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| 1 | Hepatitis B Virus Gene in Liver Tissue Promotes Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients显示文摘 | Shin-Ichi Fujioka Hiroyuki Shimomura Yoshiaki Iwasaki Kozo Fujio Hiroshi Nakagawa Yasuhiro Onishi Shinjiro Takagi Hideaki Taniguchi Fumi Umeoka Hirofumi Nakajima Akio Moriya Katsuyuki Nanba Cheng-Yu Piao Toshiyuki Shinji Norio Koide Yasush Shiratori | 2003 | Digestive Diseases and Sciences2003，，10： | 1 |
| 2 | Lactic acid-mediated suppression of Helicobacter pylori by the oral administration of Lactobacillus salivarius as a probiotic in a gnotobiotic murine model显示文摘 | Yuji Aiba Nobuyuki Suzuki Abu M.A Kabir Atushi Takagi Yasuhiro Koga | 1998 | The American Journal of Gastroenterology1998，，11： | 1 |
| 3 | Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion显示文摘 | Chiao-Po Hsu Peiyong Zhai Takanobu Yamamoto Yasuhiro Maejima Shouji Matsushima Nirmala Hariharan Dan Shao Hiromitsu Takagi Shinichi Oka Junichi Sadoshima | 2010 | Circulation2010，，21： | 1 |
| 4 | Combined Administration of L-Cystine and L-Theanine Enhances Immol/Lune Functions and Protects against Influenza Virus Infection in Aged Mice显示文摘 | YASUHIRO TAKAGI SHIGEKAZU KURIHARA NATSUMI HIGASHI | 2010 | Journal of Veterinary Medical Science2010，72，2： | 1 |
| 5 | Activation of the Activin A-ALK-Smad pathway in systemic sclerosis显示文摘 | Kae Takagi Yasushi Kawaguchi Manabu Kawamoto Yuko Ota Akiko Tochimoto Takahisa Gono Yasuhiro Katsumata Masatoshi Takagi Masako Hara Hisashi Yamanaka | 2010 | Journal of Autoimmunity2010，，3： | 1 |
| 6 | Comparison of minimally invasive glaucoma surgery with trabecular micro-bypass stent and microhook ab interno trabeculotomy performed in conjunction with cataract surgery显示文摘AIM: To evaluate the effectuality and safety of cataract surgery combined with either ab interno trabeculotomy by the microhook(μLOT) or a single i Stent? trabecular bypass implantation(i Stent) in eyes with cataract and mild-tomoderate glaucoma. METHODS: This study enrolled subjects with mild-tomoderate open angle glaucoma with visually significant cataract who used two or more ophthalmic antiglaucoma agents between 60 and 90 y of age. Patients underwent cataract surgery cooperated with either implantation of an i Stent(i Stent-phaco) or excisional goniotomy with the μLOT(μLOT-phaco). Patients underwent μLOT-phaco in the eye with lower the mean deviation, according to the Humphrey field analyzer, while i Stent-phaco was carried out on the other eye. Intraocular pressure(IOP) pre-and post-surgery, alterations in anterior chamber flare(ACF), and corneal endothelial cell density(ECD) were estimated.RESULTS: Twenty subjects were enrolled(mean age: 73.6±7.3 y). The mean medicated preoperative IOP was 16.7 mm Hg in the μLOT and 16.2 mm Hg in the i Stent eyes. The mean final IOP at 12 mo was 13.6 mm Hg in the μLOT eyes and 13.6 mm Hg in the i Stent eyes, representing a 17.8% and 17.2% reduction, respectively. The preoperative ACF in the μLOT eyes was 9.5 pc/ms and it returned to normal in 30 d postoperatively, with a value of 11.4 pc/ms. In the i Stent eyes, ACF was 9.6 pc/ms preoperatively and it returned to normal by 7 d postoperatively(11.2 pc/ms atday 7), demonstrating that postoperative inflammation was less in the i Stent eyes. The corneal ECD in both groups was not significantly decreased.CONCLUSION: In this study, i Stent and μLOT are both effective through 12 mo of follow-up. Safety is more favorable in the i Stent eyes, based on early anterior chamber inflammation. | Naoto Tokuda Yasushi Kitaoka Ayaka Tsukamoto Yasuhiro Toyoda Yusuke Yamada Kana Sase Hitoshi Takagi | 2022 | International Journal of Ophthalmology(English edition)2022，15，7： | 1 |
| 7 | Effect of Three Types of Mixed Anesthetic 'Agents Ahernate toKetamine in Mice 显示文摘 | Sumiko KAWAI Yasuhiro TAKAGI Shiro KANEKO | 2011 | Tokyo experimental animals2011，60，5： | 1 |
| 8 | Humanized Antibody to Human Interleukin-6 Receptor Inhibits the Development of Collagen Arthritis in Cynomolgus Monkeys显示文摘 | Masahiko Mihara Masao Kotoh Norihiro Nishimoto Yasuhiro Oda Eiji Kumagai Nobuhiro Takagi Kunihiko Tsunemi Yoshiyuki Ohsugi Tadamitsu Kishimoto Kazuyuki Yoshizaki Yasuhisa Takeda | 2001 | Clinical Immunology2001，，： | 1 |
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