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| 1 | Identification of a novel HMW glutenin subunit and comparison of its amino acid sequence with those of homologous subunits显示文摘Aegilops tauschii is the donor of the D genome of common wheat (Triticum aestivum). Genetic variation of HMW glutenin subunits encoded by the Glu-1Dt locus of Ae. tauschii has been found to be higher than that specified by the Glu-1D locus in common wheat. In the present note, we report the identification of a novel HMW glutenin subunit, Dy13t, from Ae. tauschii. The newly identified subunit pos-sessed an electrophoretic mobility that was faster than that of the Dy12 subunit of common wheat. The complete ORF of encoding the Dy13t subunit contained 624 codons (excluding the stop codons). The amino acid sequence deduced from the Dy13t gene ORF was the shortest among those of the previ-ously reported subunits derived by the D genome. A further comparison of Dy13t amino acid sequence with those of the subunits characterized from the A, B, D, R genomes of Triticeae showed that the smaller size of the Dy13t subunit was associated with a reduction in the size of its repetitive domain. | YAN Zehong WAN Yongfang LIU Kunfan ZHENG Youliang WANG Daowen | 2002 | Chinese Science Bulletin2002，47，3： | 60 |
| 2 | Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice显示文摘最近的研究开始在心脏的肥大和机能障碍的致病揭示了 microRNAs (miRNAs ) 的关键角色。在这研究,我们测试了是否转变生长 factor-β(TGF-β) 调整 miRNA 在心脏的肥大和心失败(HF ) 的发展起了一个枢轴的作用。我们观察到 miR-27b 是在 cardiomyocyte 特定的 Smad4 猛烈老鼠的心的 upregulated,它开发了心脏的肥大。在 vitro,实验证明 miR-27b 表示能被 TGF-β 禁止; 1 并且它的 overexpression 支持了 hypertrophic 房间生长,当 miR-27b 抑制导致了 hypertrophic 房间的抑制时,生长由 phenylephrine (PE ) 引起了处理。而且,有 miR-27b 的 cardiomyocyte 特定的 overexpression 的转基因的老鼠的分析表明 miR-27b overexpression 是足够的导致心脏的肥大和机能障碍。我们验证了 peroxisome 激活 proliferator 的 receptor-γ(PPAR-γ) 作为在 cardiomyocyte 的 miR-27b 的一个直接目标。一致地, miR-27b 转基因的老鼠显著地显示了 PPAR-γ 的底层;比控制鼠标。而且,在用在一只 pressure-overload-induced 老鼠的特定的 antagomir 的 miR-27b 的 vivo silencing, HF 的模型增加了心脏的 PPAR-γ表示,稀释心脏的肥大和机能障碍。我们的学习的结果表明那 TGF-β 1-regulated miR-27b 涉及心脏的肥大的规定,并且为心脏病作为一个有效治疗学的目标验证 miR-27b。 | Jian Wang Yao Song Yan Zhang Han Xiao Qiang Sun Ning Hou Shuilong Guo Youliang Wang Kaiji Fan Dawei Zhan Lagabaiyila Zha Yang Cao Zhenhua Li Xuan Cheng Youyi Zhang Xiao Yang | 2012 | Cell Research2012，22，3： | 36 |
| 3 | Weak Orlicz space and its applications to the martingale theory显示文摘In this paper,the weak Orlicz space wL Φ is introduced and its applications to the martingale theory are discussed.In particular,a series of martingale inequalities including the maximal function inequality in weak Orlicz spaces are established;the relationships between these spaces are investigated.Moreover,the boundedness of several sublinear operators from one weak Orlicz space to another is proved;their vector-valued analogues are also considered. | LIU PeiDe,HOU YouLiang & WANG MaoFa School of Mathematics and Statistics,Wuhan University,Wuhan 430072,China | 2010 | Science China Mathematics2010，53，4： | 21 |
| 4 | Analysis and assessment of bridge health monitoring mass data——progress in research/development of “Structural Health Monitoring”显示文摘The 'Structural Health Monitoring' is a project supported by National Natural Science Foundation for Distinguished Young Scholars of China(Grant No.50725828).To meet the urgent requirements of analysis and assessment of mass monitoring data of bridge environmental actions and structural responses,the monitoring of environmental actions and action effect modeling methods,dynamic performance monitoring and early warning methods,condition assessment and operation maintenance methods of key members are systematically studied in close combination with structural characteristics of long-span cable-stayed bridges and suspension bridges.The paper reports the progress of the project as follows.(1) The environmental action modeling methods of long-span bridges are established based on monitoring data of temperature,sustained wind and typhoon.The action effect modeling methods are further developed in combination with the multi-scale baseline finite element modeling method for long-span bridges.