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| 1 | The spatial-temporal pattern and influencing factors of negative air ions in urban forests, Shanghai, China显示文摘Negative air ions are natural components of the air we breathe. Forests are the main continuous natural source of negative air ions(NAI). The spatio-temporal patterns of negative air ions were explored in Shanghai, based on monthly monitoring in 15 parks from March 2009 to February 2010. In each park, sampling sites were selected in forests and open spaces. The annual variation in negative air ion concentrations(NAIC) showed peak values from June to October and minimum values from December to January. NAIC were highest in summer and autumn, intermediate in spring, and lowest in winter. During spring and summer, NAIC in open spaces were significantly higher in rural areas than those in suburban areas. However, there were no significant differences in NAIC at forest sites among seasons. For open spaces, total suspended particles(TSP) were the dominant determining factor of NAIC in summer, and air temperature and air humidity were the dominant determining factors of NAIC in spring, which were tightly correlated with Shanghai's ongoing urbanization and its impacts on the environment. It is suggested that urbanization could induce variation in NAIC along the urban-rural gradient, but that may not change the temporal variation pattern. Furthermore, the effects of urbanization on NAIC were limited in non-vegetated or less-vegetated sites, such as open spaces, but not in well-vegetated areas, such as urban forests. Therefore, we suggest that urban greening, especially urban forest, has significant resistance to theeffect of urbanization on NAIC. | Hong Liang Xiaoshuang Chen Junguang Yin Liangjun Da | 2014 | Journal of Forestry Research2014，25，4： | 19 |
| 2 | A Review on Graphene-Based Gas/Vapor Sensors with Unique Properties and Potential Applications显示文摘Graphene-based gas/vapor sensors have attracted much attention in recent years due to their variety of structures, unique sensing performances, room-temperature working conditions, and tremendous application prospects, etc.Herein, we summarize recent advantages in graphene preparation, sensor construction, and sensing properties of various graphene-based gas/vapor sensors, such as NH_3, NO_2, H_2, CO, SO_2, H_2S, as well as vapor of volatile organic compounds.The detection mechanisms pertaining to various gases are also discussed. In conclusion part, some existing problems which may hinder the sensor applications are presented. Several possible methods to solve these problems are proposed, for example, conceived solutions, hybrid nanostructures, multiple sensor arrays, and new recognition algorithm. | Tao Wang Da Huang Zhi Yang Shusheng Xu Guili He Xiaolin Li Nantao Hu Guilin Yin Dannong He Liying Zhang | 2016 | Nano-Micro Letters2016，8，2： | 18 |
| 3 | Salt-responsive genes in rice revealed by cDNA microarray analysis显示文摘We used cDNA microarrays containing ~9,000 unigenes to identify 486 salt responsive expressed sequence tags (ESTs) (representing ~450 unigenes) in shoots of the highly salt-tolerant rice variety, Nona Bokra (Oryza sativa L. Ssp.Indica pv. Nona). Some of the genes identified in this study had previously been associated with salt stress. Howeverthe majority were novel, indicating that there is a great number of genes that are induced by salt exposure. Analysis of the salt stress expression profile data of Nona provided clues regarding some putative cellular and molecular processes that are undertaken by this tolerant rice variety in response to salt stress. Namely, we found that multiple transcription factors were induced during the initial salt response of shoots. Many genes whose encoded proteins are implicated in detoxification, protectant and transport were rapidly induced. Genes supporting photosynthesis were repressed and those supporting carbohydrate metabolism were altered. Commonality among the genes induced by salt exposure with those induced during senescence and biotic stress responses suggests that there are shared signaling pathways among these processes. We further compared the transcriptome changes of the salt-sensitive cultivar, IR28, with that of Nona rice. Many genes that are salt responsive in Nona were found to be differentially regulated in IR28. This study identified a large number of candidate functional genes that appear to be involved in salt tolerance and further examination of these genes may enable the molecular basis of salt tolerance to be elucidated. | Dai Yin CHAO Yong Hai LUO Min SHI Da LUO Hong Xuan LIN | 2005 | Cell Research2005，15，10： | 17 |
