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| 1 | Incidence and mortality of stomach cancer in China,2014显示文摘Objective: In this study,we aimed to estimate the updated incidence and mortality rate of stomach cancer based on the cancer registration data in 2014,collected by the National Central Cancer Registry of China(NCCRC).Methods: In 2017,339 registries' data were qualified based on the criteria of data quality control of the NCCRC.Cases of stomach cancer were retrieved from the national database.We estimated numbers of stomach cancer cases and deaths in China using age-specific rates and corresponding national population stratified by area,sex,agegroup(0,1–4,5–9,10–14,…,85+).Chinese standard population in 2000 and Segi's world population were applied for age-standardized incidence and mortality rates.Results: In 2014,410,400 new stomach cancer cases and 293,800 cancer-associated deaths were estimated to have occurred in China.The crude incidence rate of stomach cancer was 30.00/100,000,age-standardized incidence rates by Chinese standard population(ASIRC) and by world standard population(ASIRW) were 19.62/100,000 and19.51/100,000,respectively.The crude mortality rate of stomach cancer was 21.48/100,000,age-standardized mortality rates by Chinese(ASMRC) and by world standard population(ASMRW) were 13.44/100,000 and13.30/100,000,respectively.Incidence and mortality rates in rural areas were both higher than that in urban areas.Stomach cancer has a strong relationship with gender and age.The disease has occurred more frequently among men than women with a male to female ratio of 2.4 for ASIRC.After age group of 40-44 years,incidence rates are substantially higher in men than in women,same pattern was seen for age-specific mortality rates.Conclusions: There is still a heavy burden of stomach cancer in China.The incidence and mortality patterns of stomach cancer show substantial gender and regional disparities.Great effort is needed to provide more accessible health services,sufficient financial resources,and adequate cancer-care infrastructure for the Chinese population,especially for people living in rural areas. | Lei Yang Rongshou Zheng Ning Wang Yannan Yuan Shuo Liu Huichao Li Siwei Zhang Hongmei Zeng Wanqing Chen | 2018 | Chinese Journal of Cancer Research2018，30，3： | 114 |
| 2 | Transplantation of UC-MSCs on collagen scaffold activates follicles in dormant ovaries of POF patients with long history of infertility显示文摘Premature ovarian failure(POF) is a refractory disease for clinical treatment with the goal of restoring fertility. In this study,umbilical cord mesenchymal stem cells on a collagen scaffold(collagen/UC-MSCs) can activate primordial follicles in vitro via phosphorylation of FOXO3 a and FOXO1. Transplantation of collagen/UC-MSCs to the ovaries of POF patients rescued overall ovarian function, evidenced by elevated estradiol concentrations, improved follicular development, and increased number of antral follicles. Successful clinical pregnancy was achieved in women with POF after transplantation of collagen/UC-MSCs or UC-MSCs. In summary, collagen/UC-MSC transplantation may provide an effective treatment for POF. | Lijun Ding Guijun Yan Bin Wang Lu Xu Yan Gu Tong Ru Xiaoying Cui Lei Lei Jingyu Liu Xiaoqiang Sheng Bin Wang Chunxue Zhang Yanjun Yang Ruiwei Jiang Jianjun Zhou Na Kong Feifei Lu Huaijun Zhou Yannan Zhao Bing Chen Yali Hu Jianwu Dai Haixiang Sun | 2018 | Science China(Life Sciences)2018，61，12： | 43 |
| 3 | On Reliability-optimized Controller Placement for Software-Defined Networks显示文摘By decoupling control plane and data plane,Software-Defined Networking(SDN) approach simplifies network management and speeds up network innovations.These benefits have led not only to prototypes,but also real SDN deployments.For wide-area SDN deployments,multiple controllers are often required,and the placement of these controllers becomes a particularly important task in the SDN context.This paper studies the problem of placing controllers in SDNs,so as to maximize the reliability of SDN control networks.We present a novel metric,called expected percentage of control path loss,to characterize the reliability of SDN