|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Fhe roles and functional mechanisms of interleukin-17 amily cytokines in mucosal immunity显示文摘 | Xinyang Song Xiao He Xiaoxia Li Youcun Qian | 2016 | Cellular & Molecular Immunology2016，13，4： | 29 |
| 2 | Optimal Harvesting and Stability for a Predator-prey System with Stage Structure显示文摘The dynamics of a predator-prey system, where prey population has two stages, an immature stage and a mature stage with harvesting, the growth of predator population is of Lotka-Volterra nature, are modelled by a system of retarded functional differential equations. We obtain conditions for global asymptotic stability of three nonnegative equilibria and a threshold of harvesting for the mature prey population. The effect of delay on the population at positive equilibrium and the optimal harvesting of the mature prey population are also considered. | Xin-yu Song, Lan-sun ChenDepartment of Mathematics. Xinyang Teachers College, Henan 464000, ChinaInstitute of Mathematics, Academy of Mathematics and System Sciences, Chinese Academy of Sciences, Beijing100080, China | 2002 | Acta Mathematicae Applicatae Sinica2002，18，3： | 11 |
| 3 | 紊乱的肺部菌群通过分泌外膜囊泡调控白介素-17B的产生促进肺纤维化显示文摘文章简介粘膜微生态一直是当前免疫学领域的研究热点,它已经被证明广泛参与多种粘膜组织免疫稳态的维持以及相关疾病的发生。该团队多年来围绕粘膜微生态与白介素-17家族细胞因子做了一系列研究工作,一方面肠癌发生过程中紊乱的微生态菌群可以通过调控IL-17C的产生促进肠癌的发生,另一方面肠道中微生态菌群也可以通过调控IL-17A的分泌促进肠道损伤修复。尽管如此,目前我们对肺组织中微生态的功能尚知之甚少。 | 杨大平 Xi Chen Jingjing Wang Qi Lou Yunwei Lou Li Li Honglin Wang Jiangye Chen Meng Wu Xinyang Song 钱友存 | 2020 | 科学新闻2020，，2： | 3 |
| 4 | Impaired Parahippocampal Gyrus-Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease显示文摘The parahippocampal gyrus-orbitofrontal cortex(PHG-OFC)circuit in humans is homologous to the postrhinal cortex(POR)-ventral lateral orbitofrontal cortex(vlOFC)circuit in rodents.Both are associated with visuospatial malfunctions in Alzheimer’s disease(AD).However,the underlying mechanisms remain to be elucidated.In this study,we explored the relationship between an impaired POR-vlOFC circuit and visuospatial memory deficits through retrograde tracing and in vivo local field potential recordings in 5XFAD mice,and investigated alterations of the PHG-OFC circuit by multi-domain magnetic resonance imaging(MRI)in patients on the AD spectrum.We demonstrated that an impaired glutamatergic POR-vlOFC circuit resulted in deficient visuospatial memory in 5XFAD mice.Moreover,MRI measurements of the PHG-OFC circuit had an accuracy of 77.33%for the classification of amnestic mild cognitive impairment converters versus non-converters.Thus,the PHG-OFC circuit explains the neuroanatomical basis of visuospatial memory deficits in AD,thereby providing a potential predictor for AD progression and a promising interventional approach for AD. | Lin Zhu Zan Wang Zhanhong Du Xinyang Qi Hao Shu Duan Liu Fan Su Qing Ye Xuemei Liu Zheng Zhou Yongqiang Tang Ru Song Xiaobin Wang Li Lin Shijiang Li Ying Han Liping Wang Zhijun Zhang | 2020 | Neuroscience Bulletin2020，36，8： | 2 |
| 5 | ITO/Cu multilayer electrodes for high-brightness electrochromic displays显示文摘Fabry-Perot(F-P)nanocavity-type electrochromic devices with multicolor tunability have attracted significant interest in the past two years for their potential uses in a wide variety of applications,such as electronic display,military camouflage,and dynamic decoration.However,challenges such as insufficient brightness,lengthy switching times,and poor cycling stability have yet to be overcome.Herein,we demonstrate electrochromic electrodes based on ITO/Cu as both the current collector and the reflective layer,with WO_(3 )as the electrochromic material,forming a unique three-layered structure.The constituted WO_(3 )/ITO/Cu films present a high brightness value of about 84%before coloration,and a decent brightness value of 48%after coloration at−0.8V.Moreover,a fast switching time between different coloration states(tc=2.2s;tb=1s)is recorded,attributed to the extremely low sheet resistivity of the ITO/Cu current collector.The films also reveal excellent electrochemical cycling stability across 2000 cycles. | Xueqing Tang Zishou Hu Zhen Wang Jian Chen Xinyang Mu Ge Song Peiyan Sun Zhengji Wen Jiaming Hao Shan Cong Zhigang Zhao | 2022 | eScience2022，2，6： | 1 |
| 6 | IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases 显示文摘 | Xinyang Song Youcun Qian | 2013 | Cel- lular Signalling2013，，25： | 1 |
