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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Qi-Qin Accretionary Belt in Central China Orogen: accretion by trench jam of oceanic plateau and formation of intra-oceanic arc in the Early Paleozoic Qin-Qi-Kun Ocean显示文摘Most orogenic belts have experienced a complex accretionary process with multiple episodes of sea?oor subduction and trench retreat.This accretionary process is important in continenta development and growth[1,2].Three giant orogens extend in China,e.g.,the Central Asian Orogen in the north,the Central China Orogen in the middle and the Himalayan Orogen in the southwest.They are keys for the formation of the Eurasian continent(Fig.1a).The Central China Orogen | Shuguang Song Liming Yang Yuqi Zhang Yaoling Niu Chao Wang Li Su Yanlin Gao | 2017 | Science Bulletin2017，62，15： | 28 |
| 3 | Constructal design progress for eight types of heat sinks显示文摘This review paper summarizes constructal design progress performed by the authors for eight types of heat sinks with ten performance indexes being taken as the optimization objectives,respectively,by combining the methods of theoretical analysis and numerical calculation.The eight types of heat sinks are uniform height rectangular fin heat sink,non-uniform height rectangular fin heat sink,inline cylindrical pin-fin heat sink(ICPHS),plate single-row pin fin heat sink(PSRPHS),plate inline pin fin heat sink(PIPHS),plate staggered pin fin heat sink(PSPHS),single-layered microchannel heat sink(SLMCHS)with rectangular cross sections and double-layered microchannel heat sink(DLMCHS)with rectangular cross sections,respectively.And the ten performance indexes are heat transfer rate maximization,maximum thermal resistance minimization,minimization of equivalent thermal resistance which is defined based on the entransy dissipation rate(equivalent thermal resistance for short),field synergy number maximization,entropy generation rate minimization,operation cost minimization,thermo-economic function value minimization,pressure drop minimization,enhanced heat transfer factor maximization and efficiency evaluation criterion number maximization,respectively.The optimal constructs of the eight types of heat sinks with different constraints and based on the different optimization objectives are compared with each other.The results indicated that the optimal constructs mostly are different based on different optimization objectives under the same boundary condition.The optimization objective should be suitable chosen based on the focus when the constructal design for one heat sink is performed.The results obtained herein have some important theoretical significances and application values,and can provide scientific bases and theoretical guidelines for the thermal design of real heat sinks and their applications. | CHEN LinGen YANG AiBo FENG HuiJun GE YanLin XIA ShaoJun | 2020 | Science China(Technological Sciences)2020，63，6： | 25 |
| 4 | A distributed scheme developed for eco-hydrological modeling in the upper Heihe River显示文摘Modeling the hydrological processes at catchment scale requires a flexible distributed scheme to represent the catchment topography,river network and vegetation pattern.This study has developed a distributed scheme for eco-hydrological simulation in the upper Heihe River.Based on a 1 km×1 km grid system,the study catchment is divided into 461 sub-catchments,whose main streams form the streamflow pathway.Furthermore,a 1 km grid is represented by a number of topographically similar'hillslope-valley'systems,and the hillslope is the basic unit of the eco-hydrological simulation.This model is tested with a simplified hydrological simulation focusing on soil-water dynamics and streamflow routing.Based on a 12-year simulation from 2001 to 2012,it is found that variability in hydrological behavior is closely associated with climatic and landscape conditions especially vegetation types.The subsurface and groundwater flows dominate the total river runoff.This implies that the soil freezing and thawing process would significantly influence the runoff generation in the upper Heihe basin.Furthermore,the runoff components and water balance characteristics vary among different vegetation types,showing the importance of coupling the vegetation pattern into catchment hydrological simulation.This paper also discusses the model improvement to be done in future study. | YANG DaWen GAO Bing JIAO Yang LEI Hui Min ZHANG YanLin YANG HanBo CONG ZhenTao | 2015 | Science China Earth Sciences2015，58，1： | 20 |