| 4 | Expression of intercellular adhesive molecule-1 in liver cancer tissues and liver cancer metastasis显示文摘Expressionofintercelularadhesivemolecule1inlivercancertissuesandlivercancermetastasisSUNJingJing,ZHOUXinDa,ZHOUGeandLIUYin... | SUN Jing Jing, ZHOU Xin Da, ZHOU Ge and LIU Yin Kun | 1998 | World Journal of Gastroenterology1998，4，3： | 12 |
| 5 | Phase tissue intercellular adhesion molecule-1 expression in nude mice human liver cancer metastasis model显示文摘Phasetissueintercelularadhesionmolecule1expressioninnudemicehumanlivercancermetastasismodelSUNJingJing,ZHOUXinDa,LIUYinK... | SUN JingJing, ZHOU XinDa, LIU YinKun and ZHOU GeKeywords liver neoplasms carcinoma, hepatocellular neoplasm metastasis intercellular adhesion molecule1 disease models, animal | 1998 | World Journal of Gastroenterology1998，4，4： | 10 |
| 6 | Two New Flavonoid Glycosides from Chrysanthemum morifolium显示文摘Two new flavonoid glycosides were isolated from the flowering heads of Chrysanthemum morifolium. Their structures were determined to be luteolin 4’-methoxy-7- O-(6'-O-acetyl)-β-D-glucopyranoside (1) and acacetin 7-O-(3'-O-acetyl)-β-D-glucopyranoside (2) by means of 1H and 13C NMR spectroscopic analysis, including 2D NMR technique. | Jian ZHANG An Wei DING You Bin LI Da Wei QIAN Jin Ao DUAN Zhi Qi YIN | 2006 | Chinese Chemical Letters2006，17，8： | 10 |
| 7 | Mechanically robust stretchable organic optoelectronic devices built using a simple and universal stencil-pattern transferring technology显示文摘Stretchable electronic and optoelectronic devices based on controllable ordered buckling structures exhibit superior mechanical stability by retaining their buckling profile without distortion in repeated stretch-release cycles.However,a simple and universal technology to introduce ordered buckling structures into stretchable devices remains a real challenge.Here,a simple and general stencil-pattern transferring technology was applied to stretchable organic lightemitting devices(SOLEDs)and polymer solar cells(SPSCs)to realize an ordered buckling profile.To the best of our knowledge,both the SOLEDs and SPSCs with periodic buckles exhibited the highest mechanical robustness by operating with small performance variations after 20,000 and 12,000 stretch-release cycles between 0%and 20%tensile strain,respectively.Notably,in this work,periodic-buckled structures were introduced into SPSCs for the first time,with the number of stretch-release cycles for the SPSCs improved by two orders of magnitude compared to that for previously reported random-buckled stretchable organic solar cells.The simple method used in this work provides a universal solution for low-cost and high-performance stretchable electronic and optoelectronic devices and promotes the commercial development of stretchable devices in wearable electronics. | Da Yin Nai-Rong Jiang Yue-Feng Liu Xu-Lin Zhang Ai-Wu Li Jing Feng Hong-Bo Sun | 2018 | Light(Science & Applications)2018，7，1： | 9 |
