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| 1 | Sewage irrigation increased methane and nitrous oxide emissions from rice paddies in southeast China显示文摘 | Jianwen Zou Shuwei Liu Yanmei Qin Genxing Pan Dawei Zhu | 2008 | Agriculture, Ecosystems and Environment2008，，4： | 2 |
| 2 | 吉非替尼对晚期非小细胞肺癌患者生活质量的改善(英文)显示文摘Objective:The aim of this study was to evaluate the effect of gefitinib on improvement of quality of life (QoL) of patients with advanced non-small cell lung cancer (NSCLC). Methods:There were 70 patients with advanced NSCLC. One oral gefitinib tablet (250 mg) was administered every day without interruption unless disease progression or unacceptable toxicity occurred. The impact of treatment on disease-related symptoms and QoL was evaluated with the Chinese versions of European Organization for Research and Treatment of Cancer Quality of Life Questionnaires (EORTC QLQ-C30 and QLQ-LC13). Results: Fifty-eight patients had finished the questionnaires. The mean scores of five functioning scales (physical, role, emotional, cognitional and social) were 62.64, 56.03, 68.41, 64.67, 60.63 respectively after eight weeks of treatment, which were 52.30, 49.43, 64.39, 59.79, 52.30 respectively before treatment, and the mean score of global QoL after and before treatment was 60.17 and 52.70 respectively. There was statistical difference in five functioning scales and global QoL (P < 0.05). Mean scores of main general symptoms (fatigue and appetite loss) were 57.66 and 48.08 respectively after eight weeks of treatment, which were 61.11 and 51.72 respectively before treatment, and mean scores of disease-related symptoms (dyspnoea, coughing, empsyxis, pain in chest) were 48.66, 47.13, 26.82, 24.71 respectively after eight weeks of treatment, which were 54.98, 53.64, 27.78, 28.54 respectively before treatment. There was statistical difference in fatigue, dyspnoea, cough and pain in chest (P < 0.05). Response rate of five functioning and global QoL were all more than 50% after gefitinib treatment. Response rate of main general symptoms and disease-related symptoms were all more than 40%. QoL and symptom response correlated with disease control. The patients with better QoL had longer survival. Conclusion: gefitinib treatment can improve the QoL and symptoms of advanced NSCLC patients. | Yanmei Zou Hua Xiong Shiying Yu | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，9： | 2 |
| 3 | Modeling interannual variability of global soil respiration from climate and soil properties显示文摘 | Shutao Chen Yao Huang Jianwen Zou Qirong Shen Zhenghua Hu Yanmei Qin Haishan Chen Genxing Pan | 2010 | Agricultural and Forest Meteorology2010，，4： | 2 |
| 4 | Pressureless densification and mechanical properties of hafnium diboride doped with B4C:From solid state sintering to liquid phase sintering显示文摘 | Zou Ji Zhang Guojun Kan Yanmei | | 0，，30： | 1 |
| 5 | Effects of water regime during rice-growing season on annual direct N 2 O emission in a paddy rice–winter wheat rotation system in southeast China显示文摘 | Shuwei Liu Yanmei Qin Jianwen Zou Qiaohui Liu | 2009 | Science of the Total Environment2009，，4： | 1 |
| 6 | Pressure- less densification and mechanical properties of hafnium diboride doped with B4C: from solid state sintering to liquid phase sintering 显示文摘 | Ji Zou Zhang GuoJun Kan Yanmei | 2010 | Journal of the European Ceramic Society2010，，30： | 1 |
| 7 | Sewage in-igation increased methane and nitrous oxide emissions from riee paddies in southeast China显示文摘 | Zou Jianwen Lit Shuwei Qin Yanmei | 2009 | Agriculture Ecosystems and Environment2009，129，： | 1 |
| 8 | Sewage irrigation increased methane and nitrous oxide emissions from rice paddies in southeast China显示文摘 | Jianwen Zou Shuwei Liu Yanmei Qin Genxing Pan Dawei Zhu | 2009 | Agricuhure Ecosystems and Environment2009，129，4： | 1 |
