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| 1 | Developing a bacteriophage cocktail for biocontrol of potato bacterial wilt显示文摘Bacterial wilt is a devastating disease of potato and can cause an 80% production loss. To control wilt using bacteriophage therapy, we isolated and characterized twelve lytic bacteriophages from different water sources in Kenya and China. Based on the lytic curves of the phages with the pathogen Ralstonia solanacearum, one optimal bacteriophage cocktail, P1, containing six phage isolations was formulated and used for studying wilt prevention and treatment efficiency in potato plants growing in pots. The preliminary tests showed that the phage cocktail was very effective in preventing potato bacterial wilt by injection of the phages into the plants or decontamination of sterilized soil spiked with R. solanacearum. Eighty percent of potato plants could be protected from the bacterial wilt(caused by R. solanacearum reference strain GIM1.74 and field isolates), and the P1 cocktail could kill 98% of live bacteria spiked in the sterilized soil at one week after spraying.However, the treatment efficiencies of P1 depended on the timing of application of the phages, the susceptibility of the plants to the bacterial wilt, as well as the virulence of the bacteria infected,suggesting that it is important to apply the phage therapy as soon as possible once there are early signs of the bacterial wilt. These results provide the basis for the development of bacteriophagebased biocontrol of potato bacterial wilt as an alternative to the use of antibiotics. | Cuihua Wei Junli Liu Alice Nyarnbura Maina Francis B Mwaura Junping Yu Chenghui Yan Ruofang Zhang Hongping Wei | 2017 | Virologica Sinica2017，32，6： | 8 |
| 2 | Electrochemical corrosion behavior of composite coatings of sealed MAO film on magnesium alloy AZ91D显示文摘 | Hongping Duan Keqin Du Chuanwei Yan Fuhui Wang | 2005 | Electrochimica Acta2005，，14： | 3 |
| 3 | Growth process of plasma electrolytic oxidation films formed on magnesium alloy AZ91D in silicate solution显示文摘 | Hongping Duan Chuanwei Yan Fuhui Wang | 2007 | Electrochimica Acta2007，，15： | 2 |
| 4 | Efficient production of pronuclear embryos in breeding and nonbreeding season for generating transgenic sheep overexpressing TLR4显示文摘Background: Brucella is a zoonotic Gram-negative pathogen that causes abortion and infertility in ruminants and humans. TLR4 is the receptor for LPS which can recognize Brucella and initiate antigen-presenting cell activities that affect both innate and adaptive immunity. Consequently, transgenic sheep over-expressing TLR4 are an suitable model to investigate the effects of TLR4 on preventing Brucellosis. In this study, we generated transgenic sheep overexpressing TLR4 and aimed to evaluate the effects of different seasons(breeding and non-breeding season) on superovulation and the imported exogenous gene on growth.Results: In total of 43 donor ewes and 166 recipient ewes in breeding season, 37 donor ewes and 144 recipient ewes in non-breeding season were selected for super-ovulation and injected embryo transfer to generate transgenic sheep.Our results indicated the no. of embryos recovered of donors and the rate of pronuclear embryos did not show any significant difference between breeding and non-breeding seasons(P > 0.05). The positive rate of exogenous TLR4 tested were 21.21 % and 22.58 % in breeding and non-breeding season by Southern blot. The expression level of TLR4 in the transgenic sheep was 1.5 times higher than in the non-transgenic group(P < 0.05). The lambs overexpressing TLR4 had similar growth performance with