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| 1 | A Review on Metal-Organic Framework-Derived Porous Carbon-Based Novel Microwave Absorption Materials显示文摘The development of microwave absorption materials(MAMs) is a considerable important topic because our living space is crowed with electromagnetic wave which threatens human’s health.And MAMs are also used in radar stealth for protecting the weapons from being detected.Many nanomaterials were studied as MAMs,but not all of them have the satisfactory performance.Recently,metal-organic frameworks(MOFs) have attracted tremendous attention owing to their tunable chemical structures,diverse properties,large specific surface area and uniform pore distribution.MOF can transform to porous carbon(PC) which is decorated with metal species at appropriate pyrolysis temperature.However,the loss mechanism of pure MOF-derived PC is often relatively simple.In order to further improve the MA performance,the MOFs coupled with other loss materials are a widely studied method.In this review,we summarize the theories of MA,the progress of different MOF-derived PC-based MAMs,tunable chemical structures incorporated with dielectric loss or magnetic loss materials.The different MA performance and mechanisms are discussed in detail.Finally,the shortcomings,challenges and perspectives of MOF-derived PC-based MAMs are also presented.We hope this review could provide a new insight to design and fabricate MOF-derived PC-based MAMs with better fundamental understanding and practical application. | Zhiwei Zhang Zhihao Cai Ziyuan Wang Yaling Peng Lun Xia Suping Ma Zhanzhao Yin Yi Huang | 2021 | Nano-Micro Letters2021，13，4： | 17 |
| 2 | Chromosome analysis of esophageal squamous cell carcinoma cell line KYSE 410-4 by repetitive multicolor fluorescence in situ hybridization显示文摘Chromosome aberrations are distinctive features of human malignant tumors. Analysis of chromosomal changes can illuminate the molecular mechanisms underlying the development and progression of cancer. To establish the technique of multicolor fluorescence in situ hybridization (M-FISH) for identifying chromosome aberrations in esophageal carcinoma cell line KYSE 410-4, four pools of 6-color whole-chromosome painting probes have been designed and hybridized on the same metaphase spread by four rounds of repetitive FISH. Repetitive 6-color M-FISH was successfully established and the cytogenetic abnormalities in KYSE 410-4 cells were characterized. Chromosome gains occurred at 2q, 3, 8, 17p, and X. An isochromosome 3q was visualized in the cell line, which might be one intermedi- ate mechanism leading to 3p losses and/or 3q gains. Furthermore, 16 structural arrangements were detected, including four derivative chromosomes. The rearrangement of the centromeric regions accounted for approximately 44% of all rearrangements. The results added a more complete and accurate information of the genetic alterations to the classical cytogenetic description of KYSE 410-4 and provided a detailed cytogenetic background data for appropriate use of the cell line. The established 6-color M-FISH was useful for analyzing chro- mosomes in the whole genome of human tumors. | Yiling Yang Jiayou Chu Yupeng Wu Manli Luo Xin Xu Yaling Han Yan Cai Qimin Zhan Mingrong Wang | 2008 | Journal of Genetics and Genomics2008，35，1： | 6 |
| 3 | Laparoscopic liver resection and the learning curve: a 14-year, single-center experience显示文摘 | Xiujun Cai Zheyong Li Yale Zhang Hong Yu Xiao Liang Renan Jin Feng Luo | 2014 | Surgical Endoscopy2014，，4： | 2 |
| 4 | Antioxidant, free radical scavenging, anti-inflammatory and hepatoprotective potential of the extract from Parathelypteris nipponica (Franch. et Sav.) Ching显示文摘 | Wei Fu Jinglou Chen Yaling Cai Yongfang Lei Liming Chen Lei Pei Daonian Zhou Xiaofei Liang Jinlan Ruan | 2010 | Journal of Ethnopharmacology2010，，3： | 1 |
