|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Development and utilization of a new chemically-induced soybean library with a high mutation density显示文摘Mutagenized populations have provided important materials for introducing variation and identifying gene function in plants. In this study, an ethyl methanesulfonate(EMS)-induced soybean(Glycine max) population,consisting of 21,600 independent M_2 lines, was developed.Over 1,000 M_(4(5))families, with diverse abnormal phenotypes for seed composition, seed shape, plant morphology and maturity that are stably expressed across different environments and generations were identified. Phenotypic analysis of the population led to the identification of a yellow pigmentation mutant, gyl, that displayed significantly decreased chlorophyll(Chl) content and abnormal chloroplast development. Sequence analysis showed that gyl is allelic to Minn Gold, where a different single nucleotide polymorphism variation in the Mg-chelatase subunit gene(ChlI1a) results in golden yellow leaves. A cleaved amplified polymorphic sequence marker was developed and may be applied to marker-assisted selection for the golden yellow phenotype in soybean breeding. We show that the newly developed soybean EMS mutant population has potential for functional genomics research and genetic improvement in soybean. | Zhongfeng Li Lingxue Jiang Yansong Ma Zhongyan Wei Huilong Hong Zhangxiong Liu Jinhui Lei Ying Liu Rongxia Guan Yong Guo Longguo Jin Lijuan Zhang Yinghui Li Yulong Ren Wei He Ming Liu Nang Myint Phyu Sin Htwe Lin Liu Bingfu Guo Jian Song Bing Tan Guifeng Liu Maiquan Li Xianli Zhang Bo Liu Xuehui Shi Sining Han Sunan Hua Fulai Zhou Lili Yu Yanfei Li Shuang Wang Jun Wang Ruzhen Chang Lijuan Qiu | 2017 | Journal of Integrative Plant Biology2017，59，1： | 6 |
| 2 | Efficacy of Carbamazepine Combined with Botulinum Toxin A in the Treatment of Blepharospasm and Hemifacial Spasm显示文摘Purpose:To observe the efficacy of the combined treatment of carbamazepine and botulinum toxin A for blepharospasm and hemifacial spasm. Methods:Fifty-eight patients with either blepharospasm or hemifacial spasm were randomly divided into treatment and control groups. In the treatment group, 30 patients were administered with local intramuscular injections of botulinum toxin A and oral carbamazepine 100 mg/time,3 times/day for 60 days. Twenty-eight subjects in the control group under-went local intramuscular injections of botulinum toxin A only. Results:After combined treatment, the complete remission rate was 90%, which was significantly higher than that of the of the control group (67.9% , P<0.05,χ2 =4.733). However, no statistical significance was noted regarding the duration of therapeutic effects between the treatment group (range 14~40 weeks; 19.2 weeks on average) and control group (range 12~36 weeks; 18 weeks on average). Conclusion:The combined therapy of carbamazepine and topical injections of botulinum toxin A had increased efficacy in the treatment of blepharospasm or hemifacial spasm, but had no significant effect in terms of the duration of the therapeutic effect. | Xianhua Li Shaochun Lin Yanfei Hu Liya Liu Jubo Liu Yichun Hong | 2012 | Eye Science2012，27，4： | 2 |
| 3 | Tunable Dynamic Black Phosphorus/Insulator/Si Heterojunction Direct-Current Generator Based on the Hot Electron Transport显示文摘Static heterojunction-based electronic devices have been widely applied because carrier dynamic processes between semiconductors can be designed through band gap engineering.Herein,we demonstrate a tunable direct-current generator based on the dynamic heterojunction,whose mechanism is based on breaking the symmetry of drift and diffusion currents and rebounding hot carrier transport in dynamic heterojunctions.Furthermore,the output voltage can be delicately adjusted and enhanced with the interface energy level engineering of inserting dielectric layers.Under the ultrahigh interface electric field,hot electrons will still transfer across the interface through the tunneling and hopping effect.In particular,the intrinsic anisotropy of black phosphorus arising from the lattice structure produces extraordinary electronic,transport,and mechanical properties exploited in our dynamic heterojunction generator.Herein,the voltage of 6.1 V,current density of 124.0 A/m^(2),power density of 201.0 W/m^(2),and energy-conversion efficiency of 31.4%have been achieved based on the dynamic black phosphorus/AlN/Si heterojunction,which can be used to directly and synchronously light up light-emitting diodes.This direct-current generator has the potential to convert ubiquitous mechanical energy into electric energy and is a promising candidate for novel portable and miniaturized power sources in the in situ energy acquisition field. | Yanghua Lu Sirui Feng Runjiang Shen Yujun Xu Zhenzhen Hao Yanfei Yan Haonan Zheng Xutao Yu Qiuyue Gao Panpan Zhang Shisheng Lin | 2019 | Research2019，，1： | 2 |
