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| 1 | Clinical features and predictors of remission in children under the age of 7 years with Graves’disease显示文摘Importance:Graves’disease(GD)is rare in children under the age of 7 years.Children with this disease exhibit greater thyrotoxicity at diagnosis and require a longer course of medical therapy,compared with pubertal and postpubertal children and adults.Objective:To investigate the clinical features and identify predictors of remission in children under the age of 7 years with GD.Methods:This retrospective study included 77 children who were diagnosed with GD under the age of 7 years and were treated in the Department of Endocrinology,Beijing Children’s Hospital from 2010 to 2018.Clinical manifestations,laboratory data,and follow-up records were collected for all patients.Children who achieved remission of treatment with methimazole were compared with those who had persistent disease to identify which variables were associated with remission;multiple logistic regression and Cox regression analyses were used to evaluate interactions among predictive variables.Results:Sixty-three boys and 14 girls were included;the median age at diagnosis was 4.2 years(interquartile range:3.2-5.3 years).Forty-six(56.7%)patients had no family history of thyroid disease,17 patients had family history of thyroid disease and 14 patients with unknown family history.Of the 77 patients,18(23.4%)patients achieved remission of treatment with methimazole and 59 patients did not;moreover,51(66.2%)had Graves’ophthalmopathy.Univariate analyses revealed no significant differences between the remission group and non-remission group in terms of age at diagnosis,sex,initial goiter size,or initial thyroid hormone concentration.However,there were a trend of correlation between the initial level of thyroid peroxidase antibody(TPOAb)and remission status(univariate analysis OR 1.002,P=0.038;multivariate analysis OR 1.004,P=0.019).Similar results were observed in univariate analysis of the initial thyrotropin receptor antibody(TRAb)level,but this association was not significant in multivariate analysis.Cox regression analyses revealed that children with high TRAb level required longer duration of remission,compared with low TRAb level(OR 0.950,95%CI 0.904-0.997,P=0.037).Interpretation:Initial TRAb level was an independent predictor of remission outcome in young children under the age of 7 years with GD.Initial TRAb level may predict the likelihood of remission in patients with young-age-of-onset GD. | Yi Gu Xuejun Liang Ming Liu Di Wu Wenjing Li Bingyan Cao Yuchuan Li Chang Su Jiajia Chen Chunxiu Gong | 2020 | Pediatric Investigation2020，4，3： | 3 |
| 2 | Study on the quality evaluation metrics for compressed spaceborne hyperspectral data显示文摘Based on the raw data of spaceborne dispersive and interferometry imaging spectrometer,a set of quality evaluation metrics for compressed hyperspectral data is initially established in this paper.These quality evaluation metrics,which consist of four aspects including compression statistical distortion,sensor performance evaluation,data application performance and image quality,are suited to the comprehensive and systematical analysis of the impact of lossy compression in spaceborne hyperspectral remote sensing data quality.Furthermore,the evaluation results would be helpful to the selection and optimization of satellite data compression scheme. | LI Xiaohui ZHANG Jing LI Chuanrong LIU Yi LI Ziyang ZHU Jiajia ZENG Xiangzhao | 2015 | Instrumentation2015，2，1： | 3 |
| 3 | Scleral TGF-β1 and Smad3 expression is altered by TCM Bu Jing Yi Shi Tablets in guinea pigs with form-deprivation myopia显示文摘Objective:To explore whether the traditional Chinese medicine(TCM)Bu Jing Yi Shi Tablets alters the expression of scleral TGF-b1 and Smad3 in guinea pigs with formdeprivation myopia(FDM).Methods:Sixty-five guinea pigs were randomly divided into control,model,low-,medium-,and high-dose treatment groups.Except for the control group,FDM was induced by covering the right eye of each animal with opaque latex.The treatment groups were gavaged with different suspension concentrations of Bu Jing Yi Shi Tablets.Refraction and axial length were performed before and after myopia induction.At the end of the experiment,all right eyes were extracted,and scleral sections were prepared for staining and TGF-b1 and Smad3 immunohistochemistry.Scleral thickness and area,the scleral fibroblast quantity,and scleral TGFb1 and Smad3 expressions were measured.Results:The 5 FDM groups had the same initial axial length and diopter,the final diopter and axial length of the model group were significantly increased compared with the control group and treatment groups(P<.01).The axial length of each treatment group decreased as the dose decreased compared with the model group(P<.01);the total scleral area(P<.05 e.01)and the number of scleral fibroblasts(P<.01)in the model group were significantly lower than the treatment groups.Both the TGF-b1 and Smad3 integral optical densities in the model group were significantly lower than the control and medium-and high-dose treatment groups(P<.01).TGF-b1 and Smad3 mRNAs in the model group were decreased compared with the control group,but increased in expression after treatment. | Ya Mo Yi Wang Bin Cao Jiajia Zhang Guoting Ren Ting Yang | 2016 | Journal of Traditional Chinese Medical Sciences2016，3，2： | 3 |
