|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reconfigurable directional coupler in lithium niobate crystal fabricated by three-dimensional femtosecond laser focal field engineering显示文摘For crystals, depressed cladding waveguides have advantages such as preservation of the spectroscopic as well as non-linear properties and the capability to guide both horizontal and vertical polarization modes, but fabrication is always quite time consuming. In addition, it is usually difficult to couple modes propagating in different depressed cladding waveguides through evanescent field overlap, so it is often required to dynamically reconfigure photonic waveguide devices using external fields for classical or quantum applications. Here, we experimentally demonstrate the single-scan femtosecond laser transverse writing of depressed cladding waveguides to form a 2 × 2 directional coupler inside lithium niobate crystal, which is integrated with two deeply embedded microelectrodes on both sides of the interaction region to reconfigure the coupling. By focal field engineering of the femtosecond laser, we specially generate a three-dimensional longitudinally oriented ring-shaped focal intensity profile composed of 16 discrete spots to simultaneously write the entire cladding region. The fabricated waveguides exhibit good single guided modes in two orthogonal polarizations at 1550 nm. By applying voltage to the deeply embedded microelectrodes fabricated with the femtosecond laser ablation followed by selective electroless plating, we successfully facilitate the light coupling from the input arm to the cross arm and thus actively tune the splitting ratio. These results open new important perspectives in the efficient fabrication of reconfigurable complex three-dimensional devices in crystals based on depressed cladding waveguides. | Qian Zhang Meng Li Jian Xu Zijie Lin Haofeng Yu Min Wang Zhiwei Fang Ya Cheng Qihuang Gong Yan Li | 2019 | Photonics Research2019，7，5： | 7 |
| 2 | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332显示文摘Dear Editor,Since December 2019,the pandemic of coronavirus disease 2019(COVID-19)has taken a heavy toll on global health,creating an urgent need to develop effective strategies for prevention and treatment.The etiological agent,known as severe acute respiratory syndrome coronavirus 2(SARSCoV-2),has infected nearly 229.2 million people worldwide with more than 4.7 million deaths as of September 15,2021.Older age and preexisting health conditions are associated with worse clinical prognosis including higher mortality rates(Zhou et al.,2020).The global race to combat this pandemic has led to rapid deployment of numerous effective vaccines against SARS-CoV-2(Tregoning et al.,2021).However,the emergence of viral variants,including the Delta variant(B.1.617.2),compromised vaccine effectiveness with resurgence of SARS-CoV-2 infection among highly vaccinated population(Keehner et al.,2021).Therefore,development of therapeutics against the more conserved viral targets would be essential to contain the spread of COVID-19 and reduce mortality. | Yao Zhao Chao Fang Qi Zhang Ruxue Zhang Xiangbo Zhao Yinkai Duan Haofeng Wang Yan Zhu Lu Feng Jinyi Zhao Maolin Shao Xiuna Yang Leike Zhang Chao Peng Kailin Yang Dawei Ma Zihe Rao Haitao Yang | 2022 | Protein & Cell2022，13，9： | 6 |
| 3 | Film Cooling Performance of a Row of Dual-fanned Holes at Various Injection Angles显示文摘Film cooling performance about a row of dual-fanned holes with injection angles of 30°, 60 ° and 90° were experimentally investigated at blowing ratios of 1.0 and 2.0. Dual-fanned hole is a novel shaped hole which has both inlet expansion and outlet expansion. A transient thermochromic liquid crystal technique was used to reveal the local values of film cooling effectiveness and heat transfer coefficient. The results show that injection angles have strong influence on the two dimensional distributions of film cooling effectiveness and heat transfer coefficient. For the small injection angle of 30 degree and small blowing ratio of 1.0, there is only a narrow spanwise region covered with film. The increase of injection angle and blowing ratio both leads to the enhanced spanwise film diffusion, but reduced local cooling ability far away from the hole. Injection angles have comprehensive influence on the averaged film cooling effectiveness for various x/d locations. As injection angles are 30 and 60 degree, two bands of high heat transfer coefficients are found in mixing region of the gas and coolant. As injection angle increases to 90 degree, the mixing leads to the enhanced heat transfer region near the film hole. The averaged heat transfer coefficient increases with the increase of injection angle. | LI Guangchao WANG Haofeng ZHANG Wei KOU Zhihai XU Rangshu | 2017 | Journal of Thermal Science2017，26，5： | 4 |