| 5 | Autophagy in Atherosclerosis: A Phenomenon Found in Human Carotid Atherosclerotic Plaques显示文摘 | Huihui Liu Yongjun Gag Tong Tong Jijun Shi Yanlin Zhang Yaping Yang Chunfeng Liu | 2015 | Chinese Medical Journal2015，，1： | 16 |
| 6 | Reactivation of γ-globin expression through Cas9 or base editor to treat β-hemoglobinopathies显示文摘Dear Editor,Mutations in the β-globin gene,the essential component of adult hemoglobin(HbA;a2p2),results in either a production of aberrant sickle hemoglobin(HbS)leading to sickle cell disease(SCD)or an insufficient β-globin synthesis leading to β-thalassemia.These two major forms of β-hemoglobinopathies cause impaired erythropoiesis and life-threatening anemia.Clinical evidence has suggested that reaaivation of fetal γ-globin(HBG)gene expression which is normally silenced after birth by certain genetic mutations can ameliorate the clinical course of β-hemoglobinopathies. | Liren Wang Linxi Li Yanlin Ma Handan Hu Qi Li Yang Yang Wenbang Liu Shuming Yin Wei Li Bin Fu Ryo Kurita Yukio Nakamura Mingyao Liu Yongrong Lai Dali Li | 2020 | Cell Research2020，30，3： | 14 |
| 7 | Association of miR-502-binding site single nucleotide polymorphism in the 3'-untranslated region of SET8 and TP53 codon 72 polymorphism with non-small cell lung cancer in Chinese population显示文摘这研究的目的是识别是否在 3-untranslated 区域( 3-UTR )的 miR-502-binding 地点单身者核苷酸多型性( SNP )使蛋白质 8 包含域( SET8 )并且肿瘤蛋白质 p53 ( TP53 ) codon 72 多型性为非小的房间肺癌症与风险被联系( NSCLC ),独立地或联合,在从南部的汉的中国人民之中。SET8 和 TP53 codon 的遗传型外部血 DNA 的 72 多型性用在 164 个 NSCLC 盒子和 199 控制上在 casecontrol 研究定序的聚合酶链反应限制碎片长度多型性和直接 DNA 被检测。SET8 TT (机会比率,或 = 2.173, 95% 信心间隔, CI = 1.0454.517 ) 或 TP53 GG (或 = 2.579, 95% CI = 1.3664.870 ) 遗传型被分别地与 SET8 CC 或 TP53 CC 遗传型作比较与 NSCLC 的增加的风险联系。类似的结果在 SET8 后退的模型被获得(或 = 2.074, 95% CI = 1.0194.221, P < 0.05 ) ,并且 TP53 codon 的主导、后退的模型 72 被执行,分别地(或 = 1.809, 95% CI = 1.1592.825, P < 0.05;或 = 1.933, 95% CI = 1.0963.409, P < 0.05 ) 。另外,在 SET8 和 TP53 多型性之间的相互作用增加了 NSCLC 的风险在一多样地举止,与 OR 是 3.032 (95%CI = 1.5805.816 ) 为带 SET8 TT 和 TP53 GG 遗传型的题目。因此,在 SET8 和 TP53 codon 的 3-UTR 的 miR-502-binding 地点 SNP 72 多型性可以是到在中国人口的 NSCLC 的基因危险性的标记,并且在 NSCLC 的发生有一个可能的 genegene 相互作用。 | Shaodi Yang Haiyan Guo Benjie Wei Shengcui Zhu Yanlin Cai Pei Jiang Jianxin Tang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，2： | 12 |
| 8 | Prevalence of Metabolic Syndrome and Risk Factors Among Chinese Adults:Results from a Population-Based Study—Beijing,China,2017–2018显示文摘Summary What is already known about this topic?Metabolic syndrome(MetS)is one of the most easily available health indicative markers for cardiovascular diseases,and it has become a major public health problem worldwide due to increasing urbanization and aging populations.The prevalence of MetS increased dramatically in China,however,there are no records of MetS defined by the 2017 Chinese Diabetes Society for Beijing by far.What is added by this report?In this study,the data of 24,412 participants aged 18–74 years from a large population-based study in Beijing was collected.The overall prevalence of MetS among Beijing residents was 24.5%.The prevalence was 35.2%in males and 15.4%in females.What are the implications for public health practice?Effective public health strategies should target males,people with older age,lower education,higher body mass index,smokers,those who drink alcohol,those who are unemployed or retired,and those who live in rural areas on MetS prevention and control. | Jufen Liu Qingping Liu Zhiwen Li Jing Du Chao Wang Yanlin Gao Zaihua Wei Jing Wang Yunping Shi Jianting Su Yang Liu Ping Wang Chunyan Xie Gang Li Bing Shao Le Zhang | 2022 | China CDC weekly2022，4，29： | 4 |
