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| 1 | ^(40)Ar-^(39)Ar dating and geological implication of auriferous altered rocks from the middle-deep section of Q875 gold-quartz vein in Xiaoqinling area, Henan,China显示文摘The 40Ar-39Ar age method is employed in this work to analyze the auriferous altered rocks from the middle-deep section of the Q875 gold-quartz vein in the Xiao-qinling area, and the results show that the main gold deposition of the Q875 occurred in ca. 128-126 Ma. As a typical gold-bearing quartz vein in this gold-rich area, the age data obtained from the Q875 also constrain on the metallogenic time of the lode gold deposits developed in the same geological settings. This geochronological study supplies new evidence for further understanding the timing of gold mineralization, the genesis of gold deposits and the geodynamic settings in Xiaoqinling area. | WANG Yitian, MAO Jingwen, LU Xinxiang & YE AnwangInstitute of Mineral Resources, Chinese Academy of Geological Sciences, Beijing 100037, China Institute of Geological Sciences, Henan Province, Zhengzhou 450053, China Lingbao Bureau of Geology and Mineral | 2002 | Chinese Science Bulletin2002，47，20： | 36 |
| 2 | Effect of electroacpuncture of Neiguan(PC 6)and Tianquan(PC 2)on skin temperature,blood perfusion,and adrenoceptor response in rats with acute myocardial ischemia显示文摘OBJECTIVE: To investigate the effect of electroacupuncture(EA) of acupoints Neiguan(PC 6) and Tianquan(PC 2) on the skin temperature, blood perfusion, and alpha1-and beta2-adrenoreceptor(α1-AR and β2-AR) protein and m RNA level in rats with acute myocardial ischemia.METHODS: Thirty male adult Wistar rats [(230 ±20) g] were randomly assigned into five groups(n = 6 each): a control group, sham operation group, model group, model group treated with EA at low frequency(L-EA, 2 Hz, 1 m A) and model group treated with EA at high frequency(H-EA, 100 Hz, 1 m A). The rat model was prepared by ligating the left anterior descending coronary artery. Electroacupuncture was performed at the left Neiguan(PC 6) for 20 min daily for 3 d. After the 3 rd time of the treatment, measurements of skin blood perfusion and temperature in Neiguan(PC 6) and Tianquan(PC 2) in all groups were made by laser speckle contrast imaging and infrared thermal image instrument. Real-time PCR and ELISA were used to measure m RNA level and protein level of α1-AR andβ2-AR in the skin tissues of Neiguan(PC 6) and Tianquan(PC 2), respectively. Serum levels of c Tn T and electrocardiogram were used to identify the state of myocardium.RESULTS: In the group receiving electroacupunture at Neiguan(PC 6), compared with control group,the skin temperature, blood perfusion, and β2-AR m RNA and protein level of model group significantly decreased(P < 0.05), α1-AR m RNA and protein level of model group significantly increased(P < 0.05);compared with model group, the skin temperature,blood perfusion, and β2-AR m RNA and protein level of L-EA significantly increased(P < 0.05), α1-AR m RNA and protein level of L-EA and H-EA significantly decreased(P < 0.05). The same trend has taken place in the former four groups of the Tianquan(PC 2).CONCLUSION: Low-or high-frequency electroacupuncture can improve the skin temperature and blood perfusion which may be induced by decreasingthelevelofα1-ARandincreasingthelevelofβ2-AR of the Neiguan(PC 6) and Tianquan(PC 2) in the rat with acute myocaidial ischemia. | Wang Dan Ji Bo Zhao Guozhen Yan Mingna Bai Hongxin Sun Xiaomin Dai Jian Lu Yawen Liu Yitian You Min Wu Jiaojuan Ge Yunpeng Su Hang Cheng Kai | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 3 |
| 3 | Graphene oxide coated three-dimensional printed biphasic calcium phosphate scaffold for angiogenic and osteogenic synergy in repairing critical-size bone defect显示文摘The custom-tailored medicine requires a developmental strategy that integrates excellent osteogene-sis with mechanical stability to enhance the reconstruction of the critical-size bone defect(CSBD)and the healing process in weight-bearing bone.We prepared three-dimensional(3D)printed biphasic cal-cium phosphate(BCP)scaffolds composited with nano-graphene oxide(GO).The biological effects of the GO/BCP composite scaffolds could induce the differentiation of rat bone marrow stem cells(BM-SCs)and the migration of human umbilical vein endothelial cells(HUVECs)for bone repair.The proper ratio of GO in the composite scaffold regulated the composites’surface roughness and hydrophilicity to a suitable range for the adhesion and proliferation of BMSCs and HUVECs.Besides,the GO/BCP composite scaffold increased osteogenesis and angiogenesis by activating BMP-2,RUNX-2,Smad1/4,and VEGF.The customized intramedullary nail combined with GO/BCP scaffold was applied to repair CSBD(2.0 cm in length)in a beagle femur model.This fixation strategy was confirmed by finite element analysis.In vivo,the results indicated that the custom-made internal fixation provided sufficient stability in the early stage,ensuring bone healing in a considerable mechanical environment.At 9 months postoperatively,longitudi-nal bony union and blood vessels in osteon were observed in the CSBD area with partial degradation in the 0.3%GO/BCP group.In the three-point bending test,the ultimate load of 0.3%GO/BCP group reached over 50%of the normal femur at 9 months after repair.These results showed a promising application of osteogenic GO/BCP scaffold and custom-made intramedullary nails in repairing CSBD of the beagle femur.This effective strategy could provide an option to treat the clinical CSBD in weight-bearing bones. | Yitian Wang Yonghao Wu Yuqi Zhang Xiangfeng Li Li Min Quanle Cao Yi Luo Xiao Yang Minxun Lu Yong Zhou Xiangdong Zhu Chongqi Tu Xingdong Zhang | 2023 | Journal of Materials Science & Technology2023，，14： | 1 |
| 4 | Simulation-Guided Design of Bamboo Leaf-Derived Carbon-Based High-Efficiency Evaporator for Solar-Driven Interface Water Evaporation显示文摘Solar interface water evaporation has been demonstrated to be an advanced method for freshwater production with high solar energy utilization.The development of evaporators with lower cost and higher efficiency is a key challenge in the manufacture of practical solar interface water evaporation devices.Herein,a bamboo leaf-derived carbon-based evaporator is designed based on the light trace simulation.And then,it is manufactured by vertical arrangement and carbonization of bamboo leaves and subsequent polyacrylamide modification.The vertically arranged carbon structure can extend the light path and increase the light-absorbing area,thus achieving excellent light absorption.Furthermore,the continuous distribution of polyacrylamide hydrogel between these vertical carbons can support high-speed water delivery and shorten the evaporation path.Therefore,this evaporator exhibits an ultrahigh average light absorption rate of~96.1%,a good water evaporation rate of 1.75 kg m^(-2) h^(-1),and an excellent solar-to-vapor efficiency of 91.9%under one sun irradiation.Furthermore,the device based on this evaporator can effectively achieve seawater desalination,heavy metal ion removal,and dye separation while completing water evaporation.And this device is highly available for actual outdoor applications and repeated recycling. | Yitian Wu Rui Kong Chaoliang Ma Lanze Li Yu Zheng Yingzhuo Lu Lulu Liang Yajun Pang Qiang Wu Zhehong Shen Hao Chen | 2022 | Energy & Environmental Materials2022，5，4： | 1 |
| 5 | Adaptive Coupled Synchronization Among Multi-Lorenz Systems Family 显示文摘 | LU Jun'an HAN Xiuping LI Yitian | 2007 | Chaos Solitons and Fractals2007，31，4： | 1 |
| 6 | Assessment of residual chlorine in soil microbial community using metagenomics显示文摘Chlorine-containing disinfectants have been widely used around the world for the prevention and control of the COVID-19 pandemic.However,at present,little is known about the impact of residual chlorine on the soil micro-ecological environment.Herein,we treated an experimental soil-plant-microbiome microcosm system by continuous irrigation with a low concentration of chlorine-containing water,and then analyzed the influence on the soil microbial community using metagenomics.After 14-d continuous chlorine treatment,there were no significant lasting effect on soil microbial community diversity and composition either in the rhizosphere or in bulk soil.Although metabolic functions of the rhizosphere microbial community were affected slightly by continuous chlorine treatment,it recovered to the original status.The abundance of several resistance genes changed by 7 d and recovered by 14 d.According to our results,the chlorine residue resulting from daily disinfection may present a slight long-term effect on plant growth(shoot length and fresh weight)and soil micro-ecology.In general,our study assisted with environmental risk assessments relating to the application of chlorine-containing disinfectants and minimization of risks to the environment during disease control,such as COVID-19. | Yitian Yu Qi Zhang Zhenyan Zhang Nuohan Xu Yan Li Mingkang Jin Guoqiang Feng Haifeng Qian Tao Lu | 2023 | Soil Ecology Letters2023，5，1： | 0 |
| 7 | NICFS:a file system based on persistent memory and SmartNIC显示文摘Emergence of new hardware,including persistent memory and smart network interface card(SmartNIC),has brought new opportunities to file system design.In this paper,we design and implement a new file system named NICFS based on persistent memory and SmartNIC.We divide the file system into two parts:the front end and the back end.In the front end,data writes are appended to the persistent memory in a log-structured way,leveraging the fast persistence advantage of persistent memory.In the back end,the data in logs are fetched,processed,and patched to files in the background,leveraging the processing capacity of SmartNIC.Evaluation results show that NICFS outperforms Ext4 by about 21%/10%and about 19%/50%on large and small reads/writes,respectively. | Yitian YANG Youyou LU | 2023 | Frontiers of Information Technology & Electronic Engineering2023，24，5： | 0 |
| 8 | Epigenetic combined with transcriptomic analysis of the m6A methylome after spared nerve injury-induced neuropathic pain in mice显示文摘Epigenetic changes in the spinal cord play a key role in the initiation and maintenance of nerve injury-induced neuro pathic pain.N6-methyladenosine(m6A)is one of the most abundant internal RNA modifications and plays an essential function in gene regulation in many diseases.However,the global m6A modification status of mRNA in the spinal cord at different stages after neuropathic pain is unknown.In this study,we established a neuropathic pain model in mice by preserving the complete sural nerve and only damaging the common peroneal nerve.High-throughput methylated RNA immunoprecipitation sequencing res ults showed that after spared nerve injury,there were 55 m6A methylated and diffe rentially expressed genes in the spinal cord.Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway results showed that m6A modification triggered inflammatory responses and apoptotic processes in the early stages after spared nerve injury.Over time,the diffe rential gene function at postoperative day 7 was enriched in 'positive regulation of neurogenesis' and 'positive regulation of neural precursor cell prolife ration.' These functions suggested that altered synaptic morphological plasticity was a turning point in neuropathic pain formation and maintenance.Results at postoperative day 14 suggested that the persistence of neuropathic pain might be from lipid metabolic processes,such as 'very-low-density lipoprotein particle clearance,' 'negative regulation of choleste rol transport' and 'membrane lipid catabolic process.' We detected the expression of m6A enzymes and found elevated mRNA expression of Ythdf2 and Ythdf3 after spared nerve injury modeling.We speculate that m6A reader enzymes also have an important role in neuropathic pain.These results provide a global landscape of mRNA m6A modifications in the spinal cord in the spared nerve injury model at diffe rent stages after injury. | Fanning Zeng Jun Cao Zexuan Hong Yitian Lu Zaisheng Qin Tao Tao | 2023 | Neural Regeneration Research2023，18，11： | 0 |
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