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| 1 | E-cadherin gene C-160A promoter polymorphism and risk of non-cardia gastric cancer in a Chinese population显示文摘AIM: To test the hypothesis that E-cadherin gene (CDH1)C-160A promoter variant genotype is associated with an increased risk for developing gastric cancer.METHODS: In this population-based case-control study of gastric cancer in Jiangsu Province, China, we performed polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) to genotype the C-160A polymorphism of CDH1 promoter in 206 non-cardia gastriccancer patients and 261 age- and sex-matched but unrelated cancer-free controls.RESULTS: The frequencies of genotypes CC, CA and AA were 57.8%, 36.4% and 5.8% in gasfric cancer cases,respectively, and 58.2%, 34.9% and 6.9% in controls respectively. The distributions of CDH1 genotypes were not significantly different between gastric cancer cases and controls (P = 0.87 for genotype frequency and P = 0.92for allele frequency). Compared with the CC genotype, the CA and AA genotypes were not associated with an increased risk for non-cardia gastric cancer (adjusted odds ratios (OR)= 1.15, and 95% confidence interval (95% CI) = 0.78-1.72for CA genotype, and OR = 0.90 and 95% CI = 0.42-2.01for AA genotype).CONCLUSION: E-cadherin gene C-160A promoter polymorphism may not play a major role in the etiology of non-cardia gastric cancer in Chinese population. | YanLu Yao-Chuxu JingShen Rong-BinYu Ju-YinNiu Jian-TaoGuo XuHu Hong-BingShen | 2005 | World Journal of Gastroenterology2005，11，1： | 8 |
| 2 | 罗布麻叶研究现状及设想显示文摘 | XUHu(许虎) LIUXun-hong(刘训红) WANGMei(王媚) etal | | 中国现代应用药学0，，： | 1 |
| 3 | Preparation and properties of ZnO: Ga films prepared by RF magnetron sputtering at low temperature 显示文摘 | Xuhu Y Jin M Feng J | 2005 | Appl Surf Sci2005，239，2： | 1 |
| 4 | Up-regulated microRNA-146a negatively modulate Helicobacter pylori -induced inflammatory response in human gastric epithelial cells显示文摘 | Zhen Liu Bin Xiao Bin Tang Bosheng Li Na Li Endong Zhu Gang Guo Jiang Gu Yuan Zhuang Xiaofei Liu Honglei Ding Xiaoyan Zhao Hong Guo Xuhu Mao Quanming Zou | 2010 | Microbes and Infection2010，，11： | 1 |
| 5 | Effect of quenching temperature on microstructures and tensile properties of PM Ti-23A1-17Nb显示文摘 | Lang Zebao Zhang Xuhu Wang Liang | 2011 | Advanced Materials Research2011，279，： | 1 |
| 6 | Thickness dependence of properties of ZnO : Ga films deposited by rf magnetron sputtering 显示文摘 | Yu Xuhu Ma Jin Ji Feng | 2005 | Applied Surface Science2005，245，14： | 1 |
| 7 | Thickness dependence of properties of ZnO : Ga films deposited by rf magnetron sputtering显示文摘 | Yu Xuhu Ma Jiu Ji Feng | 2005 | Appl Surf Sci2005，245，310： | 1 |
| 8 | Specific detection and effective inhibition of a single bacterial species in situ using peptide mineralized Au cluster probes显示文摘Increasingly serious microbial infections call for the development of new simpler methods for the precise diagnosis and specific inhibition of such pathogens. In this work, a peptide mineralized Au cluster probe was applied as a new simplified strategy to both recognize and inhibit a single bacteria species of Staphylococcus aureus(S. aureus) simultaneously. The probes are composed of peptides and Au clusters. Moreover, the peptides specifically target S. aureus cells and the Au clusters provide fluorescent imaging and have an antibacterial effect. These new probes enable the simultaneous specific detection and effective destruction S. aureus cells in situ. | Xiangchun Zhang Li Liu Ru Liu Jing Wang Xuhu Hu Qing Yuan Juanjuan Guo Gengmei Xing Yuliang Zhao Xueyun Gao | 2018 | Science China Chemistry2018，61，5： | 0 |
| 9 | Deformation control criterion of shield tunnel under lateral relaxation of soft soil显示文摘Metro shield tunnels under the lateral relaxation of soil(LRS)are susceptible to significant lateral deformations,which jeopardizes the structural safety and waterproofing.However,deformation control standards for such situations have not been clearly defined.Therefore,based on a specific case,a model test is conducted to realize the LRS of a shield tunnel in a sandy stratum to reveal its effect on segment liners.Subsequently,a deformation control criterion is established.The LRS is simulated by linearly reducing the loads applied to the lateral sides of the segment structure.During lateral unloading,the lateral earth pressure coefficient on the segment decreases almost exponentially,and the structural deformation is characterized by horizontal expansion at the arch haunches and vertical shrinkage at the arch vault and arch bottom.Based on the mechanical pattern of the segment structure and the acoustic emission,the deformation response of a segment can be classified into three stages:elastic and quasi-elastic,damage,and rapid deformation development.For a shield tunnel with a diameter of approximately 6 m and under the lateral relaxation of sandy soil,when the ellipticity of the segment is less than 2.71%,reinforcement measures are not required.However,the segment deformation must be controlled when the ellipticity is 2.71%to 3.12%;in this regard,an ellipticity of 3%can be used as a benchmark in similar engineering projects. | Shimin WANG Xiaoyu PENG Hang ZHOU Xuhu HE Anqi ZHOU Bing CHEN | 2023 | Frontiers of Structural and Civil Engineering2023，17，5： | 0 |
| 10 | Methylenetetrahydrofolate Reductase Genotypes, Dietary Habits and Susceptibility to Stomach Cancer显示文摘OBJECTIVE To study the relation among methylenetetrahydrofolate reductase (MTHFR) C677T genotypes, dietary habits and the risk of stomach cancer (SC).METHODS A case-control study was conducted with 107 cases of SC and 200 population-based controls in Chuzhou district, Huaian, Jiangsu province, China. The epidemiological data were collected, and DNA of peripheral blood leukocytes was obtained from all of the subjects..MTHFR genotypes were detected by PCR-RFLP. RESULTS (1) The prevalence of the MTHFR C/T or T/T genotypes was found to be significantly different between controls (68.5%) and SC cases (79.4%,P=0.0416), the increased risk had an adjusted OR of 1.79 (95%C1:1.01-3.19). (2) Among subjects who had a low intake of garlic or Chinese onion, MTHFR C/T or T/T genotypes significantly increased the risk of developing SC. Among non-tea drinkers or among subjects who had a frequent intakeof meat, the carriers of the MTHFR C/T or T/T genotypes had a higher risk of SC than individuals with the C/C type MTHFR. CONCLUSION The polymorphism of MTHFR C677T was associated with increased risk of developing SC, and that individuals with differing genotypes may have different susceptibilities to SC, based on their exposure level to environmental factors. | ChangmingGao TakezakiToshiro JianzhongWu JianhuoDing YantingLiu SupingLi PingSu XuHu TianliongXu HamajimaNobuyuki TajimaKazuo | 2004 | Chinese Journal of Clinical Oncology2004，1，3： | 0 |
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