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| 1 | 苹果轮纹病菌侵染机制的研究(英文)显示文摘苹果轮纹病菌(Botryosphaeriaberengrianaf.sppiricola)能在培养基及活体内产生一系列果胶酶:多聚半乳糖醛酸酶(PG)、聚甲基半乳糖醛酸酶(PMG)、多聚半乳糖醛酸反式消除酶(PGTE)和果胶甲基反式消除酶(PMTE)。其中PG和PMG是降解果实胞壁的主要酶类,在整个致病过程中起重要作用。从结果可看出PG活性随着侵染的进展而升高,PMG的作用在侵染前期更大一些,2种果胶酶可能是引起被接种苹果果皮上还原糖变化的重要因素。接种与未接种果实果皮的pH值差异随侵染进程而降低,接种40d后,接种处pH值开始低于健康组织的pH值,这一变化可能造成细胞壁软化而有利于PG和PMG活动。接种后10~20d,PG活性及组织中还原糖的增长速度比其他阶段要快。对侵染点的病原组织学研究进一步表明,病菌产生的各种果胶酶不论是在侵染初期还是后期都是重要的致病物质。 | 李广旭 沈永波 高艳敏 陈杰 Jie Youl Uhm | 2007 | 果树学报2007，24，1： | 33 |
| 2 | Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression显示文摘目的:在这研究,我们在各种各样的煽动性的事件上调查了 honokiol 的规章的效果由单核白血球/巨噬细胞( U937/RAW264.7 房间)和淋巴细胞(脾的淋巴细胞和 CTLL-2 房间)和他们的通常认为的行动 mechanism.Methods 调停了:以便调查规章的效果,各种各样的房间线和原电池( U937 , RAW264.7 , CTLL-2 房间,和脾的淋巴细胞)被采用,各种各样的煽动性的事件例如煽动性的调停人,房间粘附,房间增长,和早发信号的串联的生产,是 chosen.Results : Honokiol 强烈禁止了各种各样的煽动性的回答,例如:(i)起来氮的氧化物的规定(没有),前列腺素 E_2 和 TNF-alpha 生产和 costimulatory 分子 CD80 由脂肪的多糖( LPS )导致了;( i i )贝它 1-integrin ( CD29 )的功能的激活由 U937 房间房间和 cell-fibronectin 粘附估计了;( iii )淋巴细胞和 CD8+CTLL-2 房间增长的改进由 LPS 刺激了, phytohemaglutinin A (公众房产管理局),和刀豆球蛋白 A 或 interleukin ( IL )在规定上面的 -2;and(iv)the transcriptional 可诱导没有 synthase , TNF-alpha , cyclooxygenase-2 , IL-12 ,并且单核白血球 chemoattractant 蛋白质( MCP ) -1.These honokiol 的反煽动性的效果似乎被打断早激活的细胞内部的发信号的分子 phosphoinositide 3-kinase ( PI3K )调停 /Akt ,然而并非 Src ,细胞外的调整信号的激酶,和 p38 根据药理学,生物化学,并且功能的 analyses.Conclusion :这些结果建议 honokiol 可以在 PI3K/Akt 小径上由于禁止的效果与多潜在的活动作为一个有势力扮演反煽动性的代理人。 | Byung Hun KIM Jae Youl CHO | 2008 | Acta Pharmacologica Sinica2008，29，1： | 18 |
| 3 | Commissioning progress of the FAST显示文摘The Five-hundred-meter Aperture Spherical radio Telescope(FAST) was completed with its main structure installed on September 25, 2016, after which it entered the commissioning phase. This paper aims to introduce the commissioning progress of the FAST over the past two years. To improve its operational reliability and ensure effective observation time, FAST has been equipped with a real-time information system for the active reflector system and hierarchical commissioning scheme for the feed support system, which ultimately achieves safe operation of the two systems. For meeting the high-performance indices, a highprecision measurement system was set up based on the effective control methods that were implemented for the active reflector system and feed support system. Since the commissioning of the FAST, a low-frequency ultra-wideband receiver and 19-beam1.05-1.45 GHz receiver have been mainly used. Telescope efficiency, pointing accuracy, and system noise temperature were completely tested and ultimately achieved the acceptance indices of the telescope. The FAST has been in the process of national acceptance preparations and has begun to search for pulsars. In the future, it will still strive to improve its capabilities and expand its application prospects. | Peng Jiang YouLing Yue HengQian Gan Rui Yao Hui Li GaoFeng Pan JingHai Sun DongJun Yu HongFei Liu NingYu Tang Lei Qian JiGuang Lu Jun Yan Bo Peng ShuXin Zhang QiMing Wang Qi Li Di Li | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，5： | 11 |
| 4 | Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics显示文摘 | Jean-Claude Martinou Richard J. Youle | 2011 | Developmental Cell2011，，1： | 6 |
| 5 | Effects of drought stress on root morphology and spatial distribution of soybean and adzuki bean显示文摘Due to global climate change,Korea is facing severe droughts that affect the planting and early vegetative periods of upland crops.Soybean and adzuki bean are important legume crops in Korea,so it is critical to understand their adaptations to water stress.This study investigated the changes in root morphological properties in soybean and adzuki bean and quantified the findings using fractal analysis.The experiment was performed at the National Institute of Crop Science in Miryang,Korea.Soybeans and adzuki beans were planted in test boxes and grown for 30 days.The boxes were filled with bed soil with various soil moisture treatments.Root images were obtained and scanned every two days,and the root properties were characterized by root length,depth and surface area,number of roots,and fractal parameters(fractal dimension and lacunarity).Root depth,length and surface area and the number of roots increased in both crops as the soil moisture content increased.The fractal dimension and lacunarity values increased as the soil moisture content increased.These results indicated that the greater the