| 4 | Green Fabrication of Multifunctional Three‑Dimensional Superabsorbent Nonwovens with Thermo‑Bonding Fibers显示文摘Disposable hygiene products have evolved into the important parts for millions of people around the world,enhancing the convenience of daily lives.However,development of the disposable hygiene products is restricted by unsustainable production technology,complicated operation process,and poor liquid absorption performance of the absorbent core.Herein,integrated and three-dimensional(3D)multifunctional superabsorbent nonwovens with liquid-triggered fragrance release was prepared via green,fast and scalable multi efect hot-air anchoring method which physically crosslinking the joint thermobonding fbers and anchoring fragrance microcapsules/super absorbent polymer(SAP)onto adjacent thermo-bonding fbers simultaneously.The resulting composite nonwovens could three-dimensionally absorb water 33.14 times of its own weight without gel blockage between SAP,and correspondingly release increased intensity fragrance along with enhancing amount of water absorption.Absorption rate t1 and t2 is 83.62%and 50.62%higher than the commercial specimen respectively,and the air permeability is increased by 226.88%compared with the commercial specimen.The superabsorbent nonwovens with controllable fragrance release and odorant synergistic has the potential to be practically applied to functional textiles felds because of the excellent liquid absorption and controlled fragrance release performance,and is easy to be produced on a sustainable,pollution-free and large-scale industrial production. | Jiajia Ma Nan Zhang Ying Cheng Xingran Kou Yunwei Niu Xiangyu Jin Qinfei Ke Yi Zhao | 2022 | Advanced Fiber Materials2022，4，2： | 3 |
| 5 | Hormonal changes throughout puberty in boys:an observational study on the treatment outcome of congenital hypogonadotropic hypogonadism显示文摘To the Editor:It is difficult to capture the exact time of initiation of puberty in normal children,such as when breasts in girls and testicles in boys begin to grow,especially in boys.As a result,research on the detailed patterns of physical development during puberty and the cut-off values and changes of hormones at the initiation of puberty and developmental maturation is rare.It is generally believed that hormonal changes during puberty are a direct result of the stimulating effect of luteinizing hormone(LH)on initiation of puberty;[1]thus,LH is widely accepted as an indicator to evaluate initiation of puberty.However,researchers have not yet reached an agreement on the cut-off value of LH,especially in boys. | Xiaoya Ren Yuanyuan Tian Guoshuang Feng Yi Wang Beibei Zhang Bingyan Cao Jiajia Chen Chunxiu Gong | 2022 | Chinese Medical Journal2022，，3： | 2 |
| 6 | A fluorescent probe operating under weak acidic conditions for the visualization of HOCl in solid tumors in vivo显示文摘Levels of reactive oxygen species(ROS)in cancer cells or in the tumor microenvironment differ noticeably from those in normal cells and cellular microenvironments because ROS play important roles in all aspects of tumor physiology.However,due to the lack of adequate tools,it is difficult to study the relationship between ROS,especially certain types of ROS(e.g.,HOCl),and cancer.We report herein an HOCl-specific fluorescent probe,FDOCl-20,containing a thiocarbamide group as a receptor,for the visualization of HOCl in solid tumors in vivo.This probe displays high selectivity and sensitivity to HOCl,and is appropriate for use in acidic conditions,including the tumor microenvironment.Using FDOCl-20 as a tool,we can visualize HOCl in solid tumors in vivo.Importantly,the fluorescent intensity of FDOCl-20 is proportional to tumor volume.Thus,FDOCl-20 is a useful tool to investigate the relationship between HOCl and the physiological processes of tumors. | Peng Wei Lingyan Liu Wei Yuan Jiajia Yang Ruohan Li Tao Yi | 2020 | Science China Chemistry2020，63，8： | 2 |
| 7 | Green approach to fabrication of a super-hydrophobic film on copper and the consequent corrosion resistance显示文摘 | Peng Wang Dun Zhang Ri Qiu Yi Wan Jiajia Wu | 2013 | Corrosion Science2013，，： | 2 |
