows for handling of hun-dreds of samples in a single experiment,at acost of about$6 per sample for libraryconstruction and sequencing.MP3RNA‐seq iseffective for not only high‐throughput geneexpression profiling,but also genotyping.Todemonstrate its utility,we applied MP3RNA‐seqto 477 double haploid lines of maize.We iden-tified 19,429 genes expressed in at least 50%ofthe lines and 35,836 high‐quality singlenucleotide polymorphisms for genotypinganalysis.Armed with these data,we performedexpression and agronomic trait quantitativetrait locus(QTL)mapping and identified 25,797expression QTLs for 15,335 genes and 21 QTLsfor plant height,ear height,and relative earheight.We conclude that MP3RNA‐seq is highlyreproducible,accurate,and sensitive forhigh‐throughput gene expression profiling andgenotyping,and should be generally applicableto most eukaryotic species. | Jian Chen Xiangbo Zhang Fei Yi Xiang Gao Weibin Song Haiming Zhao Jinsheng Lai | 2021 | Journal of Integrative Plant Biology2021，63，7： | 1 |
| 6 | Genome-wide Nucleosome Occupancy and Organization Modulates the Plasticity of Gene Transcriptional Status in Maize显示文摘Nucleosomes 是染色质的基本单位由 modulating DNA 可接近性在基因规定起关键作用。然而,他们在调整织物特定的基因抄写的角色 ? 糟糕被理解。这里,我们定序 micrococcal 核酸酶产生的玉米射击和内乳的现在的染色体宽的 nucleosome 地图消化了 nucleosomal DNA。在射击和内乳之间的基因 transcriptional 地位的变化被优先的 nucleosome 损失在 transcriptional 开始地点(+1 nucleosome ) 下游、 transcriptional 结束地点(1 nucleosome ) 在上游的第一 nucleosome 从倡导者和移动伴随。内在地编码 DNA 的 nucleosome 组织大部分与基因的能力被联系在不同纸巾之中改变它的 transcriptional 地位。与织物特定的基因相比,组成地表示了显示出的基因更多读了 5 和 3 个弄空 nucleosome 的区域 ? 象一样进一步 ?+1 nucleosome 到 transcriptional 开始地点和到 transcriptional 结束地点的 1 nucleosome。而且,当使用检验在时, nucleosome 组织更高度比与它的表达式水平与基因 transcriptional 地位的粘性被相关 ? vivo 和预言的 nucleosome 数据。另外,织物特定的基因的翻译效率看起来比组成地表示的基因的那些大。一起拿,我们的结果显示那个内在地编码 DNA 的 nucleosome 组织是重要的在它在调整基因表示层次的角色以外,在决定基因 transcriptional 的粘性地位。 | Jian Chen En Li Xiangbo Zhang Xiaomei Dong Lei Lei Weibin Song Haiming Zhao Jinsheng Lai | 2017 | Molecular Plant2017，10，7： | 1 |
| 7 | Mass Screening is Inevitable to Detect the Curable Early Stage Prostate Cancer显示文摘 | Ling Zhang Weihua Wang Guoyi Ji Hongliang Wang Hongwen Gao Xiangbo Kong Yuzhuo Pan Xuejian Zhao | 2006 | Journal of US-China Medical Science2006，3，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员