control networks.We formulate the reliability-aware control placement problem,prove its NP-hardness,and examine several placement algorithms that can solve this problem.Through extensive simulations using real topologies,we show how the number of controllers and their placement influence the reliability of SDN control networks.Besides,we also found that,through strategic controller placement,the reliability of SDN control networks can be significantly improved without introducing unacceptable switch-to-controller latencies. | HU Yannan WANG Wendong GONG Xiangyang QUE Xirong CHENG Shiduan | 2014 | China Communications2014，11，2： | 25 |
| 4 | Malate transported from chloroplast to mitochondrion triggers production of ROS and PCD in Arabidopsis thaliana显示文摘规划房间死亡(PCD ) 是一个基本生物过程。在马赛克死亡 1 的缺乏(MOD1 ) ,质体局部性的 enoyl-ACP reductase,导致反应的氧种类(ROS ) 和 PCD 的累积,它能被 mitochondrial 建筑群压制我变化,从叶绿体显示一个信号到线粒体。然而,这个信号尚待被阐明。在这研究,通过克隆并且分析一系列 mod1 suppressors,我们揭示调整 mitochondrial ROS 和扳机 PCD 的产生的一条全面细胞器通讯小径。我们证明在 PLASTIDIAL NAD 依赖的 MALATE 脱氢酶(plNAD-MDH ) 的变化, chloroplastic DICARBOXYLATE TRANSPORTER 1 (DiT1 ) 并且(mMDH1 ) MITOCHONDRIAL MALATE 脱氢酶 1 能各在 mod1 救 ROS 累积和 PCD 显型,经由 malate 梭从叶绿体表明直接通讯到线粒体。进一步的研究证明这些元素在不同光周期条件下面在氧化还原作用动态平衡和植物生长起关键作用。而且,我们表明 ROS 水平和 PCD 显著地在房间,它能是戏剧性地稀释了由的对待 malate 的 HeLa 被增加人的基因 MDH2 击倒, Arabidopsis mMDH1 的 ortholog。这些结果揭开在植物和动物系统的一条保存导致 malate 的 PCD 小径,革命化我们在细胞器之间的通讯的理解。 | Yannan Zhao Lilan Luo Jiesi Xu Peiyong Xin Hongyan Guo Jian Wu Lin Bai Guodong Wang Jinfang Chu Jianru Zuo Hong Yu Xun Huang Jiayang Li | 2018 | Cell Research2018，28，4： | 24 |
| 5 | One-year clinical study of NeuroR egen scaffold implantation following scar resection in complete chronic spinal cord injury patients显示文摘The objective of this clinical study was to assess the safety and feasibility of the collagen scaffold, Neuro Regen scaffold, one year after scar tissue resection and implantation. Scar tissue is a physical and chemical barrier that prevents neural regeneration. However, identification of scar tissue is still a major challenge. In this study, the nerve electrophysiology method was used to distinguish scar tissue from normal neural tissue, and then different lengths of scars ranging from 0.5–4.5 cm were surgically resected in five complete chronic spinal cord injury(SCI) patients. The NeuroR egen scaffold along with autologous bone marrow mononuclear cells(BMMCs), which have been proven to promote neural regeneration and SCI recovery in animal models, were transplanted into the gap in the spinal cord following scar tissue resection. No obvious adverse effects related to scar resection or Neuro Regen scaffold transplantation were observed immediately after surgery or at the 12-month follow-up. In addition, patients showed partially autonomic nervous function improvement, and the recovery of somatosensory evoked potentials(SSEP) from the lower limbs was also detected. The results indicate that scar resection and Neuro Regen scaffold transplantation could be a promising clinical approach to treating SCI. | Zhifeng Xiao Fengwu Tang Jiaguang Tang Huilin Yang Yannan Zhao Bing Chen Sufang Han Nuo Wang Xing Li Shixiang Cheng Guang Han Changyu Zhao Xiaoxiong Yang Yumei Chen Qin Shi Shuxun Hou Sai Zhang Jianwu Dai | 2016 | Science China(Life Sciences)2016，59，7： | 18 |
| 6 | Deficient plastidic fatty acid synthesis triggers cell death by modulating mitochondrial reactive oxygen species显示文摘 | Jian Wu Yuefeng Sun Yannan Zhao Jian Zhang Lilan Luo Meng Li Jinlong Wang Hong Yu Guifu Liu Liusha Yang Guosheng Xiong Jian-Min Zhou Jianru Zuo Yonghong Wang Jiayang Li | 2015 | Cell Research2015，25，5： | 13 |