(2) The identification methods of global dynamic characteristics and internal forces of cables and hangers for long-span cable-stayed bridges and suspension bridges are proposed using the vibration monitoring data,on the basis of which the condition monitoring and early warning methods of bridges are developed using the environmental-condition-normalization technique.(3) The analysis methods for fatigue loading effect of welded details of steel box girder,temperature and traffic loading effect of expansion joint are presented based on long-term monitoring data of strain and beam-end displacement,on the basis of which the service performance assessment and remaining life prediction methods are developed. | LI AiQun DING YouLiang WANG Hao GUO Tong | 2012 | Science China(Technological Sciences)2012，55，8： | 14 |
| 5 | Discoloration mechanism,structures and recent applications of thermochromic materials via different methods:A review显示文摘Thermochromic material is a kind of smart material whose color will vary as the result of the phase transition caused by the temperature change. The characteristics of thermochromic materials are the memory functions to the temperature, having great potential applications in aerospace, military, anticounterfeiting technology, construction and other fields. In recent years, many kinds of thermochromic materials have been prepared by different methods and their discoloration mechanisms are various according to published literatures. In this paper, the classification, discoloration mechanism, preparation methods, application fields and development trend of thermochromic materials are reviewed. | Youliang Cheng Xiaoqiang Zhang Changqing Fang Jing Chen Zhen Wang | 2018 | Journal of Materials Science & Technology2018，34，12： | 12 |
| 6 | Pore throat characteristics of tight sandstone of Yanchang Formation in eastern Gansu,Ordos Basin显示文摘An important factor to evaluate reservoir quality is the pore-throat size.However,the strong heterogeneity makes it difficult to characterize the pore-throat distribution in tight reservoirs.The field emission scanning electron microscope(FESEM),high pressure mercury injection and rate-controlled mercury injection are used to investigate the pore-throat size distribution in tight sandstone reservoirs of Member 7 of the Yanchang Formation in eastern Gansu,Ordos Basin,and studies of the pore throat size controlling on physical property of the tight sandstone reservoirs are also carried out.The result shows that the pore type is mainly dominated by the residual intergranular pore,dissolution pore,micropore and a few micro-fractures;the high-pressure mercury injection experiment indicates that the pore-throat size ranges from 0.0148 μm to 40mm,the pore throat more than 1 mm is less;the ratecontrolled mercury injection experiment reveals that for samples with different physical properties,the pore radius mainly varies from 80 μm to 350 μm;the throat radius exhibits the strong heterogeneity,and is from 0.12 μm to 30μm;the pore-throat size can be effectively characterized by combination of high-pressure and rate-controlled mercury injections,and it varies from 0.0148 μm to 350 μm.The permeability is mainly controlled by the large pore throat(>R_(50))which accounts for a small proportion;in the tight sandstone with the permeability greater than 0.1 mD,the permeability is mainly controlled by the micropore and mesopore;in the tight sandstone with the permeability smaller than 0.1 mD,the permeability is mainly controlled by the nanopore and micropore;the proportion of small pore throat increases with reduction of permeability,it is important that the small pore throat influences the reservoir storage property though its effect on permeability are small. | Hao Wu Chunlin Zhang Youliang Ji Rui'e Liu Shang Cao Sheng Chen Yunzhao Zhang Ye Wang Wei Du Gang Liu | 2018 | Petroleum Research2018，3，1： | 7 |
