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| 1 | N6-Methyladenine DNA Methylation in Japonica and Indica Rice Genomes and Its Association with Gene Expression,Plant Development, and Stress Responses显示文摘N6-Methyladenine (6mA)DNA methylation has recently been implicated as a potential new epigenetic marker in eukaryotes,including the dioot modelArabidopsis thaliana.However,the conservation and divergence of 6mA distribution patterns and functions in plants remain elusive.Here we report high-quality 6mA methylomes at single-nucleotide resolution in rice based on substantially improved genome sequences of two rice cultivars,Nipponbare (Nip;Japonica)and 93-11 (Indica).Analysis of 6mA genomic distribution and its association with transcription suggest that 6mA distribution and function is rather conserved between rice and Arabidopsis.We found that 6mA levels are positively correlated with the expression of key stressrelated genes,which may be responsible for the difference in stress tolerance between Nip and 93-11. Moreover,we showed that mutations in DDM1 cause defects in plant growth and decreased 6mA level. Our results reveal that 6mA is a conserved DNA modification that is positively associated with gene expression and contributes to key agronomic traits in plants. | Qian Zhang Zhe Liang Xuean Cui Changmian Ji Yun Li Pingxian Zhang Jingrong Liu Adeel Riaz Pu Yao Min Liu Yunpeng Wang Tiegang Lu Hao Yu Donglei Yang Hongkun Zheng Xiaofeng Gu | 2018 | Molecular Plant2018，11，12： | 18 |
| 2 | Improved Brassica rapa reference genome by single-molecule sequencing and chromosome conformation capture technologies显示文摘Brassica rapa comprises several important cultivated vegetables and oil crops.Current reference genome assemblies of Brassica rapa are quite fragmented and not highly contiguous,thereby limiting extensive genetic and genomic analyses.Here,we report an improved assembly of the B.rapa genome(v3.0)using single-molecule sequencing,optical mapping,and chromosome conformation capture technologies(Hi-C).Relative to the previous reference genomes,our assembly features a contig N50 size of 1.45 Mb,representing a~30-fold improvement.We also identified a new event that occurred in the B.rapa genome~1.2 million years ago,when a long terminal repeat retrotransposon(LTR-RT)expanded.Further analysis refined the relationship of genome blocks and accurately located the centromeres in the B.rapa genome.The B.rapa genome v3.0 will serve as an important community resource for future genetic and genomic studies in B.rapa.This resource will facilitate breeding efforts in B.rapa,as well as comparative genomic analysis with other Brassica species. | Lei Zhang Xu Cai Jian Wu Min Liu Stefan Grob Feng Cheng Jianli Liang Chengcheng Cai Zhiyuan Liu Bo Liu Fan Wang Song Li Fuyan Liu Xuming Li Lin Cheng Wencai Yang Mai-he Li Ueli Grossniklaus Hongkun Zheng Xiaowu Wang | 2018 | Horticulture Research2018，5，1： | 10 |
| 3 | Effect of N fertilization rate on soil alkalihydrolyzable N, subtending leaf N concentration,fiber yield, and quality of cotton显示文摘Soil alkali-hydrolyzable nitrogen, which is sensitive to N fertilization rate, is one of the indicators of soil nitrogen supplying capacity. Two field experiments were conducted in Dongtai(120°19″ E, 32°52″ N), Jiangsu, China in 2009 and Dafeng(120°28″ E, 33°12″ N), Jiangsu province, China in 2010. Six nitrogen rates(0, 150, 300, 375, 450, and 600 kg ha^(-1)) were used to study the effect of N fertilization rate on soil alkali-hydrolyzable nitrogen content(SAHNC), subtending leaf nitrogen concentration(SLNC), yield, and fiber quality. In both Dongtai and Dafeng experiment station, the highest yield(1709 kg ha^(-1)), best quality(fiber length 30.6 mm, fiber strength 31.6 c N tex^(-1), micronaire 4.82), and highest N agronomic efficiency(2.03 kg kg^(-1)) were achieved at the nitrogen fertilization rate of 375 kg ha^(-1). The dynamics of SAHNC and SLNC could be simulated with a cubic and an exponential function,respectively. The changes in SAHNC were consistent with the changes in SLNC. Optimal average rate(0.276 mg day^(-1)) and duration(51.8 days) of SAHNC rapid decline were similar to the values obtained at the nitrogen rate of 375 kg ha^(-1)at which cotton showed highest fiber yield, quality, and N agronomic efficiency. Thus, the levels and strategies of nitrogen fertilization can affect SAHNC dynamics. The N fertilization rate that optimizes soil alkali-hydrolyzable nitrogen content would optimize the subtending leaf nitrogen concentration and thereby increase the yield and quality of the cotton fiber. | Binglin Chen Hongkun Yang Weichao Song Chunyu Liu Jiao Xu Wenqing Zhao Zhiguo Zhou | 2016 | The Crop Journal2016，4，4： | 8 |