| 4 | Recent progress in small molecule fluorescent probes for nitroreductase显示文摘Nitroreductase(NTR) is a member of flavin-containing enzymes that exists widely in bacteria. Hypoxia,which is a characteristic of locally advanced solid tumors, resulting from an imbalance between oxygen consumption and supply, can result in NTR overexpression. Using either nicotinamide adenine dinucleotide(NADH) or nicotinamide adenine dinucleotide phosphate(NADPH) as a source of reducing equivalents, NTR can catalyze the reduction of nitroaromatic compounds to the corresponding amines.Based on this reduction mechanism, NTR can be applied not only in the bioremediation and degradation of organic nitrogen compounds, but also in the development of NTR-targeted fluorescent probes to detect the hypoxic status of cancer cells. This review aims to provide a summary of the progress in fluorescent probes for NTR in recent years and elucidate the main fluorescent mechanisms that have been applied to design probes. | Wenjing Qin Chenchen Xu Yanfei Zhao Changmin Yu Sheng Shen Lin Li Wei Huang | 2018 | Chinese Chemical Letters2018，29，10： | 2 |
| 5 | Interfacial Built-In Electric Field-Driven Direct Current Generator Based on Dynamic Silicon Homojunction显示文摘Searching for light and miniaturized functional device structures for sustainable energy gathering from the environment is the focus of energy society with the development of the internet of things.The proposal of a dynamic heterojunction-based direct current generator builds up new platforms for developing in situ energy.However,the requirement of different semiconductors in dynamic heterojunction is too complex to wide applications,generating energy loss for crystal structure mismatch.Herein,dynamic homojunction generators are explored,with the same semiconductor and majority carrier type.Systematic experiments reveal that the majority of carrier directional separation originates from the breaking symmetry between carrier distribution,leading to the rebounding effect of carriers by the interfacial electric field.Strikingly,NN Si homojunction with different Fermi levels can also output the electricity with higher current density than PP/PN homojunction,attributing to higher carrier mobility.The current density is as high as 214.0 A/m^(2),and internal impedance is as low as 3.6 kΩ,matching well with the impedance of electron components.Furthermore,the N-i-N structure is explored,whose output voltage can be further improved to 1.3V in the case of the N-Si/Al2O3/N-Si structure,attributing to the enhanced interfacial barrier.This approach provides a simple and feasible way of converting low-frequency disordered mechanical motion into electricity. | Yanghua Lu Qiuyue Gao Xutao Yu Haonan Zheng Runjiang Shen Zhenzhen Hao Yanfei Yan Panpan Zhang Yu Wen Guiting Yang Shisheng Lin | 2020 | Research2020，，1： | 2 |
| 6 | Highly stable lithium anode enabled by self-assembled monolayer of dihexadecanoalkyl phosphate显示文摘Li has been considered as the ultimate anode material for high energy density secondary Li batteries.However,its practical application has been limited due to its low Coulombic efficiency(CE)and the formation of lithium dendrites.Recently,we have developed a microspherical Li-carbon nanotube(Li-CNT)composite material passivated with octadecylphosphonic acid(OPA)self-assembled monolayer(SAM)exhibiting suppressed lithium dendrite formation and improved environmental/electrochemical stability.In this work,we demonstrated the significantly enhanced passivation effects of a SAM using dihexadecanoalkyl phosphate(DHP),a molecule that is comprised of double hydrophobic alkyl chains and forms a denser SAM on surfaces with large curvature.As a result,the DHP SAM delivers