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| 1 | Relative humidity reconstruction for northwestern China's Altay Mountains using tree-ring δ^(18)O显示文摘Relative humidity is an important factor in water and water vapor feedback cycles.In this study,we established a 222-year annual tree-ring δ^(18)O chronology for Siberian larch(Larix sibirica Ldb.)from the Altay Mountains in northwestern China.Climate response analyses revealed that the relative humidity was the primary factor limiting tree-ring δ^(18)O fractionation.Based on our analysis,tree-ring δ^(18)O can be used to reconstruct the July–August relative humidity based on both a reasonable mechanism of tree-ring δ^(18)O fractionation and a statistically significant regression model.We used this model to reconstruct variations in the July–August relative humidity,and the model explained 47.4% of the total variation in the measured relative humidity data from 1961 to 2011.The relative humidity in the study area increased from 1900 to the 1990s and decreased thereafter.Two regime-shift dry periods were detected during the study period(one from 1817 to 1830 and the other from 2004 to 2011). | Guobao Xu Xiaohong Liu Dahe Qin Tuo Chen Wenzhi Wang Guoju Wu Weizhen Sun Wenling An Xiaomin Zeng | 2014 | Chinese Science Bulletin2014，59，2： | 14 |
| 2 | Moisture variations over the past millennium characterized by Qaidam Basin tree-ring δ^(18)O显示文摘High-resolution tree-ring δ18O chronologies covering the last millennium,although scarce,are essential in understanding patterns of climatic changes in the northeastern region of the Qinghai-Tibetan Plateau.For this study,a tree-ring δ18O chronology with a temporal resolution of 3-years was developed from the long-lived Qilian juniper(Sabina przewalskii Kom.),extending back in time to AD 991.This long δ18O chronology was significantly correlated with the yearly δ18O in tree rings during the common period from 1800 to 2006,and was an effective proxy for relative humidity during the growing season.A low-frequency moisture pattern signified the occurrence of a slight drought during the Medieval Climate Anomaly,a marked occurrence of a wet period during the Little Ice Age,and a trend in increasing moisture levels,although lower than average,alongside the Twentieth Century warming trend.Comparisons to other hydroclimatic reconstructions indicate that this tree-ring18O chronology serves as a reliable paleo-humidity proxy for the Qaidam Basin as well as documenting details of past humidity levels in the region. | WANG WenZhi LIU XiaoHong XU GuoBao SHAO XueMei QIN DaHe SUN WeiZhen AN WenLing ZENG XiaoMin | 2013 | Chinese Science Bulletin2013，58，32： | 14 |
| 3 | Comparison of the short-term and long-term outcomes of laparoscopic hysterectomies and of abdominal hysterectomies: a case study of 4,895 patients in the Guangxi Zhuang Autonomous Region, China显示文摘Background: To evaluate the short-term and long-term outcomes after laparoscopic hysterectomy(LH) compared with abdominal hysterectomy(AH) in case of benign gynecological disease. Methods: A multi-center cohort retrospective comparative study of population among 4,895 hysterectomies(3,539 LH vs.1,356 AH) between 2007 and 2013 was involved. Operative time(OT), estimated blood loss(EBL), intra-operative and post-operative complications, passing flatus; days with indwelling catheter, questionnaires covering pelvic floor functions and sexual functions were assessed.Results: The EBL(174.1±157.4 vs. 263.1±183.2 cc, LH and AH groups, respectively), passing flatus(38.7±14.1 vs. 48.1±13.2 hours), days with indwelling catheter(1.5±0.6 vs. 2.2±0.8 days), use of analgesics(6.5% vs. 73.1%), intra-operative complication rate(2.4% vs. 4.1%), post-operative complication rate(2.3% vs. 5.7%), post-operative constipation(12.1% vs. 24.6%), mild and serious stress urinary incontinence(SUI) post-operative(P<0.001; P=0.014), and proportion of Female Sexual Functioning Index(FSFI) total score <26.55 post-operative(P<0.001) of the LH group were significantly less than those of AH group. There wereno significant differences in OT(106.5±34.5 vs. 106.2±40.3 min) between the two groups.Conclusions: LH is a safe and efficient operation for improving patients' long-term quality of life(Qo L), and LH is a cost-effectiveness procedure for treating benign gynecological disease. LH is superior to AH due to reduced EBL, reduced post-operative pain and earlier passing flatus. | Hongying He Zhijun Yang Dingyuan Zeng Jiangtao Fan Xiaoxia Hu Yuan Ye Hua Bai YanmingJiang Zhong Lin Zhiying Lei Xinlin Li Lian Li Jinghua Gan Ying Lan Xiongzhi Tang Danxia Wang Junsong Jiang Xiaoyan Wu Meiying Li Xiaoqing Ren Xiaomin Yang Mei Liu Qinmei Wang Fuyan jiang Li Li | 2016 | Chinese Journal of Cancer Research2016，28，2： | 6 |
