|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | Bonding of chemically treated titanium implants to bone 显示文摘 | Yan WQ Nakamura T Kobavashi M | 1997 | J Biomed Mater Res1997，37，2： | 1 |
| 3 | IrrE, a global regulator of extreme radiation resistance inDeinococcus radiodurans, enhances salt tolerance in Escherichia coli and Brassica napus显示文摘 | Pan J Wang J Zhou Z Yan Y Zhang W Lu W Ping S Dai Q Yuan M Feng B Hou X Zhang Y Ma R Liu T Feng L Wang L Chen M Lin M | 2009 | PloS One2009，4，2： | 1 |
| 4 | Effects of Yb3+on the corrosion resistance and deposition rate of electroless Ni-P deposits显示文摘 | Yan M Ying H G Ma T Y | 2008 | Applied Surface Science2008，255，5： | 1 |
| 5 | Theoretical and experimental study of PI control, adaptive control and variable structure control for converted traditional milling machines 显示文摘 | Huang S J Yan M T | 1993 | Int J Mach Tools & Manuf1993，33，5： | 1 |
| 6 | Channel coordination in supply chains with agents having mean-variance objectives显示文摘 | Choi T M Li D Yan H M | 2008 | Omega2008，36，4： | 1 |
| 7 | Challenges, design and analysis of a large-scale P2P-VoD system显示文摘 | HUANG YAN FU T Z J CHIU D M | 2008 | ACM SIGCOMM Computer Communication Review2008，38，4： | 1 |
| 8 | Greatly impaired migration of implanted aquapor in-4-deficient astroglial cells in mouse brain toward a site of in jury显示文摘 | Auguste K I Jin S Uchida K Yan D Manley G T Papadopou los M C etal | 2007 | FASEB J2007，21，： | 1 |
| 9 | Genetic purity testing of two-line hybrid rice seeds by ultrathin-layer isoelectric focusing of proteins显示文摘 | Zhao T Yan M Lu Y P Yang F Huang J Wang X F | 2005 | Seed Science and Technology2005，33，： | 1 |
| 10 | A comparison of three radiation models for the calculation of nozzle arcs显示文摘 | Dixon C M Yan J D Fang M T C | 2004 | J Phys D:Appl Phys2004，37，23： | 1 |
| 11 | Optimiza- tion of microwave-assisted extraction of phenolics from po- tato and its downstream waste using orthogonal array de- sign 显示文摘 | WU T YAN J LIU R H Marcone M F | 2012 | Food Chemistry2012，133，4： | 1 |
| 12 | Stabilization of pulse-to-pulse energy and width by gain-controlled prelase in laser-diode-pumped Q switched laser显示文摘 | P Yan M Gong T Xie | 2003 | Opt Eng2003，42，1： | 1 |
| 13 | Numerical simulation of nitrided layer growth and nitrogen distribution in ε-Fe2-3N, γ'-Fe4N and a-Fe during pulse plasma nitriding of pure iron显示文摘 | YAN M F YAN J H BELL T | 2000 | Modeling and Simulation in Materials Science and Engineering2000，8，4： | 1 |
| 14 | Mean-variance analysis of a single supplier and retailer supply chain under a returns policy显示文摘 | Choi T M Li D Yan H | 2008 | European J of Operational Research2008，184，1： | 1 |
| 15 | Mean-variance analysis of a single supplier and retailer supply chain under a returns policy显示文摘 | Choi T M Li D Yan H | 2008 | European Journal of Operational Research2008，184，1： | 1 |
| 16 | Generalized projective synchronization of chaotic nonlinear gyros coupled with dead-zone input显示文摘 | Hung M Yan J Liao T | | Chaos Soliton Fract0，35，1： | 1 |
| 17 | Enhanced glass-forming ability of a Zr-based bulk metallic glass with yttrium doping显示文摘 | Yan M Shen J Zhang T | 2006 | Journal of Non-Crystalline Solids2006，352，： | 1 |
| 18 | 查看详情显示文摘 | Yan L W Duan X R Ding X T Dong J Q Yang Q W Liu Y Zou X L Liu D Q Xuan W M Chen L Y Rao J Song X M Huang Y Mao W C Wang Q M Li Q Cao Z Li B Cao J Y Lei G J Zhang J H Li X D Chen W Cheng J Cui C H Cui Z Y Deng Z C Dong Y B Feng B B Gao Q D Han X Y Hong W Y | | 0，，： | 1 |
| 19 | Isolation and chemotaxonomic significance of tuberostemospironine-type alkaloids from Stemona tuberose显示文摘 | Ren W J Po M H Yan T X | 2006 | Phytochemistry2006，67，1： | 1 |
| 20 | Using molecular markers to identify two major loci controlling carotenoid contents in maize grain显示文摘 | Chander S Guo Y Q Yang X H Zhang J Lu X Q Yan J B Song T M Rocheford T R Li J S | 2007 | Theor Appl Genet2007，116，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员