non-transgenic lambs, and the blood physiological parameters of transgenic and non-transgenic were both in the normal range and did not show any difference.Conclusions: Here we establish an efficient platform for the production of transgenic sheep by the microinjection of pronuclear embryos during the whole year. The over-expression of TLR4 had no adverse effect on the growth of the sheep. | Yan Li Di Lian Shoulong Deng Xiaosheng Zhang Jinlong Zhang Wenting Li Hai Bai Zhixian Wang Hongping Wu Juncai Fu Hongbing Han Jianzhong Feng Guoshi Liu Ling Lian Zhengxing Lian | 2017 | Journal of Animal Science and Biotechnology2017，8，1： | 2 |
| 5 | Differential response of multiple zebrafish hepatic F-box protein genes to 17α-ethinylestradiol treatment显示文摘Estrogens are accumulating in environment and their effects on a variety of reproductive processes and tumorigenesis were reported by previous study, but the mechanism of estrogen promoting neoplasia was still not clear. F-box protein (FBP) is the component of E3 ubiquitin ligase which takes part in a variety of key biological processes. In this study, using mature male zebrafish, which are more sensitive to estrogen treatment, we examined influence of 17α-ethinylestradiol (EE2) exposure on the expression of a series of hepatic FBP genes, which take part in a variety of biological processes, including tumorigenesis. The influence of EE2 on the expression of hepatic mRNA concentrations of FBP genes were quantified based on the expression of the optimal internal control gene in male zebrafish after 7-day exposure to EE2, from a low-dose concentration (1 ng/L) to environmentally relevant concentrations (10, 100 ng/L). Our results showed that EE2 exposure reduced the expression of fbxl14a, fbxl14b, fbxo25 and β-TRCP2b, but enchanced the expression of skp2. While the alterations in fbxl2, fbxw7, fbxo9, β-TRCP2a, fbxl18 and fbxo45 mRNA levels were not observed after EE2 exposure. Thus, our results showed that the expression of hepatic FBP genes exhibited differentially in male zebrafish exposed EE2. The changes of the expression level of FBP genes induced by EE2 may be an important clue to elucidate the correlations of estrogen and hepatic tumors. | Hongping Zheng Shifeng Li Zhili Wu Yunbin Zhang Shengnan Hu Yuanchang Yan Yiping Li | 2011 | Journal of Environmental Sciences2011，23，4： | 2 |
| 6 | Growth process of plasma electrolytic oxidation films formed on magnesium alloy AZ91D in silicate solution显示文摘 | Duan Hongping Yan Chuanwei Wang Fuhui | 2007 | Electrochimica Acta2007，52，： | 1 |
| 7 | Electrochemical corrosion behavior of composite coatings of sealed MAO film on magnesium alloy AZ91D显示文摘 | Hongping Duan Keqin Du Chuanwei Yan | 2006 | Electrochimica Acta2006，51，14： | 1 |
| 8 | Carbohydrate Polymers 显示文摘 | DAI Jun WU Yan CHEN Shangwei ZHU Song YIN Hongping WANG Min TANG Jian | 2010 | S2:6292010，2，： | 1 |
| 9 | Growth process of plasma electrolytic oxidation films formed on magnesium alloy AZ91D in silicate solution显示文摘 | Hongping Duan Chuanwei Yan Fuhui Wang | 2007 | Electrochimica Acta2007，52，： | 1 |
| 10 | Effect of electrolyte additives on performance of plasma electrolytic oxidation films formed on magnesium alloy AZglD显示文摘 | Hongping Duan Chuanwei Yan Fuhui Wang | 2007 | Electrochimica Acta2007，52，11： | 1 |
| 11 | Growth process of plasma electrolytic oxidation films formed on magnesium alloy AZ91D in silicate solution 显示文摘 | Duan Hongping Yan Chuanwei Wang Fuhui | 2007 | Electrochemical Acta2007，52，： | 1 |
| 12 | A dynamic, architectural plant model simulating resource- dependent growth显示文摘 | Yan Hongping Kang Mengzheng de Reffye P | 2004 | Annals of Botany2004，93，5： | 1 |