| 4 | Multi-layered micro/nanofibrous nonwovens for functional face mask filter显示文摘The worldwide COVID-19 pandemic has led to an attention on the usage of personal protective face masks.However,the longevity and safety of the commercial face masks are limited due to the charge dissipation of the electret meltblown nonwovens,which are dominate in the face mask filters.Herein,we design a type of multi-layer structured nonwovens using meltblowing and electrospinning technologies.The complex nonwovens involving meltblown and electrospun fibers are designed to possess multilevel fiber diameters and pore sizes.The micro/nanofibers with porous and wrinkled surface morphologies can well capture particulate matters(PMs),and the multilevel pore sizes contribute to low air resistance under high filtration efficiency.Airflow field simulation was carried out to understand the pressure distribution within the nonwovens in the filtration process.Meanwhile,by adding Ag nanoparticles(AgNPs)as additives,the nonwovens exhibit excellent antibacterial performance.The resultant nonwovens exhibit filtration efficiency of 99.1%for PM0.3 and low pressure drop of 105 Pa under the 10.67 cm/s inlet air velocity,and antibacterial rate of>99.99%for Escherichia coli.These performances and functions make the designed complex nonwovens a promising filter core for face masks. | Yuanqiang Xu Xiaomin Zhang Defang Teng Tienan Zhao Ying Li Yongchun Zeng | 2022 | Nano Research2022，15，8： | 6 |
| 5 | Sedimentary Conditions of Evaporites in the Late Jurassic Xiali Formation,Qiangtang Basin:Evidence from Geochemistry Records显示文摘The Qiangtang Basin(QB), located in the central Tibetan Plateau, is a Jurassic marine basin and one of the most important prospective salt resource belts in China. In recent decades, many outcrops of gypsiferous bed have been found in the Jurassic marine strata in the basin. Salt springs with abnormally high sodium(Na^+) contents had been identified in the Late Jurassic Xiali Formation(Fm.) in the basin in the last years. However, to date, no potash or halite deposits have been identified in the QB. Gypsum outcrops and salt springs are very important signs in the investigation of halite and potash deposits. Therefore, the Xiali Fm. is a potentially valuable layer to evaluate for the possible presence of halite and potash deposits in the basin. However, few studies have explored the formation conditions of evaporites in the unit. Here, we present detailed geochemical records from the Yanshiping section related to the study of the formation conditions of evaporites in the Xiali Fm. of the QB. Climate proxies based on the obviously increased anion concentrations of SO_4(2-) and Cl^- and the significant correlation coefficients of Ca2+-SO42-(R = 0.985) and Na^+-Cl^-(R = 0.8974) reveal that the upper member of the Xiali Fm.(the upper Xiali Fm.) formed under an arid climate and evolved into the sulfate phase or early chloride phase. Provenance proxies based on the obviously increased K^+ and Na^+ ion concentrations and the significant correlation coefficient of Na^+-Cl^-(R = 0.8974) suggest that the upper Xiali Fm. featured optimal provenance conditions for the possible formation of halite deposits. The regression and the semi-closed tidal flat environment in the upper Xiali Fm. were favorable for the formation of potash and halite deposits. The low Mg^(2+) /Ca^(2+) values(mean value = 1.82) and significant Na^+-Cl^- correlation coefficient(R = 0.8974) also suggest that the upper Xiali Fm. is the layer most likely to contain potential halite deposits. In addition, the macroscopic correlations of tectonism, provenance, paleoclimate, saliferous strata and sedimentary environment between the QB and the adjoining Amu Darya Basin in Central Asia reveal that the two basins shared similar geologic settings that were favorable for the formation of evaporites during the Late Jurassic. Therefore, the upper Xiali Fm. is a valuable layer to explore for halite deposit and may be potentially valuable in the future exploration for potash deposits in the QB. | SONG Chunhui ZENG Yongyao YAN Maodu FANG Xiaomin FENG Ying PAN Jiaqiu LIU Xifang MENG Qingquan HU Chunhua ZHONG Sirui | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 4 |