| 4 | Effects of mepiquat chloride on yield and main properties of cottonseed under different plant densities显示文摘Background:Cottonseed oil and protein content as well as germination traits are major indicators of seed quality.However,the responses of these indicators to plant density and mepiquat chloride(MC)are still uncertain.To investigate plant density and MC effects on cotto nseed yield and main quality parameters,we con ducted a twoyear field experiment including four plant densities(1.35,2.55,3.75 and 4.95 plants·m^-2)and two closes of MC(0 and 135g·hm^-2)in Dafeng,Jiangsu Province,in 2013 and 2014.Results:The application of MC reduced plant height,fruit branch length and fruiting branch number under different plant densities,resulting in a lower and more compact plant canopy.Cottonseed yield showed a nonlinear increase as plant density increasing and achieved the highest value at 3.75 plants·m^-2,regardless of MC application.No significant interactio ns were found between plant density and MC for cotton seed yield and quality parameters.The 100-seed weight,cottonseed oil content and vigor index significantly decreased as plant density increased,while these parameters significantly increased with MC applying under different plant densities.Seed vigor index was positively correlated with 100-seed weight and seed oil con tent across different plant densities and MC treatments.Conclusions:Thus,application of MC could realize a win-win situation between cottonseed yield and main quality parameters under various densities;and plant density of 3.75 plants·m^-2 combined with 135 g·hm^-2 of MC applying is optimal for high cottonseed yield and quality in this cotton production area. | ZHAO Wenqing YAN Qiang YANG Hongkun YANG Xiaoni WANG Leran CHEN Binglin MENG Yali ZHOU Zhiguo | 2019 | Journal of Cotton Research2019，2，2： | 3 |
| 5 | Agronomic and physiological traits associated with genetic improvement of phosphorus use efficiency of wheat grown in a purple lithomorphic soil显示文摘Developing wheat that acquires and uses phosphorus(P)more efficiently is a promising and low-cost solution for increasing grain yield and reducing P-related environmental impacts.The present study identified agronomic and physiological traits that contribute to genetic variation in the P acquisition,remobilization,and utilization efficiency of 11 wheat cultivars from southwest China grown in P-deficient purple lithomorphic soil(Olsen P=4.7)with balanced(75 kg P ha^(−1))and excess P(120 kg P ha^(−1))supplies.On average,soil P deficiency(–P)reduced root P uptake(17.0%–60.8%),P remobilization(33.9%–52.8%),dry mass yield(11.5%–39.2%),and grain yield(17.7%–54.4%).Balanced P(+P)increased grain yield via increased plant biomass rather than increased HI.–P increased phosphorus uptake efficiency(PUpE,4.5-fold),phosphorus utilization efficiency(PUtE,1.25-fold),and phosphorus use efficiency(PUE,5.4-fold)compared with those under+P,and PUtE explained most(58.1%–60.8%)of the genetic variation in PUE under both–P and+P.The high root P uptake of P-efficient cultivars under–P was regulated by root surface area and root length density in the 0–10 cm soil layer but not in the 10–20 and 20–40 cm soil layers,suggesting that a topsoil foraging strategy is a more economical approach than deeper root exploration for increasing P uptake.Root P uptake before anthesis and P remobilization after anthesis were critical for increasing the PUtE of wheat,given that P-efficient cultivars showed higher Pn(net photosynthetic rate)and sucrose levels than P-inefficient cultivars.Pn reduction by–P resulted