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| 1 | Bartonella Species Detected in the Plateau Pikas(Ochotona curzoiae) from Qinghai Plateau in China显示文摘Bartonella 种类能感染许多哺乳动物的主人并且在人引起许多疾病,但是在那里有不是在 Ochotonidae 的 Bartonella 感染的报告。这是第一研究在 Qinghai 高原在高原一种短耳野兔检测 Bartonella,提供为对在这个区域的人的 Bartonella 感染的风险评价的基线数据。我们与 18.99% 的积极的率在 Qinghai 的 Binggou 和 Maixiu 区域从 79 只一种短耳野兔获得了 15 Bartonella 紧张。基于基因定序的 Bartonella 柠檬酸盐 synthase (gltA ) 的种系发生的分析,大多数紧张是仔细与 B 有关。taylorii (3/15 ) 和 B。grahamii (12/15 ) 。后者是在人的病原的紧张。我们的结果建议相应预防和控制策略应该在 Qinghai 省被考虑。 | RAO Hua Xiang YU Juan GUO Peng MA Yong Cheng LIU Qi Yong JIAO Ming MA Zhong Wen GE Hua WANG Chun Xiang SONG Xiu Ping SHI Yan LI Dong Mei | 2015 | Biomedical and Environmental Sciences2015，28，9： | 8 |
| 2 | Two new tetrahydronaphthalenes from the stem of Impatiens balsamina L.显示文摘Two new tetrahydronaphthalenes,lα,2α-diol-4α-ethoxy-1,2,3,4-tetrahydronaphthalene(1) and 1a,2a,4β-triol-1,2,3,4- tetrahydronaphthalene(2),were isolated from the stem of Impatiens balsamina L.Their structures were elucidated by various spectroscopic methods. | Chen, Xiu Mei Qian, Shi Hui Feng, Feng | 2010 | Chinese Chemical Letters2010，21，4： | 5 |
| 3 | Malnutrition Increases the Risk of Mortality in Hospitalized Lung Cancer Patients显示文摘Background The Global Leadership Initiative on Malnutrition(GLIM)recently developed a new set of diagnostic criteria for identifying patients with malnutrition.Because the GLIM criteria were only introduced a little over 3 years ago,additional validation and reliability testing are needed in a variety of populations.Methods We performed an observational,multicenter cohort study.From July 2013 to October 2018,lung cancer patients were recruited from the Daping Hospital of Army Medical University and the First Hospital of Jilin University as part of the INSCOC project.Previously-established cut-off values for the calf circumference(CC,male<30 cm,female<29.5 cm)were applied as the reduced muscal mass of phenotypic criteria to establish the GLIM diagnosis.Multivariate Cox regression analyses were performed to analyze the association between the GLIM criteria and survival.Results A total of 1219 patients with lung cancer were studied as subjects.Their age was 58.81±9.92 years old,and 820 were male and 399 were female.According to the GLIM diagnostic criteria using the CC as a muscle mass measurement,303 patients(24.9%)were categorized as malnourished,142 patients(23.1%)in the adult group(18≤age<60)and 161 patients(26.7%)in the older group(age≥60 years).The patients with malnutrition had a higher incidence of anemia than the nourished patients(P=0.012).The QLQ-C30 score and KPS score indicating that the malnourished patients had a consistently worse quality of life compared to the nourished group(all P<0.001).The median survival of the malnutrition group was 42(95%CI:34-50)months,which was much shorter than the 62(95%CI:57-66)months in the nourished group(P<0.001).In the adult group,the median survival decreased from 65(95%CI:55-72)months in nourished group to 34(95%CI:25-48)months in the patients with malnutrition(P<0.001).In the older group,it decreased from 61(95%CI:55-67)months to 48(95%CI:39-59)months(P=0.001).A Cox regression analysis showed that GLIM-diagnosed malnutrition was associated with an increased risk of death among adult group(HR=1.670,95%CI:1.29-2.16),older group(HR=1.332,95%CI:1.05-1.69)and overall(HR=1.453,95%CI:1.22-1.72).Conclusion All of these results demonstrate that GLIM-diagnosed malnutrition is associated with a poorer survival for all lung cancer patients,independent of age. | Fei Fei Chong Liang Yu Yin Jie Liu Na Li Jing Guo Yang Fan Meng Yuan Zhang Ling Zhang Xiu Mei He Hong Mei Zhang Mu Li Shi Wei Li Hong Xia Xu | 2022 | Journal of Nutritional Oncology2022，7，1： | 4 |
