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| 1 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021，3，21： | 16 |
| 2 | Mushroom Poisoning Outbreaks-China,2020显示文摘What is already known about this topic?Acute liver failure,rhabdomyolysis,acute renal failure,and hemolysis caused by poisonous mushrooms are the most important mushroom poisoning threats to the Chinese population.The most notorious lethal mushrooms are the species from genera Amanita,Lepiota,and Galerina that cause acute liver failure,and Russula subnigricans that leads to rhabdomyolysis.What is added by this report?In 2020,the total number of investigations reached 676,involving an estimated 102 species of poisonous mushrooms,24 of which were newly recorded in China.Gyromitra venenata was newly discovered in incidents in Yunnan and Guizhou provinces and were the first reported poisonings due to gyromitrins in China since 2000.The rare poisoning Shiitake mushroom dermatitis was recorded in China.Hemolysis poisoning caused by Paxillus involutus was recorded for the second time since the beginning of the new century,resulting in one death in Inner Mongolia Autonomous Region.What are the implications for public health practice?Promoting knowledge about safe consumption of mushrooms is essential to reduce mushroom poisonings.It is not wise to collect and eat wild mushrooms.For southwestern provinces such as Yunnan,especially,caution must be exercised with unfamiliar mushroom species. | Haijiao Li Hongshun Zhang Yizhe Zhang Jing Zhou Yu Yin Qian He Shaofeng Jiang Peibin Ma Yutao Zhang Ke Wen Yuan Yuan Nan Lang Bowen Cheng Junjia Lu Chengye Sun | 2021 | China CDC weekly2021，3，3： | 13 |
| 3 | Mushroom Poisoning Outbreaks--China,2019显示文摘What is already known about this topic?Mushroom poisoning is becoming one of the most serious food safety issues in China,which is responsible for nearly a half of all oral poisoning deaths.What is added by this report?In China,many mushrooms were previously“recorded”as poisonous.In this study,about 70 species obtained from mushroom poisoning incidents including several new records were confirmed accurately by morphological and molecular evidence in 2019,and spatial and temporal distribution characters of 13 lethal mushrooms were summarized systematically.What are the implications for public health practice?Precise and timely species identification is of pivotal importance in mushroom incidents.More efforts and cooperation are continued to be needed urgently for the governments,CDC staff,doctors and mycologists in future. | Haijiao Li Hongshun Zhang Yizhe Zhang Kaiping Zhang Jing Zhou Yu Yin Shaofeng Jiang Peibin Ma Qian He Yutao Zhang Ke Wen Yuan Yuan Nan Lang Junjia Lu Chengye Sun | 2020 | China CDC weekly2020，2，2： | 11 |
| 4 | Mushroom Poisoning Outbreaks — China, 2021显示文摘Summary What is already known about this topic?Mushroom poisoning is one of the most serious food safety issues in China.Most poisoning incidents resulted from eating mushrooms causing gastroenteritis and psycho-neurological disorder from which patients usually could fully recover.Most deaths resulted from species causing acute liver failure and rhabdomyolysis,and the remaining deaths were attributed to acute renal failure and hemolysis.What is added by this report?In 2021,the total number of investigations was 327 from 25 provincial-level administrative divisions,involving 923 patients and 20 deaths,and the overall mortality was 2.17%.Overall,74 poisonous mushrooms causing 6 different clinical syndromes were successfully identified,15 of which were newly recorded in China as poisonous mushrooms.What are the implications for public health practice?Considering the potential huge risks for collecting and eating wild mushrooms,we strongly advise not collecting and eating unfamiliar wild mushrooms.Promoting knowledge about poisonous mushrooms is essential and urgent to reduce mushroom poisonings.Precise species identification timely after mushroom poisoning is important for appropriate diagnosis and treatment.Many deaths were ascribed to delayed hospitalization. | Haijiao Li Hongshun Zhang Yizhe Zhang Jing Zhou Yu Yin Qian He Shaofeng Jiang Peibin Ma Yutao Zhang Yuan Yuan Nan Lang Bowen Cheng Mei Wang Chengye Sun | 2022 | China CDC weekly2022，4，3： | 7 |
| 5 | PLMD:An updated data resource of protein lysine modifications显示文摘Post-translational modifications(PTMs) occurring at protein lysine residues,or protein lysine modifications(PLMs),play critical roles in regulating biological processes.Due to the explosive expansion of the amount of PLM substrates and the discovery of novel PLM types,here we greatly updated our previous studies,and presented a much more integrative resource of protein lysine modification database(PLMD).In PLMD,we totally collected and integrated 284,780 modification events in 53,501 proteins across 176 eukaryotes and prokaryotes for up to 20 types of PLMs,including ubiquitination,acetylation,sumoylation,methylation,succinylation,malonylation,glutarylation,giycation,formylation,hydroxylation,butyrylation,propionylation,crotonylation,pupylation,neddylation,2-hydroxyisobutyrylation,phosphoglycerylation,carboxylation,lipoylation and biotinylation.Using the data set,a motif-based analysis was performed for each PLM type,and the results demonstrated that different PLM types preferentially recognize distinct sequence motifs for the modifications.Moreover,various PLMs synergistically orchestrate specific cellular biological processes by mutual crosstalks with each other,and we totally found 65,297 PLM events involved in 90 types of PLM co-occurrences on the same lysine residues.Finally,various options were provided for accessing the data,while original references and other annotations were also present for each PLM substrate.Taken together,we anticipated the PLMD database can serve as a useful resource for further researches of PLMs.PLMD 3.0 was implemented in PHP + MySQL and freely available at http://gffzz60b5e5c25d7e4f27h9p9ubfp6ccxo6k60.ffgz.tsg.suse.edu.cn. | Haodong Xu Jiaqi Zhou Shaofeng Lin Wankun Deng Ying Zhang Yu Xue | 2017 | Journal of Genetics and Genomics2017，44，5： | 6 |
| 6 | Mushroom Poisoning Outbreaks -China, 2022显示文摘Mushroom poisoning has become a serious food safety issue in China.With the support of the government,over the past decade,China has gradually established a mushroom poisoning prevention and treatment system involving experts in disease prevention and control,clinical diagnosis and treatment,fungal classification,and basic medicine(1–3). | Haijiao Li Yizhe Zhang Hongshun Zhang Jing Zhou Jiaqi Liang Yu Yin Qian He Shaofeng Jiang Yutao Zhang Yuan Yuan Nan Lang Bowen Cheng Mei Wang Chengye Sun | 2023 | China CDC weekly2023，5，3： | 4 |
| 7 | Insight into the structural evolution of porous and fractured media by forced aeration during heap leaching显示文摘Despite lots of techniques in improving the heap leaching performance,many constraints on the industrial applications remain.We proposed a correspondingly effective and new idea of introducing forced aeration to improve the bad permeability and leaching effect of Yangla Copper Mine(YCM)during heap leaching.The dual-media theory was employed to study the impact mechanism of forced aeration on the variations of porous and fractured media during the column leaching experiments.An X-Ray Computed Tomography(CT)set was utilized to perform the pore imaging of the specimens and the fracture morphology of the particles within the columns was analyzed by Scanning Electron Microscope(SEM)as aeration rate(AR)changed.The results show that there exists copious fine particles within the heap of YCM,the particle size distribution of which is not reasonable.The forced aeration can not only promote the development of the porous and fractured structures but effectively break the blocked seepage paths.Then the leaching degree is improved and the seepage performance of the solute within the solution is enhanced.Therefore,the forced aeration is probable of making the leaching performance greatly improved. | Yu Shaofeng Wu Aixiang Wang Yiming | 2019 | International Journal of Mining Science and Technology2019，29，5： | 3 |
| 8 | Preparation of SGO-modified nanofiltration membrane and its application in SO_4^(2-) and Cl^- separation in salt treatment显示文摘The lack of fresh water in the world makes the search for an effective method to decontaminate water an urgent priority.An important step is to remove different multivalent ions in salt treatment.Nanofiltration(NF)has been used for treating water containing different kinds of salts.In this work,sulfonate group-modified graphene oxide(SGO)was prepared,and added during the interfacial polymerization(IP)reaction to prepare SGO-modifiedNF membranes(PA-SGO).The chemical composition,structure and surface properties of PA and PA-SGO membranes were characterized by FT-IR,XPS,SEM,AFM,contact angle and zeta potential measurements.Their water flux,salt rejection and antifouling abilities were investigated systematically.The testing results showed that the water flux of PA-SGO(0.03%SGO)was 45.85 LMH under a pressure of 0.2 MPa,and the salt rejection varied in the order of Na_2SO_4(98.99%)>MgSO_4(91.25%)>MgCl_2(42.27%)>NaCl(21.96%).An anti-fouling experiment indicated that the PA-SGO membrane had good anti-fouling properties because of its decreased roughness and increased hydrophilicity and electronegativity.The PA-SGO membrane has good potential for use in removing salt ions from water. | Yanjun Zhang Changwei Zhao Shaofeng Zhang Ling Yu Jiding Li Li-an Hou | 2019 | Journal of Environmental Sciences2019，31，4： | 2 |
| 9 | Dynamic response of ultralight all-metallic sandwich panel with 3D tube cellular core to shallow-buried explosives显示文摘The underbody of a vehicle system, either military or civil, is typically made of a relatively thin metallic plate, thus vulnerable to mine blast attacks. To improve the blast resistance, a multitude of protective structures have been proposed as attachments to the thin plate. In the present study, a novel ultralight all-metallic sandwich panel with three-dimensional(3D) tube cellular cores mounted to the vehicle underbody was envisioned as such a protective system. A metallic substrate(mimicking vehicle bottom)was placed above the proposed sandwich panel to construct a sandwich-substrate combinative structure. A series of sandwich panels having 3D tube cellular cores were fabricated via argon protected welding and laser welding. Mechanical responses of the combinative structure subjected to the denotation of 6 kg TNT explosives shallow-buried in dry sand were experimentally measured. Full numerical simulations with the method of finite elements(FE) were subsequently carried out to explore the physical mechanisms underlying the observed dynamic performance and quantify the effects of key geometrical parameters and connection conditions of the protective system. The performance of the proposed sandwich panel under shallow-buried explosives was also compared with competing sandwich constructions having equal mass. Finally, a preliminary optimal design of the 3D tube cellular core was carried out. | ZHANG DuJiang ZHAO Zhen Yu DU ShaoFeng CHEN WeiJie YANG Fan NI ChangYe YANG ZhiKun LU TianJian | 2021 | Science China(Technological Sciences)2021，64，7： | 2 |
| 10 | PTMD: A Database of Human Disease-associated Post-translational Modifications显示文摘Various posttranslational modifications(PTMs) participate in nearly all aspects of biological processes by regulating protein functions, and aberrant states of PTMs are frequently implicated in human diseases. Therefore, an integral resource of PTM–disease associations(PDAs)would be a great help for both academic research and clinical use. In this work, we reported PTMD,a well-curated database containing PTMs that are associated with human diseases. We manually collected 1950 known PDAs in 749 proteins for 23 types of PTMs and 275 types of diseases from the literature. Database analyses show that phosphorylation has the largest number of disease associations, whereas neurologic diseases have the largest number of PTM associations. We classified all known PDAs into six classes according to the PTM status in diseases and demonstrated that the upregulation and presence of PTM events account for a predominant proportion of diseaseassociated PTM events. By reconstructing a disease–gene network, we observed that breast cancershave the largest number of associated PTMs and AKT1 has the largest number of PTMs connected to diseases. Finally, the PTMD database was developed with detailed annotations and can be a useful resource for further analyzing the relations between PTMs and human diseases. PTMD is freely accessible at http://gffzz7d3e84778ac14081h9p9ubfp6ccxo6k60.ffgz.tsg.suse.edu.cn. | Haodong Xu Yongbo Wang Shaofeng Lin Wankun Deng Di Peng Qinghua Cui Yu Xue | 2018 | Genomics, Proteomics & Bioinformatics2018，16，4： | 2 |
| 11 | The preparation and mechanism studies of rice husk based porous carbon 显示文摘 | GUO Yupeng YANG Shaofeng YU Kaifeng | 2002 | Materials Chemistry and Physics2002，74，： | 1 |
| 12 | Hexamethylenetetramine directed synthesis and properties of a new family of α-nickel hydroxide organic-inorganic hybrid materials with high chemical stability显示文摘 | Bianhua Liu Shuhong Yu Shaofeng Chen | | 0，，09： | 1 |
| 13 | The preparation and mechanism studies of rice husk based porous carbon显示文摘 | GOU Yupeng YANG Shaofeng YU Kaifeng | 2002 | Mater Chem Phys2002，74，2： | 1 |
| 14 | Polymorph discrimination of CaCO3 mineral in an Ethanol/Water solution:formation of complex vaterite superstructures and aragonite rods显示文摘 | Chen Shaofeng Yu Shuhong Jiang Jun | 2006 | Chem Mater2006，18，： | 1 |
| 15 | An electrocatalyst with anti-oxidized capability for overall water splitting显示文摘 | Chang Yu Huawei Huang Si Zhou Xiaotong Han Changtai Zhao Juan Yang Shaofeng Li Wei Guo Bowen An Jijun Zhao Jieshan Qiu | 2018 | Nano Research2018，11，6： | 1 |
| 16 | Polymorph discrimination of CaCO3 mineral in an ethanol/water solution:formation of complex vaterite superstructures and aragonite rods显示文摘 | Chen Shaofeng Yu Shuhong Jiang Jun | 2006 | Chemistry of Materials2006，18，1： | 1 |
| 17 | Combined nanosuspensions from two natural active ingredients for cancer therapy with reduced side effects显示文摘Tumor drug resistance and systemic side effects of chemotherapeutic drugs are the main reasons for the failure of cancer treatment.In recent years,it was found that some natural active ingredients can reverse MDR and regulate body immunity to enhance the efficacy and reduce toxicity of chemotherapeutic drugs.In this paper,a new nanosuspensions,HCPT and QUR hybrid nanosuspensions(HQ-NPs),was prepared by the microprecipitation-high pressure homogenization method to reverse tumor drug resistance,reduce toxicity,and increase therapeutic efficacy.The in vitro investigation results showed that HQ-NPs had a unique shape(particle size was about 216.3±5.9 nm),changed crystalline,and different dissolution rates compared with HCPT-NPs and QUR-NPs,which is attributed to the strong intermolecular forces between HCPT and QUR as indicated by the results of the molecule dock.It was verified that the HQ-NPs could double the retention of HCPT in cells and enhance the cytotoxicity to A549/PTX cells in vitro tests compared with HCPT-NPs.We also found that HQ-NPs can significantly enhance the accumulation of HCPT in tumor sites,improve the antitumor activity of HCPT,and protect the immune organs and other normal tissues(P<0.01),compared with HCPT-NPs.Therefore,hybrid nanosuspensions can offer promising potential as the drug delivery system for HCPT and QUR to increase the therapeutic efficacy and reduce the toxicity of HCPT. | Yonghui Qiao Zhihao Wei Tingting Qin Rufeng Song Zhiqiang Yu Qi Yuan Juan Du Qingbing Zeng Lanlan Zong Shaofeng Duan Xiaohui Pu | 2021 | Chinese Chemical Letters2021，32，9： | 1 |
| 18 | Large scale synthe-sis of uniform CuS nanotubes in ethylene glycol by a sacrificialtemplating method under mild conditions显示文摘 | Wu Chunyan Yu Shuhong Chen Shaofeng | 2006 | Journal of Materi-als Chemistry2006，16，： | 1 |
| 19 | Waterborne Arsenic Poisoning Caused by Discarded Slags--Yongzhou City,Hunan Province,China,2018显示文摘What is already known about this topic?Overexposure to arsenic is toxic and affects bodily systems.In severe cases,loss of motor function and death can occur.What is added by this report?At the end of 2018,a waterborne acute arsenic poisoning event occurred in Yongzhou City of Hunan Province because arsenic-containing slags contaminated the water supply,which resulted in 10 people being poisoned.Patients were poisoned through domestic use of contaminated well water excluding drinking.What are the implications for public health practice?Clinicians should be trained to correctly and promptly identify and diagnose acute arsenic poisoning.The arsenic slags and byproducts should be strictly managed by corresponding enterprises to avoid similar poisoning incidents.When dealing with such events,water intended for domestic use should be closely monitored and environmental pollution should be assessed and controlled. | Junjia Lu Yan Lai Shaofeng Jiang Peibin Ma Lei Huang Yimei Yang Fangkun Tang Chuntao Huang Lun Hong Yu Yin Chengye Sun | 2020 | China CDC weekly2020，2，32： | 1 |
| 20 | WocEA:The visualization of functional enrichment results in word clouds显示文摘The integration,analysis and visualization of the big omics data are critical for addressing a broad spectrum of biological questions.One of the most frequently conducted procedures is enrichment analysis,which statistically tests whether individual functional annotations of Gene Ontology (GO)or Kyoto Encyclopedia of | Wanshan Ning Shaofeng Lin Jiaqi Zhou Yaping Guo Ying Zhang Di Peng Wankun Deng Yu Xue | 2018 | Journal of Genetics and Genomics2018，45，7： | 1 |
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