from decreased Gs and Ci,and high evapotranspiration under+P increased shoot P%by increasing root P uptake.Genetic variation in the source-to-sink ratio was observed in consequence of a+P-induced allometric increase in sucrose in leaves and kernels.Owing to these beneficial effects,+P increased the kernel N and P yields of the 11 cultivars by 9.9%–52.4%and 12.3%–48.8%,respectively.The findings of this study could help improve wheat in future breeding efforts and P management by identifying desirable Pefficient phenotypes in P-deficient farming systems. | Hongkun Yang Renhua Chen Yufeng Chen Han Li Ting Wei Wei Xie Gaoqiong Fan | 2022 | The Crop Journal2022，10，4： | 2 |
| 6 | Nonlinear optical absorption properties of InP nanowires and applications as a saturable absorber显示文摘Indium phosphide(InP)nanowires(NWs)have attracted significant attention due to their exotic properties that are different from the bulk counterparts,and have been widely used for light generation,amplification,detection,modulation,and switching,etc.Here,high-quality InP NWs were directly grown on a quartz substrate by the Au-nanoparticle assisted vapor-liquid-solid method.We thoroughly studied their nonlinear optical absorption properties at 1.06μm by the open-aperture Z-scan method.Interestingly,a transition phenomenon from satu-rable absorption(SA)to reverse saturable absorption(RSA)was observed with the increase of the incident laser intensity.In the analysis,we found that the effective nonlinear absorption cofficient(βeff-10^2 cm/MW)under the SA process was 3 orders of magnitude larger than that during the RSA processes.Furthermore,the SA proper-ties of InP NWs were experimentally verified by using them as a saturable absorber for a passively Q-switched Nd:YVO4 solid-state laser at 1.06μm,where the shortest pulse width of 462 ns and largest single pulse energy of 1.32μJ were obtained.Moreover,the ultrafast carrier relaxation dynamics were basically studied,and the intraband and inter-band ultrafast carrier relaxation times of 8.1 and 63.8 ps,respectively,were measured by a degenerate pump-probe method with the probe laser of 800 nm.These results well demonstrate the nonlinear optical absorption properties,which show the excellent light manipulating capabilities of InP NWs and pave a way for their applications in ultrafast nanophotonic devices. | JUNTING LIU HONGKUN NIE BINGZHENG YAN KEJIAN YANG HE YANG VLADISLAV KHAYRUDINOV HARRI LIPSANEN BAITAO ZHANG JINGLIANG HE | 2020 | Photonics Research2020，8，6： | 2 |
| 7 | Straw mulch-based no-tillage improves tillering capability of dryland wheat by reducing asymmetric competition between main stem and tillers显示文摘The moisture-conserving effect of straw mulch-based no-tillage(SMNT)is expected to increase fertile spikes and grain yield in environments with rainfall less than 200 mm.However,the mechanisms under-lying the positive effect of SMNT on wheat tillering are not fully elucidated.A split-plot experiment was designed to investigate the combined effects of SMNT and cultivars on tillering of dryland wheat grown under both dry and favorable climates.Application of SMNT to a cultivar with 1-2 tillers exploited both tillering and kernel-number plasticity,increasing the mean grain yield by 20.5%.This increase was attrib-uted primarily to an increased first-tiller emergence rate resulting from increased N uptake,leaf N con-tent,and N remobilization from tillers to their grain.The second and third tillers,as transient sinks,contributed to the tiller survival rate,which depends on tiller leaf number.The increased total N uptake by SMNT also increased the dry mass yield of tillers and the C:N ratio,reducing the asymmetric compe-tition between main stem and tillers.Owing to these beneficial effects,reduced mitogen-activated pro-tein kinase(MAPK)and abscisic acid signals were observed under SMNT,whereas indole-3-acetic acid(IAA)signals and genes involved in DNA replication and mismatch repair were increased.These signals activated three critical transcription factors(the calmodulin-binding transcription activator,GRAS domain,and cysteine-2/histidine-2 family)and further increased rapid drought