|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Antioxidant flavonol glycosides in mulberry ( Morus alba L.) leaves isolated based on LDL antioxidant activity显示文摘 | Takuya Katsube Naoto Imawaka Yasuhiro Kawano Yoshimitsu Yamazaki Kuninori Shiwaku Yosuke Yamane | 2005 | Food Chemistry2005，，1： | 2 |
| 2 | Non-invasive prediction of non-alcoholic steatohepatitis in Japanese patients with morbid obesity by artificial intelligence using rule extraction technology显示文摘AIM To construct a non-invasive prediction algorithm for predicting non-alcoholic steatohepatitis(NASH), we investigated Japanese morbidly obese patients using artificial intelligence with rule extraction technology.METHODS Consecutive patients who required bariatric surgery underwent a liver biopsy during the operation. Standard clinical, anthropometric, biochemical measurements were used as parameters to predict NASH and were analyzed using rule extraction technology. One hundred and two patients, including 79 NASH and 23 non-NASH patients were analyzed in order to create the predictionmodel, another cohort with 77 patients including 65 NASH and 12 non-NASH patients were analyzed to validate the algorithm.RESULTS Alanine aminotransferase, C-reactive protein, homeostasis model assessment insulin resistance, albumin were extracted as predictors of NASH using a recursive-rule extraction algorithm. When we adopted the extracted rules for the validation cohort using a highly accurate rule extraction algorithm, the predictive accuracy was 79.2%. The positive predictive value, negative predictive value,sensitivity and specificity were 88.9%, 35.7%, 86.2% and 41.7%, respectively.CONCLUSION We successfully generated a useful model for predicting NASH in Japanese morbidly obese patients based on their biochemical profile using a rule extraction algorithm. | Daisuke Uehara Yoichi Hayashi Yosuke Seki Satoru Kakizaki Norio Horiguchi Hiroki Tojima Yuichi Yamazaki Ken Sato Kazuki Yasuda Masanobu Yamada Toshio Uraoka Kazunori Kasama | 2018 | World Journal of Hepatology2018，10，12： | 2 |
| 3 | Antioxidant flavonol glycosides in mulberry ( Morus alba L.) leaves isolated based on LDL antioxidant activity显示文摘 | Takuya Katsube Naoto Imawaka Yasuhiro Kawano Yoshimitsu Yamazaki Kuninori Shiwaku Yosuke Yamane | 2005 | Food Chemistry2005，，1： | 2 |
| 4 | Electrospinning processed nanofibmus TiO2 membranes for photoboltaic applications显示文摘 | Katsuhiro Onozuka Bin Ding Yosuke Tsuge Takayuki Naka Michiyo Yamazaki | 2006 | Nanotechnology2006，17，： | 1 |
| 5 | Development of Slit-Type Pressure Differentiator Using an Isothermal Chamber显示文摘 | Kawashima Kenji Kato Tomonori Yamazaki Yosuke | 2005 | Measurement Science and Technology2005，，： | 1 |
| 6 | Identification of genes related to heart failure using global gene expression profiling of human failing myocardium显示文摘 | Kyung-Duk Min Masanori Asakura Yulin Liao Kenji Nakamaru Hidetoshi Okazaki Tomoko Takahashi Kazunori Fujimoto Shin Ito Ayako Takahashi Hiroshi Asanuma Satoru Yamazaki Tetsuo Minamino Shoji Sanada Osamu Seguchi Atsushi Nakano Yosuke Ando Toshiaki Otsuka Hi | 2010 | Biochemical and Biophysical Research Communications2010，，1： | 1 |
| 7 | Combination of branched-chain amino acids and angiotensin-convertingenzyme inhibitor suppresses the cumulative recurrence of hepatocellular carcinoma:A randomized control trial显示文摘 | Hitoshi Yoshiji Ryuichi Noguchi Yasuhide Ikenaka Kosuke Kaji Yosuke Aihara Masaharu Yamazaki Junichi Yamao Masahisa Toyohara Akira Mitoro Masayoshi Sawai Motoyuki Yoshida Chie Morioka Masao Fujimoto Masahito Uemura Hiroshi Fukui | 2011 | Oncology Reports2011，，6： | 1 |
| 8 | A case of severe acalculous cholecystitis associated with sorafenib treatment for advanced hepatocellular carcinoma显示文摘Sorafenib,a multikinase inhibitor,is the first and only drug,which improves significantly the overall survival in patients with advanced hepatocellular carcinoma(HCC).However,many patients experience diverse side effects,some of them severe and unexpected.To date,acute acalculous cholecystitis has not been documented in association with a HCC patient treated with sorafenib.Here,we report the case of a 43-yearold woman with hepatitis C virus-related advanced HCC.She received sorafenib,and later complained ofa sudden onset of severe right hypocondrial pain with rebound tenderness and muscle defense.Laboratory examination showed mild elevation of transaminases,biliary enzymes,bilirubin,inflammation markers,and a marked peripheral eosinophilia.Abdominal computed tomography(CT) revealed a swollen gallbladder with exudate associated with severe inflammation without stones or debris.Consequently,sorafenib treatment was stopped immediately,and steroid-pulse therapy was performed.Steroid therapy drastically improved all clinical manifestations along with normalization of CT findings,eosinophilia,and liver functions.In summary,we herein report a rare case of acute severe acalculous cholecystitis associated with sorafenib in the patient with advanced HCC. | Yosuke Aihara Hitoshi Yoshiji Masaharu Yamazaki Yasuhide Ikenaka Ryuichi Noguchi Chie Morioka Kosuke Kaji Haruki Tastumi Keisuke Nakanishi Maiko Nakamura Junichi Yamao Masahisa Toyohara Akira Mitoro Masayoshi Sawai Motoyuki Yoshida Masao Fujimoto Masahito Uemura Hiroshi Fukui | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 1 |
| 9 | Evaluation of preferable insertion routes for esophagogastroduodenoscopy using ultrathin endoscopes显示文摘AIM:To evaluate the discomfort associated with esophagogastroduodenoscopy(EGD)using an ultrathin endoscope through different insertion routes.METHODS:This study(January 2012-March 2013)included 1971 consecutive patients[male/female(M/F),1158/813,57.5±11.9 years]who visited a single institute for annual health checkups.Transnasal EGD was performed in 1394 patients and transoral EGD in 577.EGD-associated discomfort was assessed using a visual analog scale score(VAS score:0-10).RESULTS:Multivariate analysis revealed gender(M vs F:4.02±2.15 vs 5.06±2.43)as the only independent predictor of the VAS score in 180 patients who underwent EGD for the first time;whereas it revealed gender(M vs F 3.60±2.20 vs 4.84±2.37),operator,age group(A:<39 years;B:40-49 years;C:50-59years;D:60-69 years;E:>70 years;A/B/C/D/E:4.99±2.32/4.34±2.49/4.19±2.31/3.99±2.27/3.63±2.31),and type of insertion as independent predictors in the remaining patients.Subanalysis for gender,age group,and insertion route revealed that the VAS score decreased with age regardless of gender and insertion route,was high in female patients regardless of age and insertion route,and was low in males aged over60 years who underwent transoral insertion.CONCLUSION:Although comprehensive analysis revealed that the insertion route may not be an independent predictor of the VAS score,transoral insertion may reduce EGD-associated discomfort in elderly patients. | Satoshi Ono Keiko Niimi Mitsuhiro Fujishiro Yu Takahashi Yoshiki Sakaguchi Chiemi Nakayama Chihiro Minatsuki Rie Matsuda Itsuko Hirayama-Asada Yosuke Tsuji Satoshi Mochizuki Shinya Kodashima Nobutake Yamamichi Atsuko Ozeki Lumine Matsumoto Yumiko Ohike Tsutomu Yamazaki Kazuhiko Koike | 2014 | World Journal of Gastroenterology2014，20，17： | 0 |
| 10 | Horizontal structure of convergent wind shear associated with sporadic E layers over East Asia显示文摘At present,the main detection instruments for observing sporadic E(Es)layers are ground-based radars,dense networks of ground-based global navigation satellite system(GNSS)receivers,and GNSS radio occultation,but they cannot capture the whole picture of the horizontal structure of Es layers.This study employs the Whole Atmosphere Community Climate Model with thermosphere and ionosphere eXtension model(WACCM-X 2.1)to derive the horizontal structure of the ion convergence region(HSICR)to explore the shapes of the large-scale Es layers over East Asia for the period from June 1 to August 31,2008.The simulation produced the various shapes of the HSICRs elongated in the northwest-southeast,northeast-southwest,or composed of individual small patches.The close connection between Es layer critical frequency(foEs)and vertical ion convergence indicates that the HSICR is a good candidate for revealing and explaining the horizontal structure of the large-scale Es layers. | LiHui Qiu Xian Lu Tao Yu Yosuke Yamazaki HuiXin Liu Yang-Yi Sun HaoNan Wu XiaoMin Zuo XiangXiang Yan Yan Yu YiFan Qi | 2023 | Earth and Planetary Physics2023，7，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员