| 4 | Recent progress in the discovery of inhibitors targeting coronavirus proteases显示文摘Coronaviruses(CoVs) can cause highly prevalent diseases in humans and animals. The fatal outbreak of severe acute respiratory syndrome(SARS) and Middle East respiratory syndrome(MERS) highlights the threat posed by this unique virus subfamily. However, no specific drugs have been approved to treat CoV-associated diseases to date. The CoV proteases, which play pivotal roles in viral gene expression and replication through a highly complex cascade involving the proteolytic processing of replicase polyproteins, are attractive targets for drug design. This review summarizes the recent advances in biological and structural studies, together with the development of inhibitors targeting CoV proteases, particularly main proteases(M^(pro)s), which could help develop effective treatments to prevent CoV infection. | Haofeng Wang Song Xue Haitao Yang Cheng Chen | 2016 | Virologica Sinica2016，31，1： | 4 |
| 5 | Phase transformation and liquid density redistribution during solidification of Ni-based superalloy Inconel 718显示文摘The influences of chemical segregation and phase transformation on liquid density variation during solidification of Ni-based supperalloy Inconel 718 were investigated using SEM and EDS. It was found that significant segregation in liquid prompts high Nb phase to precipitate directly from liquid, which results in the redistribution of alloy elements and liquid density in their vicinity. The term 'inter-precipitate liquid density' is therefore proposed and this concept should be applied to determine the solidification behavior of superalloy Inconel 718. | Wang Ling Gong He Zhao Haofeng Dong Jianxin Zhang Maicang | 2012 | China Foundry2012，9，3： | 3 |
| 6 | Improving photosynthesis of microalgae by changing the ratio of light-harvesting pigments显示文摘Changing the ratio of light-harvesting pigments was regarded as an efficient way to improve the photosyn-thesis rate in microalgae, but the underlying mechanism is still unclear. In the present study, a mutant of Anabeana simensis (called SP) was selected from retrieved satellite cul-tures. Several parameters related with photosynthesis, such as the growth, photosynthesis rate, the content of photosyn-thetic pigment, low temperature fluorescence spectrum (77K) and electron transport rate, were compared with those of the wild type. It was found that the change in the ratio of light-harvesting pigments in the mutant led to more efficient light energy transfer and usage in mutant than in the wild type. This may be the reason why the mutant had higher photosynthesis and growth rates. | WANG Gaohong CHEN Lanzhou LI Genbao LI Dunhai HU Chunxiang CHEN Haofeng LIU Yongding SONG Lirong | 2005 | Chinese Science Bulletin2005，50，15： | 3 |
| 7 | Current status of Macaca mulatta in Taihangshan mountains area, Jiyuan, Henan, China 显示文摘 | Lu Jiqi Hou Jinhuai Wang Haofeng | 2007 | International Journal of Primatology2007，25，8： | 1 |
| 8 | Grain refinement effect of La_2(CO_3)_3 on AZ91 magnesium alloy显示文摘The La2(CO3)3 addition makes the grain of AZ91 alloy be refined obviously. The average primary dendrite size of the alloy decreases from 150 to 50 μm. The microstructure of typical dendrite turns into the equal-axed grain with the addition of 2.5 wt.% La2(CO3)3 refiner. The mechanical properties tests indicate that the tensile strength and especially elongation of the alloys are improved with the addition of La2(CO3)3 and their maximum enhancing rates based on the La2(CO3)3-free AZ91 alloy are 26% and 5.2 times at 2.5 wt.% La2(CO3)3 refiner respectively. | WANG Ling ZHAO Haofeng GUO Shengli SU Junyi | 2006 | Rare Metals2006，25，z2： | 1 |
| 9 | The role of process parameters in plasma surface chromising of Ti 2 AlNb-based alloys显示文摘 | Hongyan Wu Pingze Zhang Ling Wang Haofeng Zhao Zhong Xu | 2009 | Applied Surface Science2009，，5： | 1 |
| 10 | Generation of multiple stress waves in silica glss in high fluence femtosecond laser abation 显示文摘 | Hu Haofeng Wang Xiaolei Zhai Hongchen Zhang Nan Wang Pan | 2010 | Applied Physics Letters2010，97，06： | 1 |
| 11 | Hemicelluloses negatively affect lignocellu- lose crystallinity for high biomass digestibility under NaOH and H2SO4 pretreatments in Miscanthus 显示文摘 | Ning Xu Wei Zhang Shuanfeng Ren Fei Liu Chunqiao Zhao Haofeng Liao Zhengdan Xu Jiangfeng Huang Qing Li Ynanyuan Tu Bin Yn Yanting Wang Jianxiang Jiang Jingping Qin Liangcai Peng | 2012 | Biotechnology for Biofu- els2012，5，： | 1 |