response and tiller main-tenance after stem extension.Phenylpropanoid biosynthesis,sphingolipid biosynthesis,and galactose metabolism were most relevant to increased tillering under SMNT because of their critical role in drought response and lignin biosynthesis.Our results suggest that straw mulch-based no-tillage activates rapid drought response and improved wheat tillering by coordinating root N uptake,N remobilization,and asymmetric competition between main stem and tillers. | Hongkun Yang Yun Xiao Peng He Dailong Ai Qiaosheng Zou Jian Hu Qiong Liu Xiulan Huang Ting Zheng Gaoqiong Fan | 2022 | The Crop Journal2022，10，3： | 2 |
| 8 | Author Correction:Improved Brassica rapa reference genome by single-molecule sequencing and chromosome conformation capture technologies显示文摘Since the publication of this article,the authors have noticed that the total gene models(45,985),tandem arrays(2077),tandem genes(4963),redundancy removed(43,099),syntenic genes(39,858),nonsyntenic genes(3241),genes on chromosomes(45,411),genes on scaffolds(574)of B.rapa reference genome v3.0 were mistaken in the article. | Lei Zhang Xu Cai Jian Wu Min Liu Stefan Grob Feng Cheng Jianli Liang Chengcheng Cai Zhiyuan Liu Bo Liu Fan Wang Song Li Fuyan Liu Xuming Li Lin Cheng Wencai Yang Mai-he Li Ueli Grossniklaus Hongkun Zheng Xiaowu Wang | 2019 | Horticulture Research2019，6，1： | 2 |
| 9 | Real-time verification of network properties using atomic predicates显示文摘 | Yang Hongkun Lam S S | 2015 | IEEE/ACM Trans on Networking2015，24，2： | 1 |
| 10 | Synthesis,Characterization and Application of Poly(lactic-co-glycolic acid)with a Mass Ratio of Lactic to Glycolic Segments of 52/48显示文摘Poly(lactic-co-glycolic acid)(PLGA)is one of the most representative degradable copolymers and promising drug carriers.In the current paper,the PLGAs with a lactic acid/glycolic acid(LA/GA)molar ratio of 52/48 and various molecular weights were prepared by a melting method.The molecular weight,molecular weight distribution,and thermal stability were determined by 1H NMR and thermogravimetric analysis methods.The results demonstrated that PLGAs with the fixed LA/GA molar ratio(52/48),different molecular weights,and narrow molecular weight distribution could be obtained by solely altering the reaction time.The PLGA films were prepared,and their properties including micro-structure,mechanical property,in-vitro cytotoxicity,and biodegradability were characterized.In combination with the homogeneous microstructures and mechanical properties,the drug-loading and releasing properties of PLGA3.2 films were investigated.The results show that PLGA3.2 film with an LA/GA molar ratio of 52/48 is a promising curcumin carrier. | QIN Chang DONG Jing XIE Beibei WANG Hongkun ZHANG Na ZHAO Chunhua QIAO Congde LIU Mingxia YANG Xiaodeng LI Tianduo | 2023 | Chemical Research in Chinese Universities2023，39，2： | 1 |
| 11 | βII‐Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin显示文摘 | Xiuling Zhi Ling Lin Shaoxian Yang Krithika Bhuvaneshwar Hongkun Wang Yuriy Gusev Mi‐Hye Lee Bhaskar Kallakury Narayan Shivapurkar Katherine Cahn Xuefei Tian John L. Marshall Stephen W. Byers Aiwu R. He | 2015 | Hepatology2015，，2： | 1 |
| 12 | Evolutionary Transients in the Rice Transcriptome显示文摘In the canonical version of evolution by gene duplication, one copy is kept unaltered while the other is free to evolve. This process of evolutionary experimentation can persist for millions of years. Since it is so short lived in comparison to the lifetime of the core genes that make up the majority of most genomes, a substantial fraction of the genome and the transcriptome may-in principle-be attributable to what we will refer to as 'evolutionary transients', referring here to both the process and the genes that have gone or are undergoing this process. Using the rice gene set as a test case, we argue that this phenomenon goes a long way towards explaining why there are so many more rice genes than Arabidopsis genes, and why most excess rice genes show low similarity to eudicots. | Jun Wang Jianguo Zhang Ruiqiang Li Hongkun Zheng Jun Li Yong Zhang Heng Li Peixiang Ni Songgang Li Shengting Li Jingqiang Wang Dongyuan Liu Jason McDermott Ram Samudrala Siqi Liu Jian Wang Huanming Yang Jun Yu Gane Ka-Shu Wong | 2010 | Genomics, Proteomics & Bioinformatics2010，8，4： | 0 |