| 7 | Characteristics of compensatory mutations in the rpoC gene and their association with compensated transmission of Mycobacterium tuberculosis显示文摘The aim of this study was to characterize rpoC gene mutations in Mycobacterium tuberculosis(MTB)and investigate the factors associated with rpoC mutations and the relation between rpoC mutations and tuberculosis(TB)transmission.A total of 245 MTB clinical isolates from patients with TB in six provinces and two municipalities in China were characterized based on gene mutations through DNA sequencing of rpoC and rpoB genes,phenotyping via standard drug susceptibility testing,and genotypic profiling by mycobacterial interspersed repetitive unit-variable number tandem repeat(MIRU-VNTR)typing.Approximately 36.4%of the rifampinresistant isolates harbored nonsynonymous mutations in the rpoC gene.Twenty-nine nonsynonymous single mutations and three double mutations were identified.The rpoC mutations at locus 483(11.3%)were predominant,and the mutations at V483G,W484G,I491V,L516P,L566R,N698K,and A788E accounted for 54.5%of the total detected mutations.Fifteen new mutations in the rpoC gene were identified.Rifampin resistance and rpoB mutations at locus 531 were significantly associated with rpoC mutations.MIRU-VNTR genotype results indicated that 18.4%of the studied isolates were clustered,and the rpoC mutations were not significantly associated with MIRU-VNTR clusters.A large proportion of rpoC mutation was observed in the rifampicin-resistant MTB isolates.However,the findings of this study do not support the association of rpoC mutation with compensated transmissibility. | Shengfen Wang Yang Zhou Bing Zhao Xichao Ou Hui Xia Yang Zheng Yuanyuan Song Qian Cheng Xinyang Wang Yanlin Zhao | 2020 | Frontiers of Medicine2020，14，1： | 0 |
| 8 | GMTS: GNN-based multi-scale transformer siamese network for remote sensing building change detection显示文摘With the remarkable success of change detection(CD)in remote sensing images in the context of deep learning,many convolutional neural network(CNN)based methods have been proposed.In the current research,to obtain a better context modeling method for remote sensing images and to capture more spatiotemporal characteristics,several attention-based methods and transformer(TR)-based methods have been proposed.Recent research has also continued to innovate on TR-based methods,and many new methods have been proposed.Most of them require a huge number of calculation to achieve good results.Therefore,using the TR-based mehtod while maintaining the overhead low is a problem to be solved.Here,we propose a GNN-based multi-scale transformer siamese network for remote sensing image change detection(GMTS)that maintains a low network overhead while effectively modeling context in the spatiotemporal domain.We also design a novel hybrid backbone to extract features.Compared with the current CNN backbone,our backbone network has a lower overhead and achieves better results.Further,we use high/low frequency(HiLo)attention to extract more detailed local features and the multi-scale pooling pyramid transformer(MPPT)module to focus on more global features respectively.Finally,we leverage the context modeling capabilities of TR in the spatiotemporal domain to optimize the extracted features.We have a relatively low number of parameters compared to that required by current TR-based methods and achieve a good effect improvement,which provides a good balance between efficiency and performance. | Xinyang Song Zhen Hua Jinjiang Li | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
| 9 | Heteroatomic Modification of Solid-Waste-Based Mesoporous Carbon for Volatile Organic Compound Adsorption显示文摘Solid-waste-based activated carbon(AC)was utilized as a carbon source to synthesize a series of carbon-based functional material RAC-X(X=P and S,where P and S denote phosphoric and sulfuric acids,respectively).The toluene adsorption capacities of the regeneration AC(RAC)samples can be significantly improved by adopting the heteroatomic modification strategy.RAC-P and RAC-S have the same specific surface area(1156 m^(2)/g)and similar porous structures.However,they have different toluene adsorption capacities,with 316.22 mg/g for RAC-P and 460.12 mg/g for RAC-S,which are 1.6 and 2.4 times greater than that for RAC.The X-ray photoelectron spectroscopy measurements showed that the increase in the amount ofπ–π^(2)chemical bond over