| 9 | Abscisic acid receptors maintain abscisic acid homeostasis by modulating UGT71C5 glycosylation activity显示文摘Uridine diphosphate-glucosyltransferases(UGTs)maintain abscisic acid(ABA)homeostasis in Arabidopsis thaliana by converting ABA to abscisic acid-glucose ester(ABA-GE).UGT71C5 plays an important role in the generation of ABA-GE.Abscisic acid receptors are crucial upstream components of the ABA signaling pathway,but how UGTs and ABA receptors function together to modulate ABA levels is unknown.Here,we demonstrated that the ABA receptors RCAR12/13 and UGT71 C5 maintain ABA homeostasis in Arabidopsis following rehydration under drought stress.Biochemical analyses show that UGT71C5 directly interacted with RCAR8/12/13 in yeast cells,and the interactions between UGT-71C5 and RCAR12/13 were enhanced by ABA treatment.Enzyme activity analysis showed that ABA-GE contents were significantly elevated in the presence of RCAR12 or RCAR13,suggesting that these ABA receptors enhance the activity of UGT71C5.Determination of the content of ABA and ABA-GE in Arabidopsis following rehydration under drought stress revealed that ABA-GE contents were significantly higher in Arabidopsis plants overexpressing RCAR12 and RCAR13 than in nontransformed plants and plants overexpressing RCAR11 following rehydration under drought stress.These observations suggest that RCAR12 and RCAR13 enhance the activity of UGT71C5 to glycosylate excess ABA into ABA-GE following rehydration under drought stress,representing a rapid mechanism for regulating plant growth and development. | Yanlin Ma Jing Cao Qiaoqiao Chen Jiahan He Zhibin Liu Jianmei Wang Xufeng Li Yi Yang | 2021 | Journal of Integrative Plant Biology2021，63，3： | 3 |
| 10 | Small changes in the length of diselenide bond-containing linkages exert great influences on the antitumor activity of docetaxel homodimeric prodrug nanoassemblies显示文摘Homodimeric prodrug-based self-assembled nanoparticles,with carrier-free structure and ultrahigh drug loading,is drawing more and more attentions.Homodimeric prodrugs are composed of two drug molecules and a pivotal linkage.The influence of the linkages on the self-assembly,in vivo fate and antitumor activity of homodimeric prodrugs is the focus of research.Herein,three docetaxel(DTX)homodimeric prodrugs are developed using different lengths of diselenide bond-containing linkages.Interestingly,compared with the other two linkages,the longest diselenide bond-containing linkage could facilitate the self-delivery of DTX prodrugs,thus improving the stability,circulation time and tumor targeting of prodrug nanoassemblies.Besides,the extension of linkages reduces the redox-triggered drug release and cytotoxicity of prodrug nanoassemblies in tumor cells.Although the longest diselenide bond-containing prodrug nanoassemblies possessed the lowest cytotoxicity to 4T1 cells,their stable nanostructure maintained intact during circulation and achieve the maximum accumulation of DTX in tumor cells,which finally“turned the table”.Our study illustrates the crucial role of linkages in homodimeric prodrugs,and gives valuable proposal for the development of advanced nano-DDS for cancer treatment. | Lingxiao Li Shiyi Zuo Fudan Dong Tian Liu Yanlin Gao Yinxian Yang Xin Wang Jin Sun Bingjun Sun Zhonggui He | 2021 | Asian Journal of Pharmaceutical Sciences2021，16，3： | 3 |