| 8 | Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy显示文摘Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal scle rosis.There is no effective treatment for cognitive impairment.Medial septum cholinergic neurons have been reported to be a potential target for controlling epileptic seizures in tempo ral lobe epile psy.However,their role in the cognitive impairment of temporal lobe epilepsy remains unclear.In this study,we found that patients with temporal lobe epile psy with hippocampal sclerosis had a low memory quotient and severe impairment in verbal memory,but had no impairment in nonverbal memory.The cognitive impairment was slightly correlated with reduced medial septum volume and medial septum-hippocampus tra cts measured by diffusion tensor imaging.In a mouse model of chronic temporal lobe epilepsy induced by kainic acid,the number of medial septum choline rgic neurons was reduced and acetylcholine release was reduced in the hippocampus.Furthermore,selective apoptosis of medial septum cholinergic neurons mimicked the cognitive deficits in epileptic mice,and activation of medial septum cholinergic neurons enhanced hippocampal acetylcholine release and restored cognitive function in both kainic acid-and kindling-induced epile psy models.These res ults suggest that activation of medial septum cholinergic neurons reduces cognitive deficits in temporal lobe epilepsy by increasing acetylcholine release via projections to the hippocampus. | Junzi Chen Yu Wang Cong Chen Qingyang Zhang Shuang Wang Yi Wang Jiajia Fang Ying Wang | 2023 | Neural Regeneration Research2023，18，11： | 1 |
| 9 | Manganese oxide–graphene composite as an efficient catalyst for 4-electron reduction of oxygen in alkaline media显示文摘 | Jiajia Wu Dun Zhang Yi Wang Yi Wan | 2012 | Electrochimica Acta2012，，： | 1 |
| 10 | High-Efficiency Wastewater Purification System Based on Coupled Photoelectric–Catalytic Action Provided by Triboelectric Nanogenerator显示文摘It is of great importance to explore a creative route to improve the degradation e ciency of organic pollutants in wastewater.Herein,we construct a unique hybrid system by combining self-powered triboelectric nanogenerator(TENG)with carbon dots-TiO_(2)sheets doped three-dimensional graphene oxide photocatalyst(3 DGA@CDs-TNs),which can significantly enhance the degradation e ciency of brilliant green(BG)and direct blue 5 B(DB)owing to the powerful interaction of TENG and 3 DGA@CDs-TNs photocatalyst.The power output of TENG can be applied for wastewater purification directly,which exhibits a selfpowered electrocatalytic technology.Furthermore,the results also verify that TENG can replace conventional electric catalyst to remove pollutants e ectively from wastewater without any consumption.Subsequently,the unstable fragments and the plausible removal pathways of the two pollutants are proposed.Our work sheds light on the development of e cient and sustainable TENG/photocatalyst system,opening up new opportunities and possibilities for comprehensive utilization of random energy. | Shen Shen Jiajia Fu Jia Yi Liyun Ma Feifan Sheng Chengyu Li Tingting Wang Chuan Ning Hongbo Wang Kai Dong Zhong Lin Wang | 2021 | Nano-Micro Letters2021，13，12： | 1 |
| 11 | The Impacts of Highly Resourced Vocational Schools on Student Outcomes in China显示文摘Policymakers in developing countries have prioritized the mass expansion of vocational education and training(VET).This study examines whether the quality of VET in developing countries increases by investing greater resources per student.To achieve this goal,we examine the impacts of attending model schools(which have far more resources per student)on a range of student cognitive,non-cognitive,and behavioral outcomes.Using representative data from a survey of approximately 12,000 VET students from China,multivariate regression and propensity score matching analyses show that attending model vocational high schools do not benefit student outcomes,despite their substantially greater resources. | Guirong Li Jiajia Xu Liying Li Zhaolei Shi Hongmei Yi James Chu Elena Kardanova Yanyan Li Prashant Loyalka Scott Rozelle | 2020 | China & World Economy2020，28，6： | 1 |
| 12 | MAGI1 inhibits migration and invasion via blocking MAPK/ERK signaling pathway in gastric cancer显示文摘Objective: To explore the association of membrane-associated guanylate kinase inverted 1(MAGI1) with gastric cancer(GC) and the related molecular mechanisms.Methods: The reverse transcription-polymerase chain reaction(RT-PCR) and immunohistochemistry(IHC)were utilized to measure the MAGI1 expression level in GC tissues. Quantitative real-time PCR and Western blotting were used to ensure the MAGI1 expression in GC cell lines. Small hairpin RNA(sh RNA) was applied for knockdown of endogenous MAGI1 in GC cells. MTT assay and colony formation assay, scratch wounding migration assay and transwell chamber migration