| 12 | Solution processable transition metal dichalcogenides-based hybrids for photodetection显示文摘Transition metal dichalcogenides(TMDs), as one of the most promising two-dimensional(2D) materials, have attracted considerable attention for use in photodetection applications over the past few years due to their distinct properties, such as atomic-scale thickness, tunable direct bandgaps, and decent carrier mobilities at room temperature. Compared with pure 2D TMDs, the construction of hybrids consisting of TMDs and other low-dimensional materials can further improve the performance of photodetectors including their spectral range, responsivity and detectivity, which significantly boosts interest in the development of TMDs-based photodetectors. On the other hand, solution-phase synthesis methods provide a facile strategy for the scalable production of TMD hybrids, opening an exciting avenue to develop low-cost devices. In this review, we summarize the material synthesis, characterizations, and photodetection applications of the solution processable TMDs-based hybrids, as well as provide insights into their prospects. | Yingdong Han Jie Wang Haoran Wan Shuang Wang Haofeng Hu Ting-Hui Xiao Zhenzhou Cheng Tiegen Liu | 2019 | Nano Materials Science2019，1，4： | 1 |
| 13 | Crystal structure of monkeypox H1 phosphatase,an antiviral drug target显示文摘Dear Editor,Since its appearance in May 2022,monkeypox has spread to>100 countries and afflicted tens of thousands of people.Individuals infected with monkeypox present a fever,an extensive characteristic rash,and usually swollen lymph nodes(Chatterjee et al.,2022).The number of confirmed cases worldwide continues to grow at a rapid rate,but the treatment to this highly infectious viral disease is still very limited.Identification of new targeted-therapies will be crucial to control of this emerging public health threat. | Wen Cui Haojun Huang Yinkai Duan Zhi Luo Haofeng Wang Tenan Zhang Henry C Nguyen Wei Shen Dan Su Xi Li Xiaoyun Ji Haitao Yang Wei Wang | 2023 | Protein & Cell2023，14，6： | 0 |
| 14 | Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity显示文摘Dear Editor,The coronavirus disease 2019(COVID-19)pandemic is generating a demand for simultaneous vaccine development,which is expected to prevent future outbreaks by eliciting sufficient and protective immunity. | Junyan Han Ning Zhang Danying Chen Yuhuan Gong Guoli Li Yaxian Kong Lin Pu Chen Chen Jingyuan Liu Qi Wang Ju Zhang Xuesen Zhao Juan Du Kai Han Chuan Song Linghang Wang Mingxi Hua Yu Hao Rui Song Yangzi Song Fengting Yu Siyuan Yang Haofeng Xiong Wei Zhang George F.Gao Fujie Zhang Ang Li Hui Zeng Yuhai Bi | 2022 | Science China(Life Sciences)2022，65，1： | 0 |
| 15 | Feature-Grounded Single-Stage Text-to-Image Generation显示文摘Recently,Generative Adversarial Networks(GANs)have become the mainstream text-to-image(T2I)framework.However,a standard normal distribution noise of inputs cannot provide sufficient information to synthesize an image that approaches the ground-truth image distribution.Moreover,the multistage generation strategy results in complex T2I applications.Therefore,this study proposes a novel feature-grounded single-stage T2I model,which considers the“real”distribution learned from training images as one input and introduces a worst-case-optimized similarity measure into the loss function to enhance the model's generation capacity.Experimental results on two benchmark datasets demonstrate the competitive performance of the proposed model in terms of the Frechet inception distance and inception score compared to those of some classical and state-of-the-art models,showing the improved similarities among the generated image,text,and ground truth. | Yuan Zhou Peng Wang Lei Xiang Haofeng Zhang | 2024 | Tsinghua Science and Technology2024，29，2： | 0 |
| 16 | Identifying a melanogenesis-related candidate gene by a high-quality genome assembly and population diversity analysis in Hypsizygus marmoreus显示文摘Hypsizygus marmoreus is one of the most important edible fungi in Basidiomycete division and includes white and gray strains.However,very limited knowledge is known about the genomic structures and the genetic basis for the white/gray diversity of this mushroom.Here,we report the near-complete high-quality H.marmoreus genome at the chromosomal level.Comparative genomics analysis indicates that chromosome structures were relatively conserved,and variations in collinearity and chromosome number were mainly attributed by chromosome split/fusion events in Aragicales,whereas the fungi genome experienced many genomic chromosome fracture,fusion,and genomic replication events after the split of Aragicales from Basidiomycetes.Resequencing of 57 strains allows us to classify the population into four major groups and associate genetic variations with morphological features,indicating that white strains were not originated independently.We further generated genetic populations and identified a cytochrome P450 as the candidate causal gene for the melanogenesis in H.marmoreus based on bulked segregant analysis (BSA)and comparative transcriptome analysis.The high-quality H.marmoreus genome and diversity data compiled in this study provide new knowledge and resources for the molecular breeding of H.marmoreus as well as the evolution of Basidiomycete. | Gang Wang Lianfu Chen Weiqi Tang Yuanyuan Wang Qing Zhang Hongbo Wang Xuan Zhou Haofeng Wu Lin Guo Meijie Dou Lei Liu Baiyu Wang Jingxian Lin Baogui Xie Zhengchao Wang ZhongJian Liu Ray Ming Jisen Zhang | 2021 | Journal of Genetics and Genomics2021，48，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员