| 5 | Correlation of genomic and expression alterations of AS3 with esophageal squamous cell carcinoma显示文摘Androgen-induced proliferation shutoff gene AS3, also known as APRIN, is a growth inhibitory gene that is initially implicated in prostate cancer. This gene is required for androgen-dependent growth arrest and is a primary target for 1,25(OH)2D3 and androgens. Alle- lic loss at AS3 locus has been linked to a variety of cancers. However, the correlation of genomic and expression alterations of AS3 with esophageal squamous cell carcinoma (ESCC) is not well established. In this study, the genomic and expression alterations of AS3 in ESCC and their clinical significance are evaluated. Loss of heterozygosity (LOH) analysis using an AS3 intragenic microsatellite marker D13S171 revealed 72% allelic loss at AS3 locus in ESCC, which is significantly correlated with higher pathological grade (P=0.042). RT-PCR examination showed that AS3 mRNA obviously decreased in 44% tumors and its down-regulation was correlated with the sex of patients (P=0.03). Furthermore, the correlation between genomic and expression alterations of AS3 gene was analyzed in 18 ESCC specimens, which indicated that the consistency between allelic loss and decreased mRNA expression of AS3 was relatively poor. The results of this study indicate that the aberrant expression of AS3 may be involved in the tumorigenesis of esophagus and is responsible for the male predominance of ESCC. | Yu Zhang Xiaoping Huang Jun Qi Cai Yan Xin Xu Yaling Han Mingrong Wang | 2008 | Journal of Genetics and Genomics2008，35，5： | 1 |
| 6 | Predicting Lung Cancers Using Epidemiological Data:A Generative-Discriminative Framework显示文摘Predictive models for assessing the risk of developing lung cancers can help identify high-risk individuals with the aim of recommending further screening and early intervention.To facilitate pre-hospital self-assessments,some studies have exploited predictive models trained on non-clinical data(e.g.,smoking status and family history).The performance of these models is limited due to not considering clinical data(e.g.,blood test and medical imaging results).Deep learning has shown the potential in processing complex data that combine both clinical and non-clinical information.However,predicting lung cancers remains difficult due to the severe lack of positive samples among follow-ups.To tackle this problem,this paper presents a generative-discriminative framework for improving the ability of deep learning models to generalize.According to the proposed framework,two nonlinear generative models,one based on the generative adversarial network and another on the variational autoencoder,are used to synthesize auxiliary positive samples for the training set.Then,several discriminative models,including a deep neural network(DNN),are used to assess the lung cancer risk based on a comprehensive list of risk factors.The framework was evaluated on over 55000 subjects questioned between January 2014 and December 2017,with 699 subjects being clinically diagnosed with lung cancer between January 2014 and August 2019.According to the results,the best performing predictive model built using the proposed framework was based on DNN.It achieved an average sensitivity of 76.54%and an area under the curve of 69.24%in distinguishing between the cases of lung cancer and normal cases on test sets. | Jinpeng Li Yaling Tao Ting Cai | 2021 | IEEE/CAA Journal of Automatica Sinica2021，8，5： | 1 |
| 7 | Antioxidant and hepatoprotective activity of ethanol extract of Arachniodes exilis (Hance) Ching显示文摘 | ZHOU Daonian RUAN Jinlan CAI Yaling | 2010 | Journal of Ethnopharmacology2010，129，2： | 1 |
| 8 | Research on the Activity Characteristics of Small Earthquake Swarms in the Muli Area of Sichuan Province显示文摘In this article,we relocated the seismic source location of the earthquakes in the Muli area of Sichuan,inverted the focal mechanism of the larger earthquakes and analyzed the relationship between the water level of the Jinping reservoir and the frequency of the earthquake swarm. The results show that:( 1) The epicenters of the relocated small earthquake swarms are distributed in a seismic zone,and the earthquake focal depths were in the range of 0- 12 km.( 2) By analyzing the earthquake swarm spatial distribution,we found that the swarms were generated by one branch fault on the west of Xiaojinhe fault.( 3) The focal mechanism of the three earthquakes with magnitude greater than 4. 0 is significantly different,with the shallow source thrust events affected by vertical stress,and the strike-slip events are related to regional stress tectonic activity. | Cai Yichuan Dai Shigui Wei Yaling | 2016 | Earthquake Research in China2016，30，2： | 0 |