| 6 | Increased mercury pollution revealed by tree rings from the China's Tianshan Mountains显示文摘Mercury (Hg)can be transported globally by the atmospheric circulation and it accumulates and biomagnifies along food chains [1,2].Due to its threats to human health and wildlife when converted to the neurotoxin methyl mercury,variations in Hg concentration in various ecosystems were paid more attention by scientists recently.Natural processes such as geothermal activities, volcanic activities,and weathering of Hg-containing rocks,can release a mass of Hg to the environment.Anthropogenic emissions had become the main atmospheric pollution source since the Industrial Revolution.A recent study indicated that half of the Hg presented in atmosphere was sourced from human activities and about 73%total mercury was released after 1850[3].Aiming to reduce the impact of Hg to environmental and human health,UNEP (United Nations Environment Programme)passed the Minamata Convention in 2013to limit Hg emission through contro|ling technologies on air pollution. | Huhu Kang Xiaohong Liu Junming Guo Guobao Xu Guoju Wu Xiaomin Zeng Bo Wang Shichang Kang | 2018 | Science Bulletin2018，63，20： | 4 |
| 7 | The diazotrophic community in oat rhizosphere: effects of legume intercropping and crop growth stage显示文摘In this study, the abundance, diversity and structure of the diazotrophic community in oat rhizosphere soil in three cropping systems and at two oat growth stages were investigated using real-time PCR and Illumina MiSeq sequencing. The nifH gene abundance in oat-soybean intercropping (OSO) and oat-mungbean intercropping (OMO) was significantly greater than that in sole oat (O), but the nifH gene abundance significantly decreased at the later stage in all the treatments. Alpha diversity indices in OSO and OMO were higher at the heading stage, but lower at the maturity stage than that in O. Bradyrhizobium and Skermanella were the dominant genera identified in all samples, with an average proportion of 35.8% and 12.4%, respectively. The proportion of dominant genera showed significant differences and varied with cropping system and growth stage. Principal component analysis showed that growth stage had a stronger effect than intercropping on the diazotrophic community structure. However, Mantel test and redundancy analysis showed there was no environmental factor significantly correlated to the diazotrophic community structure. Our results demonstrate that intercropping had a weaker effect than growth stage on the abundance, diversity and structure of the diazotrophic community in oat rhizosphere soil. | Yadong YANG Xiaomin FENG Yuegao HU Zhaohai ZENG | 2019 | Frontiers of Agricultural Science and Engineering2019，6，2： | 3 |
| 8 | Performance of common buckwheat(Fagopyrum esculentum M.) supplied with selenite or selenate for selenium biofortification in northeastern China显示文摘Selenium(Se)deficiency commonly occurs in soils of northeastern China and leads to insufficient Se intake by humans.A two-year field study of Se biofortification of common buckwheat supplied with 40 g Se ha^(-1)as selenite(Se(IV)),selenate(Se(VI)),or a combination(1/2 Se(IV+VI))was performed to investigate Se accumulation and translocation in plants and determine the effects of different forms of Se on the grain yield,biomass production,and Se use efficiency of plants and seeds.Se application increased seed Se concentrations to 47.1–265.1μg kg^(-1).Seed Se concentrations following Se(VI)or 1/2 Se(IV+VI)treatment exceeded 100μg kg^(-1),an amount suitable for crop Se biofortification.Se concentration in shoots and roots decreased with plant development,and Se translocation from root to shoot in Se(IV)-treated plants was lower than that in plants treated with 1/2 Se(IV+VI)and Se(VI).Both grain yield and biomass production increased under 1/2 