assay, as well as transwell chamber invasion assay were employed respectively to investigate the GC cell proliferation, migration and invasion in MAGI1-knockdown and control GC cells. The potential molecular mechanism mediated by MAGI1 was studied using Western blotting and RT- PCR.Results: RT-PCR and IHC verified MAGI1 was frequently expressed in matched adjacent noncancerous mucosa compared with GC tissues and the expression of MAGI1 was related to clinical pathological parameters. Functional assays indicated that MAGI1 knockdown significantly promoted GC cell migration and invasion. Further mechanism investigation demonstrated that one pathway of MAGI1 inhibiting migration and invasion was mainly by altering the expression of matrix metalloproteinases(MMPs) and epithelial-mesenchymal transition(EMT)-related molecules via inhibiting MAPK/ERK signaling pathway.Conclusions: MAGI1 was associated with GC clinical pathological parameters and acted as a tumor suppressor via inhibiting of MAPK/ERK signaling pathway in GC. | Shuqin Jia Jiajia Lu Tingting Qu Yi Feng Xiaohong Wang Caixia Liu Jiafu Ji | 2017 | Chinese Journal of Cancer Research2017，29，1： | 1 |
| 13 | Parallelized microfluidic droplet generators with improved ladder-tree distributors for production of monodisperseγ-Al_(2)O_(3)microspheres显示文摘In this paper,we present a parallelized microfluidic device with improved ladder-tree distributors for the scaled-up production of monodisperse microspheres.Owing to the improved distribution form comprising a ladder distributor in the center and tree distributors around the circumference,the uniformity of the generated droplets for our device was improved by 32.9%and 86.1%compared to those achieved in devices with conventional tree and ladder distributors,respectively,in the final production stage with 32 droplet generators,indicating the potential of our device for further scale-up while maintaining the monodispersity of the generated droplets.The effect of the 2D scale-up of our device was investigated by varying the continuous-phase flow rate and viscosity.Using our device,γ-Al_(2)O_(3)microspheres with a diameter of 598.1μm and a CV of 2.58%,as catalyst support for microreactors,were continuously synthesized at high production rate.The nickel-based catalyst prepared fromγ-Al_(2)O_(3)microspheres with large specific surface area and pore volume had an average NiO size of 14 nm,which was 60.9%of that supported on industrial support.The CO methanation conversion of the Ni@Al_(2)O_(3)microspheres was 1.7 times larger than Ni@Al_(2)O_(3)industrial support at 140℃. | Huilin Yi Shuliang Lu Jiajia Wu Yujun Wang Guangsheng Luo | 2022 | Particuology2022，20，3： | 1 |
| 14 | Global trends and regional differences in non-transport unintentional injuries mortality among children and adolescents, 1990 to 2019: results from the Global Burden of Disease 2019 study显示文摘Background::Non-transport unintentional injuries(NTUIs)are major public concerns,especially among children and adolescents in low-and middle-income countries.With environmental and cognitive changes,a recent systematic description of global trends and regional differences concerning NTUIs is urgently needed for the global agenda of relevant policy-making and intervention target findings.Methods::We used mortality,population,and socio-demographic-index(SDI)data from Global Burden of Disease 2019 to analyze the trends of NTUIs mortality.We applied the slope index of inequality(SII)and relative index of inequality(RII)to measure the absolute and relative inequality between countries and territories.The concentration curve and concentration index(CI)were also used to measure the inequality.We conducted a sensitivity analysis to make our findings credible.Results::In 2019,there were 205,000 deaths due to NTUIs among children and adolescents aged 5 to 24 years,which decreased from 375,000 in 1990.In 2019,the age-standardized mortality rate(ASMR)was 8.13 per 100,000,ranging from the lowest in the Netherlands(0.90 per 100,000)to the highest in the Solomon Islands(29.34 per 100,000).The low-middle SDI group had the highest ASMR of NTUIs,while the low SDI group had the slowest decrease.After excluding the death caused by'exposure to forces of nature'and'other unintentional injuries',drowning accounted for the most deaths in almost every SDI group,gender,and age group,but the major causes of death varied in different subgroups.For example,animal contact was a major cause in low and low-middle SDI groups but less in high SDI groups,while high and high-middle SDI groups had a higher proportion of deaths for foreign body and poisonings.The SII showed a declining trend,but the RII and CI did not,which might indicate that inequality was persistent.Similar results were found in the sensitivity analysis.Conclusions::Despite the declining trend of the mortality rate and the narrowing gap between countries,there were still a large number of children and adolescents dying from NTUIs,and those experiencing social-economic disadvantages remained at high mortality.Embedding the prevention of NTUIs into sustainable development goals might contribute to the progress of reducing death and inequalities,which ensures that no one is left behind. | Yunfei Liu Yanhui Dong Xiaojin Yan Ning Ma Jiajia Dang Jingshu Zhang Panliang Zhong Luo Li Zhiyong Zou Yi Song Jun Ma | 2022 | Chinese Medical Journal2022，135，17： | 1 |