| 11 | Recent Progress in Atmospheric Chemistry Research in China: Establishing a Theoretical Framework for the “Air Pollution Complex”显示文摘Atmospheric chemistry research has been growing rapidly in China in the last 25 years since the concept of the“air pollution complex”was first proposed by Professor Xiaoyan TANG in 1997.For papers published in 2021 on air pollution(only papers included in the Web of Science Core Collection database were considered),more than 24000 papers were authored or co-authored by scientists working in China.In this paper,we review a limited number of representative and significant studies on atmospheric chemistry in China in the last few years,including studies on(1)sources and emission inventories,(2)atmospheric chemical processes,(3)interactions of air pollution with meteorology,weather and climate,(4)interactions between the biosphere and atmosphere,and(5)data assimilation.The intention was not to provide a complete review of all progress made in the last few years,but rather to serve as a starting point for learning more about atmospheric chemistry research in China.The advances reviewed in this paper have enabled a theoretical framework for the air pollution complex to be established,provided robust scientific support to highly successful air pollution control policies in China,and created great opportunities in education,training,and career development for many graduate students and young scientists.This paper further highlights that developing and low-income countries that are heavily affected by air pollution can benefit from these research advances,whilst at the same time acknowledging that many challenges and opportunities still remain in atmospheric chemistry research in China,to hopefully be addressed over the next few decades. | Tong ZHU Mingjin TANG Meng GAO Xinhui BI Junji CAO Huizheng CHE Jianmin CHEN Aijun DING Pingqing FU Jian GAO Yang GAO Maofa GE Xinlei GE Zhiwei HAN Hong HE Ru-Jin HUANG Xin HUANG Hong LIAO Cheng LIU Huan LIU Jianguo LIU Shaw Chen LIU Keding LU Qingxin MA Wei NIE Min SHAO Yu SONG Yele SUN Xiao TANG Tao WANG Tijian WANG Weigang WANG Xuemei WANG Zifa WANG Yan YIN Qiang ZHANG Weijun ZHANG Yanlin ZHANG Yunhong ZHANG Yu ZHAO Mei ZHENG Bin ZHU Jiang ZHU | 2023 | Advances in Atmospheric Sciences2023，40，8： | 2 |
| 12 | Establishment of an Organic Model of SMC Proliferation with Cultured Aorta of Rats显示文摘 | Yanlin Zhang Caiying Wang Qin Yang Gang Yang Kaiyun Wu Ya 'an Yang | 2006 | Journal of US-China Medical Science2006，3，3： | 2 |
| 13 | Pool Sizes and Turnover of Soil Organic Carbon of Farmland Soil in Karst Area of Guilin显示文摘The three-pool and first-order model separates the mineralizable organic carbon into active,slow,and passive carbon pools.This paper used the model and decomposition curves of the soil organic carbon to fit the active pool and its decomposition rate,slow pool and its decomposition rate.The results showed that the size of the active pool from different profiles accounted for 2.09%-3.08% of the total soil organic carbon and the mean residue time was 3.57-17.21 days.And the size of the slow pool accounted for 3.19%-43.55% and the mean residue time was 1.12-4.94 years.Acid hydrolysis(6M HCl) was used to fractionate the passive organic carbon,which accounted for 50.83%-94.44% of the total soil organic carbon. | YANG Hui CAO Jianhua ZHANG Liankai HOU Yanlin MAO Lifeng | 2011 | Journal of Northeast Agricultural University(English Edition)2011，18，1： | 2 |
| 14 | Comparing community birdwatching and professional bird monitoring with implications for avian diversity research: a case study of Suzhou, China显示文摘Background:In the past decades,birdwatching as a hobby developed rapidly and produced ample scientific records that have aided conservation efforts.Therefore,it is increasingly attractive to promote avian research by providing data from birdwatching.Methods:We compared records from 16 years of community birdwatching and a 1-year formalized bird monitoring in Suzhou,China to study the similarities and differences between the two monitoring methods.Results:We showed that within the 325 bird species recorded by the two methods,an annual average of 108 species were documented by community science and 223 bird species were recorded by 1-year formalized monitoring.Measured by the number of bird species recorded per survey trip,the bird monitoring activity of community