| 7 | Preparation of long-branched polyethylene by in situ poly-merization using late transition metal and metallocene catalysts显示文摘An in situ polymerization method was investigated to prepare long-branched polyethylene (LBPE) with ethylene alone and a single cocatalyst, methylalumoxane (MAO), by using a dual functional catalytic system containing late transition metal oligomerization catalyst and metal-locene copolymerization catalyst. The obtained long-branched polyethylene has the characteristics of low melting point, high activity and well-dispersed sequence distribution. | LIU Zhongyang GUO Cunyue MAZhi WANG Jun XU Demin HE Dawei HU Youliang | 2001 | Chinese Science Bulletin2001，46，24： | 5 |
| 8 | Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis显示文摘Silicosis is a leading cause of occupational disease-related morbidity and mortality worldwide,but the molecular basis underlying its development remains unclear.An accumulating body of evidence supports gasdermin D(GSDMD)-mediated pyroptosis as a key component in the development of various pulmonary diseases.However,there is little experimental evidence connecting silicosis and GSDMD-driven pyroptosis.In this work,we investigated the role of GSDMD-mediated pyroptosis in silicosis.Single-cell RNA sequencing of healthy and silicosis human and murine lung tissues indicated that GSDMD-induced pyroptosis in macrophages was relevant to silicosis progression.Through microscopy we then observed morphological alterations of pyroptosis in macrophages treated with silica.Measurement of interleukin-1βrelease,lactic dehydrogenase activity,and real-time propidium iodide staining further revealed that silica induced pyroptosis of macrophages.Additionally,we verified that both canonical(caspase-1-mediated)and non-canonical(caspase-4/5/11-mediated)signaling pathways mediated silica-induced pyroptosis activation,in vivo and in vitro.Notably,Gsdmd knockout mice exhibited dramatically alleviated silicosis phenotypes,which highlighted the pivotal role of pyroptosis in this disease.Taken together,our results demonstrated that macrophages underwent GSDMD-dependent pyroptosis in silicosis and inhibition of this process could serve as a viable clinical strategy for mitigating silicosis. | Meiyue Song Jiaxin Wang Youliang Sun Junling Pang Xiaona Li Yuan Liu Yitian Zhou Peiran Yang Tianhui Fan Ying Liu Zhaoguo Li Xianmei Qi Baicun Li Xinri Zhang Jing Wang Chen Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 5 |
| 9 | QTL mapping for grain number per spikelet in wheat using a high-density genetic map显示文摘Grain number per spikelet (GNS) is a key determinant of grain yield in wheat.A recombinant inbred line population comprising 300 lines was developed from a cross between a high GNS variety H461 and Chinese Spring from which the reference genome assembly of bread wheat was obtained.Both parents and the recombinant inbred lines were genotyped using the wheat 55K single nucleotide polymorphism(SNP) array.A high-density genetic map containing 21,197 SNPs was obtained.These markers covered each of the 21 chromosomes with a total linkage distance of 3792.71 c M.Locations of these markers in this linkage map were highly consistent with their physical locations in the genome assembly of Chinese Spring.The two parents and the whole RIL population were assessed for GNS in two consecutive years at two different locations.Based on multi-environment phenotype data and best liner unbiased prediction values,three quantitative trait loci (QTL) for GNS were identified.One of them located on chromosomes 2B and the other two on 2D.Phenotypic variation explained by these loci varied from 3.07%to26.57%.One of these QTL,QGns.sicau-2D-2,was identified in each of all trials conducted.Based on the best linear unbiased prediction values,this locus explained 19.59%–26.57%of phenotypic variation.A KASP(Kompetitive Allele-Specific PCR) marker closely linked with this locus was generated and used to validate the effects of this locus in three different genetic backgrounds.The identified QTL and the KASP marker developed for it will be highly valuable in fine-mapping the locus and in exploiting it for markerassisted selection in wheat breeding programs. | Yu Lin Xiaojun Jiang Haiyan Hu Kunyu Zhou Qing Wang Shifan Yu Xilan Yang Zhiqiang Wang Fangkun Wu Shihang Liu Caixia Li Mei Deng Jian Ma Guangdeng Chen Yuming Wei Youliang Zheng Yaxi Liu | 2021 | The Crop Journal2021，9，5： | 4 |