Se(IV+VI)treatment,with grain yields reaching 1663.8 and 1558.5 kg ha^(-1)in 2015 and 2016,respectively,reflecting increases of 11.0% and 10.3% over those without Se application.The Se use efficiency of seeds and plants under Se(VI)treatment was significantly higher than those under 1/2 Se(IV+VI)and Se(IV)treatments.Thus,application of selenate could result in higher Se accumulation in buckwheat seeds than application of the other Se sources,but the combined application of selenate and selenite might be an alternative approach for improving buckwheat grain yield by Se biofortification in northeastern China. | Ying Jiang Xiaomin Feng Yadong Yang Xiangxue Qi Yongfeng Ren Youhui Gao Weidong Liu Yuegao Hu Zhaohai Zeng | 2018 | The Crop Journal2018，6，4： | 3 |
| 9 | Multi-class cancer classification through gene expression profiles: microRNA versus mRNA显示文摘Both microRNA (miRNA) and mRNA expression profiles are important methods for cancer type classification. A comparative study of their classification performance will be helpful in choosing the means of classification. Here we evaluated the classification performance of miRNA and mRNA profiles using a new data mining approach based on a novel SVM (Support Vector Machines) based recursive feature elimination (nRFE) algorithm. Computational experiments showed that information encoded in miRNAs is not sufficient to classify cancers; gut-derived samples cluster more accurately when using mRNA expression profiles compared with using miRNA profiles; and poorly differentiated tumors (PDT) could be classified by mRNA expression profiles at the accuracy of 100% versus 93.8% when using miRNA profiles. Furthermore, we showed that mRNA expression profiles have higher capacity in normal tissue classifications than miRNA. We concluded that classification performance using mRNA profiles is superior to that of miRNA profiles in multiple-class cancer classifications. | Sihua Peng Xiaomin Zeng Xiaobo Li Xiaoning Peng Liangbiao Chen | 2009 | Journal of Genetics and Genomics2009，36，7： | 1 |
| 10 | Improvement in Resolution of Multiphoton Scanning Structured Illumination Microscopy via Harmonics显示文摘We describe a multiphoton(mP)-structured illumination microscopy(SIM)technique,which demonstrates substantial improvement in image resolution compared with linear SIM due to the nonlinear response of fluorescence.This nonlinear response is caused by the effect of nonsinusoidal structured illumination created by scanning a sinusoidally modulated illumination to excite an mP fluorescence signal.The harmonics of the structured fluorescence illumination are utilised to improve resolution.We present an mP-SIM theory for reconstructing the super-resolution image of the system.Theoretically,the resolution of our m P-SIM is unlimited if all the high-order harmonics of the nonlinear response of fluorescence are considered.Experimentally,we demonstrate an 86 nm lateral resolution for two-photon(2P)-SIM and a 72 nm lateral resolution for second-harmonic-generation(SHG)-SIM.We further demonstrate their application by imaging cells stained with F-actin and collagen fibres in mouse-tail tendon.Our method can be directly used in commercial mP microscopes and requires no specific fluorophores or high-intensity laser. | Lei Wang Xiaomin Zheng Jie Zhou Meiting Wang Jiajie Chen Youjun Zeng Gaixia Xu Ying Wang Haixia Qiu Yonghong Shao Junle Qu Bruce Zhi Gao Ying Gu | 2022 | Engineering2022，，9： | 1 |
| 11 | Tree-ring δ^(15)N of Qinghai spruce in the central Qilian Mountains of China:Is pre-treatment of wood samples necessary?显示文摘A knowledge of the tree-ring stable nitrogen isotope ratio(δ^(15)N)can deepen our understanding of forest ecosystem dynamics by indicating the long-term availability,cycling and sources of nitrogen(N).However,the radial mobility of N blurs the interannual variations in the long-term N records.Previous studies of the chemical extraction of tree rings before analysis had produced inconsistent results and it is still unclear whether it is necessary to pre-treat wood samples from specific tree species to remove soluble N compounds before determining theδ^(15)N values.We compared the effects of pre-treatment with organic solvents and hot ultrapure water on the N concentration andδ^(15)N of tree rings from endemic