| 4 | Utility of Droplet Digital PCR Assay for Quantitative Detection of Norovirus in Shellfish, from Production to Consumption in Guangxi, China显示文摘Objective Shellfish are recognized as important vehicles of norovirus-associated gastroenteritis. The present study aimed to monitor norovirus contamination in oysters along the farm-to-fork continuum in Guangxi, a major oyster production area in Southwestern China. Methods Oyster samples were collected monthly from farms, markets, and restaurants, from January to December 2016. Norovirus was detected and quantified by one-step reverse transcription-droplet digital polymerase chain reaction(RT-ddPCR). Results A total of 480 oyster samples were collected and tested for norovirus genogroups I and II. Norovirus was detected in 20.7% of samples, with genogroup II predominating. No significant difference was observed in norovirus prevalence among different sampling sites. The norovirus levels varied widely, with a geometric mean of 19,300 copies/g in digestive glands. Both norovirus prevalence and viral loads showed obvious seasonality, with a strong winter bias. Conclusion This study provides a systematic analysis of norovirus contamination ‘from the farm to the fork' in Guangxi. RT-ddPCR can be a useful tool for detection and quantification of low amounts of norovirus in the presence of inhibitors found particularly in foodstuffs. This approach will contribute to the development of strategies for controlling and reducing the risk of human illness resulting from shellfish consumption. | TAN Dong Mei LYU Su Ling LIU Wei ZENG Xian Ying LAN Lan QU Cong ZHUGE Shi Yang ZHONG Yan Xu XIE Yi Hong LI Xiu Gui | 2018 | Biomedical and Environmental Sciences2018，31，10： | 4 |
| 5 | Combination Use of PFGE and Drug-resistant Analysis in the Epidemiological Investigation of Listeria Monocytogenes显示文摘Listeria monocytogenes is the pathogen of listeriosis and it causes severe infections like septicemia,encephalitis,and meningitis,especially in immunocompromised individuals,newborns,and pregnant women.Its wide distribution in the environment and ability to survive or even | LV Jun ZHENG Xiang Mei CHENG Shi Xiu ZHENG Hua Ying ZENG Ying Chun | 2013 | Biomedical and Environmental Sciences2013，26，4： | 2 |
| 6 | Comparison of long non?coding RNAs, microRNAs and messenger RNAs involvedin initiation and progression of esophageal squamous cell carcinoma显示文摘 | Su?Qing Li Feng Li Yun Xiao Chun?Mei Wang Lei Tuo Jing Hu Xiao?Bin Yang Jin?Song Wang Wei?Hong Shi Xia Li Xiu?Feng Cao | 2014 | Molecular Medicine Reports2014，，2： | 1 |
| 7 | Distribution of Microbiota in Fine Particulate Matter Particles in Guangzhou, China显示文摘Objective High PM2.5 concentration is the main feature of increasing haze in developing states,but information on its microbial composition remains very limited.This study aimed to determine the composition of microbiota in PM2.5 in Guangzhou,a city located in the tropics in China.Methods In Guangzhou,from March 5th to 10th,2016,PM2.5 was collected in middle volume air samplers for 23 h daily.The 16 S rDNA V4 region of the PM2.5 sample extracted DNA was investigated using high-throughput sequence.Results Among the Guangzhou samples,Proteobacteria,Bacteroidetes,Firmicutes,Cyanobacteria,and Actinobacteria were the dominant microbiota accounting for more than 90%of the total microbiota,and Stenotrophomonas was the dominant gram-negative bacteria,accounting for 21.30%–23.57%.We examined the difference in bacterial distribution of PM2.5 between Beijing and Guangzhou at the genus level;Stenotrophomonas was found in both studies,but Escherichia was only detected in Guangzhou.Conclusion In conclusion,the diversity and specificity of microbial components in Guangzhou PM2.5 were studied,which may provide a basis for future pathogenicity research in the tropics. | DONG Shi Rui HAN Ya Jing WU Jing ZENG Cheng Li ZHU Ke Hui CHEN Xiao Jing LIU Yu Mei ZOU Xiao Qian ZHENG Shao Ling WEN Zi Hao LIU Dan Dan WANG Yao HUANG Xiu Xia DU Xiu Ben HAO Jian Lei WANG Huan Yu GUO Shu JING Chun Xia YANG Guang | 2020 | Biomedical and Environmental Sciences2020，33，5： | 1 |