| 9 | COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors显示文摘Abnormal glucose and lipid metabolism in COVID-19 patients were recently reported with unclear mechanism.In this study,we retrospectively investigated a cohort of COVID-19 patients without pre-existing metabolic-related diseases,and found new-onset in suli n resista nee,hyperglycemia,and decreased HDL-C in these patie nts.Mecha nistically,SARS-CoV-2 infecti on in creased the expression of RE1-silencing transcription factor(REST),which modulated the expression of secreted metabolic factors including myeloperoxidase,apelin,and myostatin at the transcriptional level,resulting in the perturbation of glucose and lipid metabolism.Furthermore,several lipids,including(±)5-HETE,(±)12-HETE,propionic acid,and isobutyric acid were identified as the potential biomarkers of COVID-19-induced metabolic dysregulation,especially in insulin resistance.Taken together,our study revealed insulin resistance as the direct cause of hyperglycemia upon COVID-19,and further illustrated the underlying mechanisms,providing potential therapeutic targets for COVID-19-induced metabolic complications. | Xi He Chenshu Liu Jiangyun Peng Zilun Li Fang Li Jian Wang Ao Hu Meixiu Peng Kan Huang Dongxiao Fan Na Li Fuchun Zhang Weiping Cai Xinghua Tan Zhongwei Hu Xilong Deng Yueping Li Xiaoneng Mo Linghua Li Yaling Shi Li Yang Yuanyuan Zhu Yanrong Wu Huichao Liang Baolin Liao Wenxin Hong Ruiying He Jiaojiao Li Pengle Guo Youguang Zhuo Lingzhai Zhao Fengyu Hu Wenxue Li Wei Zhu Zefeng Zhang Zeling Guo Wei Zhang Xiqiang Hong Wei kang Cai Lei Gu Ziming Du Yang Zhang Jin Xu Tao Zuo Kai Deng Li Yan Xinwen Chen Sifan Chen Chunliang Lei | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
| 10 | ADANES中核燃料循环的中子学研究显示文摘In an attempt to allow nuclear power to reach high resource utilization,sufficient nuclear safety,nuclear proliferation resistance and lower financial risk,the concept of accelerator-driven advanced nuclear energy system(ADANES)is proposed[1;2].ADANES consists of a burner system and a fuel recycling system.The burner system is constructed based on the existing principles of accelerator-driven system(ADS)by combining nuclear waste transmutation,nuclear fuel breeding,and safety power production.Then,the spent nuclear fuels(SNFs)obtained from the water reactor can be reprocessed in the simple high temperature dry reprocessing[3;4](HT-dry reprocessing).In this reprocessing,a part of the nuclides containing neutron poison in the SNFs can be separated and disposed,while the remaining nuclides can be reused to produce new fuel.Using this method,only a fraction of the fission products(FPs)is removed without fine partitioning. | Yan Xuesong Zhang Xunchao Zhang Yaling Cai Hanjie Yang Lei | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 11 | VAMP726 from maize and Arabidopsis confers pollen resistance to heat and UV radiation by influencing lignin content of sporopollenin显示文摘Sporopollenin in the pollen cell wall protects male gametophytes from stresses.Phenylpropanoid derivatives,including guaiacyl(G)lignin units,are known to be structural components of sporopollenin,but the exact composition of sporopollenin remains to be fully resolved.We analyzed the phenylpropanoid derivatives in sporopollenin from maize and Arabidopsis by thioacidolysis coupled with nuclear magnetic resonance(NMR)and gas chromatography–mass spectrometry(GC–MS).The NMR and GC–MS results confirmed the presence of p-hydroxyphenyl(H),G,and syringyl(S)lignin units in sporopollenin from maize and Arabidopsis.Strikingly,H units account for the majority of lignin monomers in sporopollenin from these species.We next performed a genome-wide association study to explore the genetic basis of maize sporopollenin composition and identified a vesicle-associated membrane protein(ZmVAMP726)that is strongly associated with lignin monomer composition of maize sporopollenin.Genetic manipulation of VAMP726 affected not only lignin monomer composition in sporopollenin but also pollen resistance to heat and UV radiation in maize and Arabidopsis,indicating that VAMP726 is functionally conserved in monocot and dicot plants.Our work provides new insight into the lignin monomers that serve as structural components of sporopollenin and characterizes VAMP726,which affects sporopollenin composition and stress resistance in pollen. | Wenqi Yang Dongdong Yao Haiyang Duan Junli Zhang Yaling Cai Chen Lan Bing Zhao Yong Mei Yan Zheng Erbing Yang Xiaoduo Lu Xuehai Zhang Jihua Tang Ke Yu Xuebin Zhang | 2023 | Plant Communications2023，4，6： | 0 |
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