| 7 | Population-based cancer incidence analysis in Beijing, 2008-2012显示文摘Objective: To analyze the incidence of cancer during 2008-2012 in Beijing, China, and compare the cancer spectrum with that during 1998-1999.Methods: Data from the Beijing Cancer Registry(BCR), which covered 12 million residents and 16 administrative regions in Beijing, were checked and evaluated on basis of the criteria of data quality from the National Central Cancer Registry(NCCR) of China. Incidences were calculated stratified by cancer type, sex, areas(urban/rural), and age. The Chinese census population in 1982 and the world Segi's population were used for calculating the age-standardized incidences.Results: A total of 177,101 new cancer cases were diagnosed in Beijing between 2008 and 2012. The crude incidence rate(CR) of all cancers was 282.64/100,000(290.71/100,000 in males and 274.45/100,000 in females). The age-standardized rates by Chinese standard population(ASR-China) and by world standard population(ASR-world) were 124.46/100,000 and 161.18/100,000, respectively. Female breast cancer was the most common cancer, followed by lung cancer, colorectal cancer, liver cancer, and stomach cancer, with the CR of 59.87/100,000, 59.21/100,000, 32.49/100,000, 19.81/100,000 and 17.96/100,000, respectively. In urban areas, female breast cancer(68.50/100,000) was still the most common cancer, followed by lung cancer(61.23/100,000), colorectal cancer(37.23/100,000), prostate cancer(20.49/100,000) and stomach cancer(20.07/100,000). In rural areas, lung cancer(55.94/100,000) was the most common cancer, followed by female breast cancer(45.87/100,000), colorectal cancer(24.77/100,000), liver cancer(20.68/100,000) and stomach cancer(14.52/100,000). Great changes of the cancer spectrum were found from the period of 1998-1999 to the period of 2011-2012 in Beijing.Conclusions: The cancer burden in Beijing was heavier than the national average level. Cancer prevention and control strategies, especially for lung, colorectal, prostate and female thyroid cancers, should be enhanced. | Lei Yang Yannan Yuan Tingting Sun Huichao Li Ning Wang | 2015 | Chinese Journal of Cancer Research2015，27，1： | 12 |
| 8 | Energy harvesting via nonlinear energy sink for whole-spacecraft显示文摘This paper presents nonlinear energy sink with giant magnetostrictive-piezoelectric material for energy harvesting of the wholespacecraft vibration reduction system. The whole-spacecraft vibration attenuation system can effectively reduce vibration and achieve self-tuning enhanced energy harvesting range. The open-circuit voltage generated at low frequency is affected by the magnetic field force, alternating magnetic field and relative displacement. In order to acquire a steady periodic solution of the energy harvesting system, a combination of the harmonic balance method and pseudo arc length continuation technique is used.The numerical outcomes are consistent with the analytical outcomes in a certain range, which also proves the accuracy and reliability of the results. The amplitude and voltage of the energy harvesting system are analyzed by parameters such as cubic stiffness, viscous damping, and external excitation acceleration. In addition, this paper provides a new idea for broadband energy harvesting. | ZHANG YeWei LU YanNan CHEN LiQun | 2019 | Science China(Technological Sciences)2019，62，9： | 12 |
| 9 | Late Mesozoic-Cenozoic Exhumation of the Northern Hexi Corridor:Constrained by Apatite Fission Track Ages of the Longshoushan显示文摘The apatite fission track(AFT) ages and thermal modeling of the Longshoushan and deformation along the northern Hexi Corridor on the northern side of the Qinghai-Tibetan Plateau show that the Longshoushan along the northern corridor had experienced important multi-stage exhumations during the Late Mesozoic and Cenozoic. The AFT ages of 7 samples range from 31.9 Ma to 111.8 Ma.Thermal modeling of the AFT ages of the samples shows that the Longshoushan experienced significant exhumation during the Late Cretaceous to the Early Cenozoic(-130-25 Ma). The Late Cretaceous exhumation of the Longshoushan may have resulted from the continuous compression between the Lhasa and Qiangtang blocks and the flat slab subduction of the Neo-Tethys oceanic plate, which affected wide regions across the Qinghai-Tibetan Plateau. During the Early Cenozoic, the Longshoushan still experienced exhumation, but this process was caused by the Indian-Eurasian collision. Since this time,the Longshoushan was in a stable stage for approximately 20 Ma and experienced erosion. Since ~5 Ma,obvious tectonic deformation occurred along the entire northern Hexi Corridor, which has also been reported from the peripheral regions of the Qinghai-Tibetan Plateau, especially in the Qilianshan and northeastern margin of the plateau. The AFT ages and the Late Cenozoic deformation of the northern Hexi Corridor all indicate that the present northern boundary of the Qinghai-Tibetan Plateau is situated along the northern Hexi Corridor. | ZHANG Beihang ZHANG Jin WANG Yannan ZHAO Heng LI Yanfeng | 2017 | Acta Geologica Sinica(English Edition)2017，91，5： | 11 |