the AC surface results in the improvement of the toluene adsorption performance.The density functional theory results showed that the S-containing functional groups loaded near the defect sites of RAC-S promote toluene adsorption.Moreover,reusability tests showed that RAC-S still retains 86%of its adsorption activity after four consecutive adsorption–desorption experiments.This indicates that the heteroatomic modification method affords excellent toluene adsorption performance and recycling practicability,which not only is beneficial for achieving the rational utilization of solid waste resources but also provides a practical method for the efficient elimination of volatile organic compounds. | Liu Jun Li Zhi Xu Ke Zhang Xinyang Li Yunpeng Wang Ya Zhang Yongfa Yang Song Liu Shoujun Li Junhua | 2023 | China Petroleum Processing & Petrochemical Technology2023，25，1： | 0 |
| 10 | Deep eutectic solvent-based gel electrolytes for flexible electrochromic devices with excellent high/low temperature durability显示文摘With the increasing interest in the application of electrochromism to flexible and wearable electronics in recent years,flexible electrochromic devices(ECDs)that can function at extreme temperatures are required.However,the functionalities of flexible ECDs are severely hampered by the inadequate choice of electrolytes,which might ultimately result in performance fading during low-and high-temperature operations.Here,we develop a deep eutectic solvent(DES)-based gel electrolyte that can maintain its optical,electrical,and mechanical properties over a wide range of temperatures(-40 to 150℃),exhibiting an extremely high visible-range transmittance over 90%,ion conductivity of 0.63 mS cm^(-1),and fracture strain exceeding 2000%.Owing to the excellent processability of the DES-based electrolytes,provided by dynamic interactions such as the lithium and hydrogen bonding between the DES and polymer matrix,a directly written patterning in ECDs is realized for the first time.The fabricated ECDs exhibit an excellent electrochromic behavior superior to the behavior of the ECDs fabricated with traditional gel electrolytes.The introduction of such DES-based electrolytes is expected to pave the way for a widespread application of electrochromic products. | Peiyan Sun Jian Chen Yaowu Li Xueqing Tang Hongzhao Sun Ge Song Xinyang Mu Taoyang Zhang Xiuling Zha Feifan Li Yanfeng Gao Shan Cong Zhigang Zhao | 2023 | InfoMat2023，5，2： | 0 |
| 11 | PREDATOR-PREY SYSTEM WITH STAGE STRUCTURE AND DELAY显示文摘A system of retarded functional differential equations is proposed as a predator-prey model with stage structure in the prey.The invariance of non-negativity,nature of boundary equilibria and global stability are analyzed.It is shown that in this model the time delay can make a stable equilibrium become unstable and even a switching of stabilities. | Ye Kaili Song XinyuDept. of Math.,Xinyang Teachers College,Henan 464000, China. | 2003 | Applied Mathematics(A Journal of Chinese Universities)2003，18，2： | 0 |
| 12 | Dynamic crosslinked polymeric nano-prodrugs for highly selective synergistic chemotherapy显示文摘To achieve highly selective synergistic chemotherapy attractive for clinical translation,the precise polymeric nano-prodrugs(PPD-NPs)were successfully constructed via the facile crosslinking reaction between p H-sensitive poly(ortho ester)s and reduction-sensitive small molecule synergistic prodrug(Pt(IV)-1).PPD-NPs endowed the defined structure and high drug loading of cisplatin and demethylcantharidin(DMC).Moreover,PPD-NPs exhibited steady long-term storage and circulation via the crosslinked structure,suitable negative potentials and low critical micelle concentration(CMC),improved selective tumour accumulation and cellular internalization via dynamic size transition and surficial amino protonation at tumoural extracellular p H,promoted efficient disintegration and drug release at tumoural intracellular p H/glutathione,and enhanced cytotoxicity via the synergistic effect between cisplatin and DMC with the feed ratio of 1:2,achieving significant tumour suppression while decreasing the side effects.Thus,the dynamic crosslinked polymeric nano-prodrugs exhibit tremendous potential for clinically targeted synergistic cancer therapy. | Shi Wang Yining Song Jingge Ma Xinyang Chen Yuanhui Guan Hui Peng Guoqing Yan Rupei Tang | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员