| 10 | Synthesis of waterborne polyurethane using snow as dispersant:Structures and properties controlled by polyols utilization显示文摘waterborne polyurethane (WPU) dispersions have gained attention towards environm entally-friendly synthesis. In this article, a series of waterborne polyurethane em ulsions was successfully synthesized and extensively characterized in terms of thermal, mechanical properties, hydrophilic behavior and morphology. Snowwas chosen as dispersant instead of comm only used water. Preparation param eters such as intrinsic properties and molecular weight of polyols were discussed systematically. A chain structure was confirmed by Fourier transform infrared (FT-IR) spectroscopy. when com paring the nature of the polyols (PPG, PEG and PNA, 2000g/mol) of this study, as-synthesized polyether waterborne polyurethane provided higher solid content, viscosity and water-resistance. However, polyester waterborne polyurethane perform ed differently and it exhibited higher therm al stability and crystallinity. When com paring the samples (WPU-N210, WPU-N220, WPU-N230 and WPU-N240) with different molecular weight of the same polyol (PPG) used as soft segment, the emulsion WPU-N220 with molecular weight of 2000g/mol PPG provided the highest solid content and lowest viscosity. It was observed th at particle size was uniform and highly dispersed for all sam ples from TEM images. Therm ogravim etric, differential scanning calorim etry (DSC) and X-ray diffraction results dem onstrated that the emulsion WPU-N230 with m olecular weight of 3000 g/mol PPG possessed higher therm al stability and crystallinity than the other samples. The reason was that the Tg and thermal stability were increased with increasing molecular weight. when molecular weight increased, the arrangem ent of soft segm ent became more regular and so did the regularity of the molecular chains. This work demonstrated that different polyols as soft segment applied could lead to great differences in the structure and property of the resulting WPU. | Changqing Fang Shaofei Pan Zhen Wang Xing Zhou Wanqing Lei Youliang Cheng | 2019 | Journal of Materials Science & Technology2019，35，7： | 4 |
| 11 | Mechanical Characteristics and Mechanism of Granite Subjected to Coupling Effect of Acidic Corrosion and Freeze-Thaw Cycles显示文摘The typical climatic and environmental conditions in Central Asia are major natural factors causing local rock masses to face considerable risks of damage due to constant freeze-thaw cycles. In addition, these are exacerbated by the dense acidic environments in certain industrialized areas, such as Northern Sinkiang, China. To provide local engineering design with workable solutions, it is crucial to analyze the mechanical performance of rock masses and its mechanisms under the coupling action of corrosive acid and freeze-thaw cycles. In this study, granite samples from the northern Tien Shan Mountains near Urumchi, Xinjiang Province, as well as two kinds of sandstone samples for comparison, were subjected to different soaking conditions, including nitric acid soaking at various pH values. One or both of the freeze-thaw cycle tests and uniaxial compression test were then executed. Speculations regarding the mechanism of the performance of granite rock masses under the action of corrosive acid and freeze-thaw cycles were developed based on the results of these tests. X-ray diffraction and scanning electron microscopy were implemented to demonstrate the feasibility of the speculated mechanism. In this paper, the identification of the white crumb-like substance as SiO_(2) gel were confirmed. | Suran Wang Youliang Chen Jing Ni Guanlin Liu Tomas Manuel Fernandez-Steeger Chao Xu | 2021 | Journal of Earth Science2021，32，5： | 3 |
