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| 1 | Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice显示文摘最近的研究开始在心脏的肥大和机能障碍的致病揭示了 microRNAs (miRNAs ) 的关键角色。在这研究,我们测试了是否转变生长 factor-β(TGF-β) 调整 miRNA 在心脏的肥大和心失败(HF ) 的发展起了一个枢轴的作用。我们观察到 miR-27b 是在 cardiomyocyte 特定的 Smad4 猛烈老鼠的心的 upregulated,它开发了心脏的肥大。在 vitro,实验证明 miR-27b 表示能被 TGF-β 禁止; 1 并且它的 overexpression 支持了 hypertrophic 房间生长,当 miR-27b 抑制导致了 hypertrophic 房间的抑制时,生长由 phenylephrine (PE ) 引起了处理。而且,有 miR-27b 的 cardiomyocyte 特定的 overexpression 的转基因的老鼠的分析表明 miR-27b overexpression 是足够的导致心脏的肥大和机能障碍。我们验证了 peroxisome 激活 proliferator 的 receptor-γ(PPAR-γ) 作为在 cardiomyocyte 的 miR-27b 的一个直接目标。一致地, miR-27b 转基因的老鼠显著地显示了 PPAR-γ 的底层;比控制鼠标。而且,在用在一只 pressure-overload-induced 老鼠的特定的 antagomir 的 miR-27b 的 vivo silencing, HF 的模型增加了心脏的 PPAR-γ表示,稀释心脏的肥大和机能障碍。我们的学习的结果表明那 TGF-β 1-regulated miR-27b 涉及心脏的肥大的规定,并且为心脏病作为一个有效治疗学的目标验证 miR-27b。 | Jian Wang Yao Song Yan Zhang Han Xiao Qiang Sun Ning Hou Shuilong Guo Youliang Wang Kaiji Fan Dawei Zhan Lagabaiyila Zha Yang Cao Zhenhua Li Xuan Cheng Youyi Zhang Xiao Yang | 2012 | Cell Research2012，22，3： | 36 |
| 2 | OPTIMAL RESERVE PRICE IN STATIC AND DYNAMIC SPONSORED SEARCH AUCTIONS显示文摘Sponsored search advertising is a significant revenue source for search engines.To ameliorate revenues,search engines often set fixed or variable reserve price to in influence advertisers' bidding. This paper studies the optimal reserve price for a generalized second-price auction(GSP) under both static and dynamic settings.We show that if advertisers' per-click value has an increasing generalized failure rate,the search engine's revenue rate is quasi-concave and hence there exists an optimal reserve price under both settings.Different from a static GSP auction where the optimal reserve price is proved to be constant,in a dynamic setting the optimal reserve price is dependent on not only advertisers' per-click values,but also the number of ad links sold.A search engine should gradually raise reserve price as more qualified advertisers arrive,and maintain the same threshold after all first-page positions are occupied. | Wei YANG Jun QIAO Youyi FENG Baichun XIAO | 2013 | Journal of Systems Science and Systems Engineering2013，22，4： | 2 |
| 3 | Nonlinear optical properties of silver colloidal solution by in situ synthesis technique显示文摘 | Yan Deng Youyi Sun Pei Wang Douguo Zhang Xiaojin Jiao Hai Ming Qijing Zhang Yang Jiao Xiaoquan Sun | 2007 | Current Applied Physics2007，，： | 1 |
| 4 | Control synthesis of continuous-time T-S fuzzy sys- tems with local nonlinear models 显示文摘 | DONG Jiuxiang WANG Youyi YANG Guanghong | 2009 | IEEE Trans- actions on Systems Man and Cybernetics-Part B: Cybernetics2009，39，5： | 1 |
| 5 | 子宫内膜间质肉瘤保留生育功能治疗体会(英文)显示文摘The paper introduced the experience of a case of recurrence of endometrial stromal sarcoma with fertility conservation treatment after full-term delivery. A 24-year-old unmarried patient who, with her increasing amount of menstruation in the late six months, had a mass in her lower-abdominal which was confirmed by B-ultrasonic diagnosis as myometrium mixed mass, was given an enucleation of uterus tumor. The pathological examination of tumor sample revealed it as lowgrade endometrial stromal sarcoma (LESS). And the patient underwent 6 cycles of chemotherapy over 8 months before she got pregnant and had a full-term delivery. But in 34 months after delivery, the disease recurred with metastatic of pelvic and peritoneal cavity and the patient had to receive comprehensive therapy. Conclusion: The unmarried young patient with stage I low-grade endometrial stromal sarcoma has the chance to preserve uterus for her pregnancy and delivery. But the using of cesarean needs do staging operation and prognosis evaluation. | Dajun Xiang Youyi Yang Hua Zhao | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，9： | 1 |
| 6 | Lower Triassic peritidal cyclic limestone: an example of anachronistic carbonate facies from the Great Bank of Guizhou, Nanpanjiang Basin, Guizhou province, South China显示文摘 | Daniel J Lehrmann Yang Wan Jiayong Wei YouYi Yu Jiafei Xiao | 2001 | Palaeogeography Palaeoclimatology Palaeoecology2001，，3： | 1 |
| 7 | 新加坡中央医院针灸门诊的规范化管理显示文摘介绍新加坡中央医院针灸门诊的规范化管理。通过对门诊基础建设逐渐改进,医务人员再培训,操作过程严格消毒,医疗仪器定期检查,病历书写、保存和处理统一管理,开展公众中医知识教育等,逐渐形成了一套与现代化医院相适应的规范化管理制度,使临床治疗效率和质量不断提高。自1998年4月至2012年12月,治疗患者74 654人次,日诊量渐增,避免了针灸异常状况的发生,多次通过国内外国际医疗卫生机构认证联合委员会定期的严格审查。此外,针灸门诊还承担了3项新加坡健保集团的科研项目。 | 崔淑丽 Tan Kian Hian Ong Biauw Chi Lim Shih hui Yong Yang Seah Cheng Ngee Youyi Huang Han Seong Ng | 2014 | 中国针灸2014，34，2： | 0 |