| 13 | Novel boron-and sulfur-doped polycyclic aromatic hydrocarbon as multiple resonance emitter for ultrapure blue thermally activated delayed fluorescence polymers显示文摘Boron(B)-and sulfur(S)-doped polycyclic aromatic hydrocarbons(PAHs)are developed as a novel kind of multiple resonance emitters for ultrapure blue thermally activated delayed fluorescence(TADF)polymers with narrowband electroluminescence.The combination of electron-deficient B atom and electron-rich S atom in PAH can form an intramolecular push-pull electronic system in a rigid aromatic framework,leading to reduced singlet-triplet energy splitting and limited structure relaxation of excited states.The critical roles of S atom in determining emission properties with respect to the oxygen analogues are in two aspects:(i)reducing energy bandgap to shift emission from human-eye-insensitive ultraviolet zone to blue region,and(ii)promoting reverse intersystem crossing process by heavy-atom effect to activate TADF effect.The resulting polymer containing B,S-doped PAH as emitter and acridan as host exhibits efficient blue electroluminescence at 458 nm with small full-width at halfmaximum of 31 nm,representing the first example for ultrapure TADF polymer with narrowband electroluminescence. | Fan Chen Lei Zhao Xingdong Wang Qingqing Yang Weili Li Hongkun Tian Shiyang Shao Lixiang Wang Xiabin Jing Fosong Wang | 2021 | Science China Chemistry2021，64，4： | 0 |
| 14 | Expert consensus on difficulty assessment of endodontic therapy显示文摘Endodontic diseases are a kind of chronic infectious oral disease. Common endodontic treatment concepts are based on the removal of inflamed or necrotic pulp tissue and the replacement by gutta-percha. However, it is very essential for endodontic treatment to debride the root canal system and prevent the root canal system from bacterial reinfection after root canal therapy(RCT). Recent research, encompassing bacterial etiology and advanced imaging techniques, contributes to our understanding of the root canal system’s anatomy intricacies and the technique sensitivity of RCT. Success in RCT hinges on factors like patients, infection severity, root canal anatomy, and treatment techniques. Therefore, improving disease management is a key issue to combat endodontic diseases and cure periapical lesions. The clinical difficulty assessment system of RCT is established based on patient conditions, tooth conditions, root canal configuration, and root canal needing retreatment, and emphasizes pre-treatment risk assessment for optimal outcomes. The findings suggest that the presence of risk factors may correlate with the challenge of achieving the high standard required for RCT. These insights contribute not only to improve education but also aid practitioners in treatment planning and referral decision-making within the field of endodontics. | Dingming Huang Xiaoyan Wang Jingping Liang Junqi Ling Zhuan Bian Qing Yu Benxiang Hou Xinmei Chen Jiyao Li Ling Ye Lei Cheng Xin Xu Tao Hu Hongkun Wu Bin Guo Qin Su Zhi Chen Lihong Qiu Wenxia Chen Xi Wei Zhengwei Huang Jinhua Yu Zhengmei Lin Qi Zhang Deqin Yang Jin Zhao Shuang Pan Jian Yang Jiayuan Wu Yihuai Pan Xiaoli Xie Shuli Deng Xiaojing Huang Lan Zhang Lin Yue Xuedong Zhou | 2024 | International Journal of Oral Science2024，16，1： | 0 |
| 15 | A bifunctional vinyl-sulfonium tethered peptide induced by thio-Michael-type addition reaction显示文摘The modification and functionalization of peptides is of great significance in modern biotechnology and drug development. Here we report a highly reactive Michael-type warhead for the covalently modification of cysteine on peptide and protein. By installing a vinyl group onto a methionine residue of peptide,the produced vinyl sulfonium can be efficiently nucleophilic added by appropriate cysteine residue of this peptide, and thus yield a cyclized peptide. This peptide cyclization strategy was proven to exhibit improved cell penetration and good stability. Moreover, a peptide ligand bearing vinyl sulfonium could covalently bind to the cysteine in the target protein, indicating the potential of vinyl sulfonium as a novel warhead for developing covalent peptide inhibitor. | Hongkun Xu Xuan Qin Yaping Zhang Chuan Wan Rui Wang Zhanfeng Hou Xiaofeng Ding Hailing Chen Ziyuan Zhou Yang Li Chenshan Lian Feng Yin Zigang Li | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