| 15 | Differential diagnosis between epileptic seizures and psychogenic nonepileptic seizures based on semiology显示文摘Psychogenic nonepileptic seizures present as paroxysmal symptoms and signs mimicking epileptic seizures.The gold standard test is the synchronous recording by video,electrocardiogram and electroencephalogram.However,video electroencephalogram is not available at many centers and not entirely independent of semiology.Recent studies have focused on semiological characteristics distinguishing these two circumstances.Clinical signs and symptoms provide important clues when making differential diagnosis.The purpose of this review is to help physicians differentiating psychogenic nonepileptic seizures better from epileptic seizures based on semiology,and improve care for those patients. | Xiaohui Xiang Jiajia Fang Yi Guo | 2019 | Acta Epileptologica2019，1，1： | 0 |
| 16 | Combined Effect of Outdoor Time and Other Modifiable Factors on Myopia Incidence Among Children and Adolescents—9 PLADs,China,2020显示文摘Summary What is already known about this topic?Myopia has been identified as a significant emerging challenge and policy priority among children and adolescents in China by the Ministry of Education and seven other departments.Limited research has been conducted to investigate the collective impact of outdoor time and other modifiable factors on the incidence of myopia. | Panliang Zhong Yunfei Liu Ning Ma Jiajia Dang Di Shi Shan Cai Ziyue Chen Yanhui Dong Peijin Hu Jun Ma Patrick W.C Lau Randall S.Stafford Yi Song | 2024 | China CDC weekly2024，6，9： | 0 |
| 17 | Excitatory somatostatin interneurons in the dentate gyrus drive a widespread seizure network in cortical dysplasia显示文摘Seizures due to cortical dysplasia are notorious for their poor prognosis even with medications and surgery,likely due to the widespread seizure network.Previous studies have primarily focused on the disruption of dysplastic lesions,rather than remote regions such as the hippocampus.Here,we first quantified the epileptogenicity of the hippocampus in patients with late-stage cortical dysplasia.We further investigated the cellular substrates leading to the epileptic hippocampus,using multiscale tools including calcium imaging,optogenetics,immunohistochemistry and electrophysiology.For the first time,we revealed the role of hippocampal somatostatin-positive interneurons in cortical dysplasia-related seizures.Somatostatin-positive were recruited during cortical dysplasia-related seizures.Interestingly,optogenetic studies suggested that somatostatin-positive interneurons paradoxically facilitated seizure generalization.By contrast,parvalbumin-positive interneurons retained an inhibitory role as in controls.Electrophysiological recordings and immunohistochemical studies revealed glutamate-mediated excitatory transmission from somatostatin-positive interneurons in the dentate gyrus.Taken together,our study reveals a novel role of excitatory somatostatin-positive neurons in the seizure network and brings new insights into the cellular basis of cortical dysplasia. | Yang Zheng Cenglin Xu Jinyi Sun Wenjie Ming Sijie Dai Yuying Shao Xiaoyun Qiu Menghan Li Chunhong Shen Jinghong Xu Fan Fei Jiajia Fang Xuhong Jiang Guoqing Zheng Weiwei Hu Yi Wang Shuang Wang Meiping Ding Zhong Chen | 2023 | Signal Transduction and Targeted Therapy2023，8，6： | 0 |
| 18 | Efficacy and mechanism of methyl salicylate in the enhancement of skin delivery of herbal medicines显示文摘Objective: To elucidate the molecular mechanism(s) by which methyl salicylate enhances the skin delivery of herbal ingredients with diverse lipophilicity.Methods: The toxicity of methyl salicylate on skin cell lines was evaluated using the MTT assay. The Franz diffusion cell method was used to measure the permeability enhancing activities of methyl salicylate for five herbal ingredients with a range of lipophilicities. The interaction between methyl salicylate and the stratum corneum(SC) was observed by using an infrared spectroscopy technique. Moreover, the solubilities and SC-vehicle partition coefficient were determined to monitor the impact of methyl salicylate on the drug thermodynamic activities and partition into the SC layer, respectively.Results: Compared