superior environmental and electrochemical stability to the OPA passivated Li-CNT material.In specific,the DHP passivated Li-CNT composite(DHP-Li-CNT)delivers a high CE of 99.25%under a 33.3%depth of discharge(DOD)at 1 C,when it is paired with a LiFePO4 cathode.The evolution of the SAM during cycling and the effects of DOD and current density on the CE of the DHP-Li-CNT anode have also been investigated.The improved SAM passivation constitutes an important step in achieving the goal of practically applicable Li anodes. | Lei Zheng Feng Guo Tuo Kang Jin Yang Ya Liu Wei Gu Yanfei Zhao Hongzhen Lin Yanbin Shen Wei Lu Liwei Chen | 2020 | Nano Research2020，13，5： | 1 |
| 7 | Impact of l -arginine on hydrogen sulfide/cystathionine-γ-lyase pathway in rats with high blood flow-induced pulmonary hypertension显示文摘 | Wang Yanfei Shi Lin Du Junbao Tang Chaoshu | 2006 | Biochemical and Biophysical Research Communications2006，，2： | 1 |
| 8 | Exploration on the Reform of PBL Mode of Course:Comprehensive Experiment of Basic Medicine for Nursing Undergraduates in Colleges and Universities of Traditional Chinese Medicine显示文摘The undergraduate education of nursing science produces higher practical operational talents to the society,and the importance of experimental teaching cannot be ignored in the training of nursing students.The basic experimental teaching method of undergraduate nursing has been explored and reformed by the College of Basic Medicine of Guangxi University of Chinese Medicine.After the reform,the experimental teaching adopts the teaching method of PBL mode,and the experimental course is composed of several specific and important medical problems.The specific tasks involved in each problem include relevant morphological knowledge,functional knowledge,diagnostic and laboratory knowledge,and clinical medical knowledge.It makes the teaching content of experimental course more comprehensive,and leads to the transition from basic medicine to clinical medicine.This has gradually and effectively improved the practical ability,scientific research thinking,clinical comprehensive ability and learning interest of undergraduate nursing students. | Yue PENG Tiejian ZHAO Jiang LIN Meng XIA Yanfei WEI Yanhui CEN | 2020 | Medicinal Plant2020，11，4： | 1 |
| 9 | Impact of 1-arginine on hydrogen sulfide/cystathionine γ-lyase pathway in rats with high blood flow induced pulmonary hypertension 显示文摘 | Yanfei W Lin S Junbao D | 2006 | Biochem Biophys Res Commun2006，345，2： | 1 |
| 10 | Hot-melt extrusion promotes dissolution,extends“spring-parachute”process and inhibits crystallization in supersaturating microparticle systems显示文摘Despite the potential advantages of amorphism-induced supersaturation,the merit of new amorphiza-tion formation methods on the properties of the amorphous drug including the stability of the amor-phous state,dissolution/solubility,supersaturation,and'spring-parachute'process is still poorly understood,particularly for certain amorphous supersaturating drug delivery systems(aSDDS).The present work aimed to explore the detailed merit of current attractive amorphization manufacturing methods(i.g.,hot-melt extrusion(HME)technique)on the property improvement of aSDDS in form of amorphous solid dispersion microparticles by employing a model Bcs II drug nitrendipine and a polyvinylpyrrolidone-based model polymer copovidone.Many asDDS systems were developed by various methods,and their physicochemical properties were characterized by SEM,PXRD and DSC.HME-triggered amorphization induced superior supersaturation by the observation of the highest dissolution and solubility.HME induced the optimal supersaturation duration by the observed greatest extension of'spring-parachute'process(e.g,maximum AUCspring-parachute).HME technique is comparable with other techniques for the stabilization of amorphous state during storage.All aSDDS systems by HME and other methods showed improved long-term stability of the amorphous state in comparison to the pure amorphous drug.Fourier transformation infrared spectroscopy,Noyes-Whitney equation,nucleation theory and Gibbs free energy of transfer(△G)were used to analyze the underlying mechanisms.Mo-lecular mechanism studies indicated that HME caused a stronger crystallization inhibition effect in the asDDS systems than other methods,but molecular interaction is