| 12 | The Formation Mechanism and Developmental Characteristics of Tight Oil显示文摘1 Introduction Unconventional oil and gas,a kind of resources of great exploration potential,has a wide application future.Tight oil,an important part of unconventional oil and gas,attracts much more attention.With the continuous improvement of technology exploration and the continuous exploitation of oil and gas,tight oil is widedly concerned in recent years.In order to exploite tight oil effectively,many researchers using different materials and methods to discuss | PAN Yanan JI Youliang WANG Tianyun | 2015 | Acta Geologica Sinica(English Edition)2015，89，A01： | 2 |
| 13 | The Functional Gradient Description Method of Space Coordinate Transformation显示文摘The 3-dimension coordinate datum transformation is very important in geomatics.Generally,there are small angle coordinate transformation model (i.e.,Bursa model,et al) and large angle coordinate transformation model (i.e.,Rodrigo matrix model,et al).However,these papers only focus on the fixed and static situation regardless of the small or large angle.This paper proposes the conception of coordinate transformation gradient field,which can realize the space coordinate transformation from small angle to arbitrary angle,and from static to dynamical.Based on the equivalent characteristics of the unit quaternion rotation matrix and the Rodrigo matrix,through studying the mathematical relationship between the spatial coordinate transformation and the functional gradient,we derive a functional gradient expression of the arbitrary transformation formula in space.The study shows that the essence of spatial coordinate transformation is a kind of potential field mathematically.This potential field conception can unify all the space coordinate transformations.It is the theoretical foundation for the further study of time continuous space coordinate transformation,and this study gives a new solution for the attitude determination of motion carriers. | Pengshuo DUAN Genyou LIU Youliang GONG Xiaoguang HAO Nazi WANG | 2019 | Journal of Geodesy and Geoinformation Science2019，2，1： | 2 |
| 14 | Aegilops tauschii single nucleotide polymorphisms shed light on the origins of wheat D‐genome genetic diversity and pinpoint the geographic origin of hexaploid wheat显示文摘 | Jirui Wang Ming‐Cheng Luo Zhongxu Chen Frank M. You Yuming Wei Youliang Zheng Jan Dvorak | 2013 | New Phytol2013，，3： | 2 |
| 15 | Mechanism of variations in environmental magnetic proxies of lake sediments from Nam Co, Tibet during the Holocene显示文摘High-resolution environmental records from the Tibetan Plateau are essential to understand past global climatic and environmental changes. Magnetic minerals in lake sediments are important proxies to reconstruct environmental and climatic changes. Nam Co (lake) is a typical great lake in the transitional region of southwest monsoon in the Tibetan Plateau. Previous studies have extensively focused on geochemistry, microfossils, sedimentology and biochemistry analysis of Nam Co, which provides sound interpretation of paleoclimatic and paleoenvironmental changes. However, up to now, no systematic environmental magnetic studies have been carried out. Therefore, high-resolution and systematic magnetic studies combined with geochemical parameters were carried on lake sediments of core NC 08/01 from Nam Co for the Holocene period (11.3 cal ka BP) in order to explore how magnetic properties of the sediments respond to climatic changes. Based on variations of magnetic proxies, the sequence can be separated into 3 units. Unit 1 (236-199 cm, 11.3-7.8 cal ka BP) contains dominantly coarse-grained magnetite with homogeneous grain size. A positive correlation between magnetite and Ti strongly suggests that these coarse-grained detrital magnetites reflect detrital input signals due to insignificant effects of postdepositional dissolution processes on these coarse-grained magnetite particles. For Unit 2 (198-102 cm, 7.8-2.1 cal