| 8 | Change rules of a stratospheric airship's envelope shape during ascent process显示文摘Stratospheric airship is a special near-space air vehicle,and has more advantages than other air vehicles,such as long endurance,strong survival ability,excellent resolution,low cost,and so on,which make it an ideal stratospheric platform.It is of great significance to choose a reasonable and effective way to launch a stratospheric airship to the space for both academic research and engineering applications.In this paper,the non-forming launch way is studied and the method of differential pressure gradient is used to study the change rules of the airship's envelope shape during the ascent process.Numerical simulation results show that the head of the envelope will maintain the inflatable shape and the envelope under the zero-pressure level will be compressed into a wide range of wrinkles during the ascent process.The airship's envelope will expand with the ascent of the airship and the position of the zero-pressure level will move downward constantly.At the same time,the envelope will gradually form a certain degree of stiffness under the action of the inner and external differential pressure.The experimental results agree well with the analytical results,which shows that the non-forming launch way is effective and reliable,and the analytical method has exactness and feasibility. | Zhao Shuai Liu Dongxu Zhao Da Wu Gang Yin Shi Zhou Pan | 2017 | Chinese Journal of Aeronautics2017，30，2： | 7 |
| 9 | Inflammation inhibitory effects of sirolimus and paclitaxel-eluting stents on interleukin-1β-induced coronary artery in-stent restenosis in pigs显示文摘背景冠的动脉 in-stent 狭窄(ISR ) 和迟了的 stent 血栓作为 stenting 的重要复杂并发症留下。对 sirolimus 和 paclitaxel-eluting stents 的发炎反应在 interleukin (IL ) 劝诱的一个猪狭窄模特儿被调查 -1.Methods 微型猪(n=12;2-3 月旧、称的 25-30 kg ) 受到 thoracotomy。中间的左前面的下降冠的动脉和左降声调符号的片断(10 公里) 冠的动脉被暴露并且无菌地包了,一个棉花网孔与 IL-1 (5 g ) 浸泡了。在 2 个星期以后,动物是 anesthetized,量的冠的动脉 X 线摄影法(QCA ) 被执行。狭窄地点为 stent 插入被使随机化进三个组:一个 sirolimus-eluting stent (SES ) 组(FirebirdTM, n=7 ) ,一个 paclitaxel-eluting stent (足) 组(TAXUSTM, n=9 ) ,并且一个赤裸金属的 stent (BMS ) 组(YINYITM, Dalian Yinyi Biomaterials 发展有限公司,中国, n=8 ) 。三不同 stents 随机被植入进狭窄片断。单核白血球 chemoattractant protein-1 (MCP-1 ) 的表示,肿瘤坏死 factor-alpha (TNF-) , P-selectin 和脉管的房间粘附 molecule-1 (VCAM-1 ) 被 .Results QCA 显示出的反向的联合抄写的聚合酶链反应(RT-PCR ) 决定在 IL-1 的严重狭窄对待片断。SES 和足组晚显示出更低的 1 月的 angiographic 在 stent 和损害以内的腔损失(LLL ) 与由后续 QCA 的 BMS (P 0.05 ) 相比。SES 在由后续 QCA 在猪减少 1 月的发炎损害比足的显示出更低的 LLL ((0. | ZHOU Xu-chen HUANG Rong-chong ZHANG Bo YIN Da LIANG Bin WANG Shao-peng GUAN Qi-gang SUN Xi-zhuo MIAO Zhi-lin HE Xue-zhi HAN Feng-tong CHENG Ying ZHANG Li ZENG Ding-yin | 2010 | Chinese Medical Journal2010，，17： | 6 |
| 10 | NECK LEAF 1, a GATA type transcription factor, modulates organogenesis by regulating the expression of multiple regulatory genes during reproductive development in rice显示文摘在 monocot 米饭种类 Oryza sativa L. ,最惹人注目的词法过程之一在繁殖开发期间是有上面的 internodes (合众国际社) 的顺序的延伸的圆锥花序开发的同时发生。阐明内在的分子的机制,我们克隆米饭基因颈叶 1 (NL1 ) ,什么时候变异,它在 flowering 时间,有簇叶丛生的苞的更小的圆锥花序和反常合众国际社延伸模式导致延期。NL1 基因与一个单个锌手指领域,和它的抄本编码一个 GATA 类型抄写因素在苞 primordia 主要被检测,它通常在野类型的植物堕落。在转基因的植物的 NL1 的 Overexpression 经常产生严重生长延迟,不太植物的 phytomers 和更小的叶子,建议 NL1 起在器官区别的一个重要作用。PLASTOCHRON1 (PLA1 ) 的新奇变异的等位基因,知道在调整叶开始起一个关键作用的基因,在这研究被识别。基因分析表明了在 nl1 和 pla1 之间的一个相互作用,与 PLA1 在上游的代理的 NL1。表示水平和 PLA1 的空间模式被发现在 nl1 被改变变异。而且, flowering, Hd3a 和 OsMADS1 的二个管理者的表示,也在 nl1 异种被影响。根据这些调查结果,我们建议 NL1 是通过在米饭在繁殖开发期间调整 PLA1 和另外的规章的基因的表示调制并且协调 organogenesis 的一个内在的因素。 | Liping Wang Hengfu Yin Qian Qian Jun Yang Chaofeng Huang Xiaohe Hu Da Luo | 2009 | Cell Research2009，19，5： | 6 |
| 11 | Cobalt-catalyzed Photochemical Methoxycarbonylation of Olefins with Carbon Dioxide under Ambient Conditions显示文摘The methoxycarbonylations of cyclohexene and 1-decene with CO2 can take place under ambient conditions by catalysis of [Co]([Co]=Co(acac)2. Co(OAc)2. CoCl2 ) in the presence of ultraviolet irradiation. | Jing Mei YIN Ming GUO Rui WANG Guang Yun ZHOU Da Bin GAO Xiang Sheng WANG Xin Wen GUO Jian Qin ZHUANG | 2000 | Chinese Chemical Letters2000，11，3： | 5 |
| 12 | Mizoribine versus mycophenolate mofetil or intravenous cyclophosphamide for induction treatment of active lupus nephritis显示文摘 | Feng Xuebing Gu Fei Chen Weiwei Liu Yan Wei Hua Liu Lin Yin Songlou Da Zhanyun Sun Lingyun | 2014 | Chinese Medical Journal2014，，21： | 5 |
| 13 | Hypoxia/oxidative stress alters the pharmacokinetics of CPU86017-RS through mitochondrial dysfunction and NADPH oxidase activation显示文摘 | Jie GAO Xuan-sheng DING Yu-mao ZHANG De-zai DAI Mei LIU Can ZHANG Yin DA | 2013 | Acta Pharmacologica Sinica2013，34，12： | 4 |