| 10 | Cancer incidence in Beijing, 2014显示文摘Objective: To analyze cancer incidence data in Beijing in 2014 and temporal trends for selected common cancers during 2005 and 2014.Methods: A total of 144 secondary and tertiary hospitals reported newly diagnosed cancer cases to Beijing Cancer Registry, which covers 13 million residents in Beijing. The cancer incidence rate was calculated in strata by cancer type, sex, age group and area. The population composition of China in 1982 and Segi's population structure were used to calculate age-standardized rates. Extensive procedures were used to assure the quality of the data.Results: The overall data quality indicators of the percentage of morphology verification(MV)(%), the percentage of death certificate-only(DCO)(%) and the mortality to incidence ratio(M/I) were 72.15%, 0.94% and0.54 respectively. A total of 45,300 new cancer cases were diagnosed in Beijing in 2014. The incidence rate was341.92/100,000(343.50/100,000 in males, 340.33/100,000 in females), and the age-standardized incidence rates by Chinese standard population(ASIRC) and by world standard population(ASIRW) were 143.48/100,000 and182.99/100,000, respectively. The cumulative incidence rate for cancer before 75 years was 20.61%. Cancers of lung, colorectum, liver, stomach and prostate were the top five common cancer types for males, while cancers of breast, lung, thyroid, colorectum and uterus were the top five common cancer types for females. The different patterns were also observed between rural and urban areas. Regarding temporal trends, the incidence of thyroid cancer has the fastest growth between 2005 and 2014. The incidence of liver cancer decreased, and stomach and esophageal cancer also decreased significantly for males in the last decade. Incidence rate for lung cancer was relatively stable during that period of time.Conclusions: With more than 45,000 new cases in Beijing in 2014, cancer remains an important public health problem. Actions should be taken to diminish total cancer incidence in Beijing. | Shuo Liu Lei Yang Yannan Yuan Huichao Li Jing Tian Sijia Lu Ning Wang Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，1： | 11 |
| 11 | Process optimization of neodymium chloride solutions precipitated by magnesium bicarbonate显示文摘Rare earths(REs) are of vital importance for the development of new materials and green energy.Magnesium bicarbonate is one of the most recyclable and environmental-friendly precipitant for REs recovery from leaching solutions. Nd_2(CO_3)_3 has difficulties in industrial production. So in this study,the precipitation of neodymium from chloride solution by magnesium bicarbonate are investigated. The effects of feeding method, [HCO_3^-]/[Nd^(3+)] mole ratio, feeding speed and reaction temperature on yield and impurity(magnesia) content are systematically studied. Results show that the impurity(magnesia)content decreases to 0.010 wt% with a yield approaching to 100% obtained under the conditions of[HCO_3^-]/[Nd^(3+)] = 3.00 by parallel flow addition at 50 ℃. The major impurity(magnesia) in rare earth carbonates mainly presents in the form of physical absorption, which can be easily removed by scrubbing. Therefore, it offers a promising green process that uses magnesium bicarbonate to produce neodymium carbonate due to its cycling of carbon dioxide, magnesium salt and waste water. | Yannan Yan Yang Xu Xiaowei Huang Zongyu Feng Yongke Hou Kai Li Liangshi Wang Yihanna Hu | 2019 | Journal of Rare Earths2019，37，4： | 10 |