| 16 | Detecting positive darwinian selection in brain-expressed genes during human evolution显示文摘To understand the genetic basis that underlies the phenotypic divergence between human and non- human primates, we screened a total of 7176 protein-coding genes expressed in the human brain and compared them with the chimpanzee orthologs to identify genes that show evidence of rapid evolution in the human lineage. Our results showed that the nonsynonymous/synonymous substitution (Ka/Ks) ratio for genes expressed in the brain of human and chimpanzee is 0.3854, suggesting that the brain-expressed genes are under functional constraint. The X-linked human brain-expressed genes evolved more rapidly than autosomal ones. We further dissected the molecular evolutionary patterns of 34 candidate genes by sequencing representative primate species to identify lineage-specific adaptive evolution. Fifteen out of the 34 candidate genes showed evidence of positive Darwinian selection in human and/or chimpanzee lineages. These genes are predicted to play diverse functional roles in em- bryonic development, spermatogenesis and male fertility, signal transduction, sensory nociception, and neural function. This study together with others demonstrated the usefulness and power of phy- logenetic comparison of multiple closely related species in detecting lineage-specific adaptive evolu- tion, and the identification of the positively selected brain-expressed genes may add new knowledge to the understanding of molecular mechanism of human origin. | QI XueBin YANG Su ZHENG HongKun WANG YinQiu LIAO ChengHong LIU Ying CHEN XiaoHua SHI Hong YU xiaoJing Alice A. LIN Luca L. CAVALLI-SFORZA WANG Jun SU Bing | 2007 | Chinese Science Bulletin2007，52，3： | 0 |
| 17 | Preparation of hysteresis-free flexible perovskite solar cells via interfacial modification显示文摘In recent years, flexible perovskite solar cells have received extensive attention and rapid development due to their advantages of lightweight, portability, wearability and applications in near-space. However,due to the limitations of their preparation process and other factors, high-efficiency and large-area flexible perovskite solar cells still have a lot of room for development. In our work, a flexible perovskite solar cell(PEN/ITO/Sn O2/KCl/Cs0.05(MA0.17 FA0.83)0.95 Pb(I0.83 Br0.17)3/spiro/Au) was prepared using a low temperature(no higher than 100°C) solution process, and the device with the highest efficiency of 16.16%was obtained by adjusting the concentration of the KCl modified layer. Meanwhile, the efficiency of the large area(1 cm2) flexible solar cell was higher than 13%. At the same time, the passivation of the KCl interface modification layer inhibits the formation of the defect states, which reduced the surface recombination of the perovskite and improved the carrier transport performance, and the hysteresis effect of the device was also reduced accordingly. | Xiaofang Ye Hongkun Cai Jian Su Jingtao Yang Jian Ni Juan Li Jianjun Zhang | 2021 | Journal of Materials Science & Technology2021，，2： | 0 |
| 18 | Comparative Genomics Reveals Evolutionary Drivers of Sessile Life and Left-right Shell Asymmetry in Bivalves显示文摘Bivalves are species-rich mollusks with prominent protective roles in coastal ecosystems.Across these ancient lineages,colony-founding larvae anchor themselves either by byssus production or by cemented attachment.The latter mode of sessile life is strongly molded by left-right shell asymmetry during larval development of Ostreoida oysters such as Crassostrea hongkongensis.Here,we sequenced the genome of C.hongkongensis in high resolution and compared it to reference bivalve genomes to unveil genomic determinants driving cemented attachment and shell asymmetry.Importantly,loss of