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| 1 | Mapping coalmine goaf using transient electromagnetic method and high density resistivity method in Ordos City, China显示文摘The research about subsurface characteristics by using transient electromagnetic method(TEM) and high density resistivity method(HDRM) were already conducted in Ordos. The objective of this research is to detect coalmine goaf areas based on rock resistivity. The data processing using wavelet transform, three point smoothing, RES2 DINV and Maxwell processing software to obtain 2D resistivity structure. The results showed that the layers with maximum resistivity values(30e33 U m on Line 1, 30e31 U m on Line 2, 32e40 U m on Line3) are founded at station 1e7, and 14e20 on Line 1,13e18 on Line 2, and 8e13 and 16e20 on Line 3 which is predicted as goaf layer, and the minimum resistivity values(20e26 U m of TEM, 45e75 U m of HDRM) at the other layers. This resistivity difference was caused by the geology and characteristics of the study area which is located close by the cleugh with rich coal, so the goaf area distinguishable with aquifer layer and coal seam. The results were also significant accidents and serious destruction of ecological environment. | Guiju Wu Guangliang Yang Hongbo Tan | 2016 | Geodesy and Geodynamics2016，7，5： | 14 |
| 2 | Characteristics of the lunar samples returned by the Chang'E-5 mission显示文摘Forty-five years after the Apollo and Luna missions returned lunar samples,China's Chang’E-5(CE-5)mission collected new samples from the mid-latitude region in the northeastern Oceanus Procellarum of the Moon.Our study shows that 95%of CE-5 lunar soil sizes are found to be within the range of 1.40-9.35μm,while 95%of the soils by mass are within the size range of 4.84-432.27μm.The bulk density,true density and specific surface area of CE-5 soils are 1.2387 g/cm^(3),3.1952 g/cm^(3) and 0.56 m^(2)/g,respectively.Fragments from the CE-5 regolith are classified into igneous clasts(mostly basalt),agglutinate and glass.A few breccias were also found.The minerals and compositions of CE-5 soils are consistent with mare basalts and can be classified as low-Ti/low-Al/low-K type with lower rare-earth-element contents than materials rich in potassium,rare earth element and phosphorus.CE-5 soils have high FeO and low Mg index,which could represent a new class of basalt. | Chunlai Li Hao Hu Meng-Fei Yang Zhao-Yu Pei Qin Zhou Xin Ren Bin Liu Dawei Liu Xingguo Zeng Guangliang Zhang Hongbo Zhang Jianjun Liu Qiong Wang Xiangjin Deng Caijin Xiao Yonggang Yao Dingshuai Xue Wei Zuo Yan Su Weibin Wen Ziyuan Ouyang | 2022 | National Science Review2022，9，2： | 12 |
| 3 | Studies on the evolution process of rockbursts in deep tunnels显示文摘This paper focuses on the evolution processes of different types of rockbursts occurring in deep tunnels. A series of laboratory tests and in-situ monitoring in deep tunnels excavated by tunnel boring machine (TBM) and drill-and-blast (D&B) method have been conducted to understand the mechanisms and processes of the evolution of different types of rockbursts, including strain rockburst, strain-structure slip rockburst, immediate rockburst and time-delayed rockburst. Three different risk assessment methods are proposed to evaluate the intensity and potential failure depth of rockbursts. These methods can be applied before excavation and the results can be updated according to the real-time information during excavation. Two micro-seismicity based real-time warning systems have been established for predicting various intensities of rockbursts, such as slight, moderate, intensive and extremely intensive rockbursts. Meanwhile, the probability and intensity of the rockburst are also given. The strategy for excavation and support design has been suggested for various intensities of rockbursts before excavation. The strategy for dynamic control of the rockburst evolution process is also proposed according to the monitoring results. The methodology has been successfully applied to rockburst risk reduction for deep tunnels at Jinping II hydropower project. The results have illustrated the applicability of the proposed methodology and techniques concerning rockbursts. | Xiating Feng Bingrui Chen Shaojun Li Chuanqing Zhang Yaxun Xiao Guangliang Feng Hui Zhou Shili Qiu Zhouneng Zhao Yang Yu Dongfang Chen Huajun Ming | 2012 | Journal of Rock Mechanics and Geotechnical Engineering2012，4，4： | 11 |