birdwatchers was significantly lower.Furthermore,the monitoring intensity of community birdwatching measured as the average survey trips per site each survey year was also lower than that of formalized bird monitoring.In addition,community birdwatchers preferred urban landscapes to rural areas.Conclusions:Community birdwatching could record the majority of local birds and complements the professional surveys in avian research.Well designed and coordinated community science can be used to expand the knowledge about avian distribution and population dynamics.These findings are critical for the development of conservation science with regard to community involvement. | Yan Zhou Anping Chen Jenny QOuyang Yanlin Liu Aiyu Zheng Zaixi Yang Yong Zhang Bin Wang Yifei Jia Shengwu Jiao Qing Zeng Changhu Lu | 2020 | Avian Research2020，11，2： | 2 |
| 15 | The molecular conformation of silk fibroin regulates osteogenic cell behavior by modulating the stability of the adsorbed protein-material interface显示文摘Silk fibroin(SF)can be used to construct various stiff material interfaces to support bone formation.An essential preparatory step is to partially transform SF molecules from random coils toβ-sheets to render the material water insoluble.However,the influence of the SF conformation on osteogenic cell behavior at the material interface remains unknown.Herein,three stiff SF substrates were prepared by varying theβ-sheet content(high,medium,and low).The substrates had a comparable chemical composition,surface topography,and wettability.When adsorbed fibronectin was used as a model cellular adhesive protein,the stability of the adsorbed protein-material interface,in terms of the surface stability of the SF substrates and the accompanying fibronectin detachment resistance,increased with the increasingβ-sheet content of the SF substrates.Furthermore,(i)larger areas of cytoskeleton-associated focal adhesions,(ii)higher orders of cytoskeletal organization and(iii)more elongated cell spreading were observed for bone marrow-derived mesenchymal stromal cells(BMSCs)cultured on SF substrates with high vs.lowβ-sheet contents,along with enhanced nuclear translocation and activation of YAP/TAZ and RUNX2.Consequently,osteogenic differentiation of BMSCs was stimulated on highβ-sheet substrates.These results indicated that theβ-sheet content influences osteogenic differentiation of BMSCs on SF materials in vitro by modulating the stability of the adsorbed protein-material interface,which proceeds via protein-focal adhesion-cytoskeleton links and subsequent intracellular mechanotransduction.Our findings emphasize the role of the stability of the adsorbed protein-material interface in cellular mechanotransduction and the perception of stiff SF substrates with differentβ-sheet contents,which should not be overlooked when engineering stiff biomaterials. | Yanlin Long Xian Cheng John A.Jansen Sander G.C.Leeuwenburgh Jing Mao Fang Yang Lili Chen | 2021 | Bone Research2021，9，2： | 1 |
| 16 | Bioinspired molecules design for bilateral synergistic passivation in buried interfaces of planar perovskite solar cells显示文摘Trap-mediated energy loss in the buried interface with non-exposed feature constitutes one of the serious challenges for achieving high-performance perovskite solar cells(PSCs).Inspired by the adhesion mechanism of mussels,herein,three catechol derivatives with functional Lewis base groups,namely 3,4-Dihydroxyphenylalanine(DOPA),3,4-Dihydroxyphenethylamine(DA)and 3-(3,4-Dihydroxyphenyl)propionic acid(DPPA),were strategically designed.These molecules as interfacial linkers are incorporated into the buried interface between perovskite and SnO_(2) surface,achieving bilateral synergetic passivation effect.The crosslinking can produce secondary bonding with the undercoordinated Pb^(2+) and Sn^(4+) defects.The PSCs treated with DOPA exhibited the best performance and operational stability.Upon the DOPA passivation,a stabilized power conversion efficiency(PCE)of 21.5%was