| 12 | Ce-doped LiNi_(1/3)Co_((1/3-x/3))Mn_(1/3)Ce_(x/3)O_2 cathode materials for use in lithium ion batteries显示文摘LiNi1/3Co1/3Mn1/3O2 and Ce-doped LiNi1/3Co1/3Mn1/3O2 cathode materials were synthesized by a co-precipitation method and solid phase synthesis and characterized using X-ray diffraction(XRD) and scanning electron microscopy(SEM).The results indicated that the resultant cathode materials with different Ce content all had a good layer structure and high crystallinity.Electrochemical performance testing of the cathode materials showed that the discharge capacity increased with increasing Ce content while the initial reversible capacity attenuation decreased with Ce doping.When the Ce content of the cathode materials is x=0.2,and the current charge and discharge rate is a constant 0.2 C,the discharge capacity maintained 91% of its initial capacity after cycling 50 times. | ZHANG YingJie XIA ShuBiao ZHANG YanNan DONG Peng YAN Yuxing YANG RuiMing | 2012 | Chinese Science Bulletin2012，57，32： | 8 |
| 13 | Inhibition of miR-144-3p exacerbates non-small cell lung cancer progression by targeting CEP55显示文摘Increasing evidence has indicated that microRNA dysregulation is closely related to the occurrence and development of cancers.Herein,we investigated the relationship between miR-144-3p&CEP55 expression.We then evaluated the association between miR-144-3p&CEP55 expression,&proliferation,invasion&apoptosis of non-small cell lung cancer[NSCLC]cells.Real-time quantitative PCR results revealed that CEP55 was over-expressed whereas miR-144-3p was underexpressed in NSCLC tissues.CCK-8 assay,wound healing assay,&flow cytometry further revealed that overexpression of miR-144-3p significantly inhibited proliferation&migration,but promoted apoptosis of A549 cells.Conversely,inhibition of miR-144-3p promoted proliferation. | Ming Li Yannan Liu Xinglin Jiang Yuanxin Hang Haiying Wang Hang Liu Zhuo Chen Yubo Xiao | 2021 | Acta Biochimica et Biophysica Sinica2021，53，10： | 7 |
| 14 | A curve flow evolved by a fourth order parabolic equation显示文摘We study a fourth order curve flow, which is the gradient flow of a functional describing the shapes of human red blood cells. We prove that for any smooth closed initial curve in R2, the flow has a smooth solution for all time and the solution subconverges to a critical point of the functional. | LIU YanNan JIAN HuaiYu | 2009 | Science China Mathematics2009，52，10： | 6 |
| 15 | Massive cranium from Harbin in northeastern China establishes a new Middle Pleistocene human lineage显示文摘It has recently become clear that several human lineages coexisted with Homo sapiens during the late Middle and Late Pleistocene.Here,we report an archaic human fossil that throws new light on debates concerning the diversification of the Homo genus and the origin of H.sapiens.The fossil was recovered in Harbin city in northeastern China,with a minimum uranium-series age of 146 ka.This cranium is one of the best preserved Middle Pleistocene human fossils.Its massive size,with a large cranial capacity(1,420 mL)falling in the range of modern humans,is combined with a mosaic of primitive and derived characters.It differs from all the other named Homo species by presenting a combination of features,such as long and low cranial vault,a wide and low face,large and almost square orbits,gently curved but massively developed supraorbital torus,flat and low cheekbones with a shallow canine fossa,and a shallow palate with thick alveolar bone supporting very large molars.The excellent preservation of the Harbin cranium advances our understanding of several less-complete late Middle Pleistocene fossils from China,which have been interpreted as local evolutionary intermediates between the earlier species Homo erectus and later H.sapiens.Phylogenetic analyses based on parsimony criteria and Bayesian tip-dating suggest that the Harbin cranium and some other Middle Pleistocene human fossils from China,such as those from Dali and Xiahe,form a third East Asian lineage,which is a part of the sister group of the H.sapiens lineage.Our analyses of such morphologically distinctive archaic human lineages from Asia,Europe,and Africa suggest that the diversification of the Homo genus may have had a much deeper timescale than previously presumed.Sympatric isolation of small populations combined with stochastic long-distance dispersals is the best fitting biogeographical model for interpreting the evolution of the Homo genus. | Xijun Ni Qiang Ji Wensheng Wu Qingfeng Shao Yannan Ji Chi Zhang Lei Liang Junyi Ge Zhen Guo Jinhua Li Qiang Li Rainer Grun Chris Stringer | 2021 | The Innovation2021，2，3： | 6 |