| 4 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021，31，12： | 5 |
| 5 | Prevalence, risk factors, and survival associated with pulmonary hypertension and heart failure among patients with underlying coronary artery disease: a national prospective, multicenter registry study in China显示文摘Background: Coronary artery disease (CAD) is the commonest cause of heart failure (HF), whereas pulmonary hypertension (PH) has not been established or reported in this patient population. Therefore, we assessed the prevalence, risk factors, and survival in CAD-associated HF (CAD-HF) complicated with PH.Methods: Symptomatic CAD-HF patients were continuously enrolled in this prospective, multicenter registry study. Echocardiography, coronary arteriography, left and right heart catheterization (RHC), and other baseline clinical data were recorded. Patients were followed up and their survival was recorded.Results: One hundred and eighty-two CAD-HF patients were enrolled, including 142 with HF with a preserved ejection fraction (heart failure with preserved ejection fraction [HFpEF];left ventricular ejection fraction [LVEF] ≥50%) and 40 with a reduced ejection fraction (heart failure with reduced ejection fraction [HFrEF];LVEF < 50%). PH was diagnosed with RHC in 77.5% of patients. Patients with PH showed worse hemodynamic parameters and higher mortality. HFrEF-PH patients had worse survival than HFpEF-PH patients. CAD-HF patients with an enlarged left ventricular end-diastolic diameter and reduced hemoglobin were at higher risk of PH. Nitrate treatment reduced the risk of PH. Elevated creatinine and mean pulmonary arterial pressure (mPAP), diastolic pressure gradient (DPG) ≥7 mmHg, and previous myocardial infarction (MI) entailed a higher risk of mortality in CAD-HF patients with PH.Conclusions: PH is common in CAD-HF and worsens the hemodynamics and survival in these patients. Left ventricle enlargement and anemia increase the risk of PH in CAD-HF. Patients may benefit from nitrate medications. Renal impairment, elevated mPAP, DPG ≥7 mmHg, and previous MI are strong predictors of mortality in CAD-HF-PH patients.Trial Registration: ClinicalTrials.gov, NCT02164526. | Li Huang Lingpin Pang Qing Gu Tao Yang Wen Li Ruilin Quan Weiqing Su Weifeng Wu Fangming Tang Xiulong Zhu Jieyan Shen Jingzhi Sun Guangliang Shan Changming Xiong Shian Huang Jianguo He | 2022 | Chinese Medical Journal2022，，15： | 4 |
| 6 | Estimating Moho basement and faults using gravity inversion in Yushu-earthquake area,China显示文摘A gravity survey was conducted one month after the 2010 Yushu earthquake in the epicenter area.The cross-fault survey line was 500 km long,from Langqian county to Qingshuihe county,in a transition zone between Bayan Har block and Qiangtang block,in an area of high elevation,large undulating terrain,and complex geological features.An interpretation of the data was carried out together with other kinds of data,such as seismic exploration and magnetic exploration.The result shows that gravity is sensitive to fault boundary;the geologic structure of the region is complex at middle and upper depths,and the density profile reveals an eastward-pushing fault movement. | Yang Guangliang | 2012 | Geodesy and Geodynamics2012，3，2： | 4 |