not a dominant mechanism for property enhancement caused by HME.For the mechanism associated with the polymer itself(PVPVA64),it could inhibit the drug recrystallization,solubilize the drug spontaneously and cause the improved molecular interactions in all aSDDS systems.This study provided a deep insight into detailed advantage of HME-triggered supersaturation/amorphization and facilitated the applications of the technique both in the field of particuology and in pharmaceutical industry. | Yanfei Zhang Huifeng Zhang Huan Yu Yinghui Ma Chengyi Hao Xiaoying Lin Yong Zhang Zhengqiang Li Xianrong Qi Jia Zeng Nianqiu Shi | 2023 | Particuology2023，，7： | 0 |
| 11 | A Novel Method for the Quantitative Detection of Sericin Content in Silk Fiber Based on the Ratio of Aspartate to Alanine显示文摘The development of a method for the quantitative determination of the sericin content ratio(SCR)is urgently needed for silk refining and the purification of silk fibroin for biomedical applications.In this work,a series of sericin/fibroin mixed samples with known SCRs were prepared by mixing initial samples of extracted sericin and fibroin from Bombyx mori silk.Significant differences were found in the contents of characteristic hydrophilic amino acids abundant in sericin and hydrophobic amino acids abundant in fibroin,and several linear relation-ships of SCR associated with the content ratios of Ser/Ala,Asp/Ala,Lys/Ala,Asp/Gly and Ser/Gly were estab-lished by amino acid analysis.Subsequently,the linear equation expressing SCR(%)as a function of the Asp to Ala content ratio X(%)was established as SCR=2.5634X−12.5587(R 2=0.9972).The results indicated that the SCR of degummed silks calculated by the equation is more objective and effective than the results obtained by the traditional weight loss method.Our study provides a novel approach for the sensitive and quantitative detection of the sericin content within the detection limit in unknown silks,which can contribute to quality control in the silk production process. | Yanfei Feng Jiaming Lin Longxing Niu Peng Pan Xueping Liu Linling Huang Ying Guo Mingzhong Li | 2023 | Journal of Renewable Materials2023，11，1： | 0 |
| 12 | Green process to recover magnesium chloride from residue solution of potassium chloride production plant显示文摘The green process to recover magnesium chlor-ide from the residue solution of a potassium chloride pro-duction plant,which comes from the leach solution of a potash mine in Laos,is designed and optimized.The res-idue solution contains magnesium chloride above 25 wt-%,potassium chloride and sodium chloride together below 5 wt-%and a few other ions such as Br-,SO_(2)-4and Ca2+.The recovery process contains two steps:the previous impurity removal operation and the two-stage evapora-tion-cooling crystallization procedure to produce magnes-ium chloride.The crystallized impurity carnallite obtained from the first step is recycled to the potassium chloride plant to recover the potassium salt.The developed process is a zero discharge one and thus fulfills the requirements for green chemical industrial production.The produced magnesium chloride is up to industrial criteria. | Lin WANG Yunliang HE Yanfei WANG Ying BAO Jingkang WANG | 2008 | Frontiers of Chemical Science and Engineering2008，2，4： | 0 |
| 13 | A Pore-Forming Strategy Toward Porous Carbon-Based Substrates for High Performance Flexible Lithium Metal Full Batteries显示文摘Self-standing carbon-based substrates with satisfied structural stability and property adjustability have promising applications in flexible lithium(Li)metal batteries(FLMBs).Current strategies for modifying carbon materials are normally carried out on powder carbon,and very few of them are suitable for self-standing carbon substrates.Herein,a pore-forming strategy based on the redox chemistry of metallic oxide nanodots is developed to prepare two porous carbon substrates for anode and cathode.Starting with cotton cloth,the resulting hollow carbon fibers substrate with nanopores effectively prevents from Li dendrites formation and large volume change in lithium metal anode(LMA).Simulations indicate that the porous structure leads to homogeneous ion flux,Li-ion concentration,and electric field during Li deposition.Li symmetrical cell based on this substrate remains stable for 8300 h with an ultralow voltage hysteresis of 9 mV.Via a similar route,porous carbon cloth substrate is obtained for subsequently seeding V_(2)O_(5)nanowires to prepare the cathode.The assembled FLMBs pouch cell delivers a capacity of 8.2 mAh with a high capacity retention of~100%even under dramatic deformation.The demonstrated strategy has far-reaching potential in preparing free-standing porous carbon-based materials for flexible energy storage devices. | Yanfei Li Shuyang Ye Jian Lin Yihan Song Xinglong Wu Jingping Zhang Changlu Shao Zhongmin Su Haizhu Sun Dwight S.Seferos | 2023 | Energy & Environmental Materials2023，6，3： | 0 |