| 14 | CDH13 Genetic Polymorphisms, Adiponectin and Ischemic Stroke: a Chinese Family-based Sib-pair Study显示文摘Objective To understand the relationships between CDH13(T-cadherin) genetic polymorphisms, adiponectin levels and ischemic stroke, and possible interactions between CDH13 polymorphisms and other risk factors. Methods We recruited 342 Chinese ischemic stroke sib pairs. We genotyped rs4783244 and rs7193788 on CDH13 using time-of-flight mass spectrometry genotyping technology and measured total and high-molecular weight(HMW) adiponectin levels. We investigated associations between SNPs and ischemic stroke, and interactions between SNPs and other risk factors using multi-level mixed-effects regression model. Results In individuals without ischemic stroke, CDH13 rs4783244 was associated with total adiponectin levels(per T: Coef =-0.257, P = 0.001). CDH13 rs7193788 was associated with total adiponectin levels(per A: Coef =-0.221, P = 0.001) and HMW adiponectin levels(per A: Coef =-0.163, P = 0.003). rs7193788 was significantly associated with ischemic stroke(GA/AA vs. GG: OR = 1.55, 95% CI: 1.07 to 2.24, P = 0.020) after Bonferroni correction(α = 0.025). There was an interaction between rs7193788 and diabetes(P = 0.036). Compared to diabetes-free individuals with rs7193788 GG genotype, diabetes patients with rs7193788 GA/AA genotypes had higher risks for ischemic stroke(OR = 2.64, 95% CI: 1.58-4.40, P < 0.001). Conclusion CDH13 genetic polymorphisms are associated with adiponectin levels and ischemic stroke. An interaction is found between CDH13 SNP and diabetes for ischemic stroke. | CHEN Li SUN Ke Xin JUAN Juan FANG Kai LIU Kuo WANG Xue Yin WANG Ling YANG Chao LIU Xiao Qiang LI Jing TANG Xun WU Yi Qun QIN Xue Ying WU Tao CHEN Da Fang HU Yong Hua | 2017 | Biomedical and Environmental Sciences2017，30，1： | 4 |
| 15 | Anti-cyclic citrullinated peptide antibody predicts the development of rheumatoid arthritis in patients with undifferentiated arthritis显示文摘Background:Clinical outcomes of undifferentiated arthritis(UA)are diverse,and only 40%of patients with UA develop rheumatoid arthritis(RA)after 3 years.Discovering predictive markers at disease onset for further intervention is critical.Therefore,our objective was to analyze the clinical outcomes of UA and ascertain the predictors for RA development.Methods:We performed a prospective,multi-center study from January 2013 to October 2016 among Chinese patients diagnosed with UA in 22 tertiary-care hospitals.Clinical and serological parameters were obtained at recruitment.Follow-up was undertaken in all patients every 12 weeks for 2 years.Predictive factors of disease progression were identified using multivariate Cox proportional hazards regression.Results:A total of 234 patients were recruited in this study,and 17(7.3%)patients failed to follow up during the study.Among the 217 patients who completed the study,83(38.2%)patients went into remission.UA patients who developed RA had a higher rheumatoid factor(RF)-positivity(42.9%vs.16.8%,χ^2=8.228,P=0.008),anti-cyclic citrullinated peptide(CCP)antibodypositivity(66.7%vs.10.7%,χ^2=43.897,P<0.001),and double-positivity rate of RF and anti-CCP antibody(38.1%vs.4.1%,χ^2=32.131,P<0.001)than those who did not.Anti-CCP antibody but not RF was an independent predictor for RA development(hazard ratio 18.017,95%confidence interval:5.803–55.938;P<0.001).Conclusion:As an independent predictor of RA,anti-CCP antibody should be tested at disease onset in all patients with UA. | Chun Li Yan Zhang Hui Song Jie Gao Dong-Bao Zhao Qi Zhu Dong-Yi He Li Wang Xiang-Pei Li Xu-Dong Liu Wei-Guo Xiao Xin-Yu Wu Hua-Xiang Wu Wei Tu Shao-Xian Hu Xin Wang Zhi-Jun Li Zhi-Min Lu Zhan-Yun Da Bo Liang Xiao-Min Liu Jin-Wei Zhao Ling Li Feng Han Wu-Fang Qi Wei Wei Xu Ma Zhen-Bin Li Gui-Min Zheng Feng-Xiao Zhang Yi Li You-Lian Wang Guang-Hui Ling Jin-Wei Chen Xiao-Qiang Hou Jing Zhang Qing-Ping Chen Chang-Lian Liu Yan Zhang Jia-Shun Zeng Qing-Hua Zou Yong-Fei Fang Yin Su Zhan-Guo Li | 2019 | Chinese Medical Journal2019，，24： | 4 |