| 7 | Gravity distribution characteristics and their relationship with the distribution of earthquakes and tectonic units in the Northe South seismic belt, China显示文摘The Northe South Seismic Belt(NSSB) is a Chinese tectonic boundary with a very complex structure, showing a sharp change in several geophysical field characteristics. To study these characteristics and their relationship with the distribution of earthquakes and faults in the study area, we first analyze the spatial gravity anomaly to achieve the Bouguer gravity anomaly(EGM2008 BGA) and the regional gravity survey Bouguer gravity anomaly.Next, we ascertain the Moho depth and crustal thickness of the study area using interface inversion with the control points derived from the seismic and magnetotelluric sounding profiles achieved in recent years. In this paper, we summarize the relief, trend, Moho gradient, and crustal nature, in addition to their relationship with the distribution of earthquakes and faults in the study area. The findings show that earthquakes with magnitudes greater than Ms7.0 are mainly distributed in the Moho Bouguer anomaly variation belt and faults. The results of the study are important for future research on tectonic characteristics, geological and geophysical surveys, and seismicity patterns. | Wu Guiju Tan Hongbo Zou Zhengbo Yang Guangliang Shen Chongyang | 2015 | Geodesy and Geodynamics2015，6，3： | 4 |
| 8 | Strengthening population medicine to promote public health显示文摘As we enter.2022,we are facedwith the fact that coronavirus disease2019(CovID-19)has been devastating the world formore than 2full years.Since the original outbreak of COVID-19in December2019,the disease has proved to be a major threat to global health and,perhaps more importantly,one that is not likely to be resolved soon.Severe_acute respiratory syndrome coronavirus. | Chen Wang Simiao Chen Guangliang Shan Zhiwei Leng Till Bärnighausen Weizhong Yang | 2022 | Chinese Medical Journal2022，，10： | 3 |
| 9 | Color image detail enhancement based on quaternion guided filter显示文摘Color image enhancement is an active research field in image processing. Currently, many image enhancement methods are capable of enhancing the details of the color image. However, these methods only process the red, green and blue(RGB) color channels separately, which leads to color distortion easily. In order to overcome this problem, the paper presents an approach to integrate the quaternion theory into the traditional guided filter to obtain a quaternion guided filter(QGF). This method makes full use of the color information of an image to realize the holistic processing of RGB color channels. So as to preserve color information while enhancing details, this paper proposes a color image detail enhancement algorithm based on the QGF. Experimental results show that the proposed algorithm is effective in the applications of the color image detail enhancement, and enables image's edges to be more prominent and texture clearer while avoiding color distortion. Compared with the existing image enhancement methods, the proposed method achieves better enhancement performance in terms of the visual quality and the objective evaluating indicators. | Wu Kun Li Guiju Han Guangliang Yang Hang Liu Peixun | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，4： | 3 |
| 10 | Temporal gravity changes before the 2008 Yutian Ms7.3 earthquake显示文摘Based on the data of the repeated gravity observation network in Chinese mainland since 1998,we analyzed the temporal changes of regional gravity field before the 2008 Yutian Ms7.3 earthquake.The result shows some mid-to-long term(two to ten years)changes during the earthquake's preparation.Notable features are a gravity increase lasting several years and a relatively large-scaled gradient zone of gravity change,the former indicating a continuous energy accumulation and the latter a possible location of seismic rupture.These gravity changes showed a trend of increase-accelerated increase-decelerated increase,similar to that of the Tangshan Ms7.8 earthquake in 1976.The maximum accumulated gravity change related to the earthquake reached 200×10-8 ms-2. | Shen Chongyang Li Hui Sun Shaoan Yang Guangliang Xuan Songbai Tan Hongbo Liu Shaoming | 2012 | Geodesy and Geodynamics2012，3，1： | 3 |