| 8 | An interactive approach for functional prototype recovery from a single RGBD image显示文摘Inferring the functionality of an object from a single RGBD image is difficult for two reasons:lack of semantic information about the object, and missing data due to occlusion. In this paper, we present an interactive framework to recover a 3D functional prototype from a single RGBD image.Instead of precisely reconstructing the object geometry for the prototype, we mainly focus on recovering the object's functionality along with its geometry.Our system allows users to scribble on the image to create initial rough proxies for the parts. After user annotation of high-level relations between parts, our system automatically jointly optimizes detailed joint parameters(axis and position) and part geometry parameters(size, orientation, and position). Such prototype recovery enables a better understanding of the underlying image geometry and allows for further physically plausible manipulation. We demonstrate our framework on various indoor objects with simple or hybrid functions. | Yuliang Rong Youyi Zheng Tianjia Shao Yin Yang Kun Zhou | 2016 | Computational Visual Media2016，2，1： | 0 |
| 9 | Radioanalytical chemistry for nuclear forensics in China:Progress and future perspective显示文摘A relatively new branch of science-nuclear forensics,aiming at providing the nature,origin,history and possible trafficking route of seized nuclear materials/devices,has been established and rapidly developed over decades to screen illicit nuclear activities.This highly interdisciplinary science is built upon a foundation of analytical chemistry,radiochemistry,nuclear physics,material sciences,geology,and other scientific disciplines,within which radiochemical methodologies and radioanalytical techniques play a key role.The present review provides a brief overview about the crucial aspects of nuclear forensics,including basic content,procedure,concerned elements,common separation,analytical method,and so on.The state of the art and recent progresses of nuclear forensics by research communities in China are reviewed,while selected examples and practical applications are emphasized.The challenges associated with this new area and on-going developments are highlighted and discussed. | Yi Liu Xuepeng Shao Wenting Bu Zhen Qin Youyi Ni Fengcheng Wu Chuting Yang Xiaolin Wang | 2022 | Chinese Chemical Letters2022，33，7： | 0 |
| 10 | An LCC-HVDC Adaptive Emergency Power Support Strategy Based on Unbalanced Power On-Line Estimation显示文摘HVDC auxiliary power control can significantly improve the transient stability of AC/DC power grid.An HVDC adaptive emergency power support method based on unbalanced power on line estimation is proposed in this paper.By establishing the extended state equation of the system,the on line dynamic estimation of unbalanced power of the system was realized.On this basis,power support was realized based on the principle of the ladder increment.The optimal DC was selected by the power support factor,and the emergency power support controller was installed on the DC.This emergency power support method can realize dynamic optimal power support with minimized control cost.The three infeed HVDC system was built on PSCAD.The simulation results show the effectiveness of the proposed method. | Congshan Li Jian Guo Ping He Yukun Tao Cunxiang Yang Youyi Wang | 2020 | Journal of Harbin Institute of Technology(New Series)2020，27，2： | 0 |
| 11 | iHair Recolorer: deep image-to-video hair color transfer显示文摘In this paper, we present i Hair Recolorer, the first deep-learning based approach for examplebased hair color transfer in videos. Given an input video and a reference image, our method automatically transfers the hair color in the reference image to the hair in the video while keeping other hair attributes(e.g.,shape, structure, and illumination) untouched, producing vivid color-transferred dynamic hair in the video.Our method performs the color transfer purely in the image space, without any form of intermediate 3 D hair reconstruction. The key enabler of our method is a carefully designed conditional generative model that explicitly disentangles various hair attributes into their corresponding sub-spaces, which are implemented as conditional modules integrated into a generator. We introduce a novel spatially and temporally normalized luminance map to represent the structure and illumination of the hair. Such a representation can largely ease the burden of the generator to synthesize temporally coherent vivid dynamic hairs in the video. We further introduce a cycle consistency loss to enforce the faithfulness of the generated results with respect to the reference. We demonstrate our system’s superiority in video hair color transfer by extensive experiments and comparisons to alternative methods. | Keyu WU Lingchen YANG Hongbo FU Youyi ZHENG | 2021 | Science China(Information Sciences)2021，64，11： | 0 |
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