Qinghai spruce(Picea crassifolia)growing in the interior of the central Qilian Mountains,China,during the last 60 a.We assessed the effects of different preparation protocols on the removal of the labile N compounds and investigated the need to pre-treat wood samples before determining theδ^(15)N values of tree rings.Increasing trends of the tree-ring N concentration were consistently observed in both the extracted and unextracted wood samples.The total N removed by extraction with organic solvents was about 17.60%,with a significantly higher amount in the sapwood section(P<0.01).Theδ^(15)N values of tree rings decreased consistently from 1960 to 2019 in both the extracted and unextracted wood samples.Extraction with organic solvents increased theδ^(15)N values markedly by about 5.2‰and reduced the variations in theδ^(15)N series.However,extraction with hot ultrapure water had little effect,with only a slight decrease in theδ^(15)N values of about 0.5‰.Our results showed that the radial pattern in the inter-ring movement of N in Qinghai spruce was not minimized by extraction with either organic solvents or hot ultrapure water.It is unnecessary to conduct hot ultrapure water extraction for the wood samples from Qinghai spruce because of its negligible effect on the removal of the labile N.Theδ^(15)N variation trend of tree rings in the unextracted wood samples was not influenced by the heartwood-sapwood transition zone.We suggest that theδ^(15)N values of the unextracted wood samples of the climate-sensitive Qinghai spruce could be used to explore the ecophysiological dynamics while focusing on the long-term variations. | WANG Ziyi LIU Xiaohong WANG Keyi ZENG Xiaomin ZHANG Yu GE Wensen KANG Huhu LU Qiangqiang | 2022 | Journal of Arid Land2022，14，6： | 1 |
| 12 | Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer显示文摘Epigenetic therapies that cause genome-wide epigenetic alterations,could trigger local interplay between different histone marks,leading to a switch of transcriptional outcome and therapeutic responses of epigenetic treatment.However,in human cancers with diverse oncogenic activation,how oncogenic pathways cooperate with epigenetic modifiers to regulate the histone mark interplay is poorly understood.We herein discover that the hedgehog(Hh)pathway reprograms the histone methylation landscape in breast cancer,especially in triple-negative breast cancer(TNBC).This facilitates the histone acetylation caused by histone deacetylase(HDAC)inhibitors and gives rise to new therapeutic vulnerability of combination therapies.Specifically,overexpression of zinc finger protein of the cerebellum 1(ZIC1)in breast cancer promotes Hh activation,facilitating the switch of H3K27 methylation(H3K27me)to acetylation(H3K27ac).The mutually exclusive relationship of H3K27me and H3K27ac allows their functional interplay at oncogenic gene locus and switches therapeutic outcomes.Using multiple in vivo breast cancer models including patient-derived TNBC xenograft,we show that Hh signaling-orchestrated H3K27me and H3K27ac interplay tailors combination epigenetic drugs in treating breast cancer.Together,this study reveals the new role of Hh signaling-regulated histone modifications interplay in responding to HDAC inhibitors and suggests new epigenetically-targeted therapeutic solutions for treating TNBC. | Xiaomin Wang Jun Xu Yiming Sun Siyuwei Cao Hanlin Zeng Nan Jin Matthew Shou Shuai Tang Yi Chen Min Huang | 2023 | Acta Pharmaceutica Sinica B2023，13，6： | 1 |
| 13 | New insights into seismic stratigraphy of shallow-water progradational sequences: Subseismic clinoforms显示文摘 | Zeng Hongliu Zhu Xiaomin Zhu Rukai | 2013 | Interpretation2013，1，1： | 1 |
| 14 | Stratal Slice Recognition of Thin Shallow-Water Delta Sandbodies in the Songliao Basin显示文摘Objective China’s petroleum exploration has entered a new stage of finding deeply buried thin sandbodies for the abundant oil resources they contain.Here thin sandbodies refer to those less than 10 m in thickness,or even less than 1–2 m.It is difficult to depict thin-layer sandbodies of different genetic types using conventional core,well logging and seismic data due to their limited vertical resolution | ZHU Xiaomin ZENG Hongliu DONG Yanlei ZHU Shifa | 2016 | Acta Geologica Sinica(English Edition)2016，90，2： | 1 |