| 16 | Photo-promoted carbonylation of chloroalkanes with carbon monoxide by non-precious metal catalysts显示文摘The photo-promoted carbonylation of chloroalkanes with carbon monoxide was carried out under ambient conditions with copper and cadmium salts catalysts. The results indicated that the corresponding esters were produced with three salt catalysts, i.e. CuBr2, CuCl2 and CdI2. Among these catalysts, CdI2 was the most efficient in terms of ester yield and selectivity, particularly, 60% yield and 75% selectivity in the carbonylation of chlorocyclohexane were achieved. Furthermore, the yield and selectivity of the ester can be improved greatly by adding tri-n-butylamine in the CuBr2 and CuCl2 catalyst systems. On the other hand, the carbonylation did not proceed with single CdCl2, however, the catalytic activity of CdCl2 was increased greatly with NaIá2H2O as additive. As a result, we suggest that iodide ion plays an important role in the catalyst system of the cadmium salts. | Hong Wei Wang Ying Ping Jia Da Bin Gao Jing Mei Yin Guang-Yun-Zhou Shen Min Li | 2007 | Chinese Chemical Letters2007，18，7： | 3 |
| 17 | Entry into Major Groups Retaining Taxol via Sinenxan A显示文摘Compound 1 as a key intermediate of 1, 7, 9-trideoxytaxol was synthesized in ten steps from a biosynthetically available taxane, Sinenxan A. The key steps in the synthesis were deoxygenation at C-14, allylic oxidation at C-13 and construction of the oxetane ring. | Meng ZHANG, Da Li YIN*, Ji Yu GUO, Xiao Tian LIANG Institute of Materia Medica, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100050 | 2002 | Chinese Chemical Letters2002，13，2： | 3 |
| 18 | A Risk Prediction Model for Ischemic Stroke in Southern Chinese Population:Impact of Multiple Genetic Variants and Clinical/Lifestyle Factors显示文摘With a global prevalence of 7.7 million,ischemic stroke(IS)is one of the leading causes of death and disability worldwide.In China,IS alone contributed to 69.6%of stroke events and accounted for 37.1%of the mortality/disability rate[1].IS is a complex disease that is known to be associated with various genetic variants and clinical and lifestyle risk factors[2].Genome-wide association studies(GWAS)provided evidence for the occurrence of more than 160 IS-associated single nucleotide polymorphisms(SNPs).In terms of clinical risk factors,patients with a history of chronic diseases like hypertension,dyslipidemia,and diabetes mellitus,display a higher risk of developing IS.Among the various lifestyle components,leading a sedentary lifestyle,smoking,and having an unhealthy diet are known to be associated with the risk of IS.Thus,integration of various genetic,clinical,and lifestyle variables might prove to be highly beneficial in the prediction and prevention of IS at the individual level[3]. | YE Cheng Yin LI Jin Mei WU Jing Hua LI Zheng XIAO Juan YIN Xiao Yu WANG Da Hui XU Guo Zhang YANG Lei | 2021 | Biomedical and Environmental Sciences2021，34，8： | 2 |
| 19 | A Highly Regioselective Deacetylation of Taxanes显示文摘A highly regioselective O-deacetylation of taxanes at C-5 position was accomplished by treatment with t-BuOK and a possible mechanism was proposed. | Meng ZHANG, Da Li YIN*, Ji Yu GUO, Xiao Tian LIANG Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050 | 2002 | Chinese Chemical Letters2002，13，6： | 2 |
| 20 | A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities显示文摘A new sesquiterpene polyol ester was isolated from the leaves of Celastrus angulatus. itsstructure was determined as 1 6. 2 6. 9 a-triacetoxy-8 a-(a-hydroxyl-isobutyryloxy)-15-benzoyloxy-4 a-hydroxy-dihydroagarofuran by means of NMR. MS and IR spectral analysis.Preliminary biological study on antitumor activity revealed that this compound showed strongnonselective cytotoxicity against four of the NCI panel cell lines. | Wei Ping YIN Tian Zeng ZHAO Ling Jie GAO Da Peng ZOU Jian Xun KANG(Institute of Chemistry,Henan Academy of Sciences Zhengzhou 450003 Centre of Instrumental Analysis. Zhengzhou University. Zhengzhou 450052) | 1999 | Chinese Chemical Letters1999，10，6： | 2 |
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