| 14 | Sensitivity of N400 Effect During Speech Comprehension Under the Uni-and Bi-Modality Conditions显示文摘N400 is an objective electrophysiological index in semantic processing for brain.This study focuses on the sensitivity of N400 effect during speech comprehension under the uni-and bi-modality conditions.Varying the Signal-to-Noise Ratio(SNR) of speech signal under the conditions of Audio-only(A),Visual-only(V,i.e.,lip-reading),and Audio-Visual(AV),the semantic priming paradigm is used to evoke N400 effect and measure the speech recognition rate.For the conditions A and high SNR AV,the N400 amplitudes in the central region are larger;for the conditions of V and low SNR AV,the N400 amplitudes in the left-frontal region are larger.The N400 amplitudes of frontal and central regions under the conditions of A,AV,and V are consistent with speech recognition rate of behavioral results.These results indicate that audio-cognition is better than visual-cognition at high SNR,and visual-cognition is better than audio-cognition at low SNR. | Yanfei Lin Zhiwen Liu Xiaorong Gao | 2022 | Tsinghua Science and Technology2022，27，1： | 0 |
| 15 | Influence of colloidal nanosilica on hydration kinetics and properties of CaO/CaSO_(4)-activated slag binder显示文摘To solve the energy consumption and CO_(2) emission during cement production,the new binders must be developed as an alternative to cement.CaO/CaSO_(4)-activated slag binder is an eco-friendly and safe cementitious material;however,its low strength during initial stages limits its applications.In this study,colloidal nanosilica(CNS)was employed as an additive to improve the strength of CaO/CaSO_(4)-activated slag binder,and the effects of CNS on the workability,hydration kinetics,hydration products(type,quantity,and polymerization degree),and binder microstructure were thoroughly investigated.A moderate CNS content,through its nucleation effect,significantly increased the hydration rate of the nucleation and crystal growth(NG),phase boundary interaction(I)and diffusion(D)processes,which generated large quantities of calcium aluminosilicate hydrate(C-A-S-H)gel in the initial hydration stage.Meanwhile,the addition of CNS improved the polymerization degree of C-A-S-H gel.This amorphous reactant well-filled the pore space between slag particles and yielded a compact microstructure,consequently enhancing the binder strength.Considering the reduction in fluidity and the increase in production cost,the CNS mass fraction was controlled as3%,and the binder reached the satisfactory strengths of 3.87,24.47,31.43,and 41.78 MPa at 1,3,7,and 28 d,respectively. | Qing Liu Qingming He Ruoyun Li Yanfei Feng Xianjun Lyu Junxiang Wang Lin Li | 2022 | International Journal of Mining Science and Technology2022，32，6： | 0 |
| 16 | Pupillometry Analysis of Rapid Serial Visual Presentation at Five Presentation Rates显示文摘In this study,the effect of presentation rates on pupil dilation is investigated for target recognition in the Rapid Serial Visual Presentation(RSVP)paradigm.In this experiment,the RSVP paradigm with five different presentation rates,including 50,80,100,150,and 200 ms,is designed.The pupillometry data of 15 subjects are collected and analyzed.The pupillometry results reveal that the peak and average amplitudes for pupil size and velocity at the 80-ms presentation rate are considerably higher than those at other presentation rates.The average amplitude of pupil acceleration at the 80-ms presentation rate is significantly higher than those at the other presentation rates.The latencies under 50-and 80-ms presentation rates are considerably lower than those of 100-,150-,and 200-ms presentation rates.Additionally,no considerable differences are observed in the peak,average amplitude,and latency of pupil size,pupil velocity,and acceleration under 100-,150-,and 200-ms presentation rates.These results reveal that with the increase in the presentation rate,pupil dilation first increases,then decreases,and later reaches saturation.The 80-ms presentation rate results in the largest point of pupil dilation.No correlation is observed between pupil dilation and recognition accuracy under the five presentation rates. | Xi Luo Yanfei Lin Rongxiao Guo Xirui Zhao Shangen Zhang Xiaorong Gao | 2024 | Tsinghua Science and Technology2024，29，2： | 0 |