| 16 | Secular trends in incidence of lung cancer by histological type in Beijing, China, 2000-2016显示文摘Objective: The objective of this study was to characterize secular trends in the sex-specific, age-standardized incidence of lung cancer by histological type in Beijing, China, from 2000 to 2016 based on data from a populationbased cancer registry.Methods: Data on the incidence of cancer from 2000 to 2016 were obtained from the Beijing Cancer Registry.We examined trends in the sex-specific, age-standardized incidence of lung cancer by histological type using a Joinpoint regression model.Results: A total of 117,409 cases of lung cancer were diagnosed from 2000 to 2016. Overall, 73,062(62.23%)patients were males. The most common histological type among both sexes was adenocarcinoma; however, the proportion of adenocarcinoma differed significantly between males and females(45.36% vs. 77.14%, respectively,P<0.0001). The age-standardized incidence of total lung cancer increased from 2000 to 2010 with an annual percent change(APC) of 2.2% [95% confidence interval(95% CI), 1.5% to 2.9%] and stabilized thereafter. Among males, the incidence of total lung cancer peaked in 2008 and then decreased slightly, with an APC of-1.1%(95%CI,-2.1% to-0.1%). Among females, the incidence increased continuously during the study period, with an APC of 1.4%(95% CI, 0.9% to 1.9%). The incidence of squamous cell carcinoma decreased significantly in recent years among both sexes, with APCs of-2.6%(95% CI,-4.5% to-0.6%) from 2007 to 2016 for males and-5.4%(95%CI,-7.2% to-3.6%) from 2004 to 2016 for females. In contrast, the incidence of adenocarcinoma increased continuously throughout the study period, by APCs of 4.0%(95% CI, 2.6% to 5.4%) for males and 6.2%(95% CI,4.8% to 7.6%) for females. The incidence of small cell carcinoma peaked in 2007 and stabilized thereafter among males, whereas it peaked in 2012 and then decreased with an APC of-14.7%(95% CI,-25.3% to-2.6%) among females. The incidence of large cell carcinoma and other specified malignant neoplasm did not change much,whereas the incidence of unspecified type decreased among both sexes during the study period.Conclusions: Although the incidence of squamous cell carcinoma decreased significantly among both sexes in recent years in Beijing, China, adenocarcinoma increased continuously throughout the study period among both sexes. Knowledge of differences in trends is useful for surveillance and control of lung cancer. However, the reason for the increase in adenocarcinoma remains unclear and warrants investigation. | Lei Yang Ning Wang Yannan Yuan Shuo Liu Huichao Li Jing Tian Jiafu Ji Aiguo Ren | 2019 | Chinese Journal of Cancer Research2019，31，2： | 6 |
| 17 | The Three-Dimensional Collagen Scaffold Improves the Sternness of Rat Bone Marrow Mesenchymal Stem Cells显示文摘因为他们的自强和 multipotential 能力,间充质的干细胞(MSC ) 为许多疾病的治疗显示出大诺言。MSC 通常是有教养的在上二维(2D ) 在 vitro 的底层。有指示,他们可以同时失去他们是的 stemness 和 multipotentiality 延长 2D 的结果文化。在这研究,我们使用了三维(3D ) 是的骨胶原脚手架老鼠 MSC 搬运人并且在 3D 骨胶原脚手架上把 MSC 的性质与单层作比较有教养的 MSC。结果证明骨胶原脚手架对老鼠 MSC 坚持和增长合适。与在 2D 文化下面的 MSC 相比,更重要地, 3D MSC 显著地维持了 stemness 基因(Oct4, Sox2, Rex-1 和 Nanog ) 的更高的表示层次,产出形成殖民地的 units-fibroblastic (CFU-F ) 的高频率并且显示出在正式就职之上的提高的 osteogenic 和 adipogenic 区别效率。因此, 3D 骨胶原脚手架可能为当在 vitro 维持干细胞性质时,扩展老鼠 MSC 是有益的。 | Sufang Han Yannan Zhao Zhifeng Xiao Jin Han Bing Chen Lei Chen Jianwu Dai | 2012 | Journal of Genetics and Genomics2012，39，12： | 6 |