| 9 | Sewage irrigation increased methane and nitrous oxide emissions from rice paddies in southeast China显示文摘 | Zou Jianwen Liu Shuwei Qin Yanmei | 2009 | Agriculture Ecosystems and Environment2009，129，4： | 1 |
| 10 | Effects of water regime during rice-growing season on annual direct N 2 O emission in a paddy rice–winter wheat rotation system in southeast China显示文摘 | Shuwei Liu Yanmei Qin Jianwen Zou Qiaohui Liu | 2009 | Science of the Total Environment2009，，4： | 1 |
| 11 | Effects of hypoxia inducible factor-1alpha siRNA on theinvasion of human Hela cells and expression of relatedproteins显示文摘The effects of hypoxia on the invasion and the related protein expression of Hela cells and the role of hypoxia inducible factor-1α(HIF-1α)were investigated.The Hela cells were divided into three groups,namely,H0(non-transfected Hela cells),H1(pGenesil-1 empty plasmid-transfected Hela cells),and H2(HIF-1α-shRNA plasmid-transfected Hela cells),and were cultured under hypoxia(1%O2)and normoxia for 48 h.The expression of HIF-1α,E-cadherin,β-catenin,and actin was detected using Western blot.The scratch test and the invasion assay were applied to examine the invasion in each group.The expression of HIF-1α,E-cadherin,andβ-catenin in tumor grafts was assayed immunohistochemically.Western blot results revealed that the bands of HIF-1α,E-cadherin,β-catenin,and actin proteins were detected in the H0 and H1 groups under hypoxia for 48 h.The expression of E-cadherin,β-catenin,and actin was detected in the H2 group under hypoxia for 48 h,and normoxia.In the H0,H1,and H2 groups under normoxia,and the H2 group under hypoxia for 48 h,no expression of HIF-1αwas detectable.The scratch test showed that the invasive ability in the H2 group was significantly alleviated.Immunohistochemi-cally,it was found that there was a significant difference in the expression of HIF-1α,E-cadherin,andβ-catenin between the H1 and H2 groups(P<0.05),but the difference was not significant between the H0 and H1 groups.It was concluded that the effects of hypoxia on the invasion of human cervical cancer Hela cells and the expression of related proteins(E-cadherin,β-catenin,and actin)depend on HIF-1α. | Bin YANG Xianglin YUAN Yanmei ZOU Qingsong XI Guoxian LONG Qiang FU Guangyuan HU | 2009 | Frontiers of Medicine2009，3，3： | 0 |
| 12 | Research progress on lung cancer stem cells in epidermal growth factor receptor–tyrosine kinase inhibitor targeted therapy resistance in lung adenocarcinoma显示文摘Lung cancer is the leading cause of cancer-related deaths globally.In recent years,with the widespread use of genetic testing,epidermal growth factor receptor–tyrosine kinase inhibitor(EGFR-TKI)–targeted drugs have been efficacious to patients with lung adenocarcinoma exhibiting EGFR mutations.However,resistance to treatment is inevitable and eventually leads to tumor progression,recurrence,and reduction in the overall treatment efficacy.Lung cancer stem cells play a crucial role in the development of resistance toward EGFR-TKI–targeted therapy for lung adenocarcinoma.Lung cancer stem cells possess self-renewal,multilineage differentiation,and unlimited proliferation capabilities,which efficiently contribute to tumor formation and ultimately lead to tumor recurrence andmetastasis.In this study,we evaluated the origin,markers,stemness index,relevant classic studies,resistance mechanisms,related signaling pathways,and strategies for reversing lung cancer stem cell resistance to EGFR-TKIs to provide new insights on delaying or reducing resistance and to improve the treatment efficacy of patients with EGFR-mutated lung adenocarcinoma in the future. | Hong Zhang Yanbin Wang Xianglin Yuan Yanmei Zou Hua Xiong | 2024 | Oncology and Translational Medicine2024，10，1： | 0 |
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