the homeobox gene Antennapedia(Antp)and broad expansion of lineagespecific extracellular gene families are implicated in a shift from byssal to cemented attachment in bivalves.Comparative transcriptomic analysis shows a conspicuous divergence between leftright asymmetrical C.hongkongensis and symmetrical Pinctada fucata in their expression profiles.Especially,a couple of orthologous transcription factor genes and lineage-specific shell-related gene families including that encoding tyrosinases are elevated,and may cooperatively govern asymmetrical shell formation in Ostreoida oysters. | Yang Zhang Fan Mao Shu Xiao Haiyan Yu Zhiming Xiang Fei Xu Jun Li Lili Wang Yuanyan Xiong Mengqiu Chen Yongbo Bao Yuewen Deng Quan Huo Lvping Zhang Wenguang Liu Xuming Li Haitao Ma Yuehuan Zhang Xiyu Mu Min Liu Hongkun Zheng Nai-Kei Wong Ziniu Yu | 2022 | Genomics, Proteomics & Bioinformatics2022，20，6： | 0 |
| 19 | Ranging Error Correction Based on a Prior Error Model显示文摘Wireless technology provides accurate positioning in indoor environments using time of arrival(TOA) based ranging techniques. However, the positioning accuracy is degraded due to the ranging errors caused by multipath and non-line-of-sight(NLOS) propagation. In this paper, a ranging error correction method is proposed to improve positioning performance. A TOA ranging error model(TREM) is built to provide the prior information for ranging error correction first. The mean value of TREM within a certain interval is used as the ranging error correction value(RECV). As the RECV may be unreasonable sometimes, we adjust it according to the actual positioning situation and then exploit the final RECV to correct ranging data. The experimental results show that the proposed method could well reduce ranging errors and the positioning performance is obviously improved when using corrected ranging data. | Xiaofei Wang Hongkun He Yan Xu Yang Lei | 2018 | China Communications2018，15，3： | 0 |
| 20 | Effects of main active components of rosemary on growth performance,meat quality and lipid metabolism in finishing pigs显示文摘Rosemary extracts have been widely used as feed additives in recent years.This study aimed to investigate the effects of rosmarinic acid(RA)and ursolic acid(UA),the main active components of rosemary,on growth performance,meat quality and lipid metabolism in finishing pigs.A total of 72 finishing pigs(Landrace;initial age of 150 d)were randomly divided into 3 treatments with 8 replicates of 3 pigs each,and fed a basal diet or diet containing 500 mg/kg of RA or UA.The results showed that dietary supplementation of RA or UA had no significant effect on the growth performance and carcass traits of finishing pigs(P>0.05).However,both RA and UA significantly increased the triglyceride(TG)level in soleus muscle(P<0.001).Supplementation of RA increased the expression of genes related to lipogenesis and transport including fatty acid synthase(FAS)(P<0.001),sterol regulatory element binding protein-1c(SREBP1c)(P<0.001)and peroxisome proliferator-activated receptorγ(PPARγ)(P<0.05),while UA increased the expression of fatty acid transport protein 1(FATP1),a gene related to lipid uptake(P<0.05).However,RA reduced the expression of adipogenesis-related gene acetyl-coenzyme A carboxylase a(ACCa)(P<0.01).Characterization of cecal microbiota indicated that RA increased the microbial richness(chao 1,P<0.001)and diversity(observed species,P<0.01).Further analysis of the genera revealed that RA increased the relative abundance of Bacteroides and g-UCG-005(P<0.05),and UA enriched Prevotella(P<0.001).Correlation analysis showed that g-UCG-005 was positively correlated with the expression of FAS,carnitine palmitoyl transferase 1B(CPT1B),SREBP1c and PPARγ(P<0.01).In conclusion,dietary supplementation of RA or UA may increase fat deposition in muscle of finishing pigs by regulating lipid metabolism and gut microbiota. | Qianjin Zhang Jiatai Gong Hongkun Xiang Ruizhi Hu Xizi Yang Jing Lv Wentao Zhang Ming Liu Xiong Deng Xupeng Yuan Ziyu He Yixuan Jiang Bie Tan Jianhua He Shusong Wu | 2023 | Animal Nutrition2023，，4： | 0 |
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