| 18 | The relationship between energy consumption and economic growth and the development strategy of a low-carbon economy in Kazakhstan显示文摘Fossil energy is the material basis of human survival, economic development and social progress. The relationship between energy consumption and economic growth is becoming increasingly close. However, energy consumption is the major source of greenhouse gases, which can significantly affect the balance of the global ecosystem. It has become the common goal of countries worldwide to address climate change, reduce carbon dioxide emissions, and implement sustainable development strategies. In this study, we applied an approximate relationship analysis, a decoupling relationship analysis, and a trend analysis to explore the relationship between energy consumption and economic growth using data from Kazakhstan for the period of 1993–2010. The results demonstrated:(1) the total energy consumption and GDP in Kazakhstan showed a 'U'-type curve from 1993 to 2010. This curve was observed because 1993–1999 was a period during which Kazakhstan transitioned from a republic to an independent country and experienced a difficult transition from a planned to a market economy. Then, the economic system became more stable and the industrial production increased rapidly because of the effective financial, monetary and industrial policy support from 2000 to 2010.(2) The relationships between energy consumption and carbon emissions, economic growth and energy exports were linked; the carbon emissions were mainly derived from energy consumption, and the dependence of economic growth on energy exports gradually increased from 1993 to 2010. Before 2000, the relationship between energy consumption and economic growth was in a recessional decoupling state because of the economic recession. After 2000, this relationship was in strong and weak decoupling states because the international crude oil prices rose and energy exports increased greatly year by year.(3) It is forecasted that Kazakhstan cannot achieve its goal of energy consumption by 2020. Therefore, a low-carbon economy is the best strategic choice to address climate change from a global perspective in Kazakhstan. Thus, we proposed strategies including the improvement of the energy consumption structure, the development of new energy and renewable energy, the use of cleaner production technologies, the adjustment and optimization of the industrial structure, and the expansion of forest areas. | XIONG Chuanhe YANG Degang HUO Jinwei ZHAO Yannan | 2015 | Journal of Arid Land2015，7，5： | 6 |
| 19 | Regulation of mitochondrial NAD pool via NAD^+ transporter 2 is essential for matrix NADH homeostasis and ROS production in Arabidopsis显示文摘Reactive oxygen species(ROS) play a crucial role in numerous biological processes in plants, including development, responses to environmental stimuli, and programmed cell death(PCD). Deficiency in MOSAIC DEATH 1(MOD1), a plastid-localized enoyl-ACP reductase essential for de novo fatty acid biosynthesis in Arabidopsis thaliana, leads to the increased malate export from chloroplasts to mitochondria, and the subsequent accumulation of mitochondria-generated ROS and PCD. In this study, we report the identification and characterization of a mod1 suppressor, som592. SOM592 encodes mitochondrion-localized NAD^+ transporter 2(NDT2). We show that the mitochondrial NAD pool is elevated in the mod1 mutant. The som592 mutation fully suppressed mitochondrial NADH hyper-accumulation, ROS production, and PCD in the mod1 mutant, indicating a causal relationship between mitochondrial NAD accumulation and ROS/PCD phenotypes. We also show that in wild-type plants, the mitochondrial NAD+uptake is involved in the regulation of ROS production in response to continuous photoperiod. Elevation of the alternative respiration pathway can suppress ROS accumulation and PCD in mod1, but leads to growth restriction. These findings uncover a regulatory mechanism for mitochondrial ROS production via NADH homeostasis in Arabidopsis thaliana that is likely important for growth regulation in response to altered photoperiod. | Lilan Luo Yajun He Yannan Zhao Qian Xu Jian Wu Haiyan Ma Hongyan Guo Lin Bai Jianru Zuo Jian-Min Zhou Hong Yu Jiayang Li | 2019 | Science China(Life Sciences)2019，62，8： | 5 |
| 20 | Systematics,Behavior and Living Environment of Shantungosaurus Giganteus(Dinosauria:Hadrosauridae)显示文摘根据 taphonomy,骨学的解剖和个体发生的变化, Zhuchengosaurus 敲奏编钟的一种技巧赵等, 2007 被认为是与 Shantungosaurus giganteus 胡,一起的 synonymic 1973 此处。这份报纸也处理 S 的生活行为。giganteus 和环境在哪个 S。giganteus 生活了。S。giganteus 被认为是一条陆上、群居的食草的恐龙并且与丰富的雨和繁荣的植被在温暖的天气在山和丘陵间的低地住在一起。 | JI Yannan WANG Xuri LIU Yongqing JI Qiang | 2011 | Acta Geologica Sinica(English Edition)2011，85，1： | 5 |
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