| 13 | Electrochemical corrosion behavior of composite coatings of sealed MAO film on magnesium alloy AZ91D显示文摘 | Duan Hongping Du Keqin Yan Chuanwei | 2006 | Electrochimica Acta2006，51，： | 1 |
| 14 | Cooperative fusion particle filter tracker显示文摘Robust visual tracking has become an important topic in the field of computer vision.Integrating multiple cues has proved to be a promising approach to visual tracking in situations where no single cue is suitable.In this work,a new particle filter based visual tracking algorithm is proposed.By introducing a new cooperative fusion strategy,the proposed tracker has better fault tolerance ability than the traditional methods.Experiments are performed in various tracking scenes to evaluate the proposed algorithm,and the results show improved tracking accuracy. | WANG LingFeng YAN HongPing PAN ChunHong | 2014 | Science China(Information Sciences)2014，57，8： | 1 |
| 15 | 2013~2017年中国空气质量改善与早产疾病负担改变显示文摘Preterm birth(PTB)is a leading cause of perinatal mortality and morbidity worldwide[1].Since maternal and fetal health protection has been included in the United Nations Sustainable Development Goals,identification of modifiable risk factors for PTB is particularly crucial.The Global Burden of Disease(GBD)Study 2019 recognized fine particulate matter(PM2.5)pollution as a risk factor for decreased gestational age and low birth weight. | Yixuan Jiang Yuan He Shenpeng Wu Renjie Chen Ying Yang Jihong Xu Ya Zhang Qiaomei Wang Haiping Shen Yiping Zhang Donghai Yan Zuoqi Peng Xudong Dong Hongping Zhang Lifang Jiang Huichu Li Yixiang Zhu Cong Liu Weidong Wang Xia Meng Tao Pei Ci Song Aaron Cohen Xu Ma Jing Cai Haidong Kan | 2022 | Science Bulletin2022，67，9： | 1 |
| 16 | Effect of electrolyte additives on performance of plasma electrolytic oxidation films formed on magnesium alloy AZ91D显示文摘 | Hongping Duan Chuanwei Yan Fuhui Wang | 2006 | Electrochimica Acta2006，，11： | 1 |
| 17 | A dynamic, architectural plant model simulating resource-dependent growth显示文摘 | Yan Hongping Kang Mengzhen de Reffye P Dingkuhn M | 2004 | Annals of Botany2004，93，5： | 1 |
| 18 | Electrochemical corrosion behavior of composite coatings of sealed MAO film on magnesium alloy AZ91D显示文摘 | DUAN Hongping DU Keqin YAN Chuanwei | 2006 | Eletrochimica Acta2006，51，14： | 1 |
| 19 | Electrochemical eorrosion behavior of composite coatings of sealed MAO film on magnesium alloy AZ 91D 显示文摘 | Duan Hongping Du Keqin Yan Chuanwei | 2006 | Electrochemical Acta2006，61，14： | 1 |
| 20 | Optimal Gestational Weight Gain for Women with Gestational Diabetes Mellitus—China,2011–2021显示文摘Summary What is already known about this topic?Joint effects of gestational weight gain(GWG)and hyperglycemia on adverse pregnancy outcomes suggest that lower optimal GWG is optimal for women with gestational diabetes mellitus(GDM).However,there is still a lack of guidelines.What is added by this report?Optimal weekly GWG range after diagnosis of GDM for underweight,normal-weight,overweight,and obese women was 0.37–0.56 kg/week,0.26–0.48 kg/week,0.19–0.32 kg/week,and 0.12–0.23 kg/week,respectively.What are the implications for public health practice?The findings may be used to inform prenatal counseling regarding optimal gestational weight gain for women with gestational diabetes mellitus,and suggest the need for weight gain management. | Jinlang Lyu Yin Sun Yuelong Ji Nana Liu Suhan Zhang Hang Lin Yaxin Wang Xuanjin Yang Shuai Ma Na Han Yang Mi Dan Zheng Zhifen Yang Hongping Zhang Yan Jiang Liangkun Ma Haijun Wang | 2023 | China CDC weekly2023，5，9： | 0 |
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