ka BP), magnetic grain size is finer and the corresponding concentration of magnetite is also reduced. This is mainly due to significant dissolution of these fine-grained detrital magnetite particles, which were transported under reduced water flow conditions during this period. For Unit 3 (101-0 cm, 2.1-0 cal ka BP), the bulk magnetic properties are dominated by a mixture of single domain biogenic magnetite and detrital magnetite. The concentration of magnetic minerals is not correlated with the Ti content. In conclusion, the preservation of magnetic minerals in the lake sediment and thus the corresponding magnetic properties are related to the initial grain size. Combination of magnetic properties (including variation of grain size and concentration) and other proxies of detrital inputs (e.g. Ti) can be used to infer the variation of redox conditions in Nam Co. These results provide a viable framework for reconstructing the paleoenvironmental changes of this lake. | SU YouLiang GAO Xing LIU QingSong HU PengXiang DUAN ZongQi JIANG ZhaoXia WANG JunBo ZHU LiPing DOBERSCHüTZ Stefan MUSBACHER Roland DAUT Gerhard HABERZETTL Torsten | 2013 | Chinese Science Bulletin2013，58，13： | 2 |
| 16 | Method for Predicting the Fatigue Life of Geometrically Discontinuous Structures Under Combined Bending and Torsion显示文摘The fatigue damage model based on theory of damage mechanics is capable of predicting the fatigue life under multiaxial loading. Meanwhile, the application of critical plane method in the prediction of multiaxial fatigue life has made certain progress. According to the law of thermodynamics, a new damage evolution equation is developed in the present study to predict the fatigue life of geometrically discontinuous structure under tension-torsion loading based on damage mechanics and the critical plane method. The essence of this approach is tha t the st rain parame ter of the uniaxial nonlinear fatigue damage model is replaced with the equivalent strain, which consists of the releva nt parame ters of the critical plane. However, it is difficult to calculate the stress-strain status and the critical plane position of geometrically dis? continuous structure by theoretical methods because of the existence of stress concentration and the multiaxial nonproportional characteristics. Therefore, a new numerical simulation method is proposed to determine the critical plane of geometrically discontinuous structure under multiaxial loading by means of the finite element method and MATLAB software. The fatigue life of notched specimens subjected to combined bending and torsion is predicted using the proposed met hod, and the result is compared with t hose from the experimen ts and the Manson-Cfiffin law. The comparisons show that the proposed method is superior to the Manson-Coffin law and is capable of reproducing the experimental results reasonably when the geometry of the structure is complex. It completely meets the needs of engineering practice. | Jianhui Liu Xuemei Pan Yaobing Wei Youliang Wang | 2019 | Acta Mechanica Solida Sinica2019，32，3： | 2 |
| 17 | Stable and realistic crack pattern generation using a cracking node method显示文摘 | Juan ZHANG Fuqing DUAN Mingquan ZHOU Dongcan JIANG Xuesong WANG Zhongke WU Youliang HUANG Guoguang DU Shaolong LIU Pengbo ZHOU Xiangang SHANG | 2018 | Frontiers of Computer Science2018，12，4： | 1 |
| 18 | Cloning and expression of a pectate lyase gene from Bacillus alcalophillus NTT33显示文摘 | Zhai Chao Cao Junwei Wang Youliang | | 0，，02： | 1 |
| 19 | Rice gene OsNAC19 encodes a novel NAC-domain transcription factor and responds to infection by Magnaporthe grisea显示文摘 | Ruiming Lin Wensheng Zhao Xiangbing Meng Min Wang Youliang Peng | 2006 | Plant Science2006，，1： | 1 |
| 20 | Nitric oxide enhances salt tolerance in maize seedlings through increasing activities of proton-pump and Na + /H + antiport in the tonoplast显示文摘 | Yanyan Zhang Liling Wang Youliang Liu Qun Zhang Qiuping Wei Wenhua Zhang | 2006 | Planta2006，，： | 1 |
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