demonstrated for the planar PSCs.After 55 days of room-temperature storage,the unencapsulated devices with the DOPA crosslinker could still maintain 85%of their initial performance in air under relative humidity of-15%.This work opens up a new strategy for passivating the buried interfaces of perovskite photovoltaics and also provides important insights into designing defect passivation agents for other perovskite optoelectronic devices,such as light-emitting diodes,photodetectors,and lasers. | Bin Wang Junjie Ma Zehua Li Gangshu Chen Qiang Gu Shuyao Chen Yiqiang Zhang Yanlin Song Jingbo Chen Xiaodong Pi Xuegong Yu Deren Yang | 2022 | Nano Research2022，15，2： | 1 |
| 17 | Synthesisand characterization of a novel metal-organic compound:9,10-dihydro-9-oxa-phosphaphenanthrene 10-oxide(DOPO)-Mg显示文摘 | Liu Yanlin Zou Meishuai Yang Rongjie | 2015 | Chem Letter2015，44，6： | 1 |
| 18 | Study on release rate of latent heat in Czochralski silicon growth显示文摘The pulling rate in czochralski silicon (CZSi) growth is important for reducing the cost of solar cell. In this paper, double-heater, heat shield and composite argon duct system were introduced in the Ф450 mm hot zone of a Czochralski furnace. The pulling rate under different thermal system was recorded in experiments. Argon flow and temperature fields were simulated by finite element method(FEM). Experimental results and numerical simulation indicate that double-heater and composite argon duct system can enhance obviously the release rate of latent heat. In Φ 200 mm Czochralski silicon (CZSi) growth, average pulling rate can increase from 0.6 mm·min-1 in the conventional hot zone to 0.8 mm·min-1 in the modified hot zone. | REN Bingyan YANG Jiankun LI Yanlin LIU Xiaoping WANG Minhua | 2006 | Rare Metals2006，25，z2： | 1 |
| 19 | Facile pathway to generate agrochemical nanosuspensions integrating super-high load, eco-friendly excipients, intensified preparation process, and enhanced potency显示文摘An aqueous nanosuspension of agrochemicals unlike pharmaceutics has to achieve massive production in an effective way,capable to ensure sufficient profits in commercialization.This work implements the flash nanoprecipitation(FNP)technique to effectively generate agrochemical nanosuspension,anticipatedly overcoming such an obstacle.Azoxystrobin,a broad spectrum fungicide,in either acetone or ethanol is used herein as a mode agrochemical.To ensure a green and practical utilization,three kinds of commercially available and eco-friendly surfactants,i.e.,poly(ethylene glycol)-block-poly(lactic-co-glycolic acid)(PEG-b-PLGA),Tween 80 and alkyl polyglucosides(APGs),are employed for stabilizing the nanoparticles.The results show that the polymeric stabilizer,PEG-b-PLGA,has the best stabilization efficiency,and can maintain the particles below 100 nm for at least three weeks.The azoxystrobin load of the nanoparticles reaches as high as 77 wt.%,beneficial to enhancing the biological potency.Moreover,the FNP brings the particles a much smaller size,narrower size distribution,better size stability,and higher biological efficacy than the ones made via a traditional method of the drop and stir(DS).The nanosuspensions present superior fungicidal performances over a prevailing counterpart from Syngenta.This study proves an enhanced biological potency and reduced dosage of agrochemical nanosuspension made via the FNP,indicating a remarkable advantage of the FNP over the conventional preparation.The integration of a super-high load,eco-friendly excipients,intensified preparation process,enhanced potency,and reduced dosage creates a promising pathway to generate a green aqueous nanosuspension of agrochemicals. | Zhengxi Zhu Chuanhua Shao Yanlin Guo Jianguo Feng Chong Chen and Haibin Yang | 2021 | Nano Research2021，14，7： | 1 |
| 20 | Experimental studies on histocompatibility of there bio-derived bones显示文摘 | Yang Zhiming Li Yanlin Xie Huiqi | 2002 | Chin J Plast Surg2002，18，1： | 1 |
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