| 8 | The Synthesis of 4-Arylcarbonyl-3-methoxycarbonyl-2-phenylfurans by Friedel-Crafts Acylation Reactions显示文摘Keto esters 8, 4-arylcarbonyl-3-methoxycarbonyl potential precursors of the synthesis of furofuran lignans, were obtained from dimethyl 2-phenylfuran- 3,4dicarboxylate 2. Diester 2 was selectively hydrolyzed to monoacid 6 followed by converting to its acid chloride 7. Friedel-Crafts acylation reactions of 7 with aromatic compounds afforded keto esters 8. The geometric structures of 8 and its precursors were elucidated and verilied by NMR spectra. | Shrong Shi LIN Jun Hua YU Jian Mei WANG Bo YANG Xiu Lin YE (Department of Chemistry. Peking University, Beijing 100871) | 2000 | Chinese Chemical Letters2000，11，1： | 0 |
| 9 | Determination of Trace Mercury by Catalytic Solid Substrate-room Temperature Phosphorimetry显示文摘A new highly sensitive method (detection limit: 4.1 ag spot-1, sample volume: 0.4 μL spot-1) for the determination of trace Hg2+ by catalytic solid substrate-room temperature phosphorimetry has been established in this paper. This method has been successfully applied to determine trace Hg2+ in water. | Jia Ming LIU Yun Xiong WU Shao Xian LIN Fei Ming LI Xiu Mei SHI Zhong Bin SHI Guo Hui ZHU Zhi Ming LI Xiao Mei HUANG | 2006 | Chinese Chemical Letters2006，17，12： | 0 |
| 10 | Determination of trace calcium by solid substrate-room temperature phosphorimetry显示文摘A new method for the determination of trace calcium by solid substrate-room temperature phosphorimetry is established. It is based on the fact that chromeazurols azurol S-phenanthroline-NaCMC (CAS-phen-NaCMC) system can emit strong and stable room temperature phosphorescence (RTF) on the solid substrate in the filter paper. Ca2+ and phenanthroline can form complex ion Ca(phen)32+, which will form complex [Ca(phen)3(CAS)2] with CAS. In the result, the number of CAS molecules in each spot increased, causing sharp increase of the RTP signal of the CAS-phen-NaCMC system. | Jia Ming Liu Tian Long Yang Xiao Mei Huang Xiu Mei Shi Zhong Bin Shi Hong Wu Guo Hui Zhu Zhi Ming Li Cui Lian Chen | 2007 | Chinese Chemical Letters2007，18，2： | 0 |
| 11 | Traditional Chinese medicine nursing protocols for COVID-19显示文摘In order to facilitate nurses to understand the key points of COVID‑19’s common syndromes,master the key points of nursing with syndrome differentiation,use the advantages of traditional Chinese medicine(TCM)nursing characteristics,standardize TCM nursing behavior,and improve the TCM nursing effect,through the search of relevant information,combined with the clinical practice experience of more than 1 month of front‑line anti‑epidemic nursing staff,the TCM nursing protocols for COVID‑19(draft)were formed.After four rounds of expert consultation and discussion,and 15 times of collation and revision,the final version of TCM nursing protocols for COVID‑19 was formed.The TCM nursing protocols for COVID‑19 include the following five parts:key points of common syndromes,nursing for common symptoms/syndromes,TCM special nursing,healthy guidance,and difficulties in nursing;it is scientific and practical,and can provide clinical guidance for nursing of patients with COVID‑19. | Mei‑Zhen LIN Qiao‑Mei WU Yu LIU Zhong‑De ZHANG Gang‑Yi PENG Chang‑Xiu WAN Xiao‑Pan WANG Ying‑Rui MA Ping XIONG Hui‑Chao CHEN Qiu‑Ying DENG Li‑Li DENG Ding‑Rong QIU Lin WEI Jiu‑Hong YOU Yang‑Chen LIU Guang‑Qing ZHANG Li‑Xia KOU Ming‑Ming XU Yu‑Mei CHEN Yin‑Qin ZHONG Xiao‑Qin LU Han‑Jiao LIU Jin ZHOU Hong YE Xiao‑Zhen GONG Shi‑Miao LUO Xi‑Yan HU | 2020 | Journal of Integrative Nursing2020，2，2： | 0 |
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