with azone(1-dodecylazacycloheptan-2-one), methyl salicylate showed lower toxicity to skin cells in terms of the IC50 values. The in vitro skin permeation studies showed that methyl salicylate could greatly improve the cumulative amounts or steady state flux of the selected model drugs with the exception of osthole, which indicated that methyl salicylate was prone to promote the skin delivery of hydrophilic drugs. The Fourier transform infrared spectroscopy studies revealed that methyl salicylate mainly interacted with SC lipids, leading to the disruption of the orderly arrangement of the SC.In addition, methyl salicylate had no obvious effect on the drug thermodynamic activity and partition into the SC.Conclusion: Methyl salicylate could effectively promote the skin delivery of relatively hydrophilic ingredients in externally used traditional Chinese medicines(TCM) without obvious cytotoxicity. | Jingyan Wang Xinyu Zhao Jiajia Chen Xin Li Doudou Hao Tingting Li Kai Mei Yi Lan Qing Wu | 2021 | Journal of Traditional Chinese Medical Sciences2021，8，4： | 0 |
| 19 | Adaptable 'bubble particles' prepared by green aqueous phase reshaping for completely removing odor显示文摘Facile and ecofriendly loading of micro/nano function-specific substances to create functional materials is a trend being pursued by researchers.However,current micro/nano particles loading approaches are often hindered by issues such as uneven distribution,unsatisfactory stability and complicate procedure.In this work,we present an aqueous phase reshaping method that only utilizes the moisture to fabricate the'bubble particles',which could perfectly cater to the topography of the substrate.The green preparation of bubble particles adopts an absolutely zero-pollution method,realizing the firm loading of particles on the substrate.Integrating the preparation and loading of particles overcomes the traditional complicate process,while the aqueous phase reshaping ensures uniform and firm loading of the'bubble particles'onto the substrate.Our mechanism demonstrates a significant enhancement in the interface relation after aqueous phase reshaping,with a 121-fold increase in contact surface area achieved by reducing the height by 1μm.Furthermore,we explore for the first time the influence of the nature of the receiving substrate on the interface morphology of particles during electrostatic spraying,which has important guiding significance for the interface relationship of electrostatic spraying and even electrostatic spinning materials.We also screen out the natural antibacterial essential oil linalool as the effective specialized antibacterial agent,which can specifically inhibit the odor-producing Proteus in urine,with an antibacterial rate of up to 100%.Taken together,this simple,ecofriendly method for fabricating functional materials with optimal interface stability appears highly promising for use in various products formed by electrostatic spraying/spinning. | Jiajia Ma Yichang Xia Tienan Zhao Wenfeng Hu Weifeng Zhang Qinfei Ke Yi Zhao | 2024 | Nano Research2024，17，3： | 0 |
| 20 | Preparation of Carboxymethylcellulose from Waste Paper显示文摘We aimed at producing sodium carboxymethylcellulose (CMC) from waste paper cellulose.For this etherification,the raw material was waste paper,the cellulose was initially alkalized with NaOH,the etherifying agent was sodium chloroacetate,and the reaction medium was water or ethanol.The method provided by us,i e,a method for preparing CMC from waste paper,was environment-friendly,could be easily implemented,and could be conveniently applied to make waste paper efficiently used with high profit,and to expand the range of usable raw materials for CMC production.We successfully synthesized CMC and prepared CMC plastic membrane.This practice changes waste into valuables,which is beneficial to our living environment.For preparation of CMC,one of the crucial factors is appropriate pretreatment of the cellulose from waste paper.The pretreatment was done with a self-built hydrolysis method.We experimentally examined the effects of the mass ratios of reactants,reaction temperature,time,and reaction environment of homogeneous or heterogeneous on CMC yield.The innovative points of this research could be stated as follows:the reaction activity of cellulose was improved by pre-hydrolysis;synthesizing CMC with cellulose from waste paper changes waste into valuables is beneficial to our living environment;and a freezing treatment for the cellulose-alkali mixture was innovatively added.The effects were exhibited by a desired final conversion efficiency. | 何杰 WANG Dali LONG Lirong HUANG Yali CUI Chunxiang YI Jiajia YANG Shengyang WANG Yuchang | 2021 | Journal of Wuhan University of Technology(Materials Science)2021，36，4： | 0 |
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