| 17 | Effect of Se-enriched Lactobacillus on Antibody of NDV of Broilers显示文摘This study was conducted to investigate the effect of Se-enriched lactobacillus on antibody of Newcastle Disease Virus(NDV)of broilers.One thousand day-old AA broiler chickens were selected from a chicken farm of Jinghai County,and the chickens were divided randomly into two groups,which respectively had five repeat groups with 100 chickens each,one named basal diet group,and the other named Se-enriched lactobacillus group.Corn soybean meal diet was selected for basal diet group,while 2%se-enriched lactobacillus was added into corn soybean meal diet for the other group.The method of feeding was free diet,drinking,and routine immunization program was adopted.This test period was 42 d.Two chickens were selected randomly in each repeat for slaughtering and collecting serums on the 14th,28th and 42nd d.Assessments on the effect of Se-enriched lactobacillus in antibody titer of NDV of broilers were made by hemagglutination-inhibition test.The results indicated that antibody titer of NDV was increased significantly by Se-enriched lactobacillus. | Yaowei LIN Yanfei LIU Jiande YANG Shunyi QIN | 2020 | Agricultural Biotechnology2020，9，5： | 0 |
| 18 | Event-Related Potentials Analysis on Perception of Moving Object at Different Speeds显示文摘For this research,electroencephalography(EEG)was analyzed to investigate the perception ability of the brain for moving objects at different speeds.In this experiment,total six kinds of videos regarding license plates were created,moving at distinct speed of 0.26 m/s,0.36 m/s,0.46 m/s,0.56 m/s,0.66 m/s,and 0.76 m/s,respectively.In the semantic priming paradigm,the N400 effect was analyzed for each speed.The ERP results demonstrated that the N400 amplitude gradually reduced with increasing speed.At the three lower speeds,N400 was evoked evidently and mainly distributed in the centro-posterior region.At the three higher speeds,no significant N400 effect was found.The results concluded that the perception ability of the brain declined with the acceleration of the object’s moving speed and that the brain recognized the detailed information of the moving object when its speed was lower than 0.46 m/s. | Yanfei Lin Zhiqiang Lu Ziwei Zhao Xi Luo Rongxiao Guo Xiaorong Gao | 2023 | Tsinghua Science and Technology2023，28，2： | 0 |
| 19 | Polarized Water Driven Dynamic PN Junction-Based Direct-Current Generator显示文摘There is a rising prospective in harvesting energy from the environment,as in situ energy is required for the distributed sensors in the interconnected information society,among which the water flow energy is the most potential candidate as a clean and abundant mechanical source.However,for microscale and unordered movement of water,achieving a sustainable direct-current generating device with high output to drive the load element is still challenging,which requires for further exploration.Herein,we propose a dynamic PN water junction generator with moving water sandwiched between two semiconductors,which outputs a sustainable direct-current voltage of 0.3 V and a current of 0.64μA.The mechanism can be attributed to the dynamic polarization process of water as moving dielectric medium in the dynamic PN water junction,under the Fermi level difference of two semiconductors.We further demonstrate an encapsulated portable power-generating device with simple structure and continuous direct-current voltage output of 0.11 V,which exhibits its promising potential application in the field of wearable devices and the IoTs. | Yanghua Lu Yanfei Yan Xutao Yu Xu Zhou Sirui Feng Chi Xu Haonan Zheng Zunshan Yang Linjun Li Kaihui Liu Shisheng Lin | 2021 | Research2021，，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员