| 15 | Application and verification of simultaneous determination of cellulose δ^(13)C and δ^(18)O in Picea shrenkiana tree rings from northwestern China using the high-temperature pyrolysis method显示文摘Stable isotopes in tree-ring cellulose provide important data in ecological,archaeological,and paleoenvironmental researches,thereby,the demand for stable isotope analyses is increasing rapidly.Simultaneous measurement of cellulose δ^(13)C and δ^(18)O values from tree rings would reduce the cost of isotopic commodities and improve the analytical efficiency compared with conventional separate measurement.In this study,we compared the δ^(13)C and δ^(18)O values of tree-ringα-cellulose from Tianshan spruce(Picea schrenkiana)in an arid site in the drainage basin of the Urumqi River in Xinjiang of northwestern China based on separate and simultaneous measurements,using the combustion method(at1050°C)and the high-temperature pyrolysis method(at 1350°C and 1400°C).We verified the results of simultaneous measurement using the outputs from separate measurement and found that both methods(separate and simultaneous)produced similar δ^(13)C values.The two-point calibrated method improved the results(range and variation)of δ^(13)C and δ^(18)O values.The mean values,standard deviations,and trends of the tree-ring δ^(13)C obtained by the combustion method were similar to those by the pyrolysis method followed by two-point calibration.The simultaneously measured δ^(18)O from the pyrolysis method at 1400°C had a nearly constant offset with that the pyrolysis method at 1350°C due to isotopic-dependence on the reaction temperature.However,they showed similar variations in the time series.The climate responses inferred from simultaneously and separately measured δ^(13)C and δ^(18)O did not differ between the two methods.The tree-ring δ^(13)C and δ^(18)O values were negatively correlated with standardized precipitation evapotranspiration index from May to August.In addition,the δ^(18)O was significantly correlated with temperature(positive),precipitation(negative),and relative humidity(negative)from May to August.The tree-ring δ^(13)C and δ^(18)O values determined simultaneously through the high-temperature pyrolysis method could produce acceptable and reliable stable isotope series.The simultaneous isotopic measurement can greatly reduce the cost and time requirement compared with the separate isotopic measurement.These results are consistent with the previous studies at humid sites,suggesting that the simultaneous determination of δ^(13)C and δ^(18)O in tree-ringα-cellulose can be used in wide regions. | XU Guobao LIU Xiaohong SUN Weizhen CHEN Tuo ZHANG Xuanwen ZENG Xiaomin WU Guoju WANG Wenzhi QIN Dahe | 2018 | Journal of Arid Land2018，10，6： | 1 |
| 16 | Research on the Contemporary Condition and Countermeasures of Higher Vocational College English Teaching显示文摘 | Xiaomin Zeng | 2016 | International Journal of Technology Management2016，，2： | 1 |
| 17 | Hugan Qingzhi Exerts Anti-Inflammatory Effects in a Rat Model of Nonalcoholic Fatty Liver Disease显示文摘 | WaiJiao Tang Lu Zeng JinJin Yin YuFa Yao LiJuan Feng XiaoRui Yao XiaoMin Sun BenJie Zhou Yoshiji Ohta | 2015 | Evidence-Based Complementary and Alternative Medicine2015，，： | 1 |
| 18 | Identification of novel human glioblastoma-specific transcripts byserial analysis of gene expression data mining显示文摘 | Yanlin Su Jie Xiong Zhitong Bing Xiaomin Zeng Yong Zhang Xiaohua Fu Xiaoning Peng | 2013 | Cancer Biomarkers2013，，5： | 1 |
| 19 | An Adap-tive Iterative Method for Downward Continuation ofPotential Field Data from a Horizontal Plane 显示文摘 | Zeng Xiaomin Li Xihai Su Juan | 2013 | Geophysics2013，78，4： | 1 |
| 20 | Identification Marks of Cretaceous Shallow-Water Delta in the Songliao Basin,China显示文摘Objective Shallow-water deltas are now a research focus of international sedimentology.Researchers have recently discovered that water depth is an important controlling factor for the development of shallow deltas,and that significant differences exist between shallow-water deltas and the traditional Gilbert deltas.The identification | ZHU Xiaomin LI Shunli ZENG Hongliu DONG Yanlei ZHU Shifa | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 0 |
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