| 11 | Correlation analysis and partial least square modeling to quantify typical minerals with Chang'E-3 visible and near-infrared imaging spectrometer's ground validation data显示文摘In 2013, Chang'E-3 program will develop lunar mineral resources in-situ detection. A Visible and Near-infrared Imaging Spectrometer(VNIS) has been selected as one payload of CE-3 lunar rover to achieve this goal. It is critical and urgent to evaluate VNIS' spectrum data quality and validate quantification methods for mineral composition before its launch. Ground validation experiment of VNIS was carried out to complete the two goals, by simulating CE-3 lunar rover's detection environment on lunar surface in the laboratory. Based on the hyperspectral reflectance data derived, Correlation Analysis and Partial Least Square(CA-PLS) algorithm is applied to predict abundance of four lunar typical minerals(pyroxene, plagioclase, ilmenite and olivine) in their mixture. We firstly selected a set of VNIS' spectral parameters which highly correlated with minerals' abundance by correlation analysis(CA), and then stepwise regression method was used to find out spectral parameters which make the largest contributions to the mineral contents. At last, functions were derived to link minerals' abundance and spectral parameters by partial least square(PLS) algorithm. Not considering the effect of maturity, agglutinate and Fe0, we found that there are wonderful correlations between these four minerals and VNIS' spectral parameters, e.g. the abundance of pyroxene correlates positively with the mixture's absorption depth, the value of absorption depth added as the increasing of pyroxene's abundance. But the abundance of plagioclase correlates negatively with the spectral parameters of band ratio, the value of band ratio would decrease when the abundance of plagioclase increased. Similar to plagioclase, the abundance of ilmenite and olivine has a negative correlation with the mixture's reflectance data, if the abundance of ilmenite or olivine increase, the reflectance values of the mixture will decrease. Through model validation, better estimates of pyroxene, plagioclase and ilmenite's abundances are given. It is concluded that VNIS has the capability to be applied on lunar minerals' identification, and CA-PLS algorithm has the potential to be used on lunar surface's in-situ detection for minerals' abundance prediction. | LIU Bin LIU Jianzhong ZHANG Guangliang LING Zongcheng ZHANG Jiang HE Zhiping YANG Benyong ZOU Yongliao | 2014 | Chinese Journal Of Geochemistry2014，33，1： | 3 |
| 12 | Engineering of tungsten carbide nanoparticles for imaging-guided single 1,064 nm laser-activated dual-type photodynamic and photothermal therapy of cancer显示文摘光力学的治疗(太平洋夏季时间) 的有希望的潜力为癌症治疗造成了最低限度地侵略的治疗学的途径的发展。然而,在 hypoxic 肿瘤环境和轻穿入深度在太平洋夏季时间功效克服限制仍然是挑战。我们报导钨碳化物 nanoparticles 的工程(W 2 C NP ) 为 1,064 nm 激活激光的双类型的太平洋夏季时间和联合 theranostics。综合 W 2 C NP 允许双类型的反应的氧种类的柔韧的产生,包括氢氧根激进分子(类型我) 并且汗衫氧(类型 II ) ,用仅仅挑选 1,064 nm 激光激活,甚至在 hypoxic 肿瘤的创新有效太平洋夏季时间环境。W 2 C NP 也在 1,064 nm 激光照耀下面拥有高 photothermal 性能,这样创新的 synergistically 提高的癌症太平洋夏季时间和 photothermal 治疗的治疗学的功效。另外, photoacoustic 和 X 光检查计算了 W 2 C NP 便于肿瘤诊断和治疗的集成。发达 W 2 C 基于 theranostic nanoagents 在 hypoxic 肿瘤增加反应的氧种类的产生,改进轻穿入深度,并且便于联合 photothermal 治疗和 photoacoustic/computed 断层摄影术双模式的 bioimaging。这些属性能为先进生物医学的应用程序刺激转变金属碳化物的探索。 | Shi-Hua Li Wen Yang Yang Liu Xiao-Rong Song Rui Liu Guangliang Chen Chun-Hua Lu Huang-Hao Yang | 2018 | Nano Research2018，11，9： | 2 |
| 13 | Joint inversion of gravity and seismic data along a profile across the seismogenic fault of 2010 Yushu Ms7. 1 earthquake显示文摘Yushu Ms7. 1 earthquake occurred on the Ganzi-Yushu fault zone,across which we carried out a joint relative-gravity and seismic-reflection survey,and then performed a gravity inversion constrained by the seismic-reflection result. Based on the data of complete Bouguer gravity anomaly and seismic reflection,we obtained a layered interface structure in deep crust down to Moho. Our study showed that the inversion could reveal the interfaces of strata along the survey profile and the directions of regional faults in two-dimension. From the characteristics of the observed topography of the Moho basement,we tentatively confirmed that the uplift of eastern edge of Qinghai-Tibet plateau was caused by the subduction of the Indian plate. | Yang Guangliang Wang Fuyun Shen Chongyang Sun Shaoan Tan Hongbo | 2011 | Geodesy and Geodynamics2011，2，4： | 2 |
| 14 | Research on the relationship between geophysical structural features and earthquakes in Mid-Yunnan and the surrounding area显示文摘In this study,we analyzed the gravity and,magnetic characteristics,and the occurrence of a fault zone and discussed the relationships between the two locations.The results reveal that the subsurface structures strikes are different compared with those in the research region.In other words,the geophysical advantageous directions from the gravity and magnetic anomalies are not the same as those caused by the surface structures.The local horizontal gradient results from the gravity and magnetic anomalies show that the majority of earthquakes occur along an intense fault zone,which is a zone of abrupt gravity and negative magnetic change,where the shapes match very well.From the distribution of earthquakes in this area,we find that it has experienced more than 11 earthquake events with magnitude larger than Ms7.0.In addition,water development sites such as Jinshajiang,Lancangjiang,and the Red River and Pearl River watersheds have been hit ten times by earthquakes of this magnitude.It is observed that strong earthquakes occur frequently in the Holocene active fault zone. | Wu Guiju Tan Hongbo Yang Guangliang Shen Chongyang | 2015 | Geodesy and Geodynamics2015，6，5： | 1 |
| 15 | Wenchuan Ms8.0 earthquake coseismic slip distribution inversion显示文摘By using GPS and gravity data before and after the Wenchuan Ms8.0 earthquake and combining data from geological surveys and geophysical inversion studies, an initial coseismic fault model is constructed. The dip angle changes of the fault slip distribution on the fault plane are inversed, and the inversion results show that the shape of the fault resembles a double-shovel. The Yingxiue Beichuan Fault is approximately 330 km long, the surface fault dip angle is 65.1, which gradually reduces with increasing depth to 0 at the detachment layer at a depth of 19.62 km. The Guanxiane Jiangyou Fault is approximately90 km long, and its dip angle at the surface is 55.3, which gradually reduces with increasing depth; the fault joins the Yingxiue Beichuan Fault at 13.75 km. Coseismic slip mainly occurs above a depth of 19 km. There are five concentrated rupture areas, Yingxiu,Wenchuan, Hanwang, Beichuan, and Pingwu, which are consistent with geological survey results and analyses of the aftershock distribution. The rupture mainly has a thrust component with a small dextral strikeeslip component. The maximum slip was more than10 m, which occurred near Beichuan and Hanwang. The seismic moment is 7.84 1020 Nm(Mw7.9), which is consistent with the seismological results. | Tan Hongbo Wu Guiju Xuan Songbai Yang Guangliang Fan Wenhua Shen Chongyang | 2015 | Geodesy and Geodynamics2015，6，3： | 1 |
| 16 | A novel doppler frequency offset estimation method for DVB-T system in HST environment 显示文摘 | Yang Lihua Ren Guangliang Qiu Zhiliang | 2012 | IEEE Transactions on Broadcast- ing2012，58，1： | 1 |
| 17 | A transient protection scheme for HVDC transmission line显示文摘 | Zheng Xiaodong Nengling Tai Guangliang Yang | 2012 | IEEE Transactions on Power Delivery2012，27，2： | 1 |
| 18 | The effects of current density on the plase composition and microstructure properties of micro- arc oxidation coating 显示文摘 | Yang Guangliang Lu Xianyi Bai Yizhen | 2002 | Journal of Alloys and Compounds2002，345，47： | 1 |
| 19 | The Effect Density on the Phase composition and Microstructure Properties of Micro-Arc Oxidation Coating显示文摘 | Yang Guangliang Lü Xianyi Bai Yizhen | 2002 | Journal of Alloys and Compounds2002，345，1： | 1 |
| 20 | The effects of current density on the phase composition and microstructure properties of micro- arc oxidation coating显示文摘 | Yang Guangliang Lu Xianyi Bai Yizhen | 2002 | Journal of Alloys and Compounds2002，345，1： | 1 |
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