soil moisture,the more heterogeneous the root structure.Correlation analysis of the morphological properties and fractal parameters indicated that soybean and adzuki bean had different root structure developments.Both soybean and adzuki bean were sensitive to the amount of soil moisture in the early vegetative stage.Soybean required a soil moisture content greater than 70%of the field capacity to develop a full root structure,while adzuki bean required 100%of the field capacity.These results would be useful in understanding the responses of soybean and adzuki bean to water stress and managing irrigation during cultivation. | Hyen Chung CHUN Sanghun LEE Young Dae CHOI Dong Hyeok GONG Ki Youl JUNG | 2021 | Journal of Integrative Agriculture2021，20，10： | 5 |
| 6 | Cross-regulation between protein L-isoaspartyl O-methyltransferase and ERK in epithelial mesenchymal transition of MDA-MB-231 cells显示文摘目的: 蛋白质 L-isoaspartyl O-methyltransferase (PIMT ) 通过 integrin α 的激活在各种各样的癌症房间线调整房间粘附; v 和 PI3K 小径。上皮的间充质的转变(EMT ) 使上皮的房间能获得间充质的房间的特征,并且允许他们为转移移居。这里,我们与依附或分开的 MDA-MB 231 房间检验了在 PIMT 和 EMT 之间的关系。 | Jiyeon RYU Jihyeok SONG Jieun HEO Yongwoo JUNG Sang-Jin LEE Sungyoul HONG Jae Youl CHO | 2011 | Acta Pharmacologica Sinica2011，32，9： | 5 |
| 7 | The first pulsar discovered by FAST显示文摘To assist with the commissioning [1] of the Five-hundredmeter Aperture Spherical radio Telescope (FAST), we performed a pulsar search, with the primary goal of developing and testing the pulsar data acquisition and processing pipelines. We tested and used three pipelines, two (Pl and P2 hereafter) searched for the periodic signature of pulsars whereas the other one was used to search for bright single pulses (P3 hereafter). | Lei Qian ZhiChen Pan Di Li George Hobbs WeiWei Zhu Pei Wang ZhiJie Liu YouLing Yue Yan Zhu HongFei Liu DongJun Yu JingHai Sun Peng Jiang GaoFeng Pan Hui Li HengQian Gan Rui Yao XiaoYao Xie Fernando Camilo Andrew Cameron Lei Zhang Shen Wang FAST Collaboration | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，5： | 3 |
| 8 | Antioxidant activity of peptide fractions from whey protein hydrolysates as measured by electron spin resonance显示文摘 | Xinyan Peng Youling L. Xiong Baohua Kong | 2008 | Food Chemistry2008，，1： | 2 |
| 9 | The effect of protein oxidation on hydration and water-binding in pork packaged in an oxygen-enriched atmosphere显示文摘 | Rebecca M. Delles Youling L. Xiong | 2014 | Meat Science2014，，： | 2 |
| 10 | Rheology and microstructure of myofibrillar protein–plant lipid composite gels: Effect of emulsion droplet size and membrane type显示文摘 | Mangang Wu Youling L. Xiong Jie Chen | 2011 | Journal of Food Engineering2011，，4： | 2 |
| 11 | Resveratrol attenuates the expression of HMG-CoA reductase mRNA in hamsters显示文摘 | Il Jin Cho Ji Yun Ahn Suna Kim Myung Sook Choi Tae Youl Ha | 2007 | Biochemical and Biophysical Research Communications2007，，1： | 2 |
| 12 | Bcl-x L Retrotranslocates Bax from the Mitochondria into the Cytosol显示文摘 | Frank Edlich Soojay Banerjee Motoshi Suzuki Megan M. Cleland Damien Arnoult Chunxin Wang Albert Neutzner Nico Tjandra Richard J. Youle | 2011 | Cell2011，，1： | 2 |
| 13 | Radical scavenging activity of black currant ( Ribes nigrum L.) extract and its inhibitory effect on gastric cancer cell proliferation via induction of apoptosis显示文摘 | Na Jia Youling L. Xiong Baohua Kong Qian Liu Xiufang Xia | 2012 | Journal of Functional Foods2012，，1： | 2 |
| 14 | Control of mitochondrial permeability by Bcl-2 family members显示文摘 | SHARPE J C AMOULTT D YOULE R J | 2004 | Biochim Biophys Acta2004，1644，23： | 1 |
| 15 | Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics 显示文摘 | Martinou JC Youle ILl | 2011 | Dev Cell2011，21，1： | 1 |
| 16 | The efficacy and toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex (ARC):an open uncontrolled treatment study显示文摘 | Stambuk D Youle M Hawkins D | | 0，，262： | 1 |
| 17 | Mitochondrial dynamics and apoptosis 显示文摘 | SUEN D F NORRIS K L YOULE R J | 2008 | Genes Dev2008，22，12： | 1 |
| 18 | A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: the UK-Vanguard Study 显示文摘 | Youle M Emery S Fisher M | 2006 | PLoS Chp Trials2006，1，1： | 1 |
| 19 | The BCL-2 protein family:opposing activities that mediate cell death显示文摘 | Youle RJ Strasser A | 2008 | Nat Rev Mol Cell Biol2008，9，1： | 1 |
| 20 | Cytotoxic ribonucleases and chimeras in cancer therapy显示文摘 | Youle RJ Newton D Wu YN | 1993 | Crit